메뉴 건너뛰기




Volumn 69, Issue 5, 2017, Pages 525-528

Deferasirox pharmacokinetic evaluation in β-thalassaemia paediatric patients

Author keywords

AUC; iron chelator; iron overload; transfusion; thalassaemia

Indexed keywords

DEFERASIROX; BENZOIC ACID DERIVATIVE; IRON; IRON CHELATING AGENT; TRIAZOLE DERIVATIVE;

EID: 84971323673     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12559     Document Type: Article
Times cited : (7)

References (18)
  • 1
    • 38349157810 scopus 로고    scopus 로고
    • Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major
    • Cohen AR et al. Effect of transfusional iron intake on response to chelation therapy in beta-thalassemia major. Blood 2008; 111: 583–587.
    • (2008) Blood , vol.111 , pp. 583-587
    • Cohen, A.R.1
  • 3
    • 77950945189 scopus 로고    scopus 로고
    • Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state
    • Waldmeier F et al. Pharmacokinetics, metabolism, and disposition of deferasirox in beta-thalassemic patients with transfusion-dependent iron overload who are at pharmacokinetic steady state. Drug Metab Dispos 2010; 38: 808–816.
    • (2010) Drug Metab Dispos , vol.38 , pp. 808-816
    • Waldmeier, F.1
  • 4
    • 57349185625 scopus 로고    scopus 로고
    • Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats
    • Bruin GJ et al. Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats. Drug Metab Dispos 2008; 36: 2523–2538.
    • (2008) Drug Metab Dispos , vol.36 , pp. 2523-2538
    • Bruin, G.J.1
  • 6
    • 49249111541 scopus 로고    scopus 로고
    • Once-daily oral deferasirox for the treatment of transfusional iron overload
    • Galanello R, Origa R. Once-daily oral deferasirox for the treatment of transfusional iron overload. Expert Rev Clin Pharmacol 2008; 1: 231–240.
    • (2008) Expert Rev Clin Pharmacol , vol.1 , pp. 231-240
    • Galanello, R.1    Origa, R.2
  • 7
    • 0037906104 scopus 로고    scopus 로고
    • Safety, tolerability, and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron overload due to beta-thalassemia
    • Galanello R et al. Safety, tolerability, and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron overload due to beta-thalassemia. J Clin Pharmacol 2003; 43: 565–572.
    • (2003) J Clin Pharmacol , vol.43 , pp. 565-572
    • Galanello, R.1
  • 8
    • 77950425913 scopus 로고    scopus 로고
    • Deferasirox pharmacokinetics in patients with adequate versus inadequate response
    • Chirnomas D et al. Deferasirox pharmacokinetics in patients with adequate versus inadequate response. Blood 2009; 114: 4009–4013.
    • (2009) Blood , vol.114 , pp. 4009-4013
    • Chirnomas, D.1
  • 9
    • 79961008228 scopus 로고    scopus 로고
    • Iron chelation with deferasirox in adult and pediatric patients with thalassemia major: efficacy and safety during 5 years' follow-up
    • Cappellini MD et al. Iron chelation with deferasirox in adult and pediatric patients with thalassemia major: efficacy and safety during 5 years' follow-up. Blood 2011; 118: 884–893.
    • (2011) Blood , vol.118 , pp. 884-893
    • Cappellini, M.D.1
  • 10
    • 84555187557 scopus 로고    scopus 로고
    • A case of hypophosphatemic osteomalacia secondary to deferasirox therapy
    • Milat F et al. A case of hypophosphatemic osteomalacia secondary to deferasirox therapy. J Bone Miner Res 2012; 27: 219–222.
    • (2012) J Bone Miner Res , vol.27 , pp. 219-222
    • Milat, F.1
  • 11
    • 33646414765 scopus 로고    scopus 로고
    • A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia
    • Cappellini MD et al. A phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with beta-thalassemia. Blood 2006; 107: 3455–3462.
    • (2006) Blood , vol.107 , pp. 3455-3462
    • Cappellini, M.D.1
  • 12
    • 84929959628 scopus 로고    scopus 로고
    • Influence of single-nucleotide polymorphisms on deferasirox C trough levels and effectiveness
    • Cusato J et al. Influence of single-nucleotide polymorphisms on deferasirox C trough levels and effectiveness. Pharmacogenomics J 2014; 15: 263–271.
    • (2014) Pharmacogenomics J , vol.15 , pp. 263-271
    • Cusato, J.1
  • 13
    • 84859444371 scopus 로고    scopus 로고
    • A new HPLC UV validated method for therapeutic monitoring of deferasirox in thalassaemic patients
    • De Francia S et al. A new HPLC UV validated method for therapeutic monitoring of deferasirox in thalassaemic patients. J Chromatogr B Analyt Technol Biomed Life Sci 2012; 893–894: 127–133.
    • (2012) J Chromatogr B Analyt Technol Biomed Life Sci , vol.893-894 , pp. 127-133
    • De Francia, S.1
  • 14
    • 33749991316 scopus 로고    scopus 로고
    • Phase II clinical evaluation of deferasirox, a once-daily oral chelating agent, in pediatric patients with beta-thalassemia major
    • Galanello R et al. Phase II clinical evaluation of deferasirox, a once-daily oral chelating agent, in pediatric patients with beta-thalassemia major. Haematologica 2006; 91: 1343–1351.
    • (2006) Haematologica , vol.91 , pp. 1343-1351
    • Galanello, R.1
  • 15
    • 33745774771 scopus 로고    scopus 로고
    • Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload
    • Piga A et al. Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload. Haematologica 2006; 91: 873–880.
    • (2006) Haematologica , vol.91 , pp. 873-880
    • Piga, A.1
  • 16
    • 84878521432 scopus 로고    scopus 로고
    • Pharmacogenetic study of deferasirox, an iron chelating agent
    • Lee JW et al. Pharmacogenetic study of deferasirox, an iron chelating agent. PLoS One 2013; 8: e64114.
    • (2013) PLoS One , vol.8
    • Lee, J.W.1
  • 18
    • 84929959628 scopus 로고    scopus 로고
    • Influence of single-nucleotide polymorphisms on deferasirox C trough levels and effectiveness
    • Cusato J et al. Influence of single-nucleotide polymorphisms on deferasirox C trough levels and effectiveness. Pharmacogenomics J 2015; 15: 263–271.
    • (2015) Pharmacogenomics J , vol.15 , pp. 263-271
    • Cusato, J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.