메뉴 건너뛰기




Volumn 4, Issue 3, 2015, Pages

Dietary advanced glycation end products consumption as a direct modulator of insulin sensitivity in overweight humans: A study protocol for a double-blind, randomized, two period cross-over trial

Author keywords

Advanced glycation; Diet; Inflammation, carboxymethyllysine; Insulin secretion; Insulin sensitivity; Type 2 diabetes

Indexed keywords


EID: 84973177007     PISSN: None     EISSN: 19290748     Source Type: Journal    
DOI: 10.2196/resprot.4552     Document Type: Article
Times cited : (6)

References (35)
  • 1
    • 14544275997 scopus 로고    scopus 로고
    • Origins and evolution of the Western diet: Health implications for the 21st century
    • Feb; [FREE Full text] [Medline: 15699220]
    • Cordain L, Eaton SB, Sebastian A, Mann N, Lindeberg S, Watkins BA, et al. Origins and evolution of the Western diet: Health implications for the 21st century. Am J Clin Nutr 2005 Feb; 81(2):341-354 [FREE Full text] [Medline: 15699220]
    • (2005) Am J Clin Nutr , vol.81 , Issue.2 , pp. 341-354
    • Cordain, L1    Eaton, SB2    Sebastian, A3    Mann, N4    Lindeberg, S5    Watkins, BA6
  • 2
    • 29144467932 scopus 로고    scopus 로고
    • Protein-bound advanced glycation endproducts (AGEs) as bioactive amino acid derivatives in foods
    • Dec; [doi] [Medline: 15997413]
    • Henle T. Protein-bound advanced glycation endproducts (AGEs) as bioactive amino acid derivatives in foods. Amino Acids 2005 Dec; 29(4):313-322. [doi: 10.1007/s00726-005-0200-2] [Medline: 15997413]
    • (2005) Amino Acids , vol.29 , Issue.4 , pp. 313-322
    • Henle, T.1
  • 3
    • 21444448717 scopus 로고    scopus 로고
    • High-fat diet enhances visceral advanced glycation end products, nuclear O-Glc-Nac modification, p38 mitogen-activated protein kinase activation and apoptosis
    • Jul; [doi] [Medline: 15955132]
    • Li S, Liu Y, Sigmon VK, McCort A, Ren J. High-fat diet enhances visceral advanced glycation end products, nuclear O-Glc-Nac modification, p38 mitogen-activated protein kinase activation and apoptosis. Diabetes Obes Metab 2005 Jul; 7(4):448-454. [doi: 10.1111/j.1463-1326.2004.00387.x] [Medline: 15955132]
    • (2005) Diabetes Obes Metab , vol.7 , Issue.4 , pp. 448-454
    • Li, S1    Liu, Y2    Sigmon, VK3    McCort, A4    Ren, J.5
  • 4
    • 27944496510 scopus 로고    scopus 로고
    • In a type 2 diabetic nephropathy rat model, the improvement of obesity by a low calorie diet reduces oxidative/carbonyl stress and prevents diabetic nephropathy
    • Dec; [FREE Full text] [doi] [Medline: 16188903]
    • Nangaku M, Izuhara Y, Usuda N, Inagi R, Shibata T, Sugiyama S, et al. In a type 2 diabetic nephropathy rat model, the improvement of obesity by a low calorie diet reduces oxidative/carbonyl stress and prevents diabetic nephropathy. Nephrol Dial Transplant 2005 Dec; 20(12):2661-2669 [FREE Full text] [doi: 10.1093/ndt/gfi096] [Medline: 16188903]
    • (2005) Nephrol Dial Transplant , vol.20 , Issue.12 , pp. 2661-2669
    • Nangaku, M1    Izuhara, Y2    Usuda, N3    Inagi, R4    Shibata, T5    Sugiyama, S6
  • 5
    • 77953061313 scopus 로고    scopus 로고
    • Advanced glycation end products in foods and a practical guide to their reduction in the diet
    • Jun; e12 [FREE Full text] [doi] [Medline: 20497781]
    • Uribarri J, Woodruff S, Goodman S, Cai W, Chen X, Pyzik R, et al. Advanced glycation end products in foods and a practical guide to their reduction in the diet. J Am Diet Assoc 2010 Jun; 110(6):911-16.e12 [FREE Full text] [doi: 10.1016/j.jada.2010.03.018] [Medline: 20497781]
    • (2010) J Am Diet Assoc , vol.110 , Issue.6 , pp. 911-916
    • Uribarri, J1    Woodruff, S2    Goodman, S3    Cai, W4    Chen, X5    Pyzik, R6
  • 6
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • May; [Medline: 15111519]
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care 2004 May; 27(5):1047-1053. [Medline: 15111519]
    • (2004) Diabetes Care , vol.27 , Issue.5 , pp. 1047-1053
    • Wild, S1    Roglic, G2    Green, A3    Sicree, R4    King, H.5
  • 7
    • 0036300606 scopus 로고    scopus 로고
    • Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse
    • Jul; [FREE Full text] [Medline: 12086936]
    • Hofmann SM, Dong H, Li Z, Cai W, Altomonte J, Thung SN, et al. Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse. Diabetes 2002 Jul; 51(7):2082-2089 [FREE Full text] [Medline: 12086936]
    • (2002) Diabetes , vol.51 , Issue.7 , pp. 2082-2089
    • Hofmann, SM1    Dong, H2    Li, Z3    Cai, W4    Altomonte, J5    Thung, SN6
  • 8
    • 23644444151 scopus 로고    scopus 로고
    • Insulin resistance and type 2 diabetes in high-fat-fed mice are linked to high glycotoxin intake
    • Aug; [FREE Full text] [Medline: 16046296]
    • Sandu O, Song K, Cai W, Zheng F, Uribarri J, Vlassara H. Insulin resistance and type 2 diabetes in high-fat-fed mice are linked to high glycotoxin intake. Diabetes 2005 Aug; 54(8):2314-2319 [FREE Full text] [Medline: 16046296]
    • (2005) Diabetes , vol.54 , Issue.8 , pp. 2314-2319
    • Sandu, O1    Song, K2    Cai, W3    Zheng, F4    Uribarri, J5    Vlassara, H.6
  • 9
    • 79959797020 scopus 로고    scopus 로고
    • Targeted reduction of advanced glycation improves renal function in obesity
    • Jul; [doi] [Medline: 21412218]
    • Harcourt BE, Sourris KC, Coughlan MT, Walker KZ, Dougherty SL, Andrikopoulos S, et al. Targeted reduction of advanced glycation improves renal function in obesity. Kidney Int 2011 Jul; 80(2):190-198. [doi: 10.1038/ki.2011.57] [Medline: 21412218]
    • (2011) Kidney Int , vol.80 , Issue.2 , pp. 190-198
    • Harcourt, BE1    Sourris, KC2    Coughlan, MT3    Walker, KZ4    Dougherty, SL5    Andrikopoulos, S6
  • 10
    • 33748802532 scopus 로고    scopus 로고
    • Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor
    • Sep 12; [FREE Full text] [doi] [Medline: 16954185]
    • Cai W, He JC, Zhu L, Lu C, Vlassara H. Advanced glycation end product (AGE) receptor 1 suppresses cell oxidant stress and activation signaling via EGF receptor. Proc Natl Acad Sci USA 2006 Sep 12; 103(37):13801-13806 [FREE Full text] [doi: 10.1073/pnas.0600362103] [Medline: 16954185]
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.37 , pp. 13801-13806
    • Cai, W1    He, JC2    Zhu, L3    Lu, C4    Vlassara, H.5
  • 11
    • 80052142793 scopus 로고    scopus 로고
    • Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes: Potential role of AGER1 and SIRT1
    • Jul; [FREE Full text] [doi] [Medline: 21709297]
    • Uribarri J, Cai W, Ramdas M, Goodman S, Pyzik R, Chen X, et al. Restriction of advanced glycation end products improves insulin resistance in human type 2 diabetes: Potential role of AGER1 and SIRT1. Diabetes Care 2011 Jul; 34(7):1610-1616 [FREE Full text] [doi: 10.2337/dc11-0091] [Medline: 21709297]
    • (2011) Diabetes Care , vol.34 , Issue.7 , pp. 1610-1616
    • Uribarri, J1    Cai, W2    Ramdas, M3    Goodman, S4    Pyzik, R5    Chen, X6
  • 12
    • 84892425153 scopus 로고    scopus 로고
    • Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women
    • [doi] [Medline: 23959566]
    • Mark AB, Poulsen MW, Andersen S, Andersen JM, Bak MJ, Ritz C, et al. Consumption of a diet low in advanced glycation end products for 4 weeks improves insulin sensitivity in overweight women. Diabetes Care 2014; 37(1):88-95. [doi: 10.2337/dc13-0842] [Medline: 23959566]
    • (2014) Diabetes Care , vol.37 , Issue.1 , pp. 88-95
    • Mark, AB1    Poulsen, MW2    Andersen, S3    Andersen, JM4    Bak, MJ5    Ritz, C6
  • 13
    • 80053408093 scopus 로고    scopus 로고
    • Advanced glycation end products are direct modulators of β-cell function
    • Oct; [FREE Full text] [doi] [Medline: 21911745]
    • Coughlan MT, Yap FY, Tong DC, Andrikopoulos S, Gasser A, Thallas-Bonke V, et al. Advanced glycation end products are direct modulators of β-cell function. Diabetes 2011 Oct; 60(10):2523-2532 [FREE Full text] [doi: 10.2337/db10-1033] [Medline: 21911745]
    • (2011) Diabetes , vol.60 , Issue.10 , pp. 2523-2532
    • Coughlan, MT1    Yap, FY2    Tong, DC3    Andrikopoulos, S4    Gasser, A5    Thallas-Bonke, V6
  • 14
    • 66649125230 scopus 로고    scopus 로고
    • Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis
    • Jun; [FREE Full text] [doi] [Medline: 19246537]
    • Zhao Z, Zhao C, Zhang XH, Zheng F, Cai W, Vlassara H, et al. Advanced glycation end products inhibit glucose-stimulated insulin secretion through nitric oxide-dependent inhibition of cytochrome c oxidase and adenosine triphosphate synthesis. Endocrinology 2009 Jun; 150(6):2569-2576 [FREE Full text] [doi: 10.1210/en.2008-1342] [Medline: 19246537]
    • (2009) Endocrinology , vol.150 , Issue.6 , pp. 2569-2576
    • Zhao, Z1    Zhao, C2    Zhang, XH3    Zheng, F4    Cai, W5    Vlassara, H6
  • 15
    • 0030456403 scopus 로고    scopus 로고
    • Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction
    • Dec 15; (Pt 3): [Medline: 9003372]
    • Kaneto H, Fujii J, Myint T, Miyazawa N, Islam KN, Kawasaki Y, et al. Reducing sugars trigger oxidative modification and apoptosis in pancreatic beta-cells by provoking oxidative stress through the glycation reaction. Biochem J 1996 Dec 15; 320 ( Pt 3):855-863. [Medline: 9003372]
    • (1996) Biochem J , vol.320 , pp. 855-863
    • Kaneto, H1    Fujii, J2    Myint, T3    Miyazawa, N4    Islam, KN5    Kawasaki, Y6
  • 16
    • 79954630874 scopus 로고    scopus 로고
    • Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes
    • May; [doi] [Medline: 21298413]
    • Forbes JM, Söderlund J, Yap FY, Knip M, Andrikopoulos S, Ilonen J, et al. Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes. Diabetologia 2011 May; 54(5):1032-1042. [doi: 10.1007/s00125-011-2058-z] [Medline: 21298413]
    • (2011) Diabetologia , vol.54 , Issue.5 , pp. 1032-1042
    • Forbes, JM1    Söderlund, J2    Yap, FY3    Knip, M4    Andrikopoulos, S5    Ilonen, J6
  • 17
    • 0037241166 scopus 로고    scopus 로고
    • Body fat content and 25-hydroxyvitamin D levels in healthy women
    • Jan; [doi] [Medline: 12519845]
    • Arunabh S, Pollack S, Yeh J, Aloia JF. Body fat content and 25-hydroxyvitamin D levels in healthy women. J Clin Endocrinol Metab 2003 Jan; 88(1):157-161. [doi: 10.1210/jc.2002-020978] [Medline: 12519845]
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.1 , pp. 157-161
    • Arunabh, S1    Pollack, S2    Yeh, J3    Aloia, JF.4
  • 18
    • 33750144187 scopus 로고    scopus 로고
    • Vitamin D status and its relation to age and body mass index
    • [doi] [Medline: 16900001]
    • Bischof MG, Heinze G, Vierhapper H. Vitamin D status and its relation to age and body mass index. Horm Res 2006; 66(5):211-215. [doi: 10.1159/000094932] [Medline: 16900001]
    • (2006) Horm Res , vol.66 , Issue.5 , pp. 211-215
    • Bischof, MG1    Heinze, G2    Vierhapper, H.3
  • 19
    • 0036789137 scopus 로고    scopus 로고
    • The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
    • Oct; [FREE Full text] [Medline: 12351435]
    • Yu JG, Javorschi S, Hevener AL, Kruszynska YT, Norman RA, Sinha M, et al. The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects. Diabetes 2002 Oct; 51(10):2968-2974 [FREE Full text] [Medline: 12351435]
    • (2002) Diabetes , vol.51 , Issue.10 , pp. 2968-2974
    • Yu, JG1    Javorschi, S2    Hevener, AL3    Kruszynska, YT4    Norman, RA5    Sinha, M6
  • 20
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation
    • Jul; [doi] [Medline: 9686693]
    • Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998 Jul; 15(7):539-553. [doi: 10.1002/(SICI)1096-9136(199807)15:7<539::AID-DIA668>3.0.CO; 2-S] [Medline: 9686693]
    • (1998) Diabet Med , vol.15 , Issue.7 , pp. 539-553
    • Alberti, KG1    Zimmet, PZ.2
  • 21
    • 0042855872 scopus 로고    scopus 로고
    • International physical activity questionnaire: 12-country reliability and validity
    • Aug; [doi] [Medline: 12900694]
    • Craig C, Marshall AL, Sjöström M, Bauman AE, Booth ML, Ainsworth BE, et al. International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc 2003 Aug; 35(8):1381-1395. [doi: 10.1249/01.MSS.0000078924.61453.FB] [Medline: 12900694]
    • (2003) Med Sci Sports Exerc , vol.35 , Issue.8 , pp. 1381-1395
    • Craig, C1    Marshall, AL2    Sjöström, M3    Bauman, AE4    Booth, ML5    Ainsworth, BE6
  • 22
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • May; [FREE Full text] [Medline: 13428781]
    • Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957 May; 226(1):497-509 [FREE Full text] [Medline: 13428781]
    • (1957) J Biol Chem , vol.226 , Issue.1 , pp. 497-509
    • Folch, J1    Lees, M2    Sloane Stanley, GH.3
  • 23
    • 3843063285 scopus 로고    scopus 로고
    • Advanced glycoxidation end products in commonly consumed foods
    • Aug; [doi] [Medline: 15281050]
    • Goldberg T, Cai W, Peppa M, Dardaine V, Baliga BS, Uribarri J, et al. Advanced glycoxidation end products in commonly consumed foods. J Am Diet Assoc 2004 Aug; 104(8):1287-1291. [doi: 10.1016/j.jada.2004.05.214] [Medline: 15281050]
    • (2004) J Am Diet Assoc , vol.104 , Issue.8 , pp. 1287-1291
    • Goldberg, T1    Cai, W2    Peppa, M3    Dardaine, V4    Baliga, BS5    Uribarri, J6
  • 24
    • 84881496313 scopus 로고    scopus 로고
    • Plasma levels of advanced glycation endproducts N-(carboxymethyl)lysine, N-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: The Hoorn and CODAM studies
    • Aug; [doi] [Medline: 23780372]
    • Hanssen NM, Engelen L, Ferreira I, Scheijen JL, Huijberts MS, van Greevenbroek MM, et al. Plasma levels of advanced glycation endproducts N-(carboxymethyl)lysine, N-(carboxyethyl)lysine, and pentosidine are not independently associated with cardiovascular disease in individuals with or without type 2 diabetes: The Hoorn and CODAM studies. J Clin Endocrinol Metab 2013 Aug; 98(8):E1369-E1373. [doi: 10.1210/jc.2013-1068] [Medline: 23780372]
    • (2013) J Clin Endocrinol Metab , vol.98 , Issue.8 , pp. E1369-E1373
    • Hanssen, NM1    Engelen, L2    Ferreira, I3    Scheijen, JL4    Huijberts, MS5    van Greevenbroek, MM6
  • 25
    • 0348049800 scopus 로고    scopus 로고
    • Glycation in food and metabolic transit of dietary AGEs (advanced glycation end-products): Studies on the urinary excretion of pyrraline
    • Dec; (Pt 6): [doi] [Medline: 14641068]
    • Foerster A, Henle T. Glycation in food and metabolic transit of dietary AGEs (advanced glycation end-products): Studies on the urinary excretion of pyrraline. Biochem Soc Trans 2003 Dec; 31(Pt 6):1383-1385. [doi: 10.1042/bst0311383] [Medline: 14641068]
    • (2003) Biochem Soc Trans , vol.31 , pp. 1383-1385
    • Foerster, A1    Henle, T.2
  • 26
    • 77954761943 scopus 로고    scopus 로고
    • Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy
    • Aug; [doi] [Medline: 20463655]
    • Penfold SA, Coughlan MT, Patel SK, Srivastava PM, Sourris KC, Steer D, et al. Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy. Kidney Int 2010 Aug; 78(3):287-295. [doi: 10.1038/ki.2010.134] [Medline: 20463655]
    • (2010) Kidney Int , vol.78 , Issue.3 , pp. 287-295
    • Penfold, SA1    Coughlan, MT2    Patel, SK3    Srivastava, PM4    Sourris, KC5    Steer, D6
  • 27
    • 84962129312 scopus 로고    scopus 로고
    • Factors affecting the decline in incidence of diabetes in the Diabetes Prevention Program Outcomes Study (DPPOS)
    • Diabetes Prevention Program (DPP) Research Group, Mar; [doi] [Medline: 25277389]
    • Diabetes Prevention Program (DPP) Research Group, Hamman RF, Horton E, Barrett-Connor E, Bray GA, Christophi CA, et al. Factors affecting the decline in incidence of diabetes in the Diabetes Prevention Program Outcomes Study (DPPOS). Diabetes 2015 Mar; 64(3):989-998. [doi: 10.2337/db14-0333] [Medline: 25277389]
    • (2015) Diabetes , vol.64 , Issue.3 , pp. 989-998
    • Hamman, RF1    Horton, E2    Barrett-Connor, E3    Bray, GA4    Christophi, CA5
  • 28
    • 84885150414 scopus 로고    scopus 로고
    • Diabetes Australia; [accessed 2015-07-04] [WebCite Cache ID 6ZlPXwePD]
    • Shaw J. Diabetes: The silent pandemic and its impact on Australia.: Diabetes Australia; 2012. URL:http://www. diabetesaustralia.com.au/Documents/DA/What%27s%20New/12.03.14%20Diabetes%20management%20booklet%20FINAL. pdf [accessed 2015-07-04] [WebCite Cache ID 6ZlPXwePD]
    • (2012) Diabetes: The silent pandemic and its impact on Australia
    • Shaw, J.1
  • 29
    • 0141975196 scopus 로고    scopus 로고
    • Cooking attenuates the ability of high-amylose meals to reduce plasma insulin concentrations in rats
    • Oct; [Medline: 13129452]
    • Brown MA, Storlien LH, Brown IL, Higgins JA. Cooking attenuates the ability of high-amylose meals to reduce plasma insulin concentrations in rats. Br J Nutr 2003 Oct; 90(4):823-827. [Medline: 13129452]
    • (2003) Br J Nutr , vol.90 , Issue.4 , pp. 823-827
    • Brown, MA1    Storlien, LH2    Brown, IL3    Higgins, JA.4
  • 30
    • 69449104320 scopus 로고    scopus 로고
    • Influence of sourdough prefermentation, of steam cooking suppression and of decreased sucrose content during wheat flakes processing on the plasma glucose and insulin responses and satiety of healthy subjects
    • Feb; [Medline: 19571157]
    • Lioger D, Fardet A, Foassert P, Davicco M, Mardon J, Gaillard-Martinie B, et al. Influence of sourdough prefermentation, of steam cooking suppression and of decreased sucrose content during wheat flakes processing on the plasma glucose and insulin responses and satiety of healthy subjects. J Am Coll Nutr 2009 Feb; 28(1):30-36. [Medline: 19571157]
    • (2009) J Am Coll Nutr , vol.28 , Issue.1 , pp. 30-36
    • Lioger, D1    Fardet, A2    Foassert, P3    Davicco, M4    Mardon, J5    Gaillard-Martinie, B6
  • 31
    • 0021245819 scopus 로고
    • The effect of cooking upon the blood glucose response to ingested carrots and potatoes
    • [Medline: 6734389]
    • Vaaler S, Hanssen KF, Aagenaes O. The effect of cooking upon the blood glucose response to ingested carrots and potatoes. Diabetes Care 1984; 7(3):221-223. [Medline: 6734389]
    • (1984) Diabetes Care , vol.7 , Issue.3 , pp. 221-223
    • Vaaler, S1    Hanssen, KF2    Aagenaes, O.3
  • 32
    • 77951945549 scopus 로고    scopus 로고
    • A diet based on high-heat-treated foods promotes risk factors for diabetes mellitus and cardiovascular diseases
    • May; [FREE Full text] [doi] [Medline: 20335546]
    • Birlouez-Aragon I, Saavedra G, Tessier FJ, Galinier A, Ait-Ameur L, Lacoste F, et al. A diet based on high-heat-treated foods promotes risk factors for diabetes mellitus and cardiovascular diseases. Am J Clin Nutr 2010 May; 91(5):1220-1226 [FREE Full text] [doi: 10.3945/ajcn.2009.28737] [Medline: 20335546]
    • (2010) Am J Clin Nutr , vol.91 , Issue.5 , pp. 1220-1226
    • Birlouez-Aragon, I1    Saavedra, G2    Tessier, FJ3    Galinier, A4    Ait-Ameur, L5    Lacoste, F6
  • 33
    • 35548952654 scopus 로고    scopus 로고
    • Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats
    • Dec; [doi] [Medline: 17660951]
    • Jia X, Wu L. Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats. Mol Cell Biochem 2007 Dec; 306(1-2):133-139. [doi: 10.1007/s11010-007-9563-x] [Medline: 17660951]
    • (2007) Mol Cell Biochem , vol.306 , Issue.1-2 , pp. 133-139
    • Jia, X1    Wu, L.2
  • 34
    • 33745312600 scopus 로고    scopus 로고
    • Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species
    • May; [FREE Full text] [Medline: 16644685]
    • Riboulet-Chavey A, Pierron A, Durand I, Murdaca J, Giudicelli J, Van OE. Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species. Diabetes 2006 May; 55(5):1289-1299 [FREE Full text] [Medline: 16644685]
    • (2006) Diabetes , vol.55 , Issue.5 , pp. 1289-1299
    • Riboulet-Chavey, A1    Pierron, A2    Durand, I3    Murdaca, J4    Giudicelli, J5    Van, OE.6
  • 35
    • 0035656173 scopus 로고    scopus 로고
    • Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB
    • Dec; [FREE Full text] [Medline: 11723063]
    • Bierhaus A, Schiekofer S, Schwaninger M, Andrassy M, Humpert PM, Chen J, et al. Diabetes-associated sustained activation of the transcription factor nuclear factor-kappaB. Diabetes 2001 Dec; 50(12):2792-2808 [FREE Full text] [Medline: 11723063]
    • (2001) Diabetes , vol.50 , Issue.12 , pp. 2792-2808
    • Bierhaus, A1    Schiekofer, S2    Schwaninger, M3    Andrassy, M4    Humpert, PM5    Chen, J6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.