The significance of the measurement of serum xanthine oxidase and oxidation markers in patients with Acute Organophosphorus Pesticide Poisoning

Journal of International Medical Research

Volumn 38, Issue 2, 2010, Pages 458-465

  Zhang, J W ^a   Lv, G C ^a   Zhao, Y ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Acute organophosphorus pesticide poisoning; Butyrylcholinesterase; Malondialdehyde; Organophosphorus pesticides; Paraoxonase 1; Superoxide dismutase; Xanthine oxidase

Indexed keywords

ARYLDIALKYLPHOSPHATASE 1; BIOLOGICAL MARKER; CHOLINESTERASE; MALONALDEHYDE; ORGANOPHOSPHATE PESTICIDE; SUPEROXIDE DISMUTASE; XANTHINE OXIDASE;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATIONAL STUDY; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; HUMAN; INTOXICATION; MALE; OXIDATIVE STRESS; PROTEIN FUNCTION;

EID: 77953695527     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323001003800209     Document Type: Article

References (32)

1. Jokanović M, Prostran M: Pyridinium oximes as cholinesterase reactivators. Structure-activity relationship and efficacy in the treatment of poisoning with organophosphorus compounds. Curr Med Chem 2009; 16: 2177-2188.
2. Sanz P, Rodriguez-Vicente MC, Daiz D: Red blood cell and total blood acetylcholinesterase and plasma pseudocholinesterase in humans: observed variances. J Toxlcol Clin Toxicol 1991; 29: 81-90.
3. Cataño HC, Carranza E, Huamaní C, et al: Plasma cholinesterase levels and health symptoms in Peruvian farm workers exposed to organophosphate pesticides. Arch Environ Contam Toxicol 2008; 55: 153-159.
4. Costa LG: Current issues in organophosphate toxicology. Clin Chim Acta 2006; 366: 1-13.
5. Baneriee BD, Seth V, Bhattacharya A, et al: Biochemical effects of some pesticides on lipid peroxidation and free radicals scavengers. Toxicol Lett 1999; 107: 33-47.
6. Zhou JF, Xu GB, Fang WJ: Relationship between acute organophosphorus pesticide poisoning and damages induced by free radicals. Biomed Environ Sci 2002; 15: 177-186.
7. Akhgari M, Abdollahi M, Kebryaeezadeh A, et al: Biochemical evidence for free radical-induced lipid peroxidation as a mechanism for subchronic toxicity of malathion in blood and liver of rats. Hum Exp Toxicol 2003; 22: 205 -211.
8. Ranjbar A, Solhi H, Mashayekhi FJ, et al: Oxidative stress in acute human poisoning with organophosphorus insecticides: a case control study. Environ Toxicol Pharmacol 2005; 20: 88-91.
9. Aranda R, Doménech E, Rus AD, et al Age-related increase in xanthine oxidase activity in human plasma and rat tissues. Free Radic Res 2007; 41: 1195-1200.
10. Chambers DE, Parks DA, Patterson G, et al: Xanthine oxidase as a source of free radical damage in myocardiol ischemia. J Mol Cell Cardiol 1985; 17: 145-152.
11. Landmesser U, Spiekermann S, Dikalov S, et al: Vascular oxidative stress and endothelial dysfunction in patients with chronic heart failure: role of xanthine oxidase and extracellular superoxide dismutase. Circulation 2002; 106: 3073-3078.
12. Fried R: Colorimetric determination of xanthine dehydrogenase by tetrazolium reduction. Anal Biochem 1966; 16: 427-432.
13. Xu GY, Lv GC, Chen Y, et al: Monitoring the level of serum paraoxonase 1 activity in liver transplantation patients. Hepatobiliary Pancreat Dislnt 2005; 4: 178-181.
14. Beauchamp C, Fridovich I: Superoxide dismutase: improved assays and an assay applicable to acrylamide gels. Anal Biochem 1971; 44: 276-287.
15. Uchiyama M, Mihara M: Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 1978; 86: 271-278.
16. Ellman GL, Courtney KD, Andres V, et al: A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 1961; 7:88-95.
17. Berry CE, Hare JM: Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications. J Physiol 2004; 555: 589-606.
18. Wajner M., Harkness RA.: Distribution of xanthine dehydrogenase and oxidase activities in human and rabbit tissues. Biochim Biophys Acta 1989; 991: 79-84.
19. Nishino T, Okamoto K, Kawaguchi Y, et al Mechanism of the conversion of xanthine dehydrogenase to xanthine oxidase: identification of the two cysteine disulfide bonds and crystal structure of a nonconvertible rat liver xanthine dehydrogenase mutant. J Biol Chem 2005; 280: 24888-24894.
20. Poggetti RS, Moore FA, Moore EE, et al: Simultaneous liver and lung injury following gut ischemia is mediated by xanthine oxidase. J Trauma 1992; 32: 723-727.
21. Granger DN: Role of xanthine oxidase and granulocytes in ischemia-reperfusion injury. Am J Physiol 1988; 255: H1269-H1275.
22. Webster NR, Toothill C: Effects of blood storage on red cell antioxidative systems. Acta Haematol 1986; 75: 30-33.
23. Costa LG, Cole TB, Vitalone A, et al Measurement of paraoxonase (PON1) status as a potential biomarker of susceptibility to organophosphate toxicity. Clin Chim Acta 2005; 352: 37-47.
24. Camps J, Marsillach J, Joven J: The paraoxonases: role in human diseases and methodological difficulties in measurement. Crif Rev Clin Lab Sci 2009; 46: 83-106.
25. Rozenberg O, Shiner M, Aviram M, et al: Paraoxonase 1 (PON1) attenuates diabetes development in mice through its antioxidative properties. Free Radic Biol Med 2008; 44: 1951 -1959.
26. Sözmen EY, Mackness B, Sözmen B, et al: Effect of organophosphate intoxication on human serum paraoxonase. Hum Exp Toxlcol 2002; 21: 247-252.
27. Valko M, Leibfritz D, Moncol J, et al Free radicals and antioxidants in normal physiological functions and human disease. Int I Biochem Cell Biol 2007; 39: 44-84.
28. Ji LL: Oxidative stress during exercise: implication of antioxidant nutrients. Free Radic Biol Med 1995; 18: 1079-1086.
29. López O, Hernández AF, Rodrigo L, et al: Changes in antioxidant enzymes in humans with long-term exposure to pesticides. Toxicol Lett 2007; 171: 146-153.
30. Eddleston M, Mohamed F, Davies JO, et al Respiratory failure in acute organophosphorus pesticide self-poisoning. QJM 2006; 99: 513 -522.
31. Fink MP: Cytopathic hypoxia. Mitochondrial dysfunction as mechanism contributing to organ dysfunction in sepsis. Crif Care Clin 2001; 17:219-237.
32. Rochu D, Chabrière E, Masson P, et al: Human paraoxonase: A promising approach for pre-treatment and therapy of organophosphorus poisoning. Toxicology 2007; 233: 47-59.