Challenges for malaria elimination in Brazil

Malaria Journal

Volumn 15, Issue 1, 2016, Pages

  Ferreira, Marcelo U ^a   Castro, Marcia C ^b  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Brazil; Malaria; Malaria control; Malaria control challenges; Malaria elimination

Indexed keywords

ANTIMALARIAL AGENT; ARTEMETHER PLUS BENFLUMETOL; ARTEMISININ; ARTESUNATE PLUS MEFLOQUINE; CHLOROQUINE; CHLORPHENOTANE; DOXYCYCLINE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; INSECTICIDE; MEFLOQUINE; PRIMAQUINE; PYRIMETHAMINE PLUS SULFADOXINE; QUININE; TAFENOQUINE; TETRACYCLINE;

ANOPHELES; ANOPHELES ARABIENSIS; ANOPHELES DARLINGI; ANOPHELES GAMBIAE; ANTIMALARIAL DRUG RESISTANCE; BED NET; BRAZIL; BROMELIAD MALARIA; CLIMATE CHANGE; DISEASE SURVEILLANCE; ENVIRONMENTAL CHANGE; ENVIRONMENTAL FACTOR; HIGH RISK PREGNANCY; HISTORY OF MEDICINE; HUMAN; INSECTICIDE TREATED BED NET; LONG LASTING INSECTICIDE TREATED BED NET; MALARIA; MALARIA CONTROL; MALARIA FALCIPARUM; MALARIA IN PREGNANCY; NONHUMAN; NUCLEIC ACID AMPLIFICATION; PARASITE LOAD; PESTICIDE SPRAYING; PLASMODIUM FALCIPARUM; PLASMODIUM MALARIAE; PLASMODIUM VIVAX; PLASMODIUM VIVAX MALARIA; POLYMERASE CHAIN REACTION; PRACTICE GUIDELINE; PREGNANCY; REVIEW; SEROLOGY; SPECIES DISTRIBUTION; SPECIES DIVERSITY; VECTOR CONTROL; WORLD HEALTH ORGANIZATION; COMMUNICABLE DISEASE CONTROL; DISEASE ERADICATION; DISEASE TRANSMISSION; EPIDEMIOLOGICAL MONITORING; EPIDEMIOLOGY; HEALTH CARE POLICY; MALARIA, FALCIPARUM; MALARIA, VIVAX; ORGANIZATION AND MANAGEMENT; PREVENTION AND CONTROL; PROCEDURES; TRANSMISSION;

BRAZIL; COMMUNICABLE DISEASE CONTROL; DISEASE ERADICATION; DISEASE TRANSMISSION, INFECTIOUS; EPIDEMIOLOGICAL MONITORING; HEALTH POLICY; HUMANS; MALARIA, FALCIPARUM; MALARIA, VIVAX;

EID: 84974686956     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/s12936-016-1335-1     Document Type: Review

References (199)

1. Pan American Health Organization. Interactive malaria statistics. Washington, DC: PAHO; 2016. http://www.paho.org/hq/index.php?option=com-content&task=view&id=2632&Itemid=2130. Accessed 1 Feb 2016.
2. Tatem AJ, Smith DL, Gething PW, Kabaria CW, Snow RW, Hay SI. Ranking of elimination feasibility between malaria-endemic countries. Lancet. 2010;376:1579-91.
3. Deane LM. Malaria studies and control in Brazil. Am J Trop Med Hyg. 1988;38:223-30.
4. Chagas C. Luta Contra a Malária. Rio de Janeiro; 1934. p. 24.
5. Cruz O. Prophylaxis of malaria in central and southern Brazil. In: Ross R, editor. The prevention of malaria. New York: E.P. Dutton & Company; 1910. p. 390-9.
6. Silveira AC, Rezende DF. Avaliação da estratégia global de controle integrado da malária no Brasil. Brasília: Organização Pan-Americana da Saúde; 2001. p. 120.
7. Deane LM. A história da evolução dos conhecimentos sobre a malária. Rio de Janeiro; 1986. p. 51.
8. Hochman G, Mello MTB, Santos PRE. A malária em foto: imagens de campanhas e ações no Brasil da primeira metade do século XX. Hist Ciênc Saúde. 2002;9:233-73.
9. Neiva A. Profilaxia da malaria e trabalhos de engenharia: notas, comentários, recordações. Revista do Clube de Engenharia, vol. VI. 1940. p. 60-75.
10. Parmakelis A, Russello MA, Caccone A, Marcondes CB, Costa J, Forattini OP, et al. Historical analysis of a near disaster: Anopheles gambiae in Brazil. Am J Trop Med Hyg. 2008;78:176-8.
11. a Reunião Brasileira sobre Simulídeos. III Seminário de Vetores Urbanos e Animais Sinatrópicos - 4a. Reunião Brasileira sobre Simulídeos. Rio de Janeiro; 1990.
12. Soper FL, Wilson DB. Anopheles gambiae in Brazil, 1930 to 1940. New York City: Rockefeller Foundation; 1943.
13. Farid MA. The malaria programme - from euphoria to anarchy. World Health Forum. 1980;1:8-33.
14. Norman TJ, Baley MA. The biomathematics of malaria. London: Oxford University Press; 1982.
15. Litsios S. The tomorrow of malaria. Wellington: Pacific Press; 1997. p. 186.
16. Pina-Costa A, Brasil P, Santi SMD, de Araujo MP, Suárez-Mutis MC, Santelli ACFS, et al. Malaria in Brazil: what happens outside the Amazonian endemic region. Mem Inst Oswaldo Cruz. 2014;109:618-33.
17. Silva R, Paiva CHA. The Juscelino Kubitschek government and the Brazilian Malaria Control and Eradication Working Group: collaboration and conflicts in Brazilian and international health agenda, 1958-1961. Hist Ciênc Saúde Manguinhos. 2015;22:95-114.
18. Tauil P, Deane L, Sabroza P, Ribeiro C. A malária no Brasil. Cad Saude Publ. 1985;1:71-111.
19. Nájera JA, González-Silva M, Alonso PL. Some lessons for the future from the Global Malaria Eradication Programme (1955-1969). PLoS Med. 2011;8:e1000412.
20. Silva R, Hochman G. Um método chamado Pinotti: sal medicamentoso, malária e saúde internacional (1952-1960). Hist Ciênc, Saúde Manguinhos. 2011;18:519-44.
21. Pinotti M, Lôbo AGS, Damasceno G, Soares R. Experiências de campo com o sal cloroquinado. Revista Brasileira de Malariologia e Doenças Tropicais. 1955;7:5-23.
22. Clyde DF. Suppression of malaria in Tanzania with the use of medicated salt. Bull World Health Organ. 1966;35:962-8.
23. Giglioli G, Rutten FJ, Ramjattan S. Interruption of malaria transmission by chloroquinized salt in Guyana, with observations on a chloroquine-resistant strain of Plasmodium falciparum. Bull World Health Organ. 1967;36:283-301.
24. Coimbra MELS. Política pública e saúde: o caso da malária no Brasil. Análise e Conjuntura. 1987;2:72-90.
25. Val FF, Sampaio VS, Cassera MB, Andrade RT, Tauil PL, Monteiro WM, et al. Plasmodium vivax malaria elimination: should innovative ideas from the past be revisited? Mem Inst Oswaldo Cruz. 2014;109:522-4.
26. Sawyer DR. Frontier malaria in the Amazon region of Brazil: types of malaria situations and some implications for control. Brasília: PAHO/WHO/TDR; 1988.
27. Mahar DJ. Frontier development policy in Brazil: a study of Amazonia. New York: Praeger; 1979.
28. Silva GC. Geopolítica do Brasil. Rio de Janeiro: José Olympio; 1967.
29. Marques AC. Human migration and the spread of malaria in Brazil. Parasitol Today. 1987;3:166-70.
30. Sant'Ana MMM. Uma avaliação das políticas recentes de desenvolvimento regional no Brasil: Programa de Desenvolvimento da Região Noroeste - POLONOROESTE. Revista Econômica do Nordeste. 1994;25:499-528.
31. Martine G. Rondônia and the fate of small producers. In: Goodman D, Hall AL, editors. The future of Amazonia: destruction or sustainable development?. Basingstoke: Macmillan Press; 1990. p. 23-48.
32. Perdigão F, Bassegio L. Migrantes Amazônicos - Rondônia: a trajetória da ilusão. São Paulo: Edições Loyola; 1992.
33. World Bank. World Bank approaches to the environment in Brazil: a review of selected projects. In: The POLONOROESTE program, vol. 5. Washington: The World Bank; 1992. p. 344.
34. Fearnside PM. Deforestation in Brazilian Amazonia: history, rates, and consequences. Conservat Biol. 2005;19:680-8.
35. Castro MC, Monte-Mór RL, Sawyer DO, Singer BH. Malaria risk on the Amazon frontier. Proc Natl Acad Sci USA. 2006;103:2452-7.
36. Sawyer DR, Sawyer DO. The malaria transition and the role of social science research. In: Chen LC, editor. Advancing the health in developing countries: the role of social research. Westport: Auburn House; 1992. p. 105-22.
37. Sinka ME, Rubio-Palis Y, Manguin S, Patil AP, Temperley WH, Gething PW, et al. The dominant Anopheles vectors of human malaria in the Americas: occurrence data, distribution maps and bionomic précis. Parasit Vectors. 2010;3:72.
38. Hahn MB, Gangnon RE, Barcellos C, Asner GP, Patz JA. Influence of deforestation, logging, and fire on malaria in the Brazilian Amazon. PLoS One. 2014;9:e85725.
39. Vittor AY, Gilman RH, Tielsch J, Glass G, Shields T, Lozano WS, et al. The effect of deforestation on the human-biting rate of Anopheles darlingi, the primary vector of falciparum malaria in the Peruvian Amazon. Am J Trop Med Hyg. 2006;74:3-11.
40. Vittor AY, Pan W, Gilman RH, Tielsch J, Glass G, Shields T, et al. Linking deforestation to malaria in the Amazon: characterization of the breeding habitat of the principal malaria vector, Anopheles darlingi. Am J Trop Med Hyg. 2009;81:5-12.
41. Barbieri AF, Sawyer DO, Soares-Filho B. Population and land use effects on malaria prevalence in the Southern Brazilian Amazon. Human Ecol. 2005;33:847-74.
42. Sawyer D. Economic and social consequences of malaria in new colonization projects in Brazil. Soc Sci Med. 1993;37:1131-6.
43. Silva LCE. O que mostram os indicadores sobre a pobreza na década perdida. Brasília: Instituto de Pesquisa Econômica Aplicada - IPEA. Textos para Discussão. 1992. p. 274.
44. Cavasini MTV, Ribeiro WL, Kawamoto F, Ferreira MU. How prevalent is Plasmodium malariae in Rondônia, Western Brazilian Amazon? Rev Soc Bras Med Trop. 2000;33:489-92.
45. Scopel KKG, Fontes CJ, Nunes AC, Horta MF, Braga EM. High prevalence of Plasmodium malariae infections in a Brazilian Amazon endemic area (Apiacás-Mato Grosso State) as detected by polymerase chain reaction. Acta Trop. 2005;90:61-4.
46. Cheng Q, Cunningham J, Gatton ML. Systematic review of sub-microscopic P. vivax infections: prevalence and determining factors. PLoS Negl Trop Dis. 2015;9:e3413.
47. White NJ, Imwong M. Relapse. Adv Parasitol. 2012;80:113-50.
48. Luzzatto L, Seneca E. G6PD deficiency: a classic example of pharmacogenetics with on-going clinical implications. Br J Haematol. 2014;164:469-80.
49. Douglas NM, Simpson JA, Phyo AP, Siswantoro H, Hasugian AR, Kenangalem E, et al. Gametocyte dynamics and the role of drugs in reducing the transmission potential of Plasmodium vivax. J Infect Dis. 2013;208:801-12.
50. Lima NF, Bastos MS, Ferreira MU. Plasmodium vivax: reverse transcriptase real-time PCR for gametocyte detection and quantitation in clinical samples. Exp Parasitol. 2012;132:348-54.
51. Akhavan D, Musgrove P, Abrantes A, Gusmão RA. Cost-effective malaria control in Brazil: cost-effectiveness of a malaria control program in the Amazon Basin of Brazil, 1988-1996. Soc Sci Med. 1999;49:1385-99.
52. Loiola CCP, Silva CJM, Tauil PL. Controle da malária no Brasil: 1965 a 2001. Pan Am J Public Health. 2002;11:235-44.
53. Guimarães RM, Asmus CI, Meyer A. DDT reintroduction for malaria control: the cost-benefit debate for public health. Cad Saude Publ. 2007;23:2835-44.
54. Ministério da Saúde, Secretaria de Vigilância em Saúde. Plano de Intensificação das Ações de Controle da Malária na Amazônia Legal - Relatório Executivo. Brasília: Ministério da Saúde, Secretaria de Vigilância em Saúde; 2000.
55. Ministério da Saúde, Secretaria de Vigilância em Saúde. Programa Nacional de Prevenção e Controle da Malária - PNCM. Brasília: Ministério da Saúde, Secretaria de Vigilância em Saúde; 2003. p. 132.
56. Ferreira MU, da Silva-Nunes M. Evidence-based public health and prospects for malaria control in Brazil. J Infect Dev Ctries. 2010;4:533-45.
57. WHO. Health in 2015: from MDGs, millennium development goals to SDGs, sustainable development goals. Geneva: World Health Organization; 2015. p. 216.
58. Ministério da Saúde. Ministério da Saúde lança Plano de Eliminação da malária no Brasil. 2015. http://portalsaude.saude.gov.br/index.php/cidadao/principal/agencia-saude/20609-ministerio-da-saude-lanca-plano-de-eliminacao-da-malaria-no-brasil. Accessed 1 Feb 2016.
59. Ministério da Saúde. Brasil tem o menor número de casos de malária dos últimos 35 anos. 2016. http://www.brasil.gov.br/saude/2016/04/brasil-tem-o-menor-numero-de-casos-de-malaria-dos-ultimos-35-anos. Accessed 1 Apr 2016.
60. Avery-Jones S, Ferreira-Neto JA. Symptomless Plasmodium vivax parasitaemias and malaria eradication in Santa Catarina State, Brazil (WHO/MAL/64.469). Geneva: World Health Organization; 1964.
61. Marrelli MT, Malafronte RS, Sallum MA, Natal D. Kerteszia subgenus of Anopheles associated with the Brazilian Atlantic rainforest: current knowledge and future challenges. Malar J. 2007;6:127.
62. Carvalho ME, Glasser CM, Santos LA, Ciaravolo RMC. Nota sobre o encontro de casos autóctones de malária vivax por meio de técnica sorológica, em São Paulo. Cad Saude Publ. 1985;1:250-2.
63. Carvalho ME, Glasser CM, Ciaravolo RMC, Etzel A, Santos LA, Ferreira CS. Sorologia de malária vivax no foco Aldeia dos Índios, município de Peruíbe, Estado de São Paulo, 1984 a 1986. Cad Saude Publ. 1988;4:276-92.
64. Alves FP, Durlacher RR, Menezes MJ, Krieger H, Silva LHP, Camargo EP. High prevalence of asymptomatic Plasmodium vivax and Plasmodium falciparum infections in native Amazonian populations. Am J Trop Med Hyg. 2002;66:641-8.
65. Ladeia-Andrade S, Ferreira MU, Carvalho ME, Curado I, Coura JR. Age-dependent acquisition of protective immunity to malaria in riverine populations of the Amazon Basin of Brazil. Am J Trop Med Hyg. 2009;80:452-9.
66. Coura JR, Suarez-Mutis M, Ladeia-Andrade S. A new challenge for malaria control in Brazil: asymptomatic Plasmodium infection - a review. Mem Inst Oswaldo Cruz. 2006;101:229-37.
67. Prata A, Urdaneta M, McGreevy PB, Tada MS. Infrequency of asymptomatic malaria in an endemic area in Amazonas, Brazil. Rev Soc Bras Med Trop. 1988;21:51-4.
68. Camargo LM, Ferreira MU, Krieger H, de Camargo EP, da Silva LP. Unstable hypoendemic malaria in Rondônia (western Amazon region, Brazil): epidemic outbreaks and work-associated incidence in an agro-industrial rural settlement. Am J Trop Med Hyg. 1994;51:16-25.
69. Camargo LM, dal Colletto GM, Ferreira MU, Gurgel SM, Escobar AL, Marques A, et al. Hypoendemic malaria in Rondônia (Brazil, western Amazon region): seasonal variation and risk groups in an urban locality. Am J Trop Med Hyg. 1996;55:32-8.
70. Duarte EC, Gyorkos TW, Pang L, Abrahamowicz M. Epidemiology of malaria in a hypoendemic Brazilian Amazon migrant population: a cohort study. Am J Trop Med Hyg. 2004;70:229-37.
71. da Silva-Nunes M, Codeco CT, Malafronte RS, da Silva NS, Juncansen C, Muniz PT, et al. Malaria on the Amazonian frontier: transmission dynamics, risk factors, spatial distribution, and prospects for control. Am J Trop Med Hyg. 2008;79:624-35.
72. da Silva NS, da Silva-Nunes M, Malafronte RS, Menezes MJ, D'Arcadia RR, Komatsu NT, et al. Epidemiology and control of frontier malaria in Brazil: lessons from community-based studies in rural Amazonia. Trans R Soc Trop Med Hyg. 2010;104:343-50.
73. Barbosa S, Gozze AB, Lima NF, Batista CL, Bastos MS, Nicolete VC, et al. Epidemiology of disappearing Plasmodium vivax malaria: a case study in rural Amazonia. PLoS Negl Trop Dis. 2014;8:e3109.
74. da Silva-Nunes M, Ferreira MU. Clinical spectrum of uncomplicated malaria in semi-immune Amazonians: beyond the "symptomatic" vs "asymptomatic" dichotomy. Mem Inst Oswaldo Cruz. 2007;102:341-7.
75. Alves FP, Gil LHS, Marrelli MT, Ribolla PEM, Camargo EP, Silva LHP. Asymptomatic carriers of Plasmodium spp. as infection source for malaria vector mosquitoes in the Brazilian Amazon. J Med Entomol. 2005;42:777-9.
76. Sturrock HJW, Hsiang MS, Cohen JM, Smith DL, Greenhouse B, Bousema T, Gosling RD. Targeting asymptomatic malaria infections: active surveillance in control and elimination. PLoS Med. 2013;10:e1001467.
77. Perkins M, Bell D. Working without a blindfold: the critical role of diagnostics in malaria control. Malar J. 2008;7:S5.
78. Baniecki ML, Faust AL, Schaffner SF, Park DJ, Galinsky K, Daniels RF, et al. Development of a single nucleotide polymorphism barcode to genotype Plasmodium vivax infections. PLoS Negl Trop Dis. 2015;9:e0003539.
79. Karunaweera ND, Ferreira MU, Hartl DL, Wirth DF. Fourteen polymorphic microsatellite DNA markers for the human malaria parasite Plasmodium vivax. Mol Ecol Notes. 2007;7:172-5.
80. Lutz A. Waldmosquitos und Waldmalaria. Centralblatt für Bakteriologie, Parasitenkunde und Infektionskrankheiten. 1903;33:282-92.
81. Downs WG, Pittendrigh CS. Bromeliad malaria in Trinidad, British West Indies. Am J Trop Med Hyg. 1946;26:47-66.
82. Gadelha P. From, "forest malaria" to "bromeliad malaria": a case study of scientific controversy and malaria control. Parassitologia. 1994;36:175-95.
83. Rachou RG. Campaign against anophelines of the sub-genus Kerteszia in the south of Brazil. Rev Bras Malariol Doencas Trop. 1952;4:245-54 (in Portuguese).
84. Deane LM. Simian malaria in Brazil. Mem Inst Oswaldo Cruz. 1992;87:1-20.
85. Laporta G, Burattini M, Levy D, Fukuya L, de Oliveira T, Maselli L, et al. Plasmodium falciparum in the southeastern Atlantic forest: a challenge to the bromeliad-malaria paradigm? Malar J. 2015;14:181.
86. São Thiago PT. História da malária em Santa Catarina. Masteŕs thesis. Federal University of Santa Catarina, 2003.
87. Griffing SM, Tauil PL, Udhayakumar V, Silva-Flannery L. A historical perspective on malaria control in Brazil. Mem Inst Oswaldo Cruz. 2015;110:701-18.
88. Okell LC, Bousema T, Griffin JT, Ouédraogo AL, Ghani AC, et al. Factors determining the occurrence of submicroscopic malaria infections and their relevance for control. Nat Commun. 2012;3:1237.
89. WHO. Evidence review group on malaria diagnosis in low transmission setting. Meeting Report. Geneva: World Health Organization; 2014. p. 33.
90. Bomtempo JM. Memória sobre algumas enfermidades do Rio de Janeiro, e mui particularmente sobre o abuso geral, e pernicioso efeito da aplicação da preciosa casca Peruviana, ou quina. Rio de Janeiro: Typographia Nacional; 1825.
91. Neiva A. Formação de raça do hematozoario do impaludismo resistente a quinina. Mem Inst Oswaldo Cruz. 1910;2:131-40.
92. Couto M. Les injections endo-veineuses du bleu de méthylène dans le paludisme. Bull Soc Pathol Exot. 1908;1:292-5.
93. Benchimol JL, Silva AFC. Railroads, disease, and tropical medicine in Brazil under the First Republic. Hist Ciênc Saúde Manguinhos. 2008;15:719-62.
94. da Silva AFC, Benchimol JL. Malaria and quinine resistance: a medical and scientific issue between Brazil and Germany (1907-19). Med History. 2014;58:1-26.
95. Kremsner PG, Zotter GM, Feldmeier H, Graninger W, Kollaritsch M, Wiedermann G, et al. In vitro drug sensitivity of Plasmodium falciparum in Acre, Brazil. Bull World Health Organ. 1989;67:289-93.
96. Zalis MG, Pang L, Silveira MS, Milhous WK, Wirth DF. Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance. Am J Trop Med Hyg. 1998;58:630-7.
97. de Alencar FEC, Cerutti C, Durlacher RR, Boulos M, Alves FP, Milhous W, et al. Atovaquone and proguanil for the treatment of malaria in Brazil. J Infect Dis. 1997;175:1544-7.
98. Duarte EC, Fontes CJF, Gyorkos TW, Abrahamowicz M. Randomized controlled trial of artesunate plus tetracycline versus standard treatment (quinine plus tetracycline) for uncomplicated Plasmodium falciparum malaria in Brazil. Am J Trop Med Hyg. 1996;54:197-202.
99. de Souza JM. Epidemiological distribution of Plasmodium falciparum drug resistance in Brazil and its relevance to the treatment and control of malaria. Mem Inst Oswaldo Cruz. 1992;87:343-8.
100. Rodrigues DC. Casos de malária por Plasmodium falciparum resistentes ao tratamento pela cloroquina. Arquivos de Higiene e Saúde Pública. 1961;26:231-5.
101. Silva JR. Resistência do P. falciparum à ação da cloroquina. O Hospital. 1961;60:43-58.
102. Moore DV, Lanier JE. Observations on two Plasmodium falciparum infections with an abnormal response to chloroquine. Am J Trop Med Hyg. 1961;10:5-9.
103. Wootton JC, Feng X, Ferdig MT, Cooper RA, Mu J, Baruch DI, et al. Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. Nature. 2002;418:320-3.
104. Cortese JF, Caraballo A, Contreras CE, Plowe CV. Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America. J Infect Dis. 2002;186:999-1006.
105. Walker AJ, Lopez-Antunano FJ. Response to drugs of South American strains of Plasmodium falciparum. Trans R Soc Trop Med Hyg. 1968;62:654-67.
106. Almeida-Netto JC, Oliveira GSC, Sampaio JAA. Resistência do Plasmodium falciparum à associação sulfamidicos-antifólicos na Região Centro-Oeste do Brasil. Dados referentes ao estudo de 104 casos. Rev Patol Trop. 1972;1:385-93.
107. Suárez-Mutis MC, de Souza PP, Freitas LF, Miranda ES, Campos MR, Osorio-de-Castro CGS. Pharmaceutical services for endemic situations in the Brazilian Amazon: organization of services and prescribing practices for Plasmodium vivax and Plasmodium falciparum non-complicated malaria in high-risk municipalities. Malar J. 2011;10:335.
108. Noronha E, Alecrim MG, Romero GAS, Macêdo V. RIII mefloquine resistance in children with falciparum malaria in Manaus, AM, Brazil. Rev Soc Bras Med Trop. 2000;33:201-5.
109. Alencar FH, Ferraroni JJ, Shrimpton R. Resistência do Plasmodium falciparum ao Fansidar, quinina e tetraciclina. Rev Saude Publ. 1982;16:299-302.
110. Cerutti C, Durlacher RR, de Alencar FEC, Segurado AAC, Pang LW. In vivo efficacy of mefloquine for the treatment of falciparum malaria in Brazil. J Infect Dis. 1999;180:2077-80.
111. Souza JM. Mefloquine clinical trials - therapeutical experience with mefloquine alone and combination (MSP) in brazilian male subjects with falciparum malaria. Mem Inst Oswaldo Cruz. 1986;81:259-68.
112. Santelli A, Ribeiro I, Daher A, Boulos M, Marchesini P, dos Santos RL, et al. Effect of artesunate-mefloquine fixed-dose combination in malaria transmission in Amazon Basin communities. Malar J. 2012;11:286.
113. Ladeia-Andrade S, de Melo GN, de Souza-Lima RC, Salla LC, Bastos MS, Rodrigues PT, Luz FD, Ferreira MU. No clinical or molecular evidence of Plasmodium falciparum resistance to artesunate-mefloquine in northwestern Brazil. Am J Trop Med Hyg. 2016. doi: 10.4269/ajtmh.16-0017.
114. Adhin MR, Labadie-Bracho M, Vreden S. Gold mining areas in Suriname: reservoirs of malaria resistance? Infect Drug Resist. 2014;7:111-6.
115. Vreden SGS, Jitan JK, Bansie RD, Adhin MR. Evidence of an increased incidence of day 3 parasitaemia in Suriname: an indicator of the emerging resistance of Plasmodium falciparum to artemether. Mem Inst Oswaldo Cruz. 2013;108:968-73.
116. Nacher M, Guérin P, Demar-Pierre M, Djossou F, Nosten F, Carme B. Made in Europe: will artemisinin resistance emerge in French Guiana? Malar J. 2013;12:152.
117. Chenet SM, Akinyi Okoth S, Huber CS, Chandrabose J, Lucchi NW, Talundzic E, et al. Independent emergence of the Plasmodium falciparum kelch propeller domain mutant allele C580Y in Guyana. J Infect Dis. 2016;213:1472-5.
118. Price RN, von Seidlein L, Valecha N, Nosten F, Baird JK, White NJ. Global extent of chloroquine-resistant Plasmodium vivax: a systematic review and meta-analysis. Lancet Infect Dis. 2014;14:982-91.
119. Duarte EC, Pang LW, Ribeiro LC, Fontes CJ. Association of subtherapeutic dosages of a standard drug regimen with failures in preventing relapses of vivax malaria. Am J Trop Med Hyg. 2001;65:471-6.
120. Brasil. Guia prático de tratamento da malária no Brasil. Brasília: Ministério da Saúde, Secretaria de Vigilância em Saúde. Departamento de Vigilância Epidemiológica; 2010. p. 36.
121. Gonçalves LA, Cravo P, Ferreira MU. Emerging Plasmodium vivax resistance to chloroquine in South America: an overview. Mem Inst Oswaldo Cruz. 2014;109:534-9.
122. Phillips EJ, Keystone JS, Kain KC. Failure of combined chloroquine and high-dose primaquine therapy for Plasmodium vivax malaria acquired in Guyana, South America. Clin Infect Dis. 1996;23:1171-3.
123. Ruebush TK, Zegarra J, Cairo J, Andersen EM, Green M, Pillai DR, et al. Chloroquine-resistant Plasmodium vivax malaria in Peru. Am J Trop Med Hyg. 2003;69:548-52.
124. de Santana Filho FS, de Lima Arcanjo AR, Chehuan YM, Costa MR, Martinez-Espinosa FE, et al. Chloroquine-resistant Plasmodium vivax, Brazilian Amazon. Emerg Infect Dis. 2007;13:1125-6.
125. Marques MM, Costa MRF, Santana Filho FS, Vieira JLF, Nascimento MTS, Brasil LW, et al. Plasmodium vivax chloroquine resistance and anemia in the Western Brazilian Amazon. Antimicrob Agents Chemother. 2013;58:342-7.
126. Douglas NM, Anstey NM, Angus BJ, Nosten F, Price RN. Artemisinin combination therapy for vivax malaria. Lancet Infect Dis. 2010;10:405-16.
127. Egan TJ. Chloroquine and primaquine: combining old drugs as a new weapon against falciparum malaria? Trends Parasitol. 2006;22:235-7.
128. Naing C, Aung K, Win DK, Wah MJ. Efficacy and safety of chloroquine for treatment in patients with uncomplicated Plasmodium vivax infections in endemic countries. Trans R Soc Trop Med Hyg. 2010;104:695-705.
129. Baird K. Origins and implications of neglect of G6PD deficiency and primaquine toxicity in Plasmodium vivax malaria. Pathog Glob Health. 2015;109:93-106.
130. Monteiro WM, Val FFA, Siqueira AM, Franca GP, Sampaio VS, Melo GC, et al. G6PD deficiency in Latin America: systematic review on prevalence and variants. Mem Inst Oswaldo Cruz. 2014;109:553-68.
131. Nkhoma ET, Poole C, Vannappagari V, Hall SA, Beutler E. The global prevalence of glucose-6-phosphate dehydrogenase deficiency: a systematic review and meta-analysis. Blood Cells Mol Dis. 2009;42:267-78.
132. Monteiro W, Franca G, Melo G, Queiroz A, Brito M, Peixoto H, et al. Clinical complications of G6PD deficiency in Latin American and Caribbean populations: systematic review and implications for malaria elimination programmes. Malar J. 2014;13:70.
133. Boulos M, Amato Neto V, Dutra AP, Di Santi SM, Shiroma M. Frequency of malaria relapse due to Plasmodium vivax in a non-endemic region (Sao Paulo, Brazil). Rev Inst Med Trop Sao Paulo. 1991;33:143-6 (in Portuguese).
134. Reddy P, Flaherty JP. Plasmodium vivax malaria relapses after primaquine prophylaxis. Emerg Infect Dis. 2006;12:1795-6.
135. Nayar JK, Baker RH, Knight JW, Sullivan JS, Morris CL, Richardson BB, et al. Studies on a primaquine-tolerant strain of Plasmodium vivax from Brazil in Aotus and Saimiri monkeys. J Parasitol. 1997;83:739-45.
136. Hill DR, Baird JK, Parise ME, Lewis LS, Ryan ET, Magill AJ. Primaquine: report from CDC expert meeting on malaria chemoprophylaxis I. Am J Trop Med Hyg. 2006;75:402-15.
137. WHO. Guidelines for the treatment of malaria. 3rd ed. Geneva: World Health Organization; 2015. p. 316.
138. Llanos-Cuentas A, Lacerda MV, Rueangweerayut R, Krudsood S, Gupta SK, Kochar SK, et al. Tafenoquine plus chloroquine for the treatment and relapse prevention of Plasmodium vivax malaria (DETECTIVE): a multicentre, double-blind, randomised, phase 2b dose-selection study. Lancet. 2014;383:1049-58.
139. Desai M, ter Kuile FO, Nosten F, McGready R, Asamoa Kwame, Brabin PB, et al. Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis. 2007;7:93-104.
140. Macgregor JD, Avery JG. Malaria transmission and fetal growth. BMJ. 1974;3:433-6.
141. Marchesini P, Costa FTM, Marinho CRF. A decade of malaria during pregnancy in Brazil: what has been done concerning prevention and management. Mem Inst Oswaldo Cruz. 2014;109:706-8.
142. Mayor A, Moro L, Aguilar R, Bardají A, Cisteró P, Serra-Casas E, et al. How hidden can malaria be in pregnant women? Diagnosis by microscopy, placental histology, polymerase chain reaction and detection of histidine-rich protein 2 in plasma. Clin Infect Dis. 2012;54:1561-8.
143. Nosten F, McGready R, Simpson JA, Thwai KL, Balkan S, Cho T, et al. Effects of Plasmodium vivax malaria in pregnancy. Lancet. 1999;354:546-9.
144. McGready R, Davison BB, Stepniewska K, Cho T, Shee H, Brockman A, et al. The effects of Plasmodium falciparum and P. vivax infections on placental histopathology in an area of low malaria transmission. Am J Trop Med Hyg. 2004;70:398-407.
145. Souza RM, Ataíde R, Dombrowski JG, Ippólito V, Aitken EH, Valle SN, et al. Placental histopathological changes associated with Plasmodium vivax infection during pregnancy. PLoS Negl Trop Dis. 2013;7:e2071.
146. Machado Filho AC, da Costa EP, da Costa EP, Reis IS, Fernandes EAC, Paim BV, et al. Effects of vivax malaria acquired before 20 weeks of pregnancy on subsequent changes in fetal growth. Am J Trop Med Hyg. 2014;90:371-6.
147. Martínez-Espinosa FE, Daniel-Ribeiro CT, Alecrim WD. Malaria during pregnancy in a reference centre from the Brazilian Amazon: unexpected increase in the frequency of Plasmodium falciparum infections. Mem Inst Oswaldo Cruz. 2004;99:19-21.
148. Parekh FK, Hernandez JN, Krogstad DJ, Casapia WM, Branch OH. Prevalence and risk of Plasmodium falciparum and P. vivax malaria among pregnant women living in the hypoendemic communities of the Peruvian Amazon. Am J Trop Med Hyg. 2007;77:451-7.
149. WHO. Policy brief for the implementation of intermittent preventive treatment of malaria in pregnancy using sulfadoxine-pyrimethamine (IPTp-SP). Geneva: World Health Organization; 2013.
150. Maheu-Giroux M, Castro MC. Factors affecting providers' delivery of intermittent preventive treatment for malaria in pregnancy: a five-country analysis of national service provision assessment surveys. Malar J. 2014;13:440.
151. WHO. Evidence review group: intermittent preventive treatment of malaria in pregnancy (IPTp) with sulfadoxine-pyrimethamine (SP). Meeting report. Geneva: World Health Organization; 2012.
152. Serviço Especial de Saúde Pública. Adultos de anophelinos examinados pelo Laboratório Central e Divisão de Malária. Julho de 1942 - Junho de 1946. SESP - Programa da Amazônia. Casa de Oswaldo Cruz (FIOCRUZ) collection. LD/TP/19420740; 1946.
153. Deane LM. A chronological summary of the knowledge on the anophelines and their relation to malaria in the Amazon region of Brazil. Brasília: PAHO/WHO/TDR; 1988.
154. Elliott R. The influence of vector behavior on malaria transmission. Am J Trop Med Hyg. 1972;21:755-63.
155. Deane LM. Malaria vectors in Brazil. Mem Inst Oswaldo Cruz. 1986;81:5-14.
156. Rosa-Freitas MG, Broomfield G, Priestman A, Milligan PJM, Momen H, Molyneux DH. Cuticular hydrocarbons, isoenzymes and behavior of three populations of Anopheles darlingi from Brazil. J Am Mosquito Control Assoc. 1992;8:357-66.
157. Klein TA, Lima JBP. Seasonal distribution and biting patterns of Anopheles mosquitoes in Costa Marques, Rondônia, Brazil. J Am Mosquito Control Assoc. 1990;6:700-7.
158. Tadei WP. Considerações sobre as espécies de anopheles e a transmissão da malária na Amazônia. Manaus: INPA - Instituto Nacional de Pesquisas da Amazônia; 1991. p. 16.
159. Conn JE, Ribolla PE. Ecology of Anopheles darlingi, the primary malaria vector in the americas and current nongenetic methods of vector control. In: Adelman ZN, editor. Genetic Control of Malaria and Dengue. Oxford: Academic Press; 2015. p. 81-102.
160. Lengeler C. Insecticide-treated bed nets and curtains for preventing malaria. Cochrane Database Syst Rev. 2004;2:CD000363.
161. Alexander N, Rodríguez M, Pérez L, Caicedo JC, Cruz J, Prieto G, et al. Case-control study of mosquito nets against malaria in the Amazon Region of Colombia. Am J Trop Med Hyg. 2005;73:140-8.
162. Magris M, Rubio-Palis Y, Alexander N, Ruiz B, Galvan N, Frias D, et al. Community-randomized trial of lambdacyhalothrin-treated hammock nets for malaria control in Yanomami communities in the Amazon region of Venezuela. Trop Med Int Health. 2007;12:392-403.
163. Martins L. Uso de mosquiteiro especial reduz em 32 % casos de malária no Acre. In: Agencia Brasil. 2008. http://memoria.ebc.com.br/agenciabrasil/noticia/2008-02-18/uso-de-mosquiteiro-especial-reduz-em-32-casos-de-malaria-no-acre. Accessed 1 Dec 2015.
164. Brasil. Ministério da Saúde: Guia para Gestão Local do Controle da Malária. Módulo 2 - Controle Vetorial. In: Série B Normas e Manuais Técnicos. Brasília, DF: Ministério da Saúde. Secretaria de Vigilância em Saúde. Diretoria Técnica de Gestão; 2009. p. 59.
165. Ferreira FAS, Arcos AN, Sampaio RTM, Rodrigues IB, Tadei WP. Effect of Bacillus sphaericus Neide on Anopheles (Diptera: Culicidae) and associated insect fauna in fish ponds in the Amazon. Rev Bras Entomol. 2015;59:234-9.
166. WHO. World Malaria Report 2015. Geneva: World Health Organization; 2015. p. 243.
167. United Nations. OMS, Brasil e parceiro lançam plano de eliminação da malária no país. 2015. https://nacoesunidas.org/oms-brasil-e-parceiro-lancam-plano-de-eliminacao-da-malaria-no-pais/. Accessed 1 Nov 2015.
168. WHO. Strategy for malaria elimination in the greater Mekong subregion (2015-2030). Geneva: World Health Organization; 2015. p. 65.
169. Peixoto A. O problema sanitário da Amazônia. Rio de Janeiro; 1917. p. 28.
170. Lerer LB, Scudder T. Health impacts of large dams. Environ Impact Assess Rev. 1999;19:113-23.
171. Bauch SC, Birkenbach AM, Pattanayak SK, Sills EO. Public health impacts of ecosystem change in the Brazilian Amazon. Proc Natl Acad Sci USA. 2015;112:7414-9.
172. Fearnside PM. Environment: deforestation soars in the Amazon. Nature. 2015;521:423.
173. Brasil: Resolução CONAMA n. 286, de 30 de Agosto de 2001. Dispõe sobre o licenciamento ambiental de empreendimentos nas regiões endêmicas de malária. 2001.
174. Costello A, Abbas M, Allen A, Ball S, Bell S, Bellamy R, et al. Managing the health effects of climate change. Lancet. 2009;373:1693-733.
175. Watts N, Adger WN, Agnolucci P, Blackstock J, Byass P, Cai W, Chaytor S, et al. Health and climate change: policy responses to protect public health. Lancet. 2015;386:1861-914.
176. WHO. Protecting health from climate change: global research priorities. Geneva: World Health Organization; 2009.
177. Gething PW, Smith DL, Patil AP, Tatem AJ, Snow RW, Hay SI. Climate change and the global malaria recession. Nature. 2010;465:342-6.
178. Laneri K, Paul RE, Tall A, Faye J, Diene-Sarr F, Sokhna C, et al. Dynamical malaria models reveal how immunity buffers effect of climate variability. Proc Natl Acad Sci USA. 2015;112:8786-91.
179. Martens P, Kovats RS, Nijhof S, Vries Pd, Livermore MTJ, Bradley DJ, et al. Climate change and future populations at risk of malaria. Glob Environ Change. 1999;9:S89-107.
180. Pascual M, Ahumada JA, Chaves LF, Rodó X, Bouma M. Malaria resurgence in the East African highlands: temperature trends revisited. Proc Natl Acad Sci USA. 2006;103:5829-34.
181. Rogers DJ, Randolph SE. The global spread of malaria in a future, warmer world. Science. 2000;289:1763-6.
182. Yamana TK, Eltahir EAB. Projected impacts of climate change on environmental suitability for malaria transmission in West Africa. Environ Health Perspect. 2013;121:1179-86.
183. IPCC. IPCC 5th assessment report "Climate Change 2013: The Physical Science Basis". Final draft underlying scientific-technical assessment. Stockholm, 23-26 September 2013: Working Group I - 12th Session. 2013. http://www.ipcc.ch/report/ar5/wg1/#.UkveNn-gFTU. Accessed 1 Feb 2016.
184. Takken W, Vilarinhos PTR, Schneider P, Santos F. Effects of environmental change on malaria in the Amazon region of Brazil. In: Takken W, Martens P, Bogers R, editors. Environmental change and malaria risk: global and local implications. Wageningen; 2005. p. 113-23.
185. Paaijmans KP, Blanford S, Bell AS, Blanford JI, Read AF, Thomas MB. Influence of climate on malaria transmission depends on daily temperature variation. Proc Natl Acad Sci USA. 2010;107:15135-9.
186. Tambo E, Ai L, Zhou X, Chen J-H, Hu W, Bergquist R, Guo J-G, Utzinger J, Tanner M, Zhou X-N. Surveillance-response systems: the key to elimination of tropical diseases. Infect Dis Poverty. 2014;3:17.
187. Ohrt C, Roberts KW, Sturrock HJW, Wegbreit J, Lee BY, Gosling RD. Information systems to support surveillance for malaria elimination. Am J Trop Med Hyg. 2015;93:145-52.
188. Martens P, Hall L. Malaria on the move: human population movement and malaria transmission. Emerg Infect Dis. 2000;6:103-9.
189. Prothero RM. Forced movements of population and health hazards in tropical Africa. Int J Epidemiol. 1994;23:657-64.
190. Monte-Mór RL. Modernities in the jungle: extended urbanization in the Brazilian Amazonia. Ph.D., University of California, LA, USA. 2004.
191. Sturrock HJW, Roberts KW, Wegbreit J, Ohrt C, Gosling RD. Tackling imported malaria: an elimination endgame. Am J Trop Med Hyg. 2015;93:139-44.
192. Wangdi K, Gatton ML, Kelly GC, Clements ACA. Cross-border malaria: a major obstacle for malaria elimination. Adv Parasitol. 2015;89:79-107.
193. Pommier de Santi V, Dia A, Adde A, Hyvert G, Galant J, Mazevet M, et al. Malaria in French Guiana linked to illegal gold mining. Emerg Infect Dis. 2016;22:344-6.
194. United Nations. Transforming our world: the 2030 agenda for sustainable development. In: A/RES/70/1. Geneva: United Nations; 2015. p. 41.
195. United Nations Development Programme (UNDP). Multisectoral action framework for malaria. Geneva: United Nations Development Programme (UNDP), Roll Back Malaria Partnership (RBM); 2013. p. 68.
196. Brasil. Portaria no. 1, de 13 de Janeiro de 2014. Secretaria de Vigilância em Saúde. Diário Oficial da União - Seção 1. 2014. p. 4.
197. Cohen J, Smith D, Cotter C, Ward A, Yamey G, Sabot O, et al. Malaria resurgence: a systematic review and assessment of its causes. Malar J. 2012;11:122.
198. Koenker H, Keating J, Alilio M, Acosta A, Lynch M, Nafo-Traore F. Strategic roles for behaviour change communication in a changing malaria landscape. Malar J. 2014;13:1.
199. PAHO, WHO. Report on the status of malaria eradication in the Americas. XIV Report. Washington, DC: Pan American Health Organization, World Health Organization; 1966.