-
1
-
-
34247194211
-
Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025
-
Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A. Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res. 2007; 22(3):465–75.
-
(2007)
J Bone Miner Res
, vol.22
, Issue.3
, pp. 465-475
-
-
Burge, R.1
Dawson-Hughes, B.2
Solomon, D.H.3
Wong, J.B.4
King, A.5
Tosteson, A.6
-
2
-
-
33750209491
-
An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
-
Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int. 2006; 17(12):1726–33.
-
(2006)
Osteoporos Int
, vol.17
, Issue.12
, pp. 1726-1733
-
-
Johnell, O.1
Kanis, J.A.2
-
3
-
-
84966785101
-
-
Office of the Surgeon General (US). Rockville, MD Office of the Surgeon General;
-
Office of the Surgeon General (US). Bone health and osteoporosis: a report of the Surgeon General. Rockville, MD: Office of the Surgeon General; 2004.
-
(2004)
Bone health and osteoporosis a report of the Surgeon General
-
-
-
4
-
-
33646889773
-
Bone quality—the material and structural basis of bone strength and fragility
-
Seeman E, Delmas PD. Bone quality—the material and structural basis of bone strength and fragility. N Engl J Med. 2006; 354(21):2250–61.
-
(2006)
N Engl J Med
, vol.354
, Issue.21
, pp. 2250-2261
-
-
Seeman, E.1
Delmas, P.D.2
-
5
-
-
0025644610
-
Femoral cortical/cancellous bone related to age
-
Høiseth A, Alho A, Husby T. Femoral cortical/cancellous bone related to age. Acta Radiol. 1990; 31(6):626–7.
-
(1990)
Acta Radiol
, vol.31
, Issue.6
, pp. 626-627
-
-
Høiseth, A.1
Alho, A.2
Husby, T.3
-
6
-
-
0019505458
-
Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis
-
Riggs BL, Wahner HW, Dunn WL, Mazess RB, Offord KP, Melton LJ 3rd. Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest. 1981; 67(2):328–35.
-
(1981)
J Clin Invest
, vol.67
, Issue.2
, pp. 328-335
-
-
Riggs, B.L.1
Wahner, H.W.2
Dunn, W.L.3
Mazess, R.B.4
Offord, K.P.5
Melton, L.J.6
-
7
-
-
77952111123
-
Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study
-
Zebaze RM, Ghasem-Zadeh A, Bohte A, et al. Intracortical remodelling and porosity in the distal radius and post-mortem femurs of women: a cross-sectional study. Lancet. 2010; 375(9727):1729–36.
-
(2010)
Lancet
, vol.375
, Issue.9727
, pp. 1729-1736
-
-
Zebaze, R.M.1
Ghasem-Zadeh, A.2
Bohte, A.3
-
8
-
-
0023901292
-
Stiffness of compact bone: effects of porosity and density
-
Schaffler MB, Burr DB. Stiffness of compact bone: effects of porosity and density. J Biomech. 1988; 21(1):13–6.
-
(1988)
J Biomech
, vol.21
, Issue.1
, pp. 13-16
-
-
Schaffler, M.B.1
Burr, D.B.2
-
9
-
-
45749112558
-
Structural basis of growth-related gain and age-related loss of bone strength
-
Seeman E. Structural basis of growth-related gain and age-related loss of bone strength. Rheumatology (Oxford). 2008; 47 Suppl 4:iv2–8.
-
(2008)
Rheumatology (Oxford)
, vol.47
, pp. 2-8
-
-
Seeman, E.1
-
10
-
-
69049083492
-
Denosumab for prevention of fractures in postmenopausal women with osteoporosis
-
Cummings SR, San Martin J, McClung MR, et al. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med. 2009; 361(8):756–65.
-
(2009)
N Engl J Med
, vol.361
, Issue.8
, pp. 756-765
-
-
Cummings, S.R.1
San Martin, J.2
McClung, M.R.3
-
11
-
-
58649113384
-
Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL
-
Kostenuik PJ, Nguyen HQ, McCabe J, et al. Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock-in mice that express chimeric (murine/human) RANKL. J Bone Miner Res. 2009; 24(2):182–95.
-
(2009)
J Bone Miner Res
, vol.24
, Issue.2
, pp. 182-195
-
-
Kostenuik, P.J.1
Nguyen, H.Q.2
McCabe, J.3
-
12
-
-
84860364397
-
Bench to bedside: elucidation of the OPG-RANK-RANKL pathway and the development of denosumab
-
Lacey DL, Boyle WJ, Simonet WS, et al. Bench to bedside: elucidation of the OPG-RANK-RANKL pathway and the development of denosumab. Nat Rev Drug Discov. 2012; 11(5):401–19.
-
(2012)
Nat Rev Drug Discov
, vol.11
, Issue.5
, pp. 401-419
-
-
Lacey, D.L.1
Boyle, W.J.2
Simonet, W.S.3
-
13
-
-
79958772395
-
Decreased bone remodeling and porosity are associated with improved bone strength in ovariectomized cynomolgus monkeys treated with denosumab, a fully human RANKL antibody
-
Kostenuik PJ, Smith SY, Jolette J, Schroeder J, Pyrah I, Ominsky MS. Decreased bone remodeling and porosity are associated with improved bone strength in ovariectomized cynomolgus monkeys treated with denosumab, a fully human RANKL antibody. Bone. 2011; 49(2):151–61.
-
(2011)
Bone
, vol.49
, Issue.2
, pp. 151-161
-
-
Kostenuik, P.J.1
Smith, S.Y.2
Jolette, J.3
Schroeder, J.4
Pyrah, I.5
Ominsky, M.S.6
-
14
-
-
84890155336
-
Differing effects of denosumab and alendronate on cortical and trabecular bone
-
Zebaze RM, Libanati C, Austin M, et al. Differing effects of denosumab and alendronate on cortical and trabecular bone. Bone. 2014; 59:173–9.
-
(2014)
Bone
, vol.59
, pp. 173-179
-
-
Zebaze, R.M.1
Libanati, C.2
Austin, M.3
-
15
-
-
84882712081
-
Improvements in hip trabecular, subcortical, and cortical density and mass in postmenopausal women with osteoporosis treated with denosumab
-
Genant HK, Libanati C, Engelke K, et al. Improvements in hip trabecular, subcortical, and cortical density and mass in postmenopausal women with osteoporosis treated with denosumab. Bone. 2013; 56(2):482–8.
-
(2013)
Bone
, vol.56
, Issue.2
, pp. 482-488
-
-
Genant, H.K.1
Libanati, C.2
Engelke, K.3
-
16
-
-
52949090528
-
Femoral bone strength and its relation to cortical and trabecular changes after treatment with PTH, alendronate, and their combination as assessed by finite element analysis of quantitative CT scans
-
Keaveny TM, Hoffmann PF, Singh M, et al. Femoral bone strength and its relation to cortical and trabecular changes after treatment with PTH, alendronate, and their combination as assessed by finite element analysis of quantitative CT scans. J Bone Miner Res. 2008; 23(12):1974–82.
-
(2008)
J Bone Miner Res
, vol.23
, Issue.12
, pp. 1974-1982
-
-
Keaveny, T.M.1
Hoffmann, P.F.2
Singh, M.3
-
17
-
-
77953522832
-
Age-dependence of femoral strength in white women and men
-
Keaveny TM, Kopperdahl DL, Melton LJ 3rd, et al. Age-dependence of femoral strength in white women and men. J Bone Miner Res. 2010; 25(5):994–1001.
-
(2010)
J Bone Miner Res
, vol.25
, Issue.5
, pp. 994-1001
-
-
Keaveny, T.M.1
Kopperdahl, D.L.2
Melton, L.J.3
-
18
-
-
84919881052
-
Denosumab rapidly increases cortical bone in key locations of the femur: a 3D bone mapping study in women with osteoporosis
-
Poole KE, Treece GM, Gee AH, et al. Denosumab rapidly increases cortical bone in key locations of the femur: a 3D bone mapping study in women with osteoporosis. J Bone Miner Res. 2015; 30(1):46–54.
-
(2015)
J Bone Miner Res
, vol.30
, Issue.1
, pp. 46-54
-
-
Poole, K.E.1
Treece, G.M.2
Gee, A.H.3
-
20
-
-
84877072861
-
Denosumab densitometric changes assessed by quantitative computed tomography at the spine and hip in postmenopausal women with osteoporosis
-
McClung MR, Zanchetta JR, Høiseth A, et al. Denosumab densitometric changes assessed by quantitative computed tomography at the spine and hip in postmenopausal women with osteoporosis. J Clin Densitom. 2013; 16(2):250–6.
-
(2013)
J Clin Densitom
, vol.16
, Issue.2
, pp. 250-256
-
-
McClung, M.R.1
Zanchetta, J.R.2
Høiseth, A.3
-
21
-
-
84873495411
-
A new method of segmentation of compact-appearing, transitional and trabecular compartments and quantification of cortical porosity from high resolution peripheral quantitative computed tomographic images
-
Zebaze R, Ghasem-Zadeh A, Mbala A, Seeman E. A new method of segmentation of compact-appearing, transitional and trabecular compartments and quantification of cortical porosity from high resolution peripheral quantitative computed tomographic images. Bone. 2013; 54(1):8–20.
-
(2013)
Bone
, vol.54
, Issue.1
, pp. 8-20
-
-
Zebaze, R.1
Ghasem-Zadeh, A.2
Mbala, A.3
Seeman, E.4
-
22
-
-
84939000199
-
Measurement of cortical porosity of the proximal femur improves identification of women with nonvertebral fragility fractures
-
Ahmed LA, Shigdel R, Joakimsen RM, et al. Measurement of cortical porosity of the proximal femur improves identification of women with nonvertebral fragility fractures. Osteoporos Int. 2015; 26(8):2137–46.
-
(2015)
Osteoporos Int
, vol.26
, Issue.8
, pp. 2137-2146
-
-
Ahmed, L.A.1
Shigdel, R.2
Joakimsen, R.M.3
-
23
-
-
84934273877
-
Bone turnover markers are associated with higher cortical porosity, thinner cortices, and larger size of the proximal femur and non-vertebral fractures
-
Shigdel R, Osima M, Ahmed LA, et al. Bone turnover markers are associated with higher cortical porosity, thinner cortices, and larger size of the proximal femur and non-vertebral fractures. Bone. 2015; 81:1–6.
-
(2015)
Bone
, vol.81
, pp. 1-6
-
-
Shigdel, R.1
Osima, M.2
Ahmed, L.A.3
-
24
-
-
84890956226
-
Femoral and vertebral strength improvements in postmenopausal women with osteoporosis treated with denosumab
-
Keaveny TM, McClung MR, Genant HK, et al. Femoral and vertebral strength improvements in postmenopausal women with osteoporosis treated with denosumab. J Bone Miner Res. 2014; 29(1):158–65.
-
(2014)
J Bone Miner Res
, vol.29
, Issue.1
, pp. 158-165
-
-
Keaveny, T.M.1
McClung, M.R.2
Genant, H.K.3
-
25
-
-
84883737764
-
Anti-resorptive agents reduce the size of resorption cavities: a three-dimensional dynamic bone histomorphometry study
-
Matheny JB, Slyfield CR, Tkachenko EV, et al. Anti-resorptive agents reduce the size of resorption cavities: a three-dimensional dynamic bone histomorphometry study. Bone. 2013; 57(1):277–83.
-
(2013)
Bone
, vol.57
, Issue.1
, pp. 277-283
-
-
Matheny, J.B.1
Slyfield, C.R.2
Tkachenko, E.V.3
-
26
-
-
0000348680
-
Suggested sequential mode of control of changes in cell behaviour in adult bone remodelling
-
Hattner R, Epker BN, Frost HM. Suggested sequential mode of control of changes in cell behaviour in adult bone remodelling. Nature. 1965; 206(983):489–90.
-
(1965)
Nature
, vol.206
, Issue.983
, pp. 489-490
-
-
Hattner, R.1
Epker, B.N.2
Frost, H.M.3
-
27
-
-
0002313309
-
-
In, Marcus R, Feldman D, Kelsey J, editors. Osteoporosis. San Diego, CA Academic Press;, p
-
Parfitt AM. Skeletal heterogeneity and the purposes of bone remodelling: implications for the understanding of osteoporosis. In: Marcus R, Feldman D, Kelsey J, editors. Osteoporosis. San Diego, CA: Academic Press; 1996. p. 315–39.
-
(1996)
Skeletal heterogeneity and the purposes of bone remodelling implications for the understanding of osteoporosis
, pp. 315--339
-
-
Parfitt, A.M.1
-
30
-
-
0142027593
-
Aging of microstructural compartments in human compact bone
-
Akkus O, Polyakova-Akkus A, Adar F, Schaffler MB. Aging of microstructural compartments in human compact bone. J Bone Miner Res. 2003; 18(6):1012–9.
-
(2003)
J Bone Miner Res
, vol.18
, Issue.6
, pp. 1012-1019
-
-
Akkus, O.1
Polyakova-Akkus, A.2
Adar, F.3
Schaffler, M.B.4
-
31
-
-
79958772773
-
Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys
-
Ominsky MS, Stouch B, Schroeder J, et al. Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys. Bone. 2011; 49(2):162–73.
-
(2011)
Bone
, vol.49
, Issue.2
, pp. 162-173
-
-
Ominsky, M.S.1
Stouch, B.2
Schroeder, J.3
-
32
-
-
78649556809
-
A longitudinal HR-pQCT study of alendronate treatment in postmenopausal women with low bone density: relations among density, cortical and trabecular microarchitecture, biomechanics, and bone turnover
-
Burghardt AJ, Kazakia GJ, Sode M, de Papp AE, Link TM, Majumdar S. A longitudinal HR-pQCT study of alendronate treatment in postmenopausal women with low bone density: relations among density, cortical and trabecular microarchitecture, biomechanics, and bone turnover. J Bone Miner Res. 2010; 25(12):2558–71.
-
(2010)
J Bone Miner Res
, vol.25
, Issue.12
, pp. 2558-2571
-
-
Burghardt, A.J.1
Kazakia, G.J.2
Sode, M.3
de Papp, A.E.4
Link, T.M.5
Majumdar, S.6
-
33
-
-
34147181146
-
The bone mineralization density distribution as a fingerprint of the mineralization process
-
Ruffoni D, Fratzl P, Roschger P, Klaushofer K, Weinkamer R. The bone mineralization density distribution as a fingerprint of the mineralization process. Bone. 2007; 40(5):1308–19.
-
(2007)
Bone
, vol.40
, Issue.5
, pp. 1308-1319
-
-
Ruffoni, D.1
Fratzl, P.2
Roschger, P.3
Klaushofer, K.4
Weinkamer, R.5
|