The Effect of Diabetes Medication on Cognitive Function: Evidence from the PATH Through Life Study

BioMed Research International

Volumn 2016, Issue , 2016, Pages

  Herath, Pushpani M ^a   Cherbuin, Nicolas ^a   Eramudugolla, Ranmalee ^a   Anstey, Kaarin J ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; METFORMIN; ORAL ANTIDIABETIC AGENT; ANTIDIABETIC AGENT;

AGED; ARTICLE; AUSTRALIA; COGNITION; COGNITIVE DEFECT; COHORT ANALYSIS; CONTROLLED STUDY; DIABETES MELLITUS; DIET THERAPY; EXECUTIVE FUNCTION; FEMALE; HUMAN; INSULIN TREATMENT; LEARNING; MAJOR CLINICAL STUDY; MALE; NEUROPSYCHOLOGICAL TEST; WORKING MEMORY; ADULT; DRUG EFFECTS; MIDDLE AGED; PATHOPHYSIOLOGY; YOUNG ADULT;

ADULT; AGED; COGNITION; COHORT STUDIES; DIABETES MELLITUS; FEMALE; HUMANS; HYPOGLYCEMIC AGENTS; MALE; METFORMIN; MIDDLE AGED; YOUNG ADULT;

EID: 84971382130     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2016/7208429     Document Type: Article

References (28)

1. S. Craft and G. S. Watson, "Insulin and neurodegenerative disease: shared and specificmechanisms, "TheLancetNeurology, vol. 3, no. 3, pp. 169-178, 2004.
2. M. W. J. Strachan, R. M. Reynolds, R. E. Marioni, and J. F. Price, "Cognitive function, dementia and type 2 diabetes mellitus in the elderly, " Nature Reviews Endocrinology, vol. 7, no. 2, pp. 108-114, 2011.
3. W. A. Banks, J. B. Owen, and M. A. Erickson, "Insulin in the brain: there and back again, " Pharmacology and Therapeutics, vol. 136, no. 1, pp. 82-93, 2012.
4. C. T. Kodl and E. R. Seaquist, "Cognitive dysfunction and diabetes mellitus, " Endocrine Reviews, vol. 29, no. 4, pp. 494-511, 2008.
5. M. A. Testa andD. C. Simonson, "Health economic benefits and quality of life during improved glycemic control in patientswith type 2 diabetesmellitus: a randomized, controlled, double-blind trial, " The Journal of the AmericanMedical Association, vol. 280, no. 17, pp. 1490-1496, 1998.
6. T. J. Gradman, A. Laws, L. W. Thompson, and G. M. Reaven, "Verbal learning and/or memory improves with glycemic control in older subjects with non-insulin-dependent diabetes mellitus, " Journal of the American Geriatrics Society, vol. 41, no. 12, pp. 1305-1312, 1993.
7. G. S. Meneilly, E. Cheung, D. Tessier, C. Yakura, andH. Tuokko, "The effect of improved glycemic control on cognitive functions in the elderly patientwith diabetes, " Journals of Gerontology, vol. 48, no. 4, pp. M117-M121, 1993.
8. L. He, A. Sabet, S. Djedjos et al., "Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein, " Cell, vol. 137, no. 4, pp. 635-646, 2009.
9. K. abuzek, D. Suchy, B. Gabryel, A. Bielecka, S. Liber, and B. Okopién, "Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide, " Pharmacological Reports, vol. 62, no. 5, pp. 956-965, 2010.
10. D. Kirpichnikov, S. I. McFarlane, and J. R. Sowers, "Metformin: an update, " Annals of Internal Medicine, vol. 137, no. 1, pp. 25-33, 2002.
11. S. Craft, L. D. Baker, T. J. Montine et al., "Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial, " Archives of Neurology, vol. 69, no. 1, pp. 29-38, 2012.
12. V. Ott, C. Benedict, B. Schultes, J. Born, and M. Hallschmid, "Intranasal administration of insulin to the brain impacts cognitive function and peripheral metabolism, " Diabetes, Obesity and Metabolism, vol. 14, no. 3, pp. 214-221, 2012.
13. K. J. Anstey, H. Christensen, P. Butterworth et al., "Cohort profile: the PATH through life project, " International Journal of Epidemiology, vol. 41, no. 4, Article IDdyr025, pp. 951-960, 2012.
14. M. Stafford, H. Hemingway, S. A. Stansfeld, E. Brunner, and M. Marmot, "Behavioural and biological correlates of physical functioning in middle aged office workers: the UKWhitehall II study, " Journal of Epidemiology and Community Health, vol. 52, no. 6, pp. 353-358, 1998.
15. D. C. Delis, J. H. Kramer, E. Kaplan, and B. A. Ober, California Verbal Learning Test, Psychological Corporation/Harcourt Brace Jovanovich, SanAntonio, Tex, USA, 1987.
16. D. Wechsler, "A standardized memory scale for clinical use, "The Journal of Psychology, vol. 19, no. 1, pp. 87-95, 1945.
17. A. Baddeley, H. Emslie, and I. Nimmo-Smith, The Spot-the-Word Test, ThamesValley TestCompany, Bury St Edmunds, UK, 1992.
18. A. Smith, Symbol Digit Modalities Test (SDMT) Manual, Western Psychological Services, Los Angeles, Calif, USA, 1982.
19. K. J. Anstey, K. Dear, H. Christensen, and A. F. Jorm, "Biomarkers, health, lifestyle, and demographic variables as correlates of reaction time performance in early, middle, and late adulthood, " Quarterly Journal of Experimental Psychology Section A:Human Experimental Psychology, vol. 58, no. 1, pp. 5-21, 2005.
20. R. M. Reitan, "Validity of the Trail Making Test as an indicator of organic brain damage, " Perceptual andMotor Skills, vol. 8, no. 3, pp. 271-276, 1958.
21. J. Tiffin and E. J. Asher, Perdue Pegboard Test; ExaminerManual, Science Research Associates, Chicago, Ill, USA, 1968.
22. F. Grodstein, J. Chen, R. S. Wilson, and J. E. Manson, "Type 2 diabetes and cognitive function in community-dwelling elderly women, " Diabetes Care, vol. 24, no. 6, pp. 1060-1065, 2001.
23. G. Logroscino, J. H. Kang, and F. Grodstein, "Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years, " British Medical Journal, vol. 328, no. 7439, article 548, 2004.
24. K. Samaras, H. L. Lutgers, N. A. Kochan et al., "The impact of glucose disorders on cognition and brain volumes in the elderly: the Sydney Memory and Ageing Study, " Age, vol. 36, no. 2, pp. 977-993, 2014.
25. P. K. Elias, M. F. Elias, R. B. D'Agostino et al., "NIDDM and blood pressure as risk factors for poor cognitive performance: the Framingham Study, " Diabetes Care, vol. 20, no. 9, pp. 1388-1395, 1997.
26. M. A. Espeland, M. E. Miller, J. S. Goveas et al., "Cognitive function and fine motor speed in older women with diabetes mellitus: results from the women's health initiative study of cognitive aging, " Journal of Women's Health, vol. 20, no. 10, pp. 1435-1443, 2011.
27. E. M. Moore, A. G. Mander, D. Ames et al., "Increased risk of cognitive impairment in patients with diabetes is associated with metformin, " Diabetes Care, vol. 36, no. 10, pp. 2981-2987, 2013.
28. T. P. Ng, L. Feng, K. B. Yap, T. S. Lee, C. H. Tan, and B. Winblad, "Long-term metformin usage and cognitive function among older adults with diabetes, " Journal of Alzheimer's Disease, vol. 41, no. 1, pp. 61-68, 2014.