Polymer-iron oxide composite nanoparticles for EPR-independent drug delivery

Biomaterials

Volumn 101, Issue , 2016, Pages 285-295

  Park, Jinho ^a,b   Kadasala, Naveen Reddy ^c   Abouelmagd, Sara A ^a,d   Castanares, Mark A ^b   Collins, David S ^b   Wei, Alexander ^c   Yeo, Yoon ^a,e  

^a PURDUE UNIVERSITY   (United States)

^b ELI LILLY AND COMPANY   (United States)

^c PURDUE UNIVERSITY   (United States)

^d Assiut University   (Egypt)

^e PURDUE UNIVERSITY   (United States)

Author keywords

In vivo delivery; Magnetic drug delivery; Polydopamine; Polymer iron oxide nanocomposite; Polymeric nanoparticles

Indexed keywords

AMINES; CONTROLLED DRUG DELIVERY; FLUORESCENCE IMAGING; MAGNETIC FIELDS; MAGNETIC RESONANCE IMAGING; MAGNETITE; NANOCOMPOSITES; NANOMAGNETICS; NANOPARTICLES; TARGETED DRUG DELIVERY; TUMORS;

ENHANCED PERMEABILITY AND RETENTION EFFECTS; IN-VIVO; MAGNETIC DRUG DELIVERY; POLY LACTIC-CO-GLYCOLIC ACID; POLYDOPAMINE; POLYMERIC NANOPARTICLES; SURFACE MODIFICATION METHODS; THREE ORDERS OF MAGNITUDE;

IRON OXIDES;

DOPAMINE; MAGNETITE NANOPARTICLE; NANOCARRIER; NANOCOMPOSITE; POLYGLACTIN; POLYMER; POLYMER IRON OXIDE NANOCOMPOSITE; UNCLASSIFIED DRUG; DRUG CARRIER; INDOLE DERIVATIVE; LACTIC ACID; MAGNETITE; NANOPARTICLE; POLYDOPAMINE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

3T3 CELL LINE; ANIMAL CELL; ARTICLE; CELL VIABILITY; CONFOCAL MICROSCOPY; DISPERSION; DRUG ACCUMULATION; DRUG PENETRATION; DRUG RETENTION; ENHANCED PERMEABILITY AND RETENTION; EX VIVO STUDY; FLOW CYTOMETRY; FLUORESCENCE IMAGING; FLUORESCENCE MICROSCOPY; HISTOLOGY; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VIVO STUDY; MAGNETIC FIELD; MAGNETOTHERAPY; MOUSE; NANOPHARMACEUTICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OVARIAN CANCER CELL LINE; PARTICLE SIZE; PARTICULATE MATTER; PHOTON CORRELATION SPECTROSCOPY; POLYMERIZATION; PRIORITY JOURNAL; RETICULOENDOTHELIAL SYSTEM; STEADY STATE; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; TUMOR VOLUME; TUMOR XENOGRAFT; VENULE; XENOGRAFT; ZETA POTENTIAL; ANIMAL; CHEMISTRY; DIAGNOSTIC IMAGING; DRUG DELIVERY SYSTEM; MAGNETISM; NEOPLASM; NIH 3T3 CELL LINE; PROCEDURES; TUMOR CELL LINE; ULTRASTRUCTURE;

ANIMALS; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FERROSOFERRIC OXIDE; HUMANS; INDOLES; LACTIC ACID; MAGNETIC RESONANCE IMAGING; MAGNETICS; MICE; NANOPARTICLES; NEOPLASMS; NIH 3T3 CELLS; OPTICAL IMAGING; POLYGLYCOLIC ACID; POLYMERS;

EID: 84973862370     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.06.007     Document Type: Article

References (40)

1. Matsumura Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res. 1986, 46:6387-6392.
2. Maeda H., Nakamura H., Fang J. The EPR effect for macromolecular drug delivery to solid tumors: improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo. Adv. Drug Deliv. Rev. 2013, 65:71-79.
3. Davis M.E., Chen Z., Shin D.M. Nanoparticle therapeutics: an emerging treatment modality for cancer. Nat. Rev. Drug Discov. 2008, 7:771-782.
4. Peer D., Karp J.M., Hong S., Farokhzad O.C., Margalit R., Langer R. Nanocarriers as an emerging platform for cancer therapy. Nat. Nano 2007, 2:751-760.
5. Farokhzad O.C., Langer R. Impact of nanotechnology on drug delivery. ACS Nano 2009, 3:16-20.
6. Maeda H. Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity. Adv. Drug Deliv. Rev. 2015, 91:3-6.
7. Kunjachan S., Pola R., Gremse F., Theek B., Ehling J., Moeckel D., et al. Passive versus active tumor targeting using RGD- and NGR-modified polymeric nanomedicines. Nano Lett. 2014, 14:972-981.
8. Nichols J.W., Bae Y.H. EPR: evidence and fallacy. J. Control. Release 2014, 190:451-464.
9. Bertrand N., Wu J., Xu X., Kamaly N., Farokhzad O.C. Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology. Adv. Drug Deliv. Rev. 2014, 66:2-25.
10. Prabhakar U., Maeda H., Jain R.K., Sevick-Muraca E.M., Zamboni W., Farokhzad O.C., et al. Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology. Cancer Res. 2013, 73:2412-2417.
11. Smith B.R., Kempen P., Bouley D., Xu A., Liu Z., Melosh N., et al. Shape matters: intravital microscopy reveals surprising geometrical dependence for nanoparticles in tumor models of extravasation. Nano Lett. 2012, 12:3369-3377.
12. Shi C., Guo D., Xiao K., Wang X., Wang L., Luo J. A drug-specific nanocarrier design for efficient anticancer therapy. Nat. Commun. 2015, 6:7449.
13. Lubbe A.S., Alexiou C., Bergemann C. Clinical applications of magnetic drug targeting. J. Surg. Res. 2001, 95:200-206.
14. Alexiou C., Jurgons R. Magnetic Drug Targeting. Magnetism in Medicine 2007, 596-605. Wiley-VCH Verlag GmbH & Co. KGaA.
15. Shapiro B., Kulkarni S., Nacev A., Muro S., Stepanov P.Y., Weinberg I.N. Open challenges in magnetic drug targeting. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol 2015, 7:446-457.
16. Hua M.Y., Yang H.W., Liu H.L., Tsai R.Y., Pang S.T., Chuang K.L., et al. Superhigh-magnetization nanocarrier as a doxorubicin delivery platform for magnetic targeting therapy. Biomaterials 2011, 32:8999-9010.
17. Alexiou C., Schmid R.J., Jurgons R., Kremer M., Wanner G., Bergemann C., et al. Targeting cancer cells: magnetic nanoparticles as drug carriers. Eur. Biophys. J. 2006, 35:446-450.
18. Hua M.Y., Liu H.L., Yang H.W., Chen P.Y., Tsai R.Y., Huang C.Y., et al. The effectiveness of a magnetic nanoparticle-based delivery system for BCNU in the treatment of gliomas. Biomaterials 2011, 32:516-527.
19. Nobuto H., Sugita T., Kubo T., Shimose S., Yasunaga Y., Murakami T., et al. Evaluation of systemic chemotherapy with magnetic liposomal doxorubicin and a dipole external electromagnet. Int. J. Cancer 2004, 109:627-635.
20. Fortin-Ripoche J.P., Martina M.S., Gazeau F., Menager C., Wilhelm C., Bacri J.C., et al. Magnetic targeting of magnetoliposomes to solid tumors with MR imaging monitoring in mice: feasibility. Radiology 2006, 239:415-424.
21. Lubbe A.S., Bergemann C., Riess H., Schriever F., Reichardt P., Possinger K., et al. Clinical experiences with magnetic drug targeting: a phase I study with 4'-epidoxorubicin in 14 patients with advanced solid tumors. Cancer Res. 1996, 56:4686-4693.
22. Xu P., Gullotti E., Tong L., Highley C.B., Errabelli D.R., Hasan T., et al. Intracellular drug delivery by poly(lactic-co-glycolic acid) nanoparticles, revisited. Mol. Pharm. 2009, 6:190-201.
23. Abouelmagd S.A., Sun B., Chang A.C., Ku Y.J., Yeo Y. Release kinetics study of poorly water-soluble drugs from nanoparticles: are we doing it right?. Mol. Pharm. 2015, 12:997-1003.
24. Elbialy N.S., Fathy M.M., Khalil W.M. Doxorubicin loaded magnetic gold nanoparticles for in vivo targeted drug delivery. Int. J. Pharm. 2015, 490:190-199.
25. Hafeli U.O., Riffle J.S., Harris-Shekhawat L., Carmichael-Baranauskas A., Mark F., Dailey J.P., et al. Cell uptake and in vitro toxicity of magnetic nanoparticles suitable for drug delivery. Mol. Pharm. 2009, 6:1417-1428.
26. Lee H., Dellatore S.M., Miller W.M., Messersmith P.B. Mussel-inspired surface chemistry for multifunctional coatings. Science 2007, 318:426-430.
27. Park J., Brust T.F., Lee H.J., Lee S.C., Watts V.J., Yeo Y. Polydopamine-based simple and versatile surface modification of polymeric nano drug carriers. ACS Nano 2014, 8:3347-3356.
28. Massart R., Cabuil V. Synthesis of colloidal magnetite in alkaline medium: yield and particle size control. J. de Chimie Physique 1987, 84:967-973.
29. Chen H., Kim S., Li L., Wang S., Park K., Cheng J.-X. Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Forster resonance energy transfer imaging. Proc. Natl. Acad. Sci. U. S. A. 2008, 105:6596-6601.
30. Chen H., Kim S., He W., Wang H., Low P.S., Park K., et al. Fast release of lipophilic agents from circulating PEG-PDLLA micelles revealed by in vivo forster resonance energy transfer imaging. Langmuir 2008, 24:5213-5217.
31. Hobbs S.K., Monsky W.L., Yuan F., Roberts W.G., Griffith L., Torchilin V.P., et al. Regulation of transport pathways in tumor vessels: role of tumor type and microenvironment. Proc. Natl. Acad. Sci. U. S. A. 1998, 95:4607-4612.
32. Miles F.L., Pruitt F.L., van Golen K.L., Cooper C.R. Stepping out of the flow: capillary extravasation in cancer metastasis. Clin. Exp. Metastasis 2008, 25:305-324.
33. Marieb E.N., Hoehn K. The Cardiovascular System: Blood Vessels, Human Anatomy & Physiology 2013, 712. Pearson Education, Inc. ninth ed.
34. Smith B.R., Cheng Z., De A., Koh A.L., Sinclair R., Gambhir S.S. Real-time intravital imaging of RGD-quantum dot binding to luminal endothelium in mouse tumor neovasculature. Nano Lett. 2008, 8:2599-2606.
35. Kong G., Braun R.D., Dewhirst M.W. Hyperthermia enables tumor-specific nanoparticle delivery: effect of particle size. Cancer Res. 2000, 60:4440-4445.
36. Shapiro B., Kulkarni S., Nacev A., Sarwar A., Preciado D., Depireux D.A. Shaping magnetic fields to direct therapy to ears and eyes. Annu. Rev. Biomed. Eng. 2014, 16:455-481.
37. Sarwar A., Nemirovski A., Shapiro B. Optimal Halbach permanent magnet designs for maximally pulling and pushing nanoparticles. J. Magn. Magn. Mater 2012, 324:742-754.
38. Phillips E.H., Yrineo A.A., Schroeder H.D., Wilson K.W., Cheng J.X., Goergen C.J. Morphological and biomechanical differences in the elastase and AngII apoE (-/-) rodent models of abdominal aortic aneurysms. Biomed. Res. Int. 2015, 2015:413189.
39. Xia J., Yao J., Wang L.V. Photoacoustic tomography: principles and advances. Electromagn. waves Camb. Mass) 2014, 147:1-22.
40. Wang T., Brewer M., Zhu Q. An overview of optical coherence tomography for ovarian tissue imaging and characterization. Wiley Interdiscip. Rev. Nanomedicine Nanobiotechnology 2015, 7:1-16.