Force-dependent conformational switch of α -catenin controls vinculin binding

Nature Communications

Volumn 5, Issue , 2014, Pages

  Yao, Mingxi ^a   Qiu, Wu ^a,b   Liu, Ruchuan ^a,b   Efremov, Artem K ^a   Cong, Peiwen ^a   Seddiki, Rima ^c   Payre, Manon ^c   Lim, Chwee Teck ^a   Ladoux, Benoit ^a,c   Mège, René Marc ^c   Yan, Jie ^a,b,d  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b CHONGQING UNIVERSITY   (China)

^c INSTITUT JACQUES MONOD   (France)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CATENIN; INTEGRIN; VINCULIN; HYBRID PROTEIN; PROTEIN BINDING;

BIOCHEMICAL COMPOSITION; INHIBITOR; PHYSIOLOGY; PROTEIN; STABILIZATION; X-RAY;

ALPHA HELIX; ARTICLE; BINDING SITE; DIFFRACTION; FORCE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN UNFOLDING; ACTIN FILAMENT; ANIMAL; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; MAGNETIC FIELD; MECHANICAL STRESS; MECHANOTRANSDUCTION; METABOLISM; MOUSE; OPTICAL TWEEZERS; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

ACTIN CYTOSKELETON; ALPHA CATENIN; ANIMALS; BINDING SITES; GENE EXPRESSION REGULATION; MAGNETIC FIELDS; MECHANOTRANSDUCTION, CELLULAR; MICE; OPTICAL TWEEZERS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; STRESS, MECHANICAL; VINCULIN;

EID: 84905482347     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5525     Document Type: Article

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