Moraxella catarrhalis decreases antiviral innate immune responses by down-regulation of TLR3 via inhibition of p53 in human bronchial epithelial cells

FASEB Journal

Volumn 30, Issue 6, 2016, Pages 2426-2434

  Heinrich, Annina ^a   Haarmann, Helge ^b   Zahradnik, Sabrina ^c   Frenzel, Katrin ^c   Schreiber, Frauke ^a   Klassert, Tilman E ^a   Heyl, Kerstin A ^a   Endres, Anne Sophie ^d   Schmidtke, Michaela ^a   Hofmann, Jörg ^c   Slevogt, Hortense ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^d Evangelisches Geriatriezentum Berlin   (Germany)

Author keywords

Bacterial colonization; COPD; Lung cancer; Tumor suppressor; Viral infection

Indexed keywords

BETA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 8; PROTEIN P53; RNA; TOLL LIKE RECEPTOR 3; TLR3 PROTEIN, HUMAN;

ARTICLE; BACTERIAL STRAIN; BRONCHUS MUCOSA; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INNATE IMMUNITY; MOLECULAR INTERACTION; MORAXELLA CATARRHALIS; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RNA INTERFERENCE; VIRUS INFECTION; CELL LINE; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; RHINOVIRUS; VIROLOGY;

CELL LINE; DOWN-REGULATION; EPITHELIAL CELLS; HUMANS; IMMUNITY, INNATE; INFLAMMATION; MORAXELLA (BRANHAMELLA) CATARRHALIS; RHINOVIRUS; RNA INTERFERENCE; TOLL-LIKE RECEPTOR 3; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84973163733     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.201500172R     Document Type: Article

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