ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-β accumulation

Journal of Cell Science

Volumn 128, Issue 14, 2015, Pages 2520-2528

  Edgar, James R ^a,b   Willén, Katarina ^c   Gouras, Gunnar K ^c   Futter, Clare E ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c LUND UNIVERSITY   (Sweden)

Author keywords

Alzheimer's disease; Amyloid precursor protein; ESCRT; multivesicular body

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; ESCRT PROTEIN; APP PROTEIN, HUMAN; EGFR PROTEIN, HUMAN;

ANIMAL TISSUE; ARTICLE; CELL VACUOLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; INTRACELLULAR SPACE; INTRALUMINAL VESICLE; LYSOSOME; MOUSE; MULTIVESICULAR BODY; NONHUMAN; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN TARGETING; PROTEIN TRANSPORT; REGULATORY MECHANISM; ALZHEIMER DISEASE; ENDOSOME; GENETICS; METABOLISM; PATHOLOGY; TUMOR CELL LINE; ULTRASTRUCTURE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; CELL LINE, TUMOR; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; ENDOSOMES; HUMANS; LYSOSOMES; RECEPTOR, EPIDERMAL GROWTH FACTOR;

EID: 84937942782     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.170233     Document Type: Article

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