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Volumn 25, Issue 6, 2016, Pages 1057-1072

Treatment of collagen-induced arthritis using immune modulatory properties of human mesenchymal stem cells

Author keywords

Immune modulation; Mesenchymal stem cells (MSCs); Regulatory T cells (Tregs); Rheumatoid arthritis (RA)

Indexed keywords

COLLAGEN; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; METHOTREXATE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; CYTOKINE; DNA BINDING PROTEIN; IMMUNOGLOBULIN G; IMMUNOLOGIC FACTOR; TRANSCRIPTION FACTOR; ZFPN1A2 PROTEIN, MOUSE;

EID: 84973149426     PISSN: 09636897     EISSN: 15553892     Source Type: Journal    
DOI: 10.3727/096368915X687949     Document Type: Article
Times cited : (34)

References (45)
  • 1
    • 80052287274 scopus 로고    scopus 로고
    • Helios expression is a marker of T cell activation and proliferation
    • Akimova, T.; Beier, U.H.; Wang, L.; Levine, M.H.; Hancock, W.W. Helios expression is a marker of T cell activation and proliferation. PLoS One 6(8): e24226; 2011.
    • (2011) PLoS One , vol.6 , Issue.8 , pp. e24226
    • Akimova, T.1    Beier, U.H.2    Wang, L.3    Levine, M.H.4    Hancock, W.W.5
  • 2
    • 34247231682 scopus 로고    scopus 로고
    • Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis
    • Augello, A.; Tasso, R.; Negrini, S.M.; Cancedda, R.; Pennesi, G. Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis. Arthritis Rheum. 56(4): 1175-1186; 2007.
    • (2007) Arthritis Rheum. , vol.56 , Issue.4 , pp. 1175-1186
    • Augello, A.1    Tasso, R.2    Negrini, S.M.3    Cancedda, R.4    Pennesi, G.5
  • 5
    • 74549151228 scopus 로고    scopus 로고
    • Flk-1mesenchymal stem cells aggravate collageninduced arthritis by up-regulating interleukin-6
    • Chen, B.; Hu, J.; Liao, L.; Sun, Z.; Han, Q.; Song, Z.; Zhao, RC. Flk-1mesenchymal stem cells aggravate collageninduced arthritis by up-regulating interleukin-6. Clin. Exp. Immunol. 159(3): 292-302; 2010.
    • (2010) Clin. Exp. Immunol. , vol.159 , Issue.3 , pp. 292-302
    • Chen, B.1    Hu, J.2    Liao, L.3    Sun, Z.4    Han, Q.5    Song, Z.6    Zhao, R.C.7
  • 6
    • 54149118562 scopus 로고    scopus 로고
    • Mesenchymal stem cells in arthritic diseases
    • Chen, F. C; Tuan, R.S. Mesenchymal stem cells in arthritic diseases. Arthritis Res. Ther. 10(5): 223; 2008.
    • (2008) Arthritis Res. Ther. , vol.10 , Issue.5 , pp. 223
    • Chen, F.C.1    Tuan, R.S.2
  • 7
    • 84855267258 scopus 로고    scopus 로고
    • Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue-derived mesenchymal stem cell transplantation
    • Choi, E.W.; Shin, I.S.; Park, S.Y.; Park, J.H.; Kim, J.S.; Yoon, E.J.; Kang, S.K.; Ra, J.C.; Hong, S.H. Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue-derived mesenchymal stem cell transplantation. Arthritis Rheum. 64(1): 243-253; 2012.
    • (2012) Arthritis Rheum. , vol.64 , Issue.1 , pp. 243-253
    • Choi, E.W.1    Shin, I.S.2    Park, S.Y.3    Park, J.H.4    Kim, J.S.5    Yoon, E.J.6    Kang, S.K.7    Ra, J.C.8    Hong, S.H.9
  • 10
    • 65549123867 scopus 로고    scopus 로고
    • Natural and adaptive foxp3+ regulatory T cells: More of the same or a division of labor?
    • Curotto de Lafaille, M.A.; Lafaille, J.J. Natural and adaptive foxp3+ regulatory T cells: More of the same or a division of labor? Immunity 30(5): 626-635; 2009.
    • (2009) Immunity , vol.30 , Issue.5 , pp. 626-635
    • Curotto de Lafaille, M.A.1    Lafaille, J.J.2
  • 11
    • 37149005795 scopus 로고    scopus 로고
    • Drug-specific and time-dependent risks of bacterial infection among patients with rheumatoid arthritis who were exposed to tumor necrosis factor alpha antagonists
    • Curtis, J.R.; Xi, J.; Patkar, N.; Xie, A.; Saag, K.G.; Martin, C. Drug-specific and time-dependent risks of bacterial infection among patients with rheumatoid arthritis who were exposed to tumor necrosis factor alpha antagonists. Arthritis Rheum. 56(12): 4226-4227; 2007.
    • (2007) Arthritis Rheum. , vol.56 , Issue.12 , pp. 4226-4227
    • Curtis, J.R.1    Xi, J.2    Patkar, N.3    Xie, A.4    Saag, K.G.5    Martin, C.6
  • 12
    • 0033824164 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Biology and potential clinical uses
    • Deans, R.J.; Moseley, A.B. Mesenchymal stem cells: Biology and potential clinical uses. Exp. Hematol. 28(8): 875-884; 2000.
    • (2000) Exp. Hematol. , vol.28 , Issue.8 , pp. 875-884
    • Deans, R.J.1    Moseley, A.B.2
  • 13
    • 70349580508 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Innovative therapeutic tools for rheumatic diseases
    • Djouad, F.; Bouffi, C.; Ghannam, S.; Noel, D.; Jorgensen, C. Mesenchymal stem cells: Innovative therapeutic tools for rheumatic diseases. Nat. Rev. Rheumatol. 5(7): 392-399; 2009.
    • (2009) Nat. Rev. Rheumatol. , vol.5 , Issue.7 , pp. 392-399
    • Djouad, F.1    Bouffi, C.2    Ghannam, S.3    Noel, D.4    Jorgensen, C.5
  • 15
    • 84892703540 scopus 로고    scopus 로고
    • A comparison of adipose and bone marrow-derived mesenchymal stromal cell secreted factors in the treatment of systemic inflammation
    • Elman, J.S.; Li, M.; Wang, F.; Gimble, J.M.; Parekkadan, B. A comparison of adipose and bone marrow-derived mesenchymal stromal cell secreted factors in the treatment of systemic inflammation. J. Inflamm. (Lond.) 11(1): 1; 2014.
    • (2014) J. Inflamm. (Lond.) , vol.11 , Issue.1 , pp. 1
    • Elman, J.S.1    Li, M.2    Wang, F.3    Gimble, J.M.4    Parekkadan, B.5
  • 16
    • 79960378245 scopus 로고    scopus 로고
    • Allogeneic mesenchymal stem cells: Agents of immune modulation
    • English, K.; Mahon, B.P. Allogeneic mesenchymal stem cells: Agents of immune modulation. J. Cell. Biochem. 112(8): 1963-1968; 2011.
    • (2011) J. Cell. Biochem. , vol.112 , Issue.8 , pp. 1963-1968
    • English, K.1    Mahon, B.P.2
  • 17
    • 65249161683 scopus 로고    scopus 로고
    • Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells
    • Gonzalez, M.A.; Gonzalez-Rey, E.; Rico, L.; Buscher, D.; Delgado, M. Treatment of experimental arthritis by inducing immune tolerance with human adipose-derived mesenchymal stem cells. Arthritis Rheum. 60(4): 1006-1019; 2009.
    • (2009) Arthritis Rheum. , vol.60 , Issue.4 , pp. 1006-1019
    • Gonzalez, M.A.1    Gonzalez-Rey, E.2    Rico, L.3    Buscher, D.4    Delgado, M.5
  • 18
    • 84860425709 scopus 로고    scopus 로고
    • Comparative analysis of paracrine factor expression in human adult mesenchymal stem cells derived from bone marrow, adipose, and dermal tissue
    • Hsiao, S.T.; Asgari, A.; Lokmic, Z.; Sinclair, R.; Dusting, G.J.; Lim, S.Y.; Dilley, R.J. Comparative analysis of paracrine factor expression in human adult mesenchymal stem cells derived from bone marrow, adipose, and dermal tissue. Stem Cells Dev. 21(12): 2189-2203; 2012.
    • (2012) Stem Cells Dev. , vol.21 , Issue.12 , pp. 2189-2203
    • Hsiao, S.T.1    Asgari, A.2    Lokmic, Z.3    Sinclair, R.4    Dusting, G.J.5    Lim, S.Y.6    Dilley, R.J.7
  • 19
    • 84858874884 scopus 로고    scopus 로고
    • B cell targeted therapies: Safety considerations
    • Kavanaugh, A.F. B cell targeted therapies: Safety considerations. J. Rheumatol. Suppl. 77: 18-23; 2006.
    • (2006) J. Rheumatol. Suppl. , vol.77 , pp. 18-23
    • Kavanaugh, A.F.1
  • 20
    • 84863066311 scopus 로고    scopus 로고
    • Isolation of mesenchymal stem cells from the mononuclear cells remaining in the bone marrow processing kit
    • Kim, S.; Heo, J.S.; Kim, H.S.; Kim, H.O. Isolation of mesenchymal stem cells from the mononuclear cells remaining in the bone marrow processing kit. Korean J. Blood Transfus. 21(3): 280-288; 2010.
    • (2010) Korean J. Blood Transfus. , vol.21 , Issue.3 , pp. 280-288
    • Kim, S.1    Heo, J.S.2    Kim, H.S.3    Kim, H.O.4
  • 22
    • 84860238652 scopus 로고    scopus 로고
    • Multipotent mesenchymal stromal cells and the innate immune system
    • Le Blanc, K.; Mougiakakos, D. Multipotent mesenchymal stromal cells and the innate immune system. Nat. Rev. Immunol. 12(5): 383-396; 2012.
    • (2012) Nat. Rev. Immunol. , vol.12 , Issue.5 , pp. 383-396
    • Le Blanc, K.1    Mougiakakos, D.2
  • 23
    • 70449727070 scopus 로고    scopus 로고
    • Bortezomib attenuates murine collagen-induced arthritis
    • Lee, S.W.; Kim, J.H.; Park, Y.B.; Lee, S.K. Bortezomib attenuates murine collagen-induced arthritis. Ann. Rheum. Dis. 68(11): 1761-1767; 2009.
    • (2009) Ann. Rheum. Dis. , vol.68 , Issue.11 , pp. 1761-1767
    • Lee, S.W.1    Kim, J.H.2    Park, Y.B.3    Lee, S.K.4
  • 24
    • 0036886390 scopus 로고    scopus 로고
    • The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells
    • Levings, M.K.; Bacchetta, R.; Schulz, U.; Roncarolo, M.G. The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells. Int. Arch. Allergy Immunol. 129(4): 263-276; 2002.
    • (2002) Int. Arch. Allergy Immunol. , vol.129 , Issue.4 , pp. 263-276
    • Levings, M.K.1    Bacchetta, R.2    Schulz, U.3    Roncarolo, M.G.4
  • 25
    • 84866492475 scopus 로고    scopus 로고
    • Do mesenchymal stem cells function across species barriers? Relevance for xenotransplantation
    • Li, J.; Ezzelarab, M.B.; Cooper, D.K. Do mesenchymal stem cells function across species barriers? Relevance for xenotransplantation. Xenotransplantation 19(5): 273-285; 2012.
    • (2012) Xenotransplantation , vol.19 , Issue.5 , pp. 273-285
    • Li, J.1    Ezzelarab, M.B.2    Cooper, D.K.3
  • 26
    • 77955451557 scopus 로고    scopus 로고
    • Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: A pilot clinical study
    • Liang, J.; Zhang, H.; Hua, B.; Wang, H.; Lu, L.; Shi, S.; Hou, Y.; Zeng, X.; Gilkeson, G.S.; Sun, L. Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: A pilot clinical study. Ann. Rheum. Dis. 69(8): 1423-1429; 2010.
    • (2010) Ann. Rheum. Dis. , vol.69 , Issue.8 , pp. 1423-1429
    • Liang, J.1    Zhang, H.2    Hua, B.3    Wang, H.4    Lu, L.5    Shi, S.6    Hou, Y.7    Zeng, X.8    Gilkeson, G.S.9    Sun, L.10
  • 28
    • 80052338976 scopus 로고    scopus 로고
    • Role of mesenchymal stem cells in reestablishing immunologic tolerance in autoimmune rheumatic diseases
    • MacDonald, G.I.; Augello, A.; De Bari, C. Role of mesenchymal stem cells in reestablishing immunologic tolerance in autoimmune rheumatic diseases. Arthritis Rheum. 63 (9): 2547-2557; 2011.
    • (2011) Arthritis Rheum. , vol.63 , Issue.9 , pp. 2547-2557
    • MacDonald, G.I.1    Augello, A.2    De Bari, C.3
  • 29
    • 78649733250 scopus 로고    scopus 로고
    • Bone marrow and umbilical cord blood human mesenchymal stem cells: State of the art
    • Malgieri, A.; Kantzari, E.; Patrizi, M.P.; Gambardella, S. Bone marrow and umbilical cord blood human mesenchymal stem cells: State of the art. Int. J. Clin. Exp. Med. 3(4): 248-269; 2011.
    • (2011) Int. J. Clin. Exp. Med. , vol.3 , Issue.4 , pp. 248-269
    • Malgieri, A.1    Kantzari, E.2    Patrizi, M.P.3    Gambardella, S.4
  • 31
    • 0025139699 scopus 로고
    • The use of combinations of disease-modifying antirheumatic agents in rheumatoid arthritis
    • Paulus, H.E. The use of combinations of disease-modifying antirheumatic agents in rheumatoid arthritis. Arthritis Rheum. 33(1): 113-120; 1990.
    • (1990) Arthritis Rheum. , vol.33 , Issue.1 , pp. 113-120
    • Paulus, H.E.1
  • 32
    • 0027524471 scopus 로고
    • Protocol development for combination therapy with disease-modifying antirheumatic drugs
    • Paulus, H.E. Protocol development for combination therapy with disease-modifying antirheumatic drugs. Semin. Arthritis Rheum. 23(2 Suppl 1): 19-25; 1993.
    • (1993) Semin. Arthritis Rheum. , vol.23 , pp. 19-25
    • Paulus, H.E.1
  • 33
    • 34548739534 scopus 로고    scopus 로고
    • Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction
    • Prevosto, C.; Zancolli, M.; Canevali, P.; Zocchi, M.R.; Poggi, A. Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction. Haematologica 92(7): 881-888; 2007.
    • (2007) Haematologica , vol.92 , Issue.7 , pp. 881-888
    • Prevosto, C.1    Zancolli, M.2    Canevali, P.3    Zocchi, M.R.4    Poggi, A.5
  • 35
    • 77957196913 scopus 로고    scopus 로고
    • Rheumatoid arthritis
    • Scott, D.; Wolfe, F.; Huizinga, T.W. Rheumatoid arthritis. Lancet 376(9746): 1094-1108; 2010.
    • (2010) Lancet , vol.376 , Issue.9746 , pp. 1094-1108
    • Scott, D.1    Wolfe, F.2    Huizinga, T.W.3
  • 36
    • 0028226403 scopus 로고
    • Low-dose methotrexate in rheumatic diseases--Efficacy, side effects, and risk factors for side effects
    • Schnabel, A.; Gross, W.L. Low-dose methotrexate in rheumatic diseases--Efficacy, side effects, and risk factors for side effects. Semin. Arthritis Rheum. 23(5): 310-327; 1994.
    • (1994) Semin. Arthritis Rheum. , vol.23 , Issue.5 , pp. 310-327
    • Schnabel, A.1    Gross, W.L.2
  • 37
    • 77649298684 scopus 로고    scopus 로고
    • Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen induced arthritis
    • Schurgers, E.; Kelchtermans, H.; Mitera, T.; Geboes, L.; Matthys, P. Discrepancy between the in vitro and in vivo effects of murine mesenchymal stem cells on T-cell proliferation and collagen induced arthritis. Arthritis Res. Ther. 12(1): R31; 2010.
    • (2010) Arthritis Res. Ther. , vol.12 , Issue.1 , pp. R31
    • Schurgers, E.1    Kelchtermans, H.2    Mitera, T.3    Geboes, L.4    Matthys, P.5
  • 38
    • 33846415475 scopus 로고    scopus 로고
    • Standardization of immunohistochemistry for formalin-fixed, paraffin-embedded tissue sections based on the antigen-retrieval technique: From experiments to hypothesis
    • Shi, S.R.; Liu, C.; Taylor, C.R. Standardization of immunohistochemistry for formalin-fixed, paraffin-embedded tissue sections based on the antigen-retrieval technique: From experiments to hypothesis. J. Histochem. Cytochem. 55(2): 105-109; 2007.
    • (2007) J. Histochem. Cytochem. , vol.55 , Issue.2 , pp. 105-109
    • Shi, S.R.1    Liu, C.2    Taylor, C.R.3
  • 40
    • 84875756240 scopus 로고    scopus 로고
    • Duration of in vitro storage affects the key stem cell features of human bone marrow-derived mesenchymal stromal cells for clinical transplantation
    • Sohn, H.S.; Heo, J.S.; Kim, H.S.; Choi, Y.; Kim, H.O. Duration of in vitro storage affects the key stem cell features of human bone marrow-derived mesenchymal stromal cells for clinical transplantation. Cytotherapy 15(4): 460-466; 2013.
    • (2013) Cytotherapy , vol.15 , Issue.4 , pp. 460-466
    • Sohn, H.S.1    Heo, J.S.2    Kim, H.S.3    Choi, Y.4    Kim, H.O.5
  • 41
    • 33645023639 scopus 로고    scopus 로고
    • Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: The role of T regulatory cells
    • Taylor, A.; Verhagen, J.; Blaser, K.; Akdis, M.; Akdis, C.A. Mechanisms of immune suppression by interleukin-10 and transforming growth factor-beta: The role of T regulatory cells. Immunology 117(4): 433-442; 2006.
    • (2006) Immunology , vol.117 , Issue.4 , pp. 433-442
    • Taylor, A.1    Verhagen, J.2    Blaser, K.3    Akdis, M.4    Akdis, C.A.5
  • 42
    • 77951638740 scopus 로고    scopus 로고
    • Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells
    • Thornton, A.M.; Korty, P.E.; Tran, D.Q.; Wohlfert, E.A.; Murray, P.E.; Belkaid, Y.; Shevach, E.M. Expression of Helios, an Ikaros transcription factor family member, differentiates thymic-derived from peripherally induced Foxp3+ T regulatory cells. J. Immunol. 184(7): 3433-3441; 2010.
    • (2010) J. Immunol. , vol.184 , Issue.7 , pp. 3433-3441
    • Thornton, A.M.1    Korty, P.E.2    Tran, D.Q.3    Wohlfert, E.A.4    Murray, P.E.5    Belkaid, Y.6    Shevach, E.M.7
  • 43
    • 79958070185 scopus 로고    scopus 로고
    • Mesenchymal-stem-cell-based experimental and clinical trials: Current status and open questions
    • Wang, J.; Liao, L.; Tan, J. Mesenchymal-stem-cell-based experimental and clinical trials: current status and open questions. Expert Opin. Biol. Ther. 11(7): 893-909; 2011.
    • (2011) Expert Opin. Biol. Ther. , vol.11 , Issue.7 , pp. 893-909
    • Wang, J.1    Liao, L.2    Tan, J.3
  • 45
    • 77952923309 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stromal cells and their therapeutic consequences for immune-mediated disorders
    • Zhao, S.; Wehner, R.; Bornhauser, M.; Wassmuth, R.; Bachmann, M.; Schmitz, M. Immunomodulatory properties of mesenchymal stromal cells and their therapeutic consequences for immune-mediated disorders. Stem Cells Dev. 19(5): 607-614; 2010.
    • (2010) Stem Cells Dev. , vol.19 , Issue.5 , pp. 607-614
    • Zhao, S.1    Wehner, R.2    Bornhauser, M.3    Wassmuth, R.4    Bachmann, M.5    Schmitz, M.6


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