B7-H4(B7x)-mediated cross-talk between glioma-initiating cells and macrophages via the IL6/JAK/STAT3 pathway lead to poor prognosis in glioma patients

Clinical Cancer Research

Volumn 22, Issue 11, 2016, Pages 2778-2790

  Yao, Yu ^a   Ye, Hongxing ^b   Qi, Zengxin ^c   Mo, Lianjie ^d   Yue, Qi ^c   Baral, Aparajita ^e   Hoon, Dave S B ^f   Vera, Juan Carlos ^g   Heiss, John D ^g   Chen, Clark C ^h   Hua, Wei ^a   Zhang, Jianmin ^b   Jin, Kunlin ⁱ   Wang, Yin ⁱ   Mao, Ying ^j   Zang, Xingxing ^c   Zhou, Liangfu ^a  

^a FUDAN UNIVERSITY   (China)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c FUDAN UNIVERSITY   (China)

^d ZHEJIANG UNIVERSITY   (China)

^e ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^f JOHN WAYNE CANCER INSTITUTE   (United States)

^g NATIONAL INSTITUTES OF HEALTH   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ UNIVERSITY OF NORTH TEXAS HEALTH SCIENCE CENTER   (United States)

^j ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

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Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CXCL9 CHEMOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 6; INTERLEUKIN 8; JANUS KINASE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; NEUTRALIZING ANTIBODY; RANTES; SHORT HAIRPIN RNA; STAT3 PROTEIN; V SET DOMAIN CONTAINING T CELL ACTIVATION INHIBITOR 1; IL6 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN; VTCN1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOREGULATION; B7 H4 GENE; CANCER GRADING; CANCER PROGNOSIS; CANCER SURVIVAL; CELL INTERACTION; CELL PHAGOCYTOSIS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ASSOCIATION; GENE; GENE SILENCING; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREGULATION; IN VITRO STUDY; IN VIVO STUDY; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MAJOR CLINICAL STUDY; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; TISSUE LEVEL; TUMOR MICROENVIRONMENT; TUMOR REGRESSION; TUMOR XENOGRAFT; ADOLESCENT; ADULT; AGED; ANIMAL; ANTIBODY SPECIFICITY; BRAIN TUMOR; C57BL MOUSE; CANCER STEM CELL; CANCER TRANSPLANTATION; FEMALE; GLIOBLASTOMA; IMMUNOLOGY; KAPLAN MEIER METHOD; LYMPHOCYTE ACTIVATION; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PHYSIOLOGY; PROGNOSIS; RETROSPECTIVE STUDY; TUMOR CELL LINE; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ANIMALS; BRAIN NEOPLASMS; CELL LINE, TUMOR; FEMALE; GLIOBLASTOMA; HUMANS; INTERLEUKIN-6; JANUS KINASES; KAPLAN-MEIER ESTIMATE; LYMPHOCYTE ACTIVATION; MACROPHAGES; MALE; MICE, INBRED C57BL; MIDDLE AGED; NEOPLASM TRANSPLANTATION; NEOPLASTIC STEM CELLS; ORGAN SPECIFICITY; PROGNOSIS; RETROSPECTIVE STUDIES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; V-SET DOMAIN-CONTAINING T-CELL ACTIVATION INHIBITOR 1; YOUNG ADULT;

EID: 84971520451     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-15-0858     Document Type: Article

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