25 Years of Tension over Actin Binding to the Cadherin Cell Adhesion Complex: The Devil is in the Details

Trends in Cell Biology

Volumn 26, Issue 7, 2016, Pages 471-473

  Nelson, W James ^a   Weis, William I ^a  

^a STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; CADHERIN; ACTIN;

ACTIN FILAMENT; CELL ADHESION; CONFORMATIONAL TRANSITION; EXTRACELLULAR MATRIX; MACHINE; NOTE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; ANIMAL; BIOMECHANICS; HUMAN; METABOLISM;

ACTINS; ANIMALS; BIOMECHANICAL PHENOMENA; CADHERINS; CELL ADHESION; HUMANS;

EID: 84974694613     PISSN: 09628924     EISSN: 18793088     Source Type: Journal    
DOI: 10.1016/j.tcb.2016.04.010     Document Type: Note

References (15)

1. Drees F., et al. Alpha-catenin is a molecular switch that binds E-cadherin/b-catenin and regulates actin filament assembly. Cell 2005, 123:903-915.
2. Choi H.J., et al. alphaE-catenin is an autoinhibited molecule that coactivates vinculin. Proc Natl Acad Sci U S A. 2012, 109:8576-8581.
3. Rangarajan E.S., Izard T. Dimer asymmetry defines alpha-catenin interactions. Nat Struct. Mol. Biol. 2013, 20:188-193.
4. Abe K., Takeichi M. EPLIN mediates linkage of the cadherin-catenin complex to F-actin and stabilizes the circumferential actin belt. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:13-19.
5. Burridge K. Cell biology: a break in the chain?. Nature 2006, 440:38-39.
6. le Duc Q., et al. Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II-dependent manner. J Cell Biol. 2010, 189:1107-1115.
7. Yonemura S., et al. Alpha-Catenin as a tension transducer that induces adherens junction development. Nat. Cell Biol. 2010, 12:533-542.
8. Yao M., et al. Force-dependent conformational switch of alpha-catenin controls vinculin binding. Nat. Commun. 2014, 5:4525.
9. Buckley C.D., et al. Cell adhesion. The minimal cadherin-catenin complex binds to actin filaments under force. Science 2014, 346:1254211.
10. Borghi N., et al. E-cadherin is under constitutive actomyosin-generated tension that is increased at cell-cell contacts upon externally applied stretch. Proc Natl Acad Sci U S A. 2012, 109:12568-12573.
11. Bakolitsa C., et al. Structural basis for vinculin activation at sites of cell adhesion. Nature 2004, 430:583-586.
12. Brasch J., et al. Thinking outside the cell: how cadherins drive adhesion. Trends Cell Biol. 2012, 22:299-310.
13. Wu Y., et al. Actin-delimited adhesion-independent clustering of E-cadherin forms the nanoscale building blocks of adherens junctions. Dev. Cell 2015, 32:139-154.
14. Kobielak A., et al. Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables. Nat. Cell Biol. 2004, 6:21-30.
15. Mason F.M., et al. Apical domain polarization localizes actin-myosin activity to drive ratchet-like apical constriction. Nat. Cell Biol. 2013, 15:926-936.