메뉴 건너뛰기




Volumn 113, Issue 23, 2016, Pages E3260-E3269

Coxiella burnetii effector CvpB modulates phosphoinositide metabolism for optimal vacuole development

Author keywords

Coxiella burnetii; Host pathogen interactions; Phosphoinositides

Indexed keywords

BACTERIAL PROTEIN; CELL PROTEIN; COXIELLA VACUOLAR PROTEIN B; LACTADHERIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PHOSPHATIDYLSERINE; UNCLASSIFIED DRUG; BACTERIAL SECRETION SYSTEM; POLYPHOSPHOINOSITIDE;

EID: 84973344436     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1522811113     Document Type: Article
Times cited : (85)

References (52)
  • 1
    • 84880506847 scopus 로고    scopus 로고
    • Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii
    • van Schaik EJ, Chen C, Mertens K, Weber MM, Samuel JE (2013) Molecular pathogenesis of the obligate intracellular bacterium Coxiella burnetii. Nat Rev Microbiol 11(8):561-573.
    • (2013) Nat Rev Microbiol , vol.11 , Issue.8 , pp. 561-573
    • Van Schaik, E.J.1    Chen, C.2    Mertens, K.3    Weber, M.M.4    Samuel, J.E.5
  • 3
    • 84872577094 scopus 로고    scopus 로고
    • Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole
    • Newton HJ, McDonough JA, Roy CR (2013) Effector protein translocation by the Coxiella burnetii Dot/Icm type IV secretion system requires endocytic maturation of the pathogen-occupied vacuole. PLoS One 8(1):e54566-e54569.
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e54566-e54569
    • Newton, H.J.1    McDonough, J.A.2    Roy, C.R.3
  • 4
    • 84927710799 scopus 로고    scopus 로고
    • Coxiella burnetii: Turning hostility into a home
    • Moffatt JH, Newton P, Newton HJ (2015) Coxiella burnetii: Turning hostility into a home. Cell Microbiol 17(5):621-631.
    • (2015) Cell Microbiol , vol.17 , Issue.5 , pp. 621-631
    • Moffatt, J.H.1    Newton, P.2    Newton, H.J.3
  • 5
    • 84877809004 scopus 로고    scopus 로고
    • Endocytic SNAREs are involved in optimal Coxiella burnetii vacuole development
    • Campoy EM, Mansilla ME, Colombo MI (2013) Endocytic SNAREs are involved in optimal Coxiella burnetii vacuole development. Cell Microbiol 15(6):922-941.
    • (2013) Cell Microbiol , vol.15 , Issue.6 , pp. 922-941
    • Campoy, E.M.1    Mansilla, M.E.2    Colombo, M.I.3
  • 7
    • 84945905164 scopus 로고    scopus 로고
    • Biogenesis of the lysosome-derived vacuole containing Coxiella burnetii
    • Kohler LJ, Roy CR (2015) Biogenesis of the lysosome-derived vacuole containing Coxiella burnetii. Microbes Infect 17(11-12):766-771, 10.1016/j.micinf.2015.08.006.
    • (2015) Microbes Infect , vol.17 , Issue.11-12 , pp. 766-771
    • Kohler, L.J.1    Roy, C.R.2
  • 8
    • 84905395102 scopus 로고    scopus 로고
    • A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesis
    • Newton HJ, et al. (2014) A screen of Coxiella burnetii mutants reveals important roles for Dot/Icm effectors and host autophagy in vacuole biogenesis. PLoS Pathog 10(7): e1004286-e16.
    • (2014) PLoS Pathog , vol.10 , Issue.7 , pp. e1004286-e1005316
    • Newton, H.J.1
  • 9
    • 84921417506 scopus 로고    scopus 로고
    • Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication
    • Larson CL, et al. (2015) Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication. Infect Immun 83(2): 661-670.
    • (2015) Infect Immun , vol.83 , Issue.2 , pp. 661-670
    • Larson, C.L.1
  • 10
    • 2942718545 scopus 로고    scopus 로고
    • PI-loting membrane traffic
    • De Matteis MA, Godi A (2004) PI-loting membrane traffic. Nat Cell Biol 6(6):487-492.
    • (2004) Nat Cell Biol , vol.6 , Issue.6 , pp. 487-492
    • De Matteis, M.A.1    Godi, A.2
  • 11
    • 62449280568 scopus 로고    scopus 로고
    • Pathogen trafficking pathways and host phosphoinositide metabolism
    • Weber SS, Ragaz C, Hilbi H (2009) Pathogen trafficking pathways and host phosphoinositide metabolism. Mol Microbiol 71(6):1341-1352.
    • (2009) Mol Microbiol , vol.71 , Issue.6 , pp. 1341-1352
    • Weber, S.S.1    Ragaz, C.2    Hilbi, H.3
  • 13
    • 7944228843 scopus 로고    scopus 로고
    • Subversion of phosphoinositide metabolism by intracellular bacterial pathogens
    • Pizarro-Cerdá J, Cossart P (2004) Subversion of phosphoinositide metabolism by intracellular bacterial pathogens. Nat Cell Biol 6(11):1026-1033.
    • (2004) Nat Cell Biol , vol.6 , Issue.11 , pp. 1026-1033
    • Pizarro-Cerdá, J.1    Cossart, P.2
  • 14
    • 84897434413 scopus 로고    scopus 로고
    • Identification of OmpA, a Coxiella burnetii protein involved in host cell invasion, by multi-phenotypic highcontent screening
    • Martinez E, Cantet F, Fava L, Norville I, Bonazzi M (2014) Identification of OmpA, a Coxiella burnetii protein involved in host cell invasion, by multi-phenotypic highcontent screening. PLoS Pathog 10(3):e1004013-e1004022.
    • (2014) PLoS Pathog , vol.10 , Issue.3 , pp. e1004013-e1004022
    • Martinez, E.1    Cantet, F.2    Fava, L.3    Norville, I.4    Bonazzi, M.5
  • 15
    • 84941254094 scopus 로고    scopus 로고
    • Generation and multi-phenotypic high-content screening of Coxiella burnetii transposon mutants
    • Martinez E, Cantet F, Bonazzi M (2015) Generation and multi-phenotypic high-content screening of Coxiella burnetii transposon mutants. J Vis Exp (99):e52851-e52851.
    • (2015) J Vis Exp , Issue.99 , pp. e52851-e52851
    • Martinez, E.1    Cantet, F.2    Bonazzi, M.3
  • 16
    • 0038649869 scopus 로고    scopus 로고
    • Functional similarities between the icm/dot pathogenesis systems of Coxiella burnetii and Legionella pneumophila
    • Zusman T, Yerushalmi G, Segal G (2003) Functional similarities between the icm/dot pathogenesis systems of Coxiella burnetii and Legionella pneumophila. Infect Immun 71(7):3714-3723.
    • (2003) Infect Immun , vol.71 , Issue.7 , pp. 3714-3723
    • Zusman, T.1    Yerushalmi, G.2    Segal, G.3
  • 17
    • 13444262298 scopus 로고    scopus 로고
    • The Legionella IcmSIcmW protein complex is important for Dot/Icm-mediated protein translocation
    • Ninio S, Zuckman-Cholon DM, Cambronne ED, Roy CR (2005) The Legionella IcmSIcmW protein complex is important for Dot/Icm-mediated protein translocation. Mol Microbiol 55(3):912-926.
    • (2005) Mol Microbiol , vol.55 , Issue.3 , pp. 912-926
    • Ninio, S.1    Zuckman-Cholon, D.M.2    Cambronne, E.D.3    Roy, C.R.4
  • 18
    • 84899764479 scopus 로고    scopus 로고
    • Essential role for the response regulator PmrA in Coxiella burnetii type 4B secretion and colonization of mammalian host cells
    • Beare PA, et al. (2014) Essential role for the response regulator PmrA in Coxiella burnetii type 4B secretion and colonization of mammalian host cells. J Bacteriol 196(11):1925-1940.
    • (2014) J Bacteriol , vol.196 , Issue.11 , pp. 1925-1940
    • Beare, P.A.1
  • 19
    • 84874280135 scopus 로고    scopus 로고
    • Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal
    • Lifshitz Z, et al. (2013) Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal. Proc Natl Acad Sci USA 110(8):E707-E715.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.8 , pp. E707-E715
    • Lifshitz, Z.1
  • 20
    • 84901697934 scopus 로고    scopus 로고
    • Galleria mellonella as an alternative model of Coxiella burnetii infection
    • Norville IH, et al. (2014) Galleria mellonella as an alternative model of Coxiella burnetii infection. Microbiology 160(Pt 6):1175-1181.
    • (2014) Microbiology , vol.160 , Issue.6 , pp. 1175-1181
    • Norville, I.H.1
  • 22
    • 80053157437 scopus 로고    scopus 로고
    • Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes
    • Uchida Y, et al. (2011) Intracellular phosphatidylserine is essential for retrograde membrane traffic through endosomes. Proc Natl Acad Sci USA 108(38):15846-15851.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.38 , pp. 15846-15851
    • Uchida, Y.1
  • 23
    • 0035854730 scopus 로고    scopus 로고
    • Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve
    • Ikonomov OC, Sbrissa D, Shisheva A (2001) Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve. J Biol Chem 276(28):26141-26147.
    • (2001) J Biol Chem , vol.276 , Issue.28 , pp. 26141-26147
    • Ikonomov, O.C.1    Sbrissa, D.2    Shisheva, A.3
  • 24
    • 33746586545 scopus 로고    scopus 로고
    • Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion
    • Ikonomov OC, Sbrissa D, Shisheva A (2006) Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion. Am J Physiol Cell Physiol 291(2): C393-C404.
    • (2006) Am J Physiol Cell Physiol , vol.291 , Issue.2 , pp. C393-C404
    • Ikonomov, O.C.1    Sbrissa, D.2    Shisheva, A.3
  • 25
    • 38949207192 scopus 로고    scopus 로고
    • A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding
    • Jefferies HBJ, et al. (2008) A selective PIKfyve inhibitor blocks PtdIns(3,5)P(2) production and disrupts endomembrane transport and retroviral budding. EMBO Rep 9(2):164-170.
    • (2008) EMBO Rep , vol.9 , Issue.2 , pp. 164-170
    • Hbj, J.1
  • 26
    • 0037155216 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve.Endomenbrane localization
    • Sbrissa D, Ikonomov OC, Shisheva A (2002) Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve.Endomenbrane localization. J Biol Chem 277(8):6073-6079.
    • (2002) J Biol Chem , vol.277 , Issue.8 , pp. 6073-6079
    • Sbrissa, D.1    Ikonomov, O.C.2    Shisheva, A.3
  • 27
    • 33645230242 scopus 로고    scopus 로고
    • Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase
    • Cabezas A, Pattni K, Stenmak H (2006) Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1. Gene 371(1):34-41.
    • (2006) PIKfyve/Fab1. Gene , vol.371 , Issue.1 , pp. 34-41
    • Cabezas, A.1    Pattni, K.2    Stenmak, H.3
  • 28
    • 84889658843 scopus 로고    scopus 로고
    • Coxiella burnetii effector protein subverts clathrin-mediated vesicular trafficking for pathogen vacuole biogenesis
    • Larson CL, Beare PA, Howe D (2013) Coxiella burnetii effector protein subverts clathrin-mediated vesicular trafficking for pathogen vacuole biogenesis. Proc Natl Acad Sci USA 110(49):E4770-E4779, 10.1073/pnas.1309195110/-/DCSupplemental.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.49 , pp. E4770-E4779
    • Larson, C.L.1    Beare, P.A.2    Howe, D.3
  • 29
    • 0036784707 scopus 로고    scopus 로고
    • Coxiella burnetii localizes in a Rab7-labeled compartment with autophagic characteristics
    • Berón W, Gutierrez MG, Rabinovitch M, Colombo MI (2002) Coxiella burnetii localizes in a Rab7-labeled compartment with autophagic characteristics. Infect Immun 70(10): 5816-5821.
    • (2002) Infect Immun , vol.70 , Issue.10 , pp. 5816-5821
    • Berón, W.1    Gutierrez, M.G.2    Rabinovitch, M.3    Colombo, M.I.4
  • 30
    • 78650919752 scopus 로고    scopus 로고
    • The early secretory pathway contributes to the growth of the Coxiella-replicative niche
    • Campoy EM, Zoppino FCM, Colombo MI (2011) The early secretory pathway contributes to the growth of the Coxiella-replicative niche. Infect Immun 79(1):402-413.
    • (2011) Infect Immun , vol.79 , Issue.1 , pp. 402-413
    • Campoy, E.M.1    Fcm, Z.2    Colombo, M.I.3
  • 31
    • 84925665455 scopus 로고    scopus 로고
    • Phosphoinositides in phagocytosis and macropinocytosis
    • Levin R, Grinstein S, Schlam D (2015) Phosphoinositides in phagocytosis and macropinocytosis. Biochim Biophys Acta 1851(6):805-823.
    • (2015) Biochim Biophys Acta , vol.1851 , Issue.6 , pp. 805-823
    • Levin, R.1    Grinstein, S.2    Schlam, D.3
  • 33
    • 85020662729 scopus 로고    scopus 로고
    • Mirror image phosphoinositides regulate autophagy
    • Vicinanza M, Rubinsztein DC (2016) Mirror image phosphoinositides regulate autophagy. Mol Cell Oncol 3(2):e1019974, 10.1080/23723556.2015.1019974.
    • (2016) Mol Cell Oncol , vol.3 , Issue.2 , pp. e1019974
    • Vicinanza, M.1    Rubinsztein, D.C.2
  • 34
    • 82355174106 scopus 로고    scopus 로고
    • Anchors for effectors: Subversion of phosphoinositide lipids by legionella
    • Hilbi H, Weber S, Finsel I (2011) Anchors for effectors: Subversion of phosphoinositide lipids by legionella. Front Microbiol 2:91.
    • (2011) Front Microbiol , vol.2 , pp. 91
    • Hilbi, H.1    Weber, S.2    Finsel, I.3
  • 35
    • 0037627408 scopus 로고    scopus 로고
    • Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest
    • Fratti RA, Chua J, Vergne I, Deretic V (2003) Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. Proc Natl Acad Sci USA 100(9):5437-5442.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.9 , pp. 5437-5442
    • Fratti, R.A.1    Chua, J.2    Vergne, I.3    Deretic, V.4
  • 36
    • 15244340430 scopus 로고    scopus 로고
    • Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis
    • Vergne I, et al. (2005) Mechanism of phagolysosome biogenesis block by viable Mycobacterium tuberculosis. Proc Natl Acad Sci USA 102(11):4033-4038.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.11 , pp. 4033-4038
    • Vergne, I.1
  • 37
    • 84903363943 scopus 로고    scopus 로고
    • Live-cell imaging of phosphoinositide dynamics and membrane architecture during Legionella infection
    • Weber S, Wagner M, Hilbi H (2013) Live-cell imaging of phosphoinositide dynamics and membrane architecture during Legionella infection. mBio 5(1):e00839-13.
    • (2013) MBio , vol.5 , Issue.1 , pp. e00839-e00913
    • Weber, S.1    Wagner, M.2    Hilbi, H.3
  • 38
    • 84883143842 scopus 로고    scopus 로고
    • Identification and structural characterization of a Legionella phosphoinositide phosphatase
    • Toulabi L, Wu X, Cheng Y, Mao Y (2013) Identification and structural characterization of a Legionella phosphoinositide phosphatase. J Biol Chem 288(34):24518-24527.
    • (2013) J Biol Chem , vol.288 , Issue.34 , pp. 24518-24527
    • Toulabi, L.1    Wu, X.2    Cheng, Y.3    Mao, Y.4
  • 39
    • 50249176472 scopus 로고    scopus 로고
    • SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34
    • Mallo GV, et al. (2008) SopB promotes phosphatidylinositol 3-phosphate formation on Salmonella vacuoles by recruiting Rab5 and Vps34. J Cell Biol 182(4):741-752.
    • (2008) J Cell Biol , vol.182 , Issue.4 , pp. 741-752
    • Mallo, G.V.1
  • 40
    • 2942750147 scopus 로고    scopus 로고
    • Salmonella modulates vesicular traffic by altering phosphoinositide metabolism
    • Hernandez LD, Hueffer K, Wenk MR, Galán JE (2004) Salmonella modulates vesicular traffic by altering phosphoinositide metabolism. Science 304(5678):1805-1807.
    • (2004) Science , vol.304 , Issue.5678 , pp. 1805-1807
    • Hernandez, L.D.1    Hueffer, K.2    Wenk, M.R.3    Galán, J.E.4
  • 41
    • 0037066701 scopus 로고    scopus 로고
    • Role of 3-phosphoinositides in the maturation of Salmonella-containing vacuoles within host cells
    • Scott CC, Cuellar-Mata P, Matsuo T, Davidson HW, Grinstein S (2002) Role of 3-phosphoinositides in the maturation of Salmonella-containing vacuoles within host cells. J Biol Chem 277(15):12770-12776.
    • (2002) J Biol Chem , vol.277 , Issue.15 , pp. 12770-12776
    • Scott, C.C.1    Cuellar-Mata, P.2    Matsuo, T.3    Davidson, H.W.4    Grinstein, S.5
  • 42
    • 55749101951 scopus 로고    scopus 로고
    • The Legionella pneumophila phosphatidylinositol-4 phosphatebinding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replicationpermissive vacuole
    • Ragaz C, et al. (2008) The Legionella pneumophila phosphatidylinositol-4 phosphatebinding type IV substrate SidC recruits endoplasmic reticulum vesicles to a replicationpermissive vacuole. Cell Microbiol 10(12):2416-2433.
    • (2008) Cell Microbiol , vol.10 , Issue.12 , pp. 2416-2433
    • Ragaz, C.1
  • 43
    • 64149084796 scopus 로고    scopus 로고
    • Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila
    • Brombacher E, et al. (2009) Rab1 guanine nucleotide exchange factor SidM is a major phosphatidylinositol 4-phosphate-binding effector protein of Legionella pneumophila. J Biol Chem 284(8):4846-4856.
    • (2009) J Biol Chem , vol.284 , Issue.8 , pp. 4846-4856
    • Brombacher, E.1
  • 44
    • 67249143561 scopus 로고    scopus 로고
    • PIKfyve regulation of endosome-linked pathways
    • de Lartigue J, et al. (2009) PIKfyve regulation of endosome-linked pathways. Traffic 10(7):883-893.
    • (2009) Traffic , vol.10 , Issue.7 , pp. 883-893
    • De Lartigue, J.1
  • 45
    • 84908571786 scopus 로고    scopus 로고
    • PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages
    • Kim GHE, Dayam RM, Prashar A, Terebiznik M, Botelho RJ (2014) PIKfyve inhibition interferes with phagosome and endosome maturation in macrophages. Traffic 15(10):1143-1163.
    • (2014) Traffic , vol.15 , Issue.10 , pp. 1143-1163
    • Ghe, K.1    Dayam, R.M.2    Prashar, A.3    Terebiznik, M.4    Botelho, R.J.5
  • 46
    • 33750485772 scopus 로고    scopus 로고
    • The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport
    • Rutherford AC, et al. (2006) The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport. J Cell Sci 119(pt 19): 3944-3957.
    • (2006) J Cell Sci , vol.119 , Issue.19 , pp. 3944-3957
    • Rutherford, A.C.1
  • 47
    • 84875435923 scopus 로고    scopus 로고
    • Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death
    • Martin S, et al. (2013) Inhibition of PIKfyve by YM-201636 dysregulates autophagy and leads to apoptosis-independent neuronal cell death. PLoS One 8(3):e60152-e14.
    • (2013) PLoS One , vol.8 , Issue.3 , pp. e60152-e70214
    • Martin, S.1
  • 48
    • 84921615639 scopus 로고    scopus 로고
    • PI(5)P regulates autophagosome biogenesis
    • Vicinanza M, et al. (2015) PI(5)P regulates autophagosome biogenesis. Mol Cell 57(2): 219-234.
    • (2015) Mol Cell , vol.57 , Issue.2 , pp. 219-234
    • Vicinanza, M.1
  • 49
    • 70349919804 scopus 로고    scopus 로고
    • Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
    • Simonsen A, Tooze SA (2009) Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes. J Cell Biol 186(6):773-782.
    • (2009) J Cell Biol , vol.186 , Issue.6 , pp. 773-782
    • Simonsen, A.1    Tooze, S.A.2
  • 50
    • 77950505030 scopus 로고    scopus 로고
    • The role of PI3P phosphatases in the regulation of autophagy
    • Vergne I, Deretic V (2010) The role of PI3P phosphatases in the regulation of autophagy. FEBS Lett 584(7):1313-1318.
    • (2010) FEBS Lett , vol.584 , Issue.7 , pp. 1313-1318
    • Vergne, I.1    Deretic, V.2
  • 51
    • 77950506156 scopus 로고    scopus 로고
    • Regulation of autophagy by phosphatidylinositol 3-phosphate
    • Burman C, Ktistakis NT (2010) Regulation of autophagy by phosphatidylinositol 3-phosphate. FEBS Lett 584(7):1302-1312.
    • (2010) FEBS Lett , vol.584 , Issue.7 , pp. 1302-1312
    • Burman, C.1    Ktistakis, N.T.2
  • 52
    • 84900440490 scopus 로고    scopus 로고
    • Coxiella burnetii type IV secretion-dependent recruitment of macrophage autophagosomes
    • Winchell CG, Graham JG, Kurten RC, Voth DE (2014) Coxiella burnetii type IV secretion-dependent recruitment of macrophage autophagosomes. Infect Immun 82(6): 2229-2238.
    • (2014) Infect Immun , vol.82 , Issue.6 , pp. 2229-2238
    • Winchell, C.G.1    Graham, J.G.2    Kurten, R.C.3    Voth, D.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.