Enhanced photodynamic cancer treatment by supramolecular nanocarriers charged with dendrimer phthalocyanine

Journal of Controlled Release

Volumn 133, Issue 3, 2009, Pages 245-251

  Nishiyama, Nobuhiro ^a   Nakagishi, Yoshinori ^c   Morimoto, Yuji ^c   Lai, Ping Shan ^d   Miyazaki, Kozo ^a,c   Urano, Kyoko ^a,c   Horie, Souta ^a   Kumagai, Michiaki ^a   Fukushima, Shigeto ^a   Cheng, Yu ^b   Jang, Woo Dong ^e   Kikuchi, Makoto ^c   Kataoka, Kazunori ^a,b  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^e Yonsei University   (South Korea)

Author keywords

Dendrimer; Photodynamic therapy; Phthalocyanine; Polymeric micelle

Indexed keywords

CELL DEATH; CELL MEMBRANES; CYTOLOGY; DENDRIMERS; ESTERS; MICELLES; OPTICAL MATERIALS; PHOTOSENSITIZERS; PLASMONS;

A549 CELLS; DENDRIMER; DENDRIMER PHTHALOCYANINE; HALOGEN LAMPS; HIGH POWERS; HUMAN LUNGS; IN-VIVO; LOW POWERS; PHOTODYNAMIC THERAPY (PDT); PHOTOFRIN; PHTHALOCYANINE; POLYMERIC MICELLE; SOLID TUMORS;

PHOTODYNAMIC THERAPY;

DENDRIMER; NANOCARRIER; PHOTOFRIN; PHTHALOCYANINE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER THERAPY; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIODE LASER; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IRRADIATION; LUNG ADENOCARCINOMA; MITOCHONDRION; MOUSE; NONHUMAN; PHOTOCHEMISTRY; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; PRIORITY JOURNAL; SKIN TOXICITY; SUPRAMOLECULAR CHEMISTRY;

ANIMALS; CELL LINE, TUMOR; CELL SURVIVAL; DENDRIMERS; DIHEMATOPORPHYRIN ETHER; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; INDOLES; LASERS; LIVER; MICE; MICE, INBRED BALB C; MICELLES; NANOPARTICLES; NEOPLASMS; PHOTOCHEMOTHERAPY; POLYETHYLENE GLYCOLS; POLYLYSINE; RADIATION-SENSITIZING AGENTS; REACTIVE OXYGEN SPECIES; SKIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 58549111045     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2008.10.010     Document Type: Article

References (28)

1. Dolmans D.E.J.G.J., Fukumura D., and Jain R.K. Photodynamic therapy for cancer. Nat. Rev. Cancer 3 5 (2003) 380-387
2. Dougherty T.J., Gomer C.J., Henderson B.W., Jori G., Kessel D., Korbelik M., Moan J., and Peng Q. Photodynamic therapy. J. Natl. Cancer Inst. 90 12 (1998) 889-905
3. Macdonald I.J., and Dougherty T.J. Basic principles of photodynamic therapy. J. Porphyr. Phthalocyanines 5 2 (2001) 105-129
4. Derycke A.S.L., and de Whitte P.A.M. Liposomes for photodynamic therapy. Adv. Drug Deliv. Rev. 56 1 (2004) 17-30
5. 6 and adriamycin conjugates in combination treatments. Clin. Cancer Res. 6 3 (2000) 1008-1015
6. Hamblin M.R., Miller J.L., Rizvi I., Ortel B., Maytin E.V., and Hasan T. Pegylation of a chlorine6 polymer conjugate increases tumor targeting of photosensitizer. Cancer Res. 61 19 (2001) 7155-7162
7. Kojima C., Toi Y., Harada A., and Kono K. Preparation of poly(ethylene glycol)-attached dendrimers encapsulating photosensitizers for application to photodynamic therapy. Bioconjug. Chem. 18 3 (2007) 663-670
8. van Nostrum C.F. Polymeric micelles to deliver photosensitizers for photodynamic therapy. Adv. Drug Deliv. Rev. 56 1 (2004) 9-16
9. Le Garrec D., Taillefer J., Van Lier J.E., Lenaerts V., and Leroux J.-C. Optimizing pH-responsive polymeric micelles for drug delivery in a cancer photodynamic therapy model. J. Drug Target. 10 5 (2002) 429-437
10. Stapert H.R., Nishiyama N., Jiang D.L., Aida T., and Kataoka K. Polyion complex micelles encapsulating light-harvesting ionic dendrimer zinc porphyrins. Langmuir 16 21 (2000) 8182-8188
11. Matsumura Y., and Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent SMANCS. Cancer Res. 46 12 (1986) 6387-6392
12. Cauchon N., Tian H., Langlois R., La Madeleine C., Martin S., Ali H., Hunting D., and van Lier J.E. Structure-photodynamic activity relationships of substituted zinc trisulfophthalocyanines. Bioconjug. Chem. 16 1 (2005) 80-89
13. Li Y., Jang W.-D., Nishiyama N., Kishimura A., Kawauchi S., Morimoto Y., Miake S., Yamashita T., Kikuchi M., Aida T., and Kataoka K. Dendrimer generation effects on photodynamic efficacy of dendrimer porphyrins and dendrimer-loaded supramolecular nanocarriers. Chem. Mater. 19 23 (2007) 5557-5562
14. Nishiyama N., Stapert H.R., Zhang G.D., Takasu D., Jiang D.L., Nagano T., Aida T., and Kataoka K. Light-harvesting ionic dendrimer porphyrins as new photosensitizers for photodynamic therapy. Bioconjug. Chem. 14 1 (2003) 58-66
15. Jang W.-D., Nakagishi Y., Nishiyama N., Kawauchi S., Morimoto Y., Kikuchi M., and Kataoka K. Polyion complex micelle for photodynamic therapy: incorporation of dendritic photosensitizer excitable at long wavelength relevant to improved tissue-penetrating property. J. Control. Release 113 1 (2006) 73-79
16. Jang W.-D., Nishiyama N., Zhang G.D., Harada A., Jiang D.-L., Kawauci S., Morimoto Y., Kikuchi M., Koyama H., Aida T., and Kataoka K. Supramolecular nanocarrier of anionic dendrimer porphyrins with cationic block copolymers modified with polyethylene glycol to enhance intracellular photodynamic efficacy. Angew. Chem., Int. Ed. 44 3 (2005) 419-423
17. Nishiyama N., Okazaki S., Cabral H., Miyamoto M., Kato Y., Sugiyama Y., Nishio K., Matsumura Y., and Kataoka K. Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in mice. Cancer Res. 63 24 (2003) 8977-8983
18. Kataoka K., Harada A., and Nagasaki Y. Block copolymer micelles for drug delivery: design, characterization and biological significance. Adv. Drug Deliv. Rev. 47 1 (2001) 113-131
19. Nishiyama N., and Kataoka K. Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery. Pharmacol. Ther. 112 3 (2006) 630-648
20. Ideta R., Tasaka F., Jang W.-D., Nishiyama N., Zhang G.-D., Harada A., Yanagi Y., Tamaki Y., Aida T., and Kataoka K. Nanotechnology-based photodynamic therapy for neovascular disease using a supramolecular nanocarrier loaded with a dendritic photosensitizer. Nano Lett. 5 12 (2005) 2426-2431
21. Sheng Z., Ye X., Zheng Z., Yu S., Ng D.K.P., Ngai T., and Wu C. Transient absorption and fluorescence studies of disstacking phthalocyanine by poly(ethylene oxide). Macromolecules 35 9 (2002) 3681-3685
22. Harada A., and Kataoka K. Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely-charged block copolymers with poly(ethylene glycol) segments. Macromolecules 28 15 (1995) 5294-5299
23. Majno G., and Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am. J. Phathol. 146 1 (1995) 3-15
24. Berg K., Selbo P.K., Prasmickaite L., Tjelle T.E., Sandvig K., Moan J., Gaudernack G., Fodstad O., Kjolsrud S., Anholt H., Rodal G.H., Rodal S.K., and Hogset A. Photochemical internalization: a novel technology for delivery of macromolecules into cytosol. Cancer Res. 59 6 (1999) 1180-1183
25. Hogset A., Prasmickaite L., Selbo P.K., Hellum M., Engesaeter B.O., Bonsted A., and Berg K. Photochemical internalization in drug and gene delivery. Adv. Drug Deliv. Rev. 56 1 (2004) 95-115
26. Nishiyama N., Arnida, Jang W.-D., Date K., Miyata K., and Kataoka K. Photochemical enhancement of transgene expression by polymeric micelles incorporating plasmid DNA and dendrimer-based photosensitizer. J. Drug Target. 14 6 (2006) 413-424
27. Nishiyama N., Iriyama A., Jang W.D., Miyata K., Itaka K., Inoue Y., Takahashi H., Yanagi Y., Tamaki Y., Koyama H., and Kataoka K. Light-induced gene transfer from packaged DNA enveloped in a dendrimeric photosensitizer. Nature Mater. 4 12 (2005) 934-941
28. Downes C.S., Ord M.J., Mullinger A.M., Collinsm A.R., and Johnson R.T. Novobiocin inhibition of DNA excision repair may occur through effects on mitochondrial structure and ATP metabolism, not on repair topoisomerases. Carcinogenesis 6 9 (1985) 1343-1352