Reliable detection of mismatch repair deficiency in colorectal cancers using mutational load in next-generation sequencing panels

Journal of Clinical Oncology

Volumn 34, Issue 18, 2016, Pages 2141-2147

  Stadler, Zsofia K ^a   Battaglin, Francesca ^a,b   Middha, Sumit ^a   Hechtman, Jaclyn F ^a   Tran, Christina ^a   Cercek, Andrea ^a   Yaeger, Rona ^a   Segal, Neil H ^a   Varghese, Anna M ^a   Reidy Lagunes, Diane L ^a   Kemeny, Nancy E ^a   Salo Mullen, Erin E ^a   Ashraf, Asad ^a   Weiser, Martin R ^a   Garcia Aguilar, Julio ^a   Robson, Mark E ^a   Offit, Kenneth ^a   Arcila, Maria E ^a   Berger, Michael F ^a   Shia, Jinru ^a   Solit, David B ^a   Saltz, Leonard B ^a   more..

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b VENETO INSTITUTE OF ONCOLOGY IOV IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MISMATCH REPAIR PROTEIN;

ADULT; AGED; ARTICLE; ASSAY; COLORECTAL CANCER; GENE MUTATION; GENOMICS; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MIDDLE AGED; MISMATCH REPAIR; MUTATIONAL LOAD; NEXT GENERATION SEQUENCING; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SENSITIVITY AND SPECIFICITY; WILD TYPE; YOUNG ADULT; ADOLESCENT; BRAIN NEOPLASMS; COLORECTAL NEOPLASMS; GENETICS; HIGH THROUGHPUT SEQUENCING; MUTATION; NEOPLASTIC SYNDROMES, HEREDITARY; PROCEDURES;

ADOLESCENT; ADULT; AGED; BRAIN NEOPLASMS; COLORECTAL NEOPLASMS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MIDDLE AGED; MUTATION; NEOPLASTIC SYNDROMES, HEREDITARY;

EID: 84973622902     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2015.65.1067     Document Type: Article

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