Comparing the functions of equine and canine influenza H3N8 virus PA-X proteins: Suppression of reporter gene expression and modulation of global host gene expression

Virology

Volumn 496, Issue , 2016, Pages 138-146

  Feng, Kurtis H ^a   Sun, Miao ^b   Iketani, Sho ^a   Holmes, Edward C ^c   Parrish, Colin R ^a  

^a Cornell University ^*  (United States)

^b GENOME INSTITUTE OF SINGAPORE   (Singapore)

^c University of Sydney   (Australia)

Author keywords

Canine H3N8; Equine H3N8; Gene suppression; Influenza; PA X; RNA seq

Indexed keywords

ASPARTIC ACID; PROTEIN PA X; SERINE; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA; PA-X PROTEIN, INFLUENZA A VIRUS; REPRESSOR PROTEIN; VIRAL PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DOG BREED; DOWN REGULATION; EQUIDAE; GENE EXPRESSION; GENE EXPRESSION MODULATION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE MUTATION; GENETIC DIFFERENCE; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HOST; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; INFLUENZA A VIRUS (H3N8); MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT; REPORTER GENE; RNA SEQUENCE; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS; STRAIN DIFFERENCE; UPREGULATION; VIRUS GENE; VIRUS STRAIN; ANIMAL; CELL LINE; CLUSTER ANALYSIS; DOG; GENE EXPRESSION PROFILING; GENETICS; HORSE; HOST PATHOGEN INTERACTION; METABOLISM; MUTATION; ORTHOMYXOVIRUS INFECTION; VIROLOGY;

ANIMALS; CELL LINE; CLUSTER ANALYSIS; DOGS; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES, REPORTER; HORSES; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLUENZA A VIRUS, H3N8 SUBTYPE; MUTATION; ORTHOMYXOVIRIDAE INFECTIONS; REPRESSOR PROTEINS; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84973869962     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2016.06.001     Document Type: Article

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