Quality control and complication screening programme of Chinese medicinal drugs at the first German hospital of traditional Chinese medicine - A retrospective analysis

Forschende Komplementarmedizin

Volumn 23, Issue 2, 2016, Pages 21-28

  Melchart, Dieter ^a,b   Hager, Stefan ^c   Dai, Jingzhang ^c,d   Weidenhammer, Wolfgang ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c TCM Hospital Bad Kötzting   (Germany)

^d BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Chinese medicinal drugs; Elevated liver enzyme; Hepatotoxicity; Herb induced liver injury; Quality control; Screening programme; Traditional Chinese Medicine

Indexed keywords

HERBACEOUS AGENT;

CHINESE MEDICINE; DRUG CONTAMINATION; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; GERMANY; HOSPITAL; HUMAN; MASS SCREENING; PRECLINICAL STUDY; PREVENTION AND CONTROL; QUALITY CONTROL; STANDARDS;

DRUG CONTAMINATION; DRUG EVALUATION, PRECLINICAL; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; DRUGS, CHINESE HERBAL; GERMANY; HOSPITALS; HUMANS; MASS SCREENING; MEDICINE, CHINESE TRADITIONAL; QUALITY CONTROL;

EID: 84973517575     PISSN: 16614119     EISSN: 16614127     Source Type: Journal    
DOI: 10.1159/000444983     Document Type: Article

References (18)

1. Eardley S, Bishop FL, Prescott P, et al.: A systematic literature review of complementary and alternative medicine prevalence in EU. Forsch Komplementmed 2012; 19 (suppl 2): 18-28.
2. Rossi S, Navarro VJ: Herbs and liver injury: a clinical perspective. Clin Gastroenterol Hepatol 2014; 12: 1069-1076.
3. Teschke R, Zhang L, Long H, Schwarzenboeck A, Schmidt-Taenzer W, Genthner A, Wolff A, Frenzel C, Schulze J, Eickhoff A: Traditional Chinese Medicine and herbal hepatotoxicity: a tabular compilation of reported cases. Ann Hepatol 2015; 14: 7-19.
4. Woo HJ, Kim HY, Choi ES, Cho YH, Kim Y, Lee JH, Jang E: Drug-induced liver injury: A 2-year retrospective study of 1, 169 hospitalized patients in a single medical center. Phytomedicine 2015; 22;:1201-1205.
5. Daǧ MS, Aydinli M, Oztürk ZA, Türkbeyler IH, Koruk I, Savaş MC, Koruk M, Kadayifçi A: Drug- and herb-induced liver injury: a case series from a single center. Turk J Gastroenterol 2014; 25: 41-45.
6. Zhao P, Wang C, Liu W, Wang F: Acute liver failure associated with traditional Chinese medicine: report of 30 cases from seven tertiary hospitals in China. Crit Care Med 2014; 42:e296-299.
7. Björnsson ES: Drug-induced liver injury: an overview over the most critical compounds. Arch Toxicol 2015; 89: 327-334.
8. Izzo AA, Ernst E: Interactions between herbal medicines and prescribed drugs: an updated systematic review. Drugs 2009; 69: 1777-1798.
9. Melchart D, Linde K, Hager S, Kaesmar J, Shaw D, Bauer R, Weidenhammer W: Monitoring of liver enzymes in patients treated with traditional Chinese drugs. Complement Ther Med 1999; 7: 208-216.
10. Melchart D, Weidenhammer W, Hager S, Shaw D, Bauer R: Liver enzyme elevations in patients treated with traditional Chinese medicine. JAMA 1999; 282: 28-29.
11. Teschke R, Wolff A, Frenzel C, Schwarzenboeck A, Schulze J, Eickhoff A: Drug and herb induced liver injury: Council for International Organizations of Medical Sciences scale for causality assessment. World J Hepatol 2014; 27: 17-32.
12. Abdualmjid RJ, Sergi C: Hepatotoxic botanicals - an evidence-based systematic review. J Pharm Pharmaceut Sci 2013; 16: 376-404.
13. Buchornatavakul C, Reddy KR: Review article: herbal and dietary supplement hepatotoxicity. Aliment Pharmacol Ther 2013; 37: 3-17.
14. Fasinu PS, Bouic PJ, Rosenkranz B: An overview of the evidence and mechanisms of herb-drug interactions. Front Pharmacol 2012; 30: 69.
15. Björnsson ES, Bergmann OM, Björnsson HK, Kvaran RB, Olafsson S: Incidence, presentation, and outcomes in patients with drug-induced liver injury in the general population of Iceland. Gastroenterology 2013; 144: 1419-1425.
16. LiverTox. Clinical and research information on drug-induced liver injury. herbals and dietary supplements. www.livertox.nih.gov/Herbals-and-Dietary-Supplements.htm (accessed February 26, 2016).
17. Melchart D, Hager S, Weidenhammer W, Liao JZ, Söllner C, Linde K: Tolerance of and compliance with traditional drug therapy among patients in a hospital for Chinese medicine in Germany. Int J Risk Safety Med 1998; 11: 61-64.
18. Posadzki P, Watson L, Ernst E: Contamination and adulteration of herbal medicinal products (HMPs): an overview of systematic reviews. Eur J Clin Pharmacol 2013; 69: 295-307.