The protective effect of regulation of paraoxonase 1 gene on liver oxidative stress injury induced by dichlorvos poisoning in mice

Chinese Critical Care Medicine

Volumn 27, Issue 4, 2015, Pages 285-290

  Ruijuan, Guo ^a   Longwang, Chen ^a   Jie, Lian ^a   Bin, Wu ^a   Guangliang, Hong ^a   Yun, Ge ^a   Yao, Liu ^a   Qiaomeng, Qiu ^a   Zhongqiu, Lu ^a  

^a THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Dichlorvos; Liver injury; Oxidative stress; Paraoxonase; Poisoning

Indexed keywords

ARYLDIALKYLPHOSPHATASE 1; CATALASE; DICHLORVOS; GLUTATHIONE; GREEN FLUORESCENT PROTEIN; MALONALDEHYDE; MESSENGER RNA; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NF E2; ARYLDIALKYLPHOSPHATASE; PON1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR NRF2; LENTIVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; BLOOD SAMPLING; COLORIMETRY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE CONTROL; GENE EXPRESSION; GENETIC TRANSFECTION; INTOXICATION; LENTIVIRINAE; LIVER INJURY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TAIL VEIN; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; INJURIES; LIVER; LIVER PROTECTION; PON1 GENE; PROTEIN BLOOD LEVEL; UPREGULATION; VIRUS RECOMBINANT;

ANIMALS; ARYLDIALKYLPHOSPHATASE; DICHLORVOS; LIVER; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED BALB C; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RNA, MESSENGER; SUPEROXIDE DISMUTASE;

EID: 84973427408     PISSN: 10030603     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.2095-4352.2015.04.012     Document Type: Article

References (16)

1. Eddleston M, Phillips MR. Self poisoning with pesticides[J]. BMJ, 2004, 328(7430): 42-44.
2. Ki{dotless}r MZ, Öztürk G, Gürler M, et al. Pesticide poisoning cases in Ankara and nearby cities in Turkey: an 11-year retrospective analysis[J]. J Forensic Leg Med, 2013, 20(4): 274-277.
3. Lu L, Wang X, Lang L, et al. Protective effect of reduced glutathione on the liver injury induced by acute omethoate poisoning[J]. Environ Toxicol Pharmacol, 2010, 30(3): 279-283.
4. Mohineesh, Raj J, Rajvanshi AC, et al. Effect of acute exposure of triazophos on oxidative stress and histopathological alterations in liver, kidney and brain of Wistar rats[J]. Indian J Exp Biol, 2014, 52(8): 814-819.
5. Mackness MI, Harty D, Bhatnagar D, et al. Serum paraoxonase activity in familial hypercholesterolaemia and insulin-dependent diabetes mellitus[J]. Atherosclerosis, 1991, 86(2-3): 193-199.
6. Alonso-Navarro H, Jimenez-Jimenez FJ, Garcia-Martin E, et al. Genomic and pharmacogenomic biomarkers of Parkinson's disease[J]. Curr Drug Metab, 2014, 15(2): 129-181.
7. Menini T, Gugliucci A. Paraoxonase 1 in neurological disorders [J]. Redox Rep, 2014, 19(2): 49-58.
8. Surajudeen YA, Sheu RK, Ayokulehin KM, et al. Oxidative stress indices in Nigerian pesticide applicators and farmers occupationally exposed to organophosphate pesticides[J]. Int J Appl Basic Med Res, 2014, 4(Suppl 1): S37-40.
9. Kulkarni SR, Donepudi AC, Xu J, et al. Fasting induces nuclear factor E2-related factor 2 and ATP-binding Cassette transporters via protein kinase A and Sirtuin-1 in mouse and human[J]. Antioxid Redox Signal, 2014, 20(1): 15-30.
10. Aleksunes LM, Manautou JE. Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease[J]. Toxicol Pathol, 2007, 35(4): 459-473.
11. Okawa H, Motohashi H, Kobayashi A, et al. Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity[J]. Biochem Biophys Res Commun, 2006, 339(1): 79-88.
12. Klaassen CD, Reisman SA. Nrf2 the rescue: effects of the antioxidative/electrophilic response on the liver[J]. Toxicol Appl Pharmacol, 2010, 244(1): 57-65.
13. Furlong CE, Cole TB, Jarvik GP, et al. Pharmacogenomic considerations of the paraoxonase polymorphisms[J]. Pharmacogenomics, 2002, 3(3): 341-348.
14. Łukaszewicz-Hussain A. Paraoxonase activity and lipid peroxides concentration in serum of rats subchronically intoxicated withchlorpyrifos-organophosphate insecticide[J]. Med Pr, 2012, 63(5): 559-564.
15. Zhang JW, Lv GC, Zhao Y. The significance of the measurement of serum xanthine oxidase and oxidation markers in patients with acute organophosphorus pesticide poisoning[J]. J Int Med Res, 2010, 38(2): 458-465.
16. Zhang C, Peng W, Wang M, et al. Studies on protective effects of human paraoxonases 1 and 3 on atherosclerosis in apolipoprotein E knockout mice[J]. Gene Ther, 2010, 17(5): 626-633.