Coxiella burnetii localizes in a Rab7-labeled compartment with autophagic characteristics

Infection and Immunity

Volumn 70, Issue 10, 2002, Pages 5816-5821

  Berón, Walter ^a   Gutierrez, Maximiliano G ^a   Rabinovitch, Michel ^a   Colombo, Maria I ^a  

^a FACULTAD DE CIENCIAS MÉDICAS   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; CELL MARKER; DANSYLCADAVERINE; GREEN FLUORESCENT PROTEIN; GUANOSINE TRIPHOSPHATASE; ISOPROTEIN; MUTANT PROTEIN; PROTEIN; PROTEIN LC3; RAB PROTEIN; UNCLASSIFIED DRUG; WORTMANNIN;

ACIDITY; ANTIBACTERIAL ACTIVITY; ARTICLE; AUTOPHAGY; CELL LABELING; CELL VACUOLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; COXIELLA BURNETII; ENDOSOME; FEMALE; FLUORESCENCE MICROSCOPY; GENE CONSTRUCT; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; Q FEVER; WILD TYPE;

ANIMALS; AUTOPHAGY; CELL COMPARTMENTATION; COXIELLA BURNETII; HELA CELLS; HUMANS; MUTATION; Q FEVER; RAB GTP-BINDING PROTEINS; VACUOLES;

EID: 0036784707     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.10.5816-5821.2002     Document Type: Article

References (48)

1. Mechanisms of phagocytosis in macrophages
2. Phagocytosed live Listeria monocytogenes influences Rab5-regulated in vitro phagosome-endosome fusion
3. Increased expression of Rab5a correlates directly with accelerated maturation of Listeria monocytogenes phagosomes
4. Membrane trafficking along the phagocytic pathway
5. Monodansylcadaverine (MDC) is a specific in vivo marker for autophagic vacuoles
6. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
7. The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway
8. Rab7: A key to lysosome biogenesis
9. Deviant expression of Rab5 on phagosomes containing the intracellular pathogens Mycobacterium tuberculosis and Legionella pneumophila is associated with altered phagosomal fate
10. Mycobacterium tuberculosis and Legionella pneumophila phagosomes exhibit arrested maturation despite acquisition of Rab7
11. Modulation of phagosome biogenesis by Legionella pneumophila creates an organelle permissive for intracellular growth
12. Modular phosphoinositide-binding domains-their role in signalling and membrane trafficking
13. Mycobacterium tuberculosis phagosome
14. Molecular characterization of phagosomes
15. Biogenesis of phagolysosomes proceeds through a sequential series of interactions with the endocytic apparatus
16. Maturation of phagosomes is accompanied by changes in their fusion properties and size-selective acquisition of solute materials from endosomes
17. Studies on the mechanisms of autophagy: Formation of the autophagic vacuole
18. Studies on the mechanisms of autophagy: Maturation of the autophagic vacuole
19. Rab 7: An important regulator of late endocytic membrane traffic
20. Survival of Mycobacterium avium and Mycobacterium tuberculosis in acidified vacuoles of murine macrophages
21. Biosafety concerns and Coxiella burnetii
22. Biochemical stratagem for obligate parasitism of eukaryotic cells by Coxiella burnetii
23. Developmental biology of Coxiella burnettii
24. Differential interaction with endocytic and exocytic pathways distinguish parasitophorous vacuoles of Coxiella burnetii and Chlamydia trachomatis
25. Coxiella burnetii exhibits morphological change and delays phagolysosomal fusion after internalization by J774A.1 cells
26. LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing
27. Phosphoinositide lipids as signaling molecules: Common themes for signal transduction, cytoskeletal regulation, and membrane trafficking
28. Phagolysosomes of Coxiella burnetii-infected cell lines maintain an acidic pH during persistent infection
29. Phagocytosis and the actin cytoskeleton
30. The rab7 GTPase controls the maturation of Salmonella typhimurium-containing vacuoles in HeLa cells
31. Controlling the maturation of pathogen-containing vacuoles: A matter of life and death
32. A novel assay to study autophagy: Regulation of autophagosome vacuole size by amino acid deprivation
33. Induction of autophagy causes dramatic changes in the subcellular distribution of GFP-Rab24
34. The small GTP binding protein rab7 is essential for cellular vacuolation induced by Helicobacter pylori cytotoxin
35. Invasion and intracellular trafficking of Brucella abortus in nonphagocytic cells
36. Mutant Rab7 causes the accumulation of cathepsin D and cation-independent mannose 6-phosphate receptor in an early endocytic compartment
37. Lysosome proteins are redistributed during expression of a GTP-hydrolysis-defective rab5a
38. Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake
39. Impaired recruitment of the small GTPase rab7 correlates with the inhibition of phagosome maturation by Leishmania donovani promastigotes
40. 3-Methyladenine: Specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
41. Approaching the molecular mechanism of autophagy
42. Fusion between large phagocytic vesicles: Targeting of yeast and other particulates to phagolysosomes that shelter the bacterium Coxiella burnetii or the protozoan Leishmania amazonensis in Chinese hamster ovary cells
43. Entry and survival of Leishmania amazonensis amastigotes within phagolysosome-like vacuoles that shelter Coxiella burnetii in Chinese hamster ovary cells
44. Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7
45. Role of the small GTPase Rab7 in the late endocytic pathway
46. Cell biology of Legionella pneumophila
47. Infection of Vero cells with Coxiella burnetii phase II: Relative intracellular bacterial load and distribution estimated by confocal laser scanning microscopy and morphometry
48. Rab proteins as membrane organizers