Multifunctional ZnPc-loaded mesoporous silica nanoparticles for enhancement of photodynamic therapy efficacy by endolysosomal escape

Biomaterials

Volumn 33, Issue 31, 2012, Pages 7903-7914

  Tu, Jing ^a   Wang, Tianxiao ^a   Shi, Wei ^a   Wu, Guisen ^a   Tian, Xinhua ^b   Wang, Yuhua ^b   Ge, Dongtao ^a   Ren, Lei ^a,c  

^a XIAMEN UNIVERSITY   (China)

^b ZHONGSHAN HOSPITAL OF XIAMEN UNIVERSITY   (China)

^c XIAMEN UNIVERSITY   (China)

Author keywords

Endolysosomal escape; Mesoporous silica nanoparticles; Photodynamic therapy; Polyethylene glycol; Polyethylenimine

Indexed keywords

AFTER-TREATMENT; CANCER THERAPY; CELLULAR UPTAKE; CYTOSOLS; ENDOLYSOSOMAL ESCAPE; FUNCTIONALIZED; IN-VITRO; INTRAVENOUS INJECTIONS; LIGHT EXPOSURE; MESOPOROUS SILICA NANOPARTICLES; MITOCHONDRIAL MEMBRANE POTENTIAL; NANOCARRIERS; PHOTO-TOXICITY; POLYETHYLENIMINES; PROTON SPONGE; SIGNIFICANT IMPACTS; SINGLET OXYGEN; TUMOR TARGETING;

BIOCOMPATIBILITY; ENZYME INHIBITION; PHOTOSENSITIZERS; POLYETHYLENE GLYCOLS; TUMORS; ZINC COMPOUNDS;

PHOTODYNAMIC THERAPY;

MACROGOL; MESOPOROUS SILICA NANOPARTICLE; NANOCARRIER; NANOPARTICLE; PHTHALOCYANINE ZINC; POLYETHYLENEIMINE; SILICON DIOXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; CANCER THERAPY; CLINICAL EFFECTIVENESS; CYTOSOL; ENCAPSULATION; FEMALE; IN VITRO STUDY; LIGHT EXPOSURE; LYSOSOME; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; PRIORITY JOURNAL;

ANIMALS; CELL DEATH; CELL LINE, TUMOR; ENDOSOMES; FLOW CYTOMETRY; INDOLES; INTRACELLULAR SPACE; LYSOSOMES; MICE; NANOPARTICLES; ORGANOMETALLIC COMPOUNDS; PHOTOCHEMOTHERAPY; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; POROSITY; SILICON DIOXIDE; TISSUE DISTRIBUTION; TREATMENT OUTCOME;

MUS;

EID: 84865198470     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.07.025     Document Type: Article

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