Transfer of malignant trait to BRCA1 deficient human fibroblasts following exposure to serum of cancer patients

Journal of Experimental and Clinical Cancer Research

Volumn 35, Issue 1, 2016, Pages

  Hamam, Dana ^a,b   Abdouh, Mohamed ^a   Gao, Zu Hua ^a   Arena, Vincenzo ^c   Arena, Manuel ^d   Arena, Goffredo Orazio ^a,e  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c Santo Bambino Hospital   (Italy)

^d UNIVERSITY OF CATANIA   (Italy)

^e MCGILL UNIVERSITY   (Canada)

Author keywords

BRCA1; Exosomes; Fibroblasts; Genometastasis; Metastasis; Transformation; Tumor suppressor genes

Indexed keywords

BRCA1 PROTEIN; CRISPR ASSOCIATED PROTEIN; BRCA1 PROTEIN, HUMAN; CONDITIONED MEDIUM;

ADULT; AGED; ANUS CARCINOMA; ARTICLE; BLOOD DONOR; BREAST CANCER; CANCER CELL; CANCER PATIENT; CELL MIGRATION; CELL PROLIFERATION; CLINICAL ARTICLE; COLORECTAL CANCER; CONTROLLED STUDY; EMBRYO CELL; EXOSOME; FEMALE; FIBROBLAST; HUMAN; HUMAN CELL; LIVER METASTASIS; LUNG METASTASIS; MALE; MALIGNANT TRANSFORMATION; NEUROENDOCRINE TUMOR; PANCREAS CANCER; PHENOTYPE; PRIORITY JOURNAL; SQUAMOUS CELL CARCINOMA; WILD TYPE; ANIMAL; BLOOD; CANCER TRANSPLANTATION; CELL TRANSFORMATION; CHEMISTRY; CONDITIONED MEDIUM; CYTOLOGY; DRUG EFFECTS; GENE INACTIVATION; GENETICS; HEK293 CELL LINE; MIDDLE AGED; MOUSE; NEOPLASM; PATHOLOGY; PHARMACOLOGY; SERUM;

ADULT; AGED; ANIMALS; BRCA1 PROTEIN; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; CULTURE MEDIA, CONDITIONED; FIBROBLASTS; GENE KNOCKOUT TECHNIQUES; HEK293 CELLS; HUMANS; MICE; MIDDLE AGED; NEOPLASM TRANSPLANTATION; NEOPLASMS; SERUM;

EID: 84971499081     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/s13046-016-0360-9     Document Type: Article

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