Light-induced depigmentation in planarians models the pathophysiology of acute porphyrias

eLife

Volumn 5, Issue MAY2016, 2016, Pages

  Stubenhaus, Bradford M ^a   Dustin, John P ^a   Neverett, Emily R ^a   Beaudry, Megan S ^a   Nadeau, Leanna E ^a   Burk McCoy, Ethan ^a   He, Xinwen ^b,c   Pearson, Bret J ^b,c,d   Pellettieri, Jason ^a  

^a KEENE STATE COLLEGE   (United States)

^b HOSPITAL FOR SICK CHILDREN   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INDOLEAMINE 2,3 DIOXYGENASE; OMMOCHROME; PIGMENT; PORPHYRIN; TRYPTOPHAN 2,3 DIOXYGENASE; UNCLASSIFIED DRUG; HELMINTH PROTEIN; HEME; PHENOTHIAZINE DERIVATIVE;

ARTICLE; BIOSYNTHESIS; CELL LOSS; CONTROLLED STUDY; DEPIGMENTATION; FLUORESCENCE IN SITU HYBRIDIZATION; IMAGE PROCESSING; LIGHT EXPOSURE; MOLECULAR CLONING; MOLECULAR PATHOLOGY; NONHUMAN; PHENOTYPE; PHOTOSENSITIVITY; PIGMENT CELL; PORPHYRIA; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; SCHMIDTEA MEDITERRANEA; STARVATION; TUNEL ASSAY; TURBELLARIA; ACUTE INTERMITTENT PORPHYRIA; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LIGHT; METABOLISM; PATHOPHYSIOLOGY; RADIATION RESPONSE; SKIN PIGMENTATION;

ANIMALS; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HELMINTH PROTEINS; HEME; HUMANS; LIGHT; PHENOTHIAZINES; PIGMENTS, BIOLOGICAL; PLANARIANS; PORPHYRIA, ACUTE INTERMITTENT; PORPHYRINS; SKIN PIGMENTATION; STARVATION;

EID: 84971657294     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.14175     Document Type: Article

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