Composite Hydrogels with Tunable Anisotropic Morphologies and Mechanical Properties

Chemistry of Materials

Volumn 28, Issue 10, 2016, Pages 3406-3415

  Chau, Mokit ^a   De France, Kevin J ^b   Kopera, Bernd ^a,c   Machado, Vanessa R ^a   Rosenfeldt, Sabine ^c   Reyes, Laura ^a   Chan, Katelyn J W ^b   Förster, Stephan ^c   Cranston, Emily D ^b   Hoare, Todd ^b   Kumacheva, Eugenia ^a,d  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

^c UNIVERSITY OF BAYREUTH   (Germany)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AEROGELS; ANISOTROPY; BIOCOMPATIBILITY; CELLULOSE DERIVATIVES; MORPHOLOGY; TISSUE ENGINEERING; X RAY SCATTERING;

ANISOTROPIC HYDROGELS; CELLULOSE NANOCRYSTAL (CNCS); COMPOSITE HYDROGELS; CONTROLLABLE MORPHOLOGY; MECHANICAL INTEGRITY; OLIGOETHYLENE GLYCOLS; ORTHOGONAL DIRECTIONS; STRUCTURE AND PROPERTIES;

HYDROGELS;

ANISOTROPY; COMPOSITES; CROSS LINKING; FREEZE DRYING; GELS;

EID: 84973109387     PISSN: 08974756     EISSN: 15205002     Source Type: Journal    
DOI: 10.1021/acs.chemmater.6b00792     Document Type: Article

References (74)

1. Hoare, T. R.; Kohane, D. S. Hydrogels in Drug Delivery: Progress and Challenges Polymer 2008, 49, 1993-2007 10.1016/j.polymer.2008.01.027
2. Hoffman, A. S. Hydrogels for Biomedical Applications Adv. Drug Delivery Rev. 2002, 54, 3-12 10.1016/S0169-409X(01)00239-3
3. Khademhosseini, A.; Vacanti, J. P.; Langer, R. Progress in Tissue Engineering Sci. Am. 2009, 300, 64-71 10.1038/scientificamerican0509-64
4. Kim, J. J.; Park, K. Smart Hydrogels for Bioseparation Bioseparation 1998, 7, 177-184 10.1023/A:1008050124949
5. Jing, G.; Wang, L.; Yu, H.; Amer, W. a.; Zhang, L. Recent Progress on Study of Hybrid Hydrogels for Water Treatment Colloids Surf., A 2013, 416, 86-94 10.1016/j.colsurfa.2012.09.043
6. Haque, M. A.; Kurokawa, T.; Gong, J. P. Anisotropic Hydrogel Based on Bilayers: Color, Strength, Toughness, and Fatigue Resistance Soft Matter 2012, 8, 8008-8016 10.1039/c2sm25670c
7. Walker, K. J.; Madihally, S. V. Anisotropic Temperature Sensitive Chitosan-Based Injectable Hydrogels Mimicking Cartilage Matrix J. Biomed. Mater. Res., Part B 2015, 103, 1149-1160 10.1002/jbm.b.33293
8. Rudisill, S. G.; DiVito, M. D.; Hubel, A.; Stein, A. In Vitro Collagen Fibril Alignment via Incorporation of Nanocrystalline Cellulose Acta Biomater. 2015, 12, 122-128 10.1016/j.actbio.2014.10.024
9. Aubin, H.; Nichol, J. W.; Hutson, C. B.; Bae, H.; Sieminski, A. L.; Cropek, D. M.; Akhyari, P.; Khademhosseini, A. Directed 3D Cell Alignment and Elongation in Microengineered Hydrogels Biomaterials 2010, 31, 6941-6951 10.1016/j.biomaterials.2010.05.056
10. Yamada, M.; Sugaya, S.; Naganuma, Y.; Seki, M. Microfluidic Synthesis of Chemically and Physically Anisotropic Hydrogel Microfibers for Guided Cell Growth and Networking Soft Matter 2012, 8, 3122-3130 10.1039/c2sm07263g
11. Li, Y.; Huang, G.; Zhang, X.; Wang, L.; Du, Y.; Lu, T. J.; Xu, F. Engineering Cell Alignment in Vitro Biotechnol. Adv. 2014, 32, 347-365 10.1016/j.biotechadv.2013.11.007
12. Camarero-Espinosa, S.; Rothen-Rutishauser, B.; Weder, C.; Foster, E. J. Directed Cell Growth in Multi-Zonal Scaffolds for Cartilage Tissue Engineering Biomaterials 2016, 74, 42-52 10.1016/j.biomaterials.2015.09.033
13. Swan, M. C.; Bucknall, D. G.; Goodacre, T. E. E.; Czernuszka, J. T. Synthesis and Properties of a Novel Anisotropic Self-Inflating Hydrogel Tissue Expander Acta Biomater. 2011, 7, 1126-1132 10.1016/j.actbio.2010.10.017
14. Tseng, H.; Puperi, D. S.; Kim, E. J.; Ayoub, S.; Shah, J. V.; Cuchiara, M. L.; West, J. L.; Grande-Allen, K. J. Anisotropic Poly(ethylene Glycol)/polycaprolactone Hydrogel-Fiber Composites for Heart Valve Tissue Engineering Tissue Eng., Part A 2014, 20, 2634-2645 10.1089/ten.tea.2013.0397
15. Voge, C. M.; Kariolis, M.; MacDonald, R. A.; Stegemann, J. P. Directional Conductivity in SWNT-Collagen-Fibrin Composite Biomaterials through Strain-Induced Matrix Alignment J. Biomed. Mater. Res., Part A 2008, 86A, 269-277 10.1002/jbm.a.32029
16. Dvir, T.; Timko, B. P.; Brigham, M. D.; Naik, S. R.; Karajanagi, S. S.; Levy, O.; Jin, H.; Parker, K. K.; Langer, R.; Kohane, D. S. Nanowired Three-Dimensional Cardiac Patches Nat. Nanotechnol. 2011, 6, 720-725 10.1038/nnano.2011.160
17. Ahadian, S.; Ramón-Azcón, J.; Estili, M.; Liang, X.; Ostrovidov, S.; Shiku, H.; Ramalingam, M.; Nakajima, K.; Sakka, Y.; Bae, H. et al. Hybrid Hydrogels Containing Vertically Aligned Carbon Nanotubes with Anisotropic Electrical Conductivity for Muscle Myofiber Fabrication Sci. Rep. 2014, 4, 4271 10.1038/srep04271
18. Barrow, M.; Zhang, H. Aligned Porous Stimuli-Responsive Hydrogels via Directional Freezing and Frozen {UV} Initiated Polymerization Soft Matter 2013, 9, 2723-2729 10.1039/c2sm27722k
19. Mao, M.; He, J.; Liu, Y.; Li, X.; Li, D. Ice-Template-Induced Silk Fibroin-Chitosan Scaffolds with Predefined Microfluidic Channels and Fully Porous Structures Acta Biomater. 2012, 8, 2175-2184 10.1016/j.actbio.2011.12.025
20. Chen, M.; Zhu, J.; Qi, G.; He, C.; Wang, H. Anisotropic Hydrogels Fabricated with Directional Freezing and Radiation-Induced Polymerization and Crosslinking Method Mater. Lett. 2012, 89, 104-107 10.1016/j.matlet.2012.08.087
21. Zhu, J.; Wang, J.; Liu, Q.; Liu, Y.; Wang, L.; He, C.; Wang, H. Anisotropic Tough poly(2-Hydroxyethyl Methacrylate) Hydrogels Fabricated by Directional Freezing Redox Polymerization J. Mater. Chem. B 2013, 1, 978-986 10.1039/C2TB00288D
22. Paz, A. C.; Soleas, J.; Poon, J. C. H.; Trieu, D.; Waddell, T. K.; McGuigan, A. P. Challenges and Opportunities for Tissue-Engineering Polarized Epithelium Tissue Eng., Part B 2014, 20, 56-72 10.1089/ten.teb.2013.0144
23. Engler, A. J.; Sen, S.; Sweeney, H. L.; Discher, D. E. Matrix Elasticity Directs Stem Cell Lineage Specification Cell 2006, 126, 677-689 10.1016/j.cell.2006.06.044
24. He, J.; Wang, Y.; Liu, Y.; Li, D.; Jin, Z. Layer-by-Layer Micromolding of Natural Biopolymer Scaffolds with Intrinsic Microfluidic Networks Biofabrication 2013, 5, 025002 10.1088/1758-5082/5/2/025002
25. He, J.; Mao, M.; Liu, Y.; Zhu, L.; Li, D. Bottom-up Fabrication of 3D Cell-Laden Microfluidic Constructs Mater. Lett. 2013, 90, 93-96 10.1016/j.matlet.2012.09.024
26. Barrow, M.; Eltmimi, A.; Ahmed, A.; Myers, P.; Zhang, H. Frozen Polymerization for Aligned Porous Structures with Enhanced Mechanical Stability, Conductivity, and as Stationary Phase for HPLC J. Mater. Chem. 2012, 22, 11615-11620 10.1039/c2jm31425h
27. Wu, Z. L.; Gong, J. P. Hydrogels with Self-Assembling Ordered Structures and Their Functions NPG Asia Mater. 2011, 3, 57-64 10.1038/asiamat.2010.200
28. Chatelin, S.; Bernal, M.; Deffieux, T.; Papadacci, C.; Flaud, P.; Nahas, A.; Boccara, C.; Gennisson, J.-L.; Tanter, M.; Pernot, M. Anisotropic Polyvinyl Alcohol Hydrogel Phantom for Shear Wave Elastography in Fibrous Biological Soft Tissue: A Multimodality Characterization Phys. Med. Biol. 2014, 59, 6923-6940 10.1088/0031-9155/59/22/6923
29. Osorio-Madrazo, A.; Eder, M.; Rueggeberg, M.; Pandey, J. K.; Harrington, M. J.; Nishiyama, Y.; Putaux, J.-L.; Rochas, C.; Burgert, I. Reorientation of Cellulose Nanowhiskers in Agarose Hydrogels under Tensile Loading Biomacromolecules 2012, 13, 850-856 10.1021/bm201764y
30. Zhang, S.; Greenfield, M. a; Mata, A.; Palmer, L. C.; Bitton, R.; Mantei, J. R.; Aparicio, C.; de la Cruz, M. O.; Stupp, S. I. A Self-Assembly Pathway to Aligned Monodomain Gels Nat. Mater. 2010, 9, 594-601 10.1038/nmat2778
31. Yang, W.; Furukawa, H.; Gong, J. P. Highly Extensible Double-Network Gels with Self-Assembling Anisotropic Structure Adv. Mater. 2008, 20, 4499-4503 10.1002/adma.200801396
32. Haque, M. A.; Kamita, G.; Kurokawa, T.; Tsujii, K.; Gong, J. P. Unidirectional Alignment of Lamellar Bilayer in Hydrogel: One-Dimensional Swelling, Anisotropic Modulus, and Stress/Strain Tunable Structural Color Adv. Mater. 2010, 22, 5110-5114 10.1002/adma.201002509
33. Pei, X.; Zan, T.; Li, H.; Chen, Y.; Shi, L.; Zhang, Z. Pure Anisotropic Hydrogel with an Inherent Chiral Internal Structure Based on the Chiral Nematic Liquid Crystal Phase of Rodlike Viruses ACS Macro Lett. 2015, 4, 1215-1219 10.1021/acsmacrolett.5b00677
34. Hockaday, L. A.; Kang, K. H.; Colangelo, N. W.; Cheung, P. Y. C.; Duan, B.; Malone, E.; Wu, J.; Girardi, L. N.; Bonassar, L. J.; Lipson, H. et al. Rapid 3D Printing of Anatomically Accurate and Mechanically Heterogeneous Aortic Valve Hydrogel Scaffolds Biofabrication 2012, 4, 035005 10.1088/1758-5082/4/3/035005
35. Barrow, M.; Zhang, H. Aligned Porous Stimuli-Responsive Hydrogels via Directional Freezing and Frozen UV Initiated Polymerization Soft Matter 2013, 9, 2723-2729 10.1039/c2sm27722k
36. Liu, H.; Nakagawa, K.; Chaudhary, D.; Asakuma, Y.; Tadé, M. O. Freeze-Dried Macroporous Foam Prepared from Chitosan/xanthan Gum/montmorillonite Nanocomposites Chem. Eng. Res. Des. 2011, 89, 2356-2364 10.1016/j.cherd.2011.02.023
37. Yokoyama, F.; Achife, E. C.; Momoda, J.; Shimamura, K.; Monobe, K. Morphology of Optically Anisotropic Agarose Hydrogel Prepared by Directional Freezing Colloid Polym. Sci. 1990, 268, 552-558 10.1007/BF01410297
38. Köhnke, T.; Elder, T.; Theliander, H.; Ragauskas, A. J. Ice Templated and Cross-Linked Xylan/nanocrystalline Cellulose Hydrogels Carbohydr. Polym. 2014, 100, 24-30 10.1016/j.carbpol.2013.03.060
39. Wicklein, B.; Kocjan, A.; Salazar-Alvarez, G.; Carosio, F.; Camino, G.; Antonietti, M.; Bergström, L. Thermally Insulating and Fire-Retardant Lightweight Anisotropic Foams Based on Nanocellulose and Graphene Oxide Nat. Nanotechnol. 2015, 10, 277-283 10.1038/nnano.2014.248
40. Darder, M.; Aranda, P.; Ferrer, M. L.; Gutiérrez, M. C.; del Monte, F.; Ruiz-Hitzky, E. Progress in Bionanocomposite and Bioinspired Foams Adv. Mater. 2011, 23, 5262-5267 10.1002/adma.201101617
41. Deville, S. Freeze-Casting of Porous Ceramics: A Review of Current Achievements and Issues Adv. Eng. Mater. 2008, 10, 155-169 10.1002/adem.200700270
42. Gutiérrez, M. C.; Ferrer, M. L.; del Monte, F. Ice-Templated Materials: Sophisticated Structures Exhibiting Enhanced Functionalities Obtained after Unidirectional Freezing and Ice-Segregation-Induced Self-Assembly † Chem. Mater. 2008, 20, 634-648 10.1021/cm702028z
43. Wu, J.; Zhao, Q.; Sun, J.; Zhou, Q. Preparation of Poly(ethylene Glycol) Aligned Porous Cryogels Using a Unidirectional Freezing Technique Soft Matter 2012, 8, 3620-3626 10.1039/c2sm07411g
44. Bai, H.; Polini, A.; Delattre, B.; Tomsia, A. P. Thermoresponsive Composite Hydrogels with Aligned Macroporous Structure by Ice-Templated Assembly Chem. Mater. 2013, 25, 4551-4556 10.1021/cm4025827
45. Wu, J.; Lin, Y.; Sun, J. Anisotropic Volume Change of poly(N-Isopropylacrylamide)-Based Hydrogels with an Aligned Dual-Network Microstructure J. Mater. Chem. 2012, 22, 17449-17451 10.1039/c2jm34010k
46. Wu, X.; Liu, Y.; Li, X.; Wen, P.; Zhang, Y.; Long, Y.; Wang, X.; Guo, Y.; Xing, F.; Gao, J. Preparation of Aligned Porous Gelatin Scaffolds by Unidirectional Freeze-Drying Method Acta Biomater. 2010, 6, 1167-1177 10.1016/j.actbio.2009.08.041
47. Habibi, Y.; Lucia, L. a; Rojas, O. J. Cellulose Nanocrystals: Chemistry, Self-Assembly, and Applications Chem. Rev. 2010, 110, 3479-3500 10.1021/cr900339w
48. Yang, X.; Bakaic, E.; Hoare, T.; Cranston, E. D. Injectable Polysaccharide Hydrogels Reinforced with Cellulose Nanocrystals: Morphology, Rheology, Degradation, and Cytotoxicity Biomacromolecules 2013, 14, 4447-4455 10.1021/bm401364z
49. Yang, J.; Zhao, J.-J.; Xu, F.; Sun, R.-C. Revealing Strong Nanocomposite Hydrogels Reinforced by Cellulose Nanocrystals: Insight into Morphologies and Interactions ACS Appl. Mater. Interfaces 2013, 5, 12960-12967 10.1021/am403669n
50. Zhou, C.; Wu, Q.; Yue, Y.; Zhang, Q. Application of Rod-Shaped Cellulose Nanocrystals in Polyacrylamide Hydrogels J. Colloid Interface Sci. 2011, 353, 116-123 10.1016/j.jcis.2010.09.035
51. Yang, J.; Zhao, J.-J.; Han, C.-R.; Duan, J.-F.; Xu, F.; Sun, R.-C. Tough Nanocomposite Hydrogels from Cellulose Nanocrystals/poly(acrylamide) Clusters: Influence of the Charge Density, Aspect Ratio and Surface Coating with PEG Cellulose 2014, 21, 541-551 10.1007/s10570-013-0111-4
52. Yang, J.; Han, C.-R.; Zhang, X.-M.; Xu, F.; Sun, R.-C. Cellulose Nanocrystals Mechanical Reinforcement in Composite Hydrogels with Multiple Cross-Links: Correlations between Dissipation Properties and Deformation Mechanisms Macromolecules 2014, 47, 4077-4086 10.1021/ma500729q
53. Atifi, S.; Su, S.; Hamad, W. Y. Mechanically Tunable Nanocomposite Hydrogels Based on Functionalized Cellulose Nanocrystals Nord. Pulp Pap. Res. J. 2014, 29, 95-104 10.3183/NPPRJ-2014-29-01-p095-104
54. Hebeish, A.; Farag, S.; Sharaf, S.; Shaheen, T. I. Thermal Responsive Hydrogels Based on Semi Interpenetrating Network of poly(NIPAm) and Cellulose Nanowhiskers Carbohydr. Polym. 2014, 102, 159-166 10.1016/j.carbpol.2013.10.054
55. Yang, J.; Han, C.; Xu, F.; Sun, R. Simple Approach to Reinforce Hydrogels with Cellulose Nanocrystals Nanoscale 2014, 6, 5934-5943 10.1039/c4nr01214c
56. De France, K. J.; Chan, K. J. W.; Cranston, E. D.; Hoare, T. Enhanced Mechanical Properties in Cellulose Nanocrystal-Poly(oligo Ethylene Glycol Methacrylate) Injectable Nanocomposite Hydrogels through Control of Physical and Chemical Cross-Linking Biomacromolecules 2016, 17, 649-660 10.1021/acs.biomac.5b01598
57. Chiang, Y.; Kresge, A. J. Kinetics of Hydrolysis of Acetaldehyde Ethyl Hemiacetal in Aqueous Solution J. Org. Chem. 1985, 50, 5038-5040 10.1021/jo00225a007
58. Smeets, N. M. B.; Bakaic, E.; Patenaude, M.; Hoare, T. Injectable Poly(oligoethylene Glycol Methacrylate)-Based Hydrogels with Tunable Phase Transition Behaviours: Physicochemical and Biological Responses Acta Biomater. 2014, 10, 4143-4155 10.1016/j.actbio.2014.05.035
59. Moon, R. J.; Martini, A.; Nairn, J.; Simonsen, J.; Youngblood, J. Cellulose Nanomaterials Review: Structure, Properties and Nanocomposites Chem. Soc. Rev. 2011, 40, 3941-3994 10.1039/c0cs00108b
60. Eichhorn, S. J. Cellulose Nanowhiskers: Promising Materials for Advanced Applications Soft Matter 2011, 7, 303-315 10.1039/C0SM00142B
61. Azizi Samir, M. A. S.; Alloin, F.; Dufresne, A. Review of Recent Research into Cellulosic Whiskers, Their Properties and Their Application in Nanocomposite Field Biomacromolecules 2005, 6, 612-626 10.1021/bm0493685
62. Lutz, J.-F. Polymerization of Oligo(ethylene Glycol) (meth)acrylates: Toward New Generations of Smart Biocompatible Materials J. Polym. Sci., Part A: Polym. Chem. 2008, 46, 3459-3470 10.1002/pola.22706
63. Smeets, N. M. B.; Bakaic, E.; Patenaude, M.; Hoare, T. Injectable and Tunable Poly(ethylene Glycol) Analogue Hydrogels Based on Poly(oligoethylene Glycol Methacrylate) Chem. Commun. 2014, 50, 3306-3309 10.1039/c3cc48514e
64. Beck-candanedo, S.; Roman, M.; Gray, D. G. Effect of Reaction Conditions on the Properties and Behavior of Wood Cellulose Nanocrystal Suspensions Biomacromolecules 2005, 6, 1048-1054 10.1021/bm049300p
65. Beck, S.; Méthot, M.; Bouchard, J. General Procedure for Determining Cellulose Nanocrystal Sulfate Half-Ester Content by Conductometric Titration Cellulose 2015, 22, 101-116 10.1007/s10570-014-0513-y
66. Sun, B.; Hou, Q.; Liu, Z.; Ni, Y. Sodium Periodate Oxidation of Cellulose Nanocrystal and Its Application as a Paper Wet Strength Additive Cellulose 2015, 22, 1135-1146 10.1007/s10570-015-0575-5
67. Brunauer, S.; Emmett, P. H.; Teller, E. Adsorption of Gases in Multimolecular Layers J. Am. Chem. Soc. 1938, 60, 309-319 10.1021/ja01269a023
68. Förster, S.; Fischer, S.; Zielske, K.; Schellbach, C.; Sztucki, M.; Lindner, P.; Perlich, J. Calculation of Scattering-Patterns of Ordered Nano- and Mesoscale Materials Adv. Colloid Interface Sci. 2011, 163, 53-83 10.1016/j.cis.2010.12.003
69. Kumar, A.; Negi, Y. S.; Choudhary, V.; Bhardwaj, N. K. Characterization of Cellulose Nanocrystals Produced by Acid-Hydrolysis from Sugarcane Bagasse as Agro-Waste J. Mater. Phys. Chem. 2014, 2, 1-8
70. Heath, L.; Thielemans, W. Cellulose Nanowhisker Aerogels Green Chem. 2010, 12, 1448-1453 10.1039/c0gc00035c
71. Seeck, O. H.; Murphy, B. X-Ray Diffraction: Modern Experimental Techniques; Pan Stanford Publishing: Singapore, 2015.
72. Han, J.; Zhou, C.; Wu, Y.; Liu, F.; Wu, Q. Self-Assembling Behavior of Cellulose Nanoparticles during Freeze-Drying: Effect of Suspension Concentration, Particle Size, Crystal Structure, and Surface Charge Biomacromolecules 2013, 14, 1529-1540 10.1021/bm4001734
73. Tibbitt, M. W.; Rodell, C. B.; Burdick, J. A.; Anseth, K. S. Progress in Material Design for Biomedical Applications Proc. Natl. Acad. Sci. U. S. A. 2015, 112, 14444-14451 10.1073/pnas.1516247112
74. Deville, S.; Saiz, E.; Tomsia, A. P. Ice-Templated Porous Alumina Structures Acta Mater. 2007, 55, 1965-1974 10.1016/j.actamat.2006.11.003