Development of near-infrared photoactivable phthalocyanine-loaded nanoparticles to kill tumor cells: An improved tool for photodynamic therapy of solid cancers

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 12, Issue 7, 2016, Pages 1885-1897

  Duchi, Serena ^a,b   Ramos Romero, Sara ^c,d   Dozza, Barbara ^a,b   Guerra Rebollo, Marta ^c,d   Cattini, Luca ^a   Ballestri, Marco ^e   Dambruoso, Paolo ^e   Guerrini, Andrea ^e   Sotgiu, Giovanna ^e   Varchi, Greta ^e   Lucarelli, Enrico ^a,b   Blanco, Jeronimo ^c,d  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^d BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

^e CNR   (Italy)

Author keywords

Bioluminescence imaging; Nanoparticles; Photodynamic therapy; Prostate cancer; Solid tumors; Tetrasulfonated aluminum phthalocyanine

Indexed keywords

CELL DEATH; DISEASES; INFRARED DEVICES; IRRADIATION; LIGHT; MAMMALS; NANOPARTICLES; PHOTOSENSITIZERS; TUMORS; UROLOGY;

ALUMINUM PHTHALOCYANINE; BIOLUMINESCENCE IMAGING; FLUORESCENT NANOPARTICLES; HIGHER EFFICIENCY; INTRACELLULAR ACCUMULATION; METHYL METHACRYLATES; PROSTATE CANCERS; SOLID TUMORS;

PHOTODYNAMIC THERAPY;

BRCA1 PROTEIN; CD146 ANTIGEN; FLUORESCENT NANOPARTICLE; METHYLENE BLUE; NANOPARTICLE; PHTHALOCYANINE ALUMINUM; PLASMINOGEN ACTIVATOR; POLY(METHYL METHACRYLATE); QUATERNARY AMMONIUM DERIVATIVE; REACTIVE OXYGEN METABOLITE; SINGLET OXYGEN; THROMBOSPONDIN 1; UNCLASSIFIED DRUG; INDOLE DERIVATIVE; PHOTOSENSITIZING AGENT; PHTHALOCYANINE;

ACTIN FILAMENT; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL DEATH; CELL KILLING; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOFLUOROMETRY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; FLUORESCENCE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; LEACHING; MALE; MITOSIS; MONOCYTE; MOUSE; NEAR INFRARED PHOTOACTIVATION; NONHUMAN; OXYGEN POISONING; PHOTOACTIVATION; PHOTODYNAMIC THERAPY; PHOTON CORRELATION SPECTROSCOPY; PHOTOSTIMULATION; QUANTITATIVE ANALYSIS; TIME LAPSE IMAGING; TUMOR CELL; TUMOR VOLUME; TUNEL ASSAY; ZETA POTENTIAL; ANIMAL; PHOTOCHEMOTHERAPY; PROCEDURES; PROSTATIC NEOPLASMS; SCID MOUSE; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; HUMANS; INDOLES; MALE; MICE; MICE, SCID; NANOPARTICLES; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; PROSTATIC NEOPLASMS;

EID: 84973497882     PISSN: 15499634     EISSN: 15499642     Source Type: Journal    
DOI: 10.1016/j.nano.2016.04.014     Document Type: Article

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