Specific Features of Subjective Cognitive Decline Predict Faster Conversion to Mild Cognitive Impairment

Journal of Alzheimer's Disease

Volumn 52, Issue 1, 2016, Pages 271-281

  Fernández Blázquez, Miguel A ^a   Ávila Villanueva, Marina ^a   Maestú, Fernando ^b   Medina, Miguel ^a,c  

^a Instituto de Salud Carlos III   (Spain)

^b UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA EN RED SOBRE ENFERMEDADES NEURODEGENERATIVAS CIBERNED   (Spain)

Author keywords

Aging Alzheimer's disease; cognitive symptoms; dementia; mild cognitive impairment; subjective cognitive decline 2016 IOS Press and the authors. All rights reserved.

Indexed keywords

APOLIPOPROTEIN E4; BIOLOGICAL MARKER;

AGED; ALZHEIMER DISEASE; ARTICLE; ASSESSMENT OF HUMANS; CLINICAL DEMENTIA RATING; CLOCK DRAWING TEST; COMPARATIVE STUDY; CONTROLLED STUDY; DIGIT SYMBOL CODING; FEMALE; FOLLOW UP; FREE AND CUED SELECTIVE REMINDING TEST; FUNCTIONAL ACTIVITIES QUESTIONNAIRE; HUMAN; LEXICAL AND SEMANTIC VERBAL FLUENCY; MAJOR CLINICAL STUDY; MALE; MENTAL DETERIORATION; MILD COGNITIVE IMPAIRMENT; MINI MENTAL STATE EXAMINATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; REY OSTERRIETH COMPLEX FIGURE TEST; RISK FACTOR; SUBJECTIVE COGNITIVE DECLINE; COGNITIVE DYSFUNCTION; DISEASE COURSE; GENETICS; GENOTYPING TECHNIQUE; KAPLAN MEIER METHOD; NEUROPSYCHOLOGICAL TEST; PERCEPTION; PRODROMAL SYMPTOM; PROGNOSIS; PSYCHOLOGY; TIME FACTOR;

AGED; ALZHEIMER DISEASE; APOLIPOPROTEIN E4; COGNITIVE DYSFUNCTION; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GENOTYPING TECHNIQUES; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; NEUROPSYCHOLOGICAL TESTS; PERCEPTION; PRODROMAL SYMPTOMS; PROGNOSIS; PROSPECTIVE STUDIES; TIME FACTORS;

EID: 84973110340     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-150956     Document Type: Article

References (51)

1. Sperling R, Aisen PS, Beckett L, Bennett D, Craft S, Fagan AM, Iwatsubo T, Jack CR, Kaye J, Montine TJ, Park DC, Reiman EM, Rowe CC, Siemers E, Stern Y, Yaffe K, Carrillo MC, Thies B, Morrison-Bogorad M, Wagster MV, Phelps CH (2011) Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging and the Alzheimer's Association workgroup. Alzheimers Dement 7, 280-292
2. Albert MS, Dekosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, Gamst A, Holtzman DM, Jagust WJ, Petersen RC, Snyder PJ, Carrillo MC, Thies B, PhelpsCH(2011) The diagnosis of mild cognitive impairment due to Alzheimer's disease: Recommendations from the National Institute on Aging and Alzheimer's Associationworkgroup. Alzheimers Dement 7, 270-279
3. McKhann GM, Knopman DS, Chertkow H, Hyman BT, Jack CR, Kawas CH, Klunk WE, Koroshetz WJ, Manly JJ, Mayeux R, Mohs RC, Morris JC, Rossor MN, Scheltens P, Carrillo MC, Thies B, Weintraub S, Phelps CH (2011) The diagnosis of dementia due to Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 7, 263-269
4. Selkoe DJ (2011) Resolving controversies on the path to Alzheimer's therapeutics. Nat Med 17, 1060-1065
5. Hampel H, Lista S, Teipel SJ, Garaci F, Nistico R, Blennow K, Zetterberg H, Bertram L, Duyckaerts C, Bakardjian H, Drzezga A, Colliot O, Epelbaum S, Broich K, Lehéricy S, Brice A, Khachaturian ZS, Aisen PS, Dubois B (2014) Perspective on future role of biological markers in clinical therapy trials of Alzheimer's disease: A long-range point of view beyond 2020. Biochem Pharmacol 88, 426-449
6. Bateman RJ, Xiong C, Benzinger TLS, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, Aisen PS, Ghetti B, Klunk WE, McDade E, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Schofield PR, Sperling RA, Salloway S, Morris JC (2012) Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med 367, 795-804
7. Hampel H, Frank R, Broich K, Teipel SJ, Katz RG, Hardy J, Herholz K, BokdeALW, Jessen F, Hoessler YC, SanhaiWR, Zetterberg H, Woodcock J, Blennow K (2010) Biomarkers for Alzheimer's disease: Academic, industry and regulatory perspectives. Nat Rev Drug Discov 9, 560-574
8. Jessen F (2014) Subjective and objective cognitive decline at the pre-dementia stage of Alzheimer's disease. Eur Arch Psychiatry Clin Neurosci 264, 3-7
9. Rami L, Fortea J, Bosch B, Solé-Padullés C, LladóA, Iranzo A, Sánchez-Valle R, Molinuevo JL (2011) Cerebrospinal fluid biomarkers and memory present distinct associations along the continuum from healthy subjects to AD patients. J Alzheimers Dis 23, 319-326
10. Scheef L, Spottke A, Daerr M, Joe A, Striepens N, Kölsch H, Popp J, Daamen M, Psych D, Gorris D, Heneka MT, Boecker H, Biersack HJ, Maier W, Schild HH, Wagner M, Jessen F (2012) Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment. Neurology 79, 1332-1339
11. Wang Y, Risacher SL,West JD, McDonald BC, Magee TR, Farlow MR, Gao S, O'Neill DP, Saykin AJ (2013) Altered default mode network connectivity in older adults with cognitive complaints and amnestic mild cognitive impairment. J Alzheimers Dis 35, 751-760
12. Dufouil C, Fuhrer R, Alpérovitch A (2005) Subjective cognitive complaints and cognitive decline: Consequence or predictor? The epidemiology of vascular aging study. J Am Geriatr Soc 53, 616-621
13. Glodzik-Sobanska L, Reisberg B, De Santi S, Babb JS, Pirraglia E, Rich KE, Brys M, De Leon MJ (2007) Subjective memory complaints: Presence, severity and future outcome in normal older subjects. Dement Geriatr Cogn Disord 24, 177-184
14. Reisberg B, Shulman MB, Torossian C, Leng L, Zhu W (2010) Outcome over seven years of healthy adults with and without subjective cognitive impairment. Alzheimers Dement 6, 11-24
15. Van Harten AC, Visser PJ, Pijnenburg YAL, Teunissen CE, Blankenstein MA, Scheltens P, Van Flier WM (2013) Cerebrospinal fluid A42 is the best predictor of clinical progression in patients with subjective complaints. Alzheimers Dement 9, 481-487
16. Schmand B, Jonker C, Hooijer C, Lindeboom J (1996) Subjective memory complaints may announce dementia. Neurology 46, 121-125
17. Visser PJ, Verhey F, Knol DL, Scheltens P, Wahlund L-O, Freund-Levi Y, Tsolaki M, Minthon L,Wallin AK, Hampel H, Bürger K, Pirttila T, Soininen H, Rikkert MO, Verbeek MM, Spiru L, Blennow K (2009) Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: A prospective cohort study. Lancet Neurol 8, 619-627
18. Jessen F, Amariglio RE, van Boxtel M, Breteler M, Ceccaldi M, Chételat G, Dubois B, Dufouil C, Ellis KA, Flier WM, Glodzik L, van Harten AC, Leon MJ, McHugh P, Mielke MM, Molinuevo JL, Mosconi L, Osorio RS, Perrotin A, Petersen RC, Rabin LA, Rami L, Reisberg B, Rentz DM, Sachdev PS, de la Sayette V, Saykin AJ, Scheltens P, Shulman MB, Slavin MJ, Sperling RA, Stewart R, Uspenskaya O, Vellas B, Visser PJ,WagnerM(2014) A conceptual framework for research on subjective cognitive decline in preclinical Alzheimer's disease. Alzheimers Dement 10, 844-852
19. Olazarań J, Valentí M, Frades B, Zea-Sevilla MA, Ávila-Villanueva M, Fernández-Blázquez MA, Calero M, Dobato JL, Hernández-Tamames JA, León-Salas B, Agüera-Ortiz L, López-Álvarez J, Larranãga P, Bielza C, Álvarez-Linera J, Martínez-Martín P (2015) The Vallecas Project: A cohort to identify early markers and mechanisms of Alzheimer's disease. Front Aging Neurosci 7, 181
20. FolsteinMF, Folstein SE, McHugh PR (1975) "Mini-mental state": A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12, 189-198
21. Rey A (1941) L'examen psychologique dans les cas d'encéphalopathie traumatique. Arch Psychol (Geneve) 28, 215-285
22. Osterrieth PA(1944) Le test de copie d'une figure complexe; contribution a l'étude de la perception et de la mémoire. / Test of copying a complex figure; contribution to the study of perception and memory. Arch Psychol (Geneve) 30, 206-355
23. Penã-Casanova J, Gramunt-Fombuena N, Quinõnes-Úbeda S, Sánchez-Benavides G, Aguilar M, Badenes D, Molinuevo JL, Robles A, Barquero MS, Payno M, Antúnez C, Martínez-Parra C, Frank-García A, Fernández M, Alfonso V, Sol JM, Blesa R (2009) Spanish multicenter normative studies (NEURONORMA project): Norms for the Rey-Osterrieth complex figure (copy and memory), and free and cued selective reminding test. Arch Clin Neuropsychol 24, 371-393
24. Buschke H (1984) Cued recall in amnesia. J Clin Neuropsychol 6, 433-440
25. Grober E, Buschke H (1987) Genuine memory deficits in dementia. Dev Neuropsychol 3, 13-36
26. Peña-Casanova J, Quiñones-Ubeda S, Gramunt-Fombuena N, Quintana-Aparicio M, Aguilar M, Badenes D, Cerulla N, Molinuevo JL, Ruiz E, Robles A, Barquero MS, Antúnez C, Martínez-Parra C, Frank-García A, Fernández M, Alfonso V, Sol JM, Blesa R (2009) Spanish Multicenter Normative Studies (NEURONORMA Project): Norms for verbal fluency tests. Arch Clin Neuropsychol 24, 395-411
27. Cacho J, García-García R, Arcaya J, Vicente JL, Lantada N (1999) A proposal for application and scoring of the Clock Drawing Test in Alzheimer's disease. Rev Neurol 28, 648-655
28. Wechsler D (1997) Wechsler Adult Intelligence Scale-III, The Psychological Corporation, San Antonio
29. Pfeffer RI, Kurosaki TT, Harrah CH, Chance JM, Filos S (1982) Measurement of functional activities in older adults in the community. J Gerontol 37, 323-329
30. Hughes CP, Berg L, Danziger WL (1982) A new clinical scale for the staging of dementia. Br J Psychiatry 140, 566-572
31. Yesavage JA, Brink TL, Rose TL, Lum O, Huang V, Adey M, Leirer VO (1983) Development and validation of a geriatric depression screening scale: A preliminary report. J Psychiatr Res 17, 37-49
32. Spielberger C, Gorsuch R, Leshene R (1970) Manual for the State-Trait Anxiety Inventory, Consulting Psychologists Press, Palo Alto, CA
33. Calero O, Hortigüela R, Bullido MJ, Calero M (2009) Apolipoprotein E genotyping method by Real Time PCR, a fast and cost-effective alternative to the TaqMan® and FRET assays. J Neurosci Methods 183, 238-240
34. R Development Core Team (2008) R: A Language and Environment for Statistical Computing, R Foundation for Statistical Computing, Vienna
35. Jonker C, Geerlings MI, Schmand B (2000) Are memory complaints predictive for dementia? A review of clinical and population-based studies. Int J Geriatr Psychiatry 15, 983-991
36. Amariglio RE, Townsend MK, Grodstein F, Sperling RA, Rentz DM (2011) Specific subjective memory complaints in older persons may indicate poor cognitive function. J Am Geriatr Soc 59, 1612-1617
37. Sachdev PS, Brodaty H, Reppermund S, Kochan NA, Trollor JN, Draper B, Slavin MJ, Crawford J, Kang K, Broe GA, Mather KA, LuxO(2010) The Sydney Memory and Ageing Study (MAS): Methodology and baseline medical and neuropsychiatric characteristics of an elderly epidemiological non-demented cohort of Australians aged 70-90 years. Int Psychogeriatr 22, 1248-1264
38. Raber J, Huang Y, Ashford JW (2004) APOE genotype accounts for the vast majority ofADrisk andADpathology. Neurobiol Aging 25, 641-650
39. Comijs HC, Deeg DJ, Dik MG, Twisk JW, Jonker C (2002) Memory complaints; the association with psycho-affective and health problems and the role of personality characteristics. A 6-year follow-up study. J Affect Disord 72, 157-165
40. Reisberg B, Gauthier S (2008) Current evidence for subjective cognitive impairment (SCI) as the pre-mild cognitive impairment (MCI) stage of subsequently manifest Alzheimer's disease. Int Psychogeriatr 20, 1-16
41. Montejo P, Montenegro M, Fernández-Blázquez MA, Turrero-Nogués A, Yubero R, Huertas E, Maestú F (2014) Association of perceived health and depression with older adults' subjective memory complaints: Contrasting a specific questionnaire with general complaints questions. Eur J Ageing 11, 77-87
42. Yates JA, Clare L, Woods RT, Matthews FE (2015) Subjective memory complaints are involved in the relationship between mood and mild cognitive impairment. J Alzheimers Dis 48(Suppl 1), S115-S123
43. Mourao RJ, Mansur G, Malloy-Diniz LF, Castro Costa E, Diniz BS (2015) Depressive symptoms increase the risk of progression to dementia in subjects with mild cognitive impairment: Systematic review and meta-analysis. Int J Geriatr Psychiatry. doi: 10.1002/gps.4406 [epubs ahead of print]
44. Cooper C, Sommerlad A, Lyketsos CG, Livingston G (2015) Modifiable predictors of dementia in mild cognitive impairment: A systematic review and meta-analysis. Am J Psychiatry 172, 323-334
45. Li J-Q, Tan L,Wang H-F, Tan M-S, Tan L, XuW, Zhao Q-F, Wang J, Jiang T, Yu J-T (2015) Risk factors for predicting progression from mild cognitive impairment to Alzheimer's disease: A systematic review and meta-analysis of cohort studies. J Neurol Neurosurg Psychiatry. doi: 10.1136/jnnp-2014-310095 [epubs ahead of print]
46. Mitchell AJ, Beaumont H, Ferguson D, Yadegarfar M, Stubbs B (2014) Risk of dementia and mild cognitive impairment in older people with subjective memory complaints: Meta-analysis. Acta Psychiatr Scand 130, 439-451
47. Fonseca JAS, Ducksbury R, Rodda J, Whitfield T, Nagaraj C, Suresh K, Stevens T, Walker Z (2015) Factors that predict cognitive decline in patients with subjective cognitive impairment. Int Psychogeriatr 27, 1671-1677
48. Jessen F,Wiese B, Cvetanovska G, Fuchs A, Kaduszkiewicz H, Kölsch H, Luck T, Mösch E, Pentzek M, Riedel-Heller SG, Werle J, Weyerer S, Zimmermann T, Maier W, Bickel H (2007) Patterns of subjective memory impairment in the elderly: Association with memory performance. Psychol Med 37, 1753-1762
49. Montejo P, Montenegro M, FernandezMA,Maestu F (2011) Subjective memory complaints in the elderly: Prevalence and influence of temporal orientation, depression and quality of life in a population-based study in the city of Madrid. Aging Ment Health 15, 85-96
50. Geerlings MI, Jonker C, Bouter LM, Ader HJ, Schmand B (1999) Association between memory complaints and incident Alzheimer's disease in elderly people with normal baseline cognition. Am J Psychiatry 156, 531-537
51. van Oijen M, de Jong FJ, Hofman A, Koudstaal PJ, Breteler MMB (2007) Subjective memory complaints, education, and risk of Alzheimer's disease. Alzheimers Dement 3, 92-97