TRIM21 immune signaling is more sensitive to antibody affinity than its neutralization activity

Journal of Immunology

Volumn 196, Issue 8, 2016, Pages 3452-3459

  Foss, Stian ^a,b   Watkinson, Ruth E ^c   Grevys, Algirdas ^a,b   McAdam, Martin B ^b   Bern, Malin ^a,b   Høydahl, Lene Stokken ^a,b   Dalhus, Bjørn ^b   Michaelsen, Terje E ^a,d   Sandlie, Inger ^a,b   James, Leo C ^c   Andersen, Jan Terje ^a,b  

^a UNIVERSITY OF OSLO   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^d NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G1; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; TRIM21 PROTEIN; UNCLASSIFIED DRUG; VIRUS ANTIBODY; IMMUNOGLOBULIN G; NEUTRALIZING ANTIBODY; RIBONUCLEOPROTEIN; SS-A ANTIGEN;

ANTIBODY AFFINITY; ARTICLE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN ADENOVIRUS 5; HUMAN CELL; IMMUNE SIGNALING; IMMUNITY; IMMUNOSTIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; VIRUS NEUTRALIZATION; VIRUS PARTICLE; ANIMAL; C57BL MOUSE; CELL LINE; GENETICS; HEK293 CELL LINE; HUMAN ADENOVIRUS C; IMMUNOLOGY; KNOCKOUT MOUSE; MOUSE; SERODIAGNOSIS; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE;

ADENOVIRUSES, HUMAN; ANIMALS; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTIBODIES, NEUTRALIZING; ANTIBODY AFFINITY; CELL LINE; HEK293 CELLS; HUMANS; IMMUNOGLOBULIN G; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEUTRALIZATION TESTS; NF-KAPPA B; RIBONUCLEOPROTEINS; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE;

EID: 84974805110     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1502601     Document Type: Article

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