메뉴 건너뛰기




Volumn 14, Issue 1, 2016, Pages

Q & A: What are exosomes, exactly?

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER;

EID: 84973659689     PISSN: None     EISSN: 17417007     Source Type: Journal    
DOI: 10.1186/s12915-016-0268-z     Document Type: Article
Times cited : (275)

References (38)
  • 1
    • 0020804037 scopus 로고
    • Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes
    • Harding C, Heuser J, Stahl P. Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes. J Cell Biol. 1983;97(2):329-39.
    • (1983) J Cell Biol , vol.97 , Issue.2 , pp. 329-339
    • Harding, C.1    Heuser, J.2    Stahl, P.3
  • 2
    • 0022201056 scopus 로고
    • Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes
    • Pan BT, Teng K, Wu C, Adam M, Johnstone RM. Electron microscopic evidence for externalization of the transferrin receptor in vesicular form in sheep reticulocytes. J Cell Biol. 1985;101(3):942-8.
    • (1985) J Cell Biol , vol.101 , Issue.3 , pp. 942-948
    • Pan, B.T.1    Teng, K.2    Wu, C.3    Adam, M.4    Johnstone, R.M.5
  • 3
    • 0023645106 scopus 로고
    • Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes)
    • Johnstone RM, Adam M, Hammond JR, Orr L, Turbide C. Vesicle formation during reticulocyte maturation. Association of plasma membrane activities with released vesicles (exosomes). J Biol Chem. 1987;262(19):9412-20.
    • (1987) J Biol Chem , vol.262 , Issue.19 , pp. 9412-9420
    • Johnstone, R.M.1    Adam, M.2    Hammond, J.R.3    Orr, L.4    Turbide, C.5
  • 5
    • 0031863853 scopus 로고    scopus 로고
    • Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes
    • Zitvogel L, Regnault A, Lozier A, Wolfers J, Flament C, Tenza D, et al. Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes. Nat Med. 1998;4(5):594-600.
    • (1998) Nat Med , vol.4 , Issue.5 , pp. 594-600
    • Zitvogel, L.1    Regnault, A.2    Lozier, A.3    Wolfers, J.4    Flament, C.5    Tenza, D.6
  • 6
    • 84959440540 scopus 로고    scopus 로고
    • Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells
    • Kim MS, Haney MJ, Zhao Y, Mahajan V, Deygen I, Klyachko NL, et al. Development of exosome-encapsulated paclitaxel to overcome MDR in cancer cells. Nanomedicine. 2015;12(3):655-64.
    • (2015) Nanomedicine , vol.12 , Issue.3 , pp. 655-664
    • Kim, M.S.1    Haney, M.J.2    Zhao, Y.3    Mahajan, V.4    Deygen, I.5    Klyachko, N.L.6
  • 7
    • 69449086077 scopus 로고    scopus 로고
    • No strings attached: the ESCRT machinery in viral budding and cytokinesis
    • McDonald B, Martin-Serrano J. No strings attached: the ESCRT machinery in viral budding and cytokinesis. J Cell Sci. 2009;122(Pt 13):2167-77.
    • (2009) J Cell Sci , vol.122 , pp. 2167-2177
    • McDonald, B.1    Martin-Serrano, J.2
  • 8
    • 67249110996 scopus 로고    scopus 로고
    • Multivesicular endosome biogenesis in the absence of ESCRTs
    • Stuffers S, Sem Wegner C, Stenmark H, Brech A. Multivesicular endosome biogenesis in the absence of ESCRTs. Traffic. 2009;10(7):925-37.
    • (2009) Traffic , vol.10 , Issue.7 , pp. 925-937
    • Stuffers, S.1    Sem Wegner, C.2    Stenmark, H.3    Brech, A.4
  • 9
    • 84892496851 scopus 로고    scopus 로고
    • Hrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesicles
    • Edgar JR, Eden ER, Futter CE. Hrs- and CD63-dependent competing mechanisms make different sized endosomal intraluminal vesicles. Traffic. 2014;15(2):197-211.
    • (2014) Traffic , vol.15 , Issue.2 , pp. 197-211
    • Edgar, J.R.1    Eden, E.R.2    Futter, C.E.3
  • 10
    • 40049112564 scopus 로고    scopus 로고
    • Ceramide triggers budding of exosome vesicles into multivesicular endosomes
    • Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F, et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science. 2008;319(5867):1244-7.
    • (2008) Science , vol.319 , Issue.5867 , pp. 1244-1247
    • Trajkovic, K.1    Hsu, C.2    Chiantia, S.3    Rajendran, L.4    Wenzel, D.5    Wieland, F.6
  • 11
    • 30444456831 scopus 로고    scopus 로고
    • EGF stimulates annexin 1-dependent inward vesiculation in a multivesicular endosome subpopulation
    • White IJ, Bailey LM, Aghakhani MR, Moss SE, Futter CE. EGF stimulates annexin 1-dependent inward vesiculation in a multivesicular endosome subpopulation. EMBO J. 2006;25(1):1-12.
    • (2006) EMBO J , vol.25 , Issue.1 , pp. 1-12
    • White, I.J.1    Bailey, L.M.2    Aghakhani, M.R.3    Moss, S.E.4    Futter, C.E.5
  • 12
    • 0036144685 scopus 로고    scopus 로고
    • Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O
    • Mobius W, Ohno-Iwashita Y, van Donselaar EG, Oorschot VM, Shimada Y, Fujimoto T, et al. Immunoelectron microscopic localization of cholesterol using biotinylated and non-cytolytic perfringolysin O. J Histochem Cytochem. 2002;50(1):43-55.
    • (2002) J Histochem Cytochem , vol.50 , Issue.1 , pp. 43-55
    • Mobius, W.1    Ohno-Iwashita, Y.2    Donselaar, E.G.3    Oorschot, V.M.4    Shimada, Y.5    Fujimoto, T.6
  • 13
    • 69249223795 scopus 로고    scopus 로고
    • MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways
    • Buschow SI, Nolte-'t Hoen EN, van Niel G, Pols MS, ten Broeke T, Lauwen M, et al. MHC II in dendritic cells is targeted to lysosomes or T cell-induced exosomes via distinct multivesicular body pathways. Traffic. 2009;10(10):1528-42.
    • (2009) Traffic , vol.10 , Issue.10 , pp. 1528-1542
    • Buschow, S.I.1    Nolte-'t Hoen, E.N.2    Niel, G.3    Pols, M.S.4    Broeke, T.5    Lauwen, M.6
  • 14
    • 0036533633 scopus 로고    scopus 로고
    • TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex
    • Blanchard N, Lankar D, Faure F, Regnault A, Dumont C, Raposo G, et al. TCR activation of human T cells induces the production of exosomes bearing the TCR/CD3/zeta complex. J Immunol. 2002;168(7):3235-41.
    • (2002) J Immunol , vol.168 , Issue.7 , pp. 3235-3241
    • Blanchard, N.1    Lankar, D.2    Faure, F.3    Regnault, A.4    Dumont, C.5    Raposo, G.6
  • 15
    • 34948874323 scopus 로고    scopus 로고
    • T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes
    • Muntasell A, Berger AC, Roche PA. T cell-induced secretion of MHC class II-peptide complexes on B cell exosomes. EMBO J. 2007;26(19):4263-72.
    • (2007) EMBO J , vol.26 , Issue.19 , pp. 4263-4272
    • Muntasell, A.1    Berger, A.C.2    Roche, P.A.3
  • 16
    • 0037490207 scopus 로고    scopus 로고
    • Exosome release is regulated by a calcium-dependent mechanism in K562 cells
    • Savina A, Furlan M, Vidal M, Colombo MI. Exosome release is regulated by a calcium-dependent mechanism in K562 cells. J Biol Chem. 2003;278(22):20083-90.
    • (2003) J Biol Chem , vol.278 , Issue.22 , pp. 20083-20090
    • Savina, A.1    Furlan, M.2    Vidal, M.3    Colombo, M.I.4
  • 17
    • 84964665924 scopus 로고    scopus 로고
    • Stimulating the release of exosomes increases the intercellular transfer of prions
    • Guo BB, Bellingham SA, Hill AF. Stimulating the release of exosomes increases the intercellular transfer of prions. J Biol Chem. 2016;291(10):5128-37.
    • (2016) J Biol Chem , vol.291 , Issue.10 , pp. 5128-5137
    • Guo, B.B.1    Bellingham, S.A.2    Hill, A.F.3
  • 18
    • 0034254524 scopus 로고    scopus 로고
    • Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface
    • Denzer K, van Eijk M, Kleijmeer MJ, Jakobson E, de Groot C, Geuze HJ. Follicular dendritic cells carry MHC class II-expressing microvesicles at their surface. J Immunol. 2000;165(3):1259-65.
    • (2000) J Immunol , vol.165 , Issue.3 , pp. 1259-1265
    • Denzer, K.1    Eijk, M.2    Kleijmeer, M.J.3    Jakobson, E.4    Groot, C.5    Geuze, H.J.6
  • 19
    • 84890875112 scopus 로고    scopus 로고
    • ALIX and the multivesicular endosome: ALIX in Wonderland
    • Bissig C, Gruenberg J. ALIX and the multivesicular endosome: ALIX in Wonderland. Trends Cell Biol. 2014;24(1):19-25.
    • (2014) Trends Cell Biol , vol.24 , Issue.1 , pp. 19-25
    • Bissig, C.1    Gruenberg, J.2
  • 20
    • 4444224022 scopus 로고    scopus 로고
    • Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway
    • Abrami L, Lindsay M, Parton RG, Leppla SH, van der Goot FG. Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathway. J Cell Biol. 2004;166(5):645-51.
    • (2004) J Cell Biol , vol.166 , Issue.5 , pp. 645-651
    • Abrami, L.1    Lindsay, M.2    Parton, R.G.3    Leppla, S.H.4    Goot, F.G.5
  • 22
    • 34249302620 scopus 로고    scopus 로고
    • Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
    • Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO. Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol. 2007;9(6):654-9.
    • (2007) Nat Cell Biol , vol.9 , Issue.6 , pp. 654-659
    • Valadi, H.1    Ekstrom, K.2    Bossios, A.3    Sjostrand, M.4    Lee, J.J.5    Lotvall, J.O.6
  • 23
    • 84911966357 scopus 로고    scopus 로고
    • Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis
    • Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, et al. Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell. 2014;26(5):707-21.
    • (2014) Cancer Cell , vol.26 , Issue.5 , pp. 707-721
    • Melo, S.A.1    Sugimoto, H.2    O'Connell, J.T.3    Kato, N.4    Villanueva, A.5    Vidal, A.6
  • 25
    • 84856707794 scopus 로고    scopus 로고
    • Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease
    • Saman S, Kim W, Raya M, Visnick Y, Miro S, Saman S, et al. Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease. J Biol Chem. 2012;287(6):3842-9.
    • (2012) J Biol Chem , vol.287 , Issue.6 , pp. 3842-3849
    • Saman, S.1    Kim, W.2    Raya, M.3    Visnick, Y.4    Miro, S.5    Saman, S.6
  • 27
    • 77952648551 scopus 로고    scopus 로고
    • Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival
    • Emmanouilidou E, Melachroinou K, Roumeliotis T, Garbis SD, Ntzouni M, Margaritis LH, et al. Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival. J Neurosci. 2010;30(20):6838-51.
    • (2010) J Neurosci , vol.30 , Issue.20 , pp. 6838-6851
    • Emmanouilidou, E.1    Melachroinou, K.2    Roumeliotis, T.3    Garbis, S.D.4    Ntzouni, M.5    Margaritis, L.H.6
  • 28
    • 35448956015 scopus 로고    scopus 로고
    • Evidence for secretion of Cu, Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis
    • Gomes C, Keller S, Altevogt P, Costa J. Evidence for secretion of Cu, Zn superoxide dismutase via exosomes from a cell model of amyotrophic lateral sclerosis. Neurosci Lett. 2007;428(1):43-6.
    • (2007) Neurosci Lett , vol.428 , Issue.1 , pp. 43-46
    • Gomes, C.1    Keller, S.2    Altevogt, P.3    Costa, J.4
  • 29
    • 84864411871 scopus 로고    scopus 로고
    • Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types
    • Guduric-Fuchs J, O'Connor A, Camp B, O'Neill CL, Medina RJ, Simpson DA. Selective extracellular vesicle-mediated export of an overlapping set of microRNAs from multiple cell types. BMC Genomics. 2012;13:357.
    • (2012) BMC Genomics , vol.13 , pp. 357
    • Guduric-Fuchs, J.1    O'Connor, A.2    Camp, B.3    O'Neill, C.L.4    Medina, R.J.5    Simpson, D.A.6
  • 30
    • 84937942782 scopus 로고    scopus 로고
    • ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-beta accumulation
    • Edgar JR, Willen K, Gouras GK, Futter CE. ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-beta accumulation. J Cell Sci. 2015;128(14):2520-8.
    • (2015) J Cell Sci , vol.128 , Issue.14 , pp. 2520-2528
    • Edgar, J.R.1    Willen, K.2    Gouras, G.K.3    Futter, C.E.4
  • 32
    • 84861866572 scopus 로고    scopus 로고
    • The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC
    • Fabian MR, Sonenberg N. The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC. Nat Struct Mol Biol. 2012;19(6):586-93.
    • (2012) Nat Struct Mol Biol , vol.19 , Issue.6 , pp. 586-593
    • Fabian, M.R.1    Sonenberg, N.2
  • 33
    • 85008708017 scopus 로고    scopus 로고
    • Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation
    • Bobrie A, Colombo M, Krumeich S, Raposo G, Thery C. Diverse subpopulations of vesicles secreted by different intracellular mechanisms are present in exosome preparations obtained by differential ultracentrifugation. J Extracell Vesicles. 2012;1:18397.
    • (2012) J Extracell Vesicles , vol.1 , pp. 18397
    • Bobrie, A.1    Colombo, M.2    Krumeich, S.3    Raposo, G.4    Thery, C.5
  • 34
    • 0035877018 scopus 로고    scopus 로고
    • Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles
    • Thery C, Boussac M, Veron P, Ricciardi-Castagnoli P, Raposo G, Garin J, et al. Proteomic analysis of dendritic cell-derived exosomes: a secreted subcellular compartment distinct from apoptotic vesicles. J Immunol. 2001;166(12):7309-18.
    • (2001) J Immunol , vol.166 , Issue.12 , pp. 7309-7318
    • Thery, C.1    Boussac, M.2    Veron, P.3    Ricciardi-Castagnoli, P.4    Raposo, G.5    Garin, J.6    Amigorena, S.7
  • 35
  • 36
    • 84973605178 scopus 로고    scopus 로고
    • ExoCarta
    • ExoCarta. http://www.exocarta.org.
  • 37
    • 43249109372 scopus 로고    scopus 로고
    • Isolation and characterization of exosomes from cell culture supernatants and biological fluids
    • Chapter 3:Unit 3 22
    • Thery C, Amigorena S, Raposo G, Clayton A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Curr Protocols Cell Biol. 2006;Chapter 3:Unit 3 22.
    • (2006) Curr Protocols Cell Biol.
    • Thery, C.1    Amigorena, S.2    Raposo, G.3    Clayton, A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.