Vitamin D expenditure is not altered in pregnancy and lactation despite changes in Vitamin D metabolite concentrations

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Jones, Kerry S ^a,b   Assar, Shima ^a   Prentice, Ann ^a,b   Schoenmakers, Inez ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIFEDIOL; PARATHYROID HORMONE; VITAMIN D; VITAMIN D BINDING PROTEIN;

ADULT; BLOOD; COMPARATIVE STUDY; CROSS-SECTIONAL STUDY; DIET; FEMALE; FOLLOW UP; GAMBIA; HALF LIFE TIME; HOMEOSTASIS; HUMAN; LACTATION; METABOLISM; PREGNANCY; PROSPECTIVE STUDY; SUNLIGHT; YOUNG ADULT;

ADULT; CALCIFEDIOL; CROSS-SECTIONAL STUDIES; DIET; FEMALE; FOLLOW-UP STUDIES; GAMBIA; HALF-LIFE; HOMEOSTASIS; HUMANS; LACTATION; PARATHYROID HORMONE; PREGNANCY; PROSPECTIVE STUDIES; SUNLIGHT; VITAMIN D; VITAMIN D-BINDING PROTEIN; YOUNG ADULT;

EID: 84971268073     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep26795     Document Type: Article

References (57)

1. Prentice, A. Maternal calcium metabolism and bone mineral status. Am J Clin Nutr 71, 1312S-1316 (2000).
2. Institute of Medicine. Dietary reference intakes for calcium and vitamin D. (The National Academies Press, 2011).
3. Brannon, P. M., Picciano, M. F. Vitamin D in pregnancy and lactation in humans. Annu Rev Nutr 31, 89-115, doi: 10.1146/annurev. nutr.012809.104807 (2011).
4. Papapetrou, P. D. The interrelationships of serum 1,25-dihydroxyvitamin D, 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D in pregnancy at term: a meta-analysis. Hormones 9, 136-144 (2010).
5. Cross, N. A., Hillman, L. S., Allen, S. H., Krause, G. F., Vieira, N. E. Calcium homeostasis and bone metabolism during pregnancy, lactation, and postweaning: a longitudinal study. Am J Clin Nutr 61, 514-523 (1995).
6. Zhang, J. Y., Lucey, A. J., Horgan, R., Kenny, L. C., Kiely, M. Impact of pregnancy on vitamin D status: a longitudinal study. Br J Nutr 112, 1081-1087 doi: 10.1017/s0007114514001883 (2014).
7. Clements, M. R., Johnson, L., Fraser, D. R. A new mechanism for induced vitamin D deficiency in calcium deprivation. Nature 325, 62-65, doi: 10.1038/325062a0 (1987).
8. Clements, M. R. et al. The role of 1,25-dihydroxyvitamin D in the mechanism of acquired vitamin D deficiency. Clin Endocrinol 37, 17-27, doi: 10.1111/j.1365-2265.1992.tb02278.x (1992).
9. Davies, M., Heys, S. E., Selby, P. L., Berry, J. L., Mawer, E. B. Increased catabolism of 25-hydroxyvitamin D in patients with partial gastrectomy and elevated 1,25-dihydroxyvitamin D levels. Implications for metabolic bone disease. J Clin Endocrinol Metab 82, 209-212, doi: 10.1210/jcem.82.1.3644 (1997).
10. Vieth, R., Fraser, D., Kooh, S. W. Low dietary calcium reduces 25-hydroxycholecalciferol in plasma of rats. J Nutr 117, 914-918 (1987).
11. Kovacs, C. S. Vitamin D in pregnancy and lactation: maternal, fetal, and neonatal outcomes from human and animal studies. Am J Clin Nutr 88, 520S-528S (2008).
12. Clements, M. R., Fraser, D. R. Vitamin D supply to the rat fetus and neonate. J Clin Invest 81, 1768-1773, doi: 10.1172/JCI113518 (1988).
13. Dawes, M., Chowienczyk, P. J. Pharmacokinetics in pregnancy. Best Pract Res Clin Obstet Gynaecol 15, 819-826, doi: 10.1053/beog.2001.0231 (2001).
14. Prentice, A., Goldberg, G. R., Schoenmakers, I. Vitamin D across the lifecycle: physiology and biomarkers. Am J Clin Nutr 88, 500S-506S (2008).
15. Schoenmakers, I. et al. Prevention and consequences of vitamin D deficiency in pregnant and lactating women and children: A symposium to prioritise vitamin D on the global agenda. J Steroid Biochem Mol Biol, doi: 10.1016/j.jsbmb.2015.11.004 (2015).
16. WHO. Guideline: Vitamin D supplementation in pregnant women. (World Health Organisation, 2012).
17. Spiro, A., Buttriss, J. L. Vitamin D: An overview of vitamin D status and intake in Europe. Nutr Bull 39, 322-350, doi: 10.1111/nbu.12108 (2014).
18. SACN. Draft Vitamin D and Health Report. (Scientific Advisory Committee on Nutrition, 2015).
19. Harvey, N. C. et al. Vitamin D supplementation in pregnancy: a systematic review. Health Technol Assess 18, 1-190, doi: 10.3310/hta18450 (2014).
20. Harvey, N. et al. MAVIDOS Maternal Vitamin D Osteoporosis Study: study protocol for a randomized controlled trial. Trials 13, 13 (2012).
21. Jones, K. S. et al. Predictors of 25(OH)D half-life and plasma 25(OH)D concentration in The Gambia and the UK. Osteoporos Int 26, 1137-1146, doi: 10.1007/s00198-014-2905-0 (2015).
22. Jones, K. S. et al. 25(OH)D2 half-life is shorter than 25(OH)D3 half-life and is influenced by DBP concentration and genotype. J Clin Endocrinol Metab 99, 3373-3381, doi: 10.1210/jc.2014-1714 (2014).
23. Prentice, A. et al. The calcium and phosphorus intakes of rural Gambian women during pregnancy and lactation. Br J Nutr 69, 885-896 (1993).
24. Prentice, A. Vitamin D deficiency: a global perspective. Nutr Rev 66, S153-164, doi: 10.1111/j.1753-4887.2008.00100.x (2008).
25. Schoenmakers, I. et al. Acute response to oral calcium loading in pregnant and lactating women with a low calcium intake: a pilot study. Osteoporos Int 24, 2301-2308, doi: 10.1007/s00198-013-2280-2 (2013).
26. Kirby, B. J. et al. Upregulation of calcitriol during pregnancy and skeletal recovery after lactation do not require parathyroid hormone. J Bone Miner Res 28, 1987-2000, doi: 10.1002/jbmr.1925 (2013).
27. Horwitz, M. J. et al. Continuous PTH and PTHrP infusion causes suppression of bone formation and discordant effects on 1,25(OH)2 vitamin D. J Bone Miner Res 20, 1792-1803, doi: 10.1359/jbmr.050602 (2005).
28. Kovacs, C. S. Maternal vitamin D deficiency: Fetal and neonatal implications. Semin Fetal Neonatal Med 18, 129-135, doi: 10.1016/j. siny.2013.01.005 (2013).
29. Møller, U. K. et al. Increased plasma concentrations of vitamin D metabolites and vitamin D binding protein in women using hormonal contraceptives: a cross-sectional study. Nutrients 5, 3470-3480, doi: 10.3390/nu5093470 (2013).
30. Holt, E., Wysolmerski, J. J. In Vitamin D (eds Feldman, D., Pike, J. W., Adams, J. S.) Ch. 41, 725-745 (Elsevier, 2011).
31. Wagner, D. et al. The ratio of serum 24,25-dihydroxyvitamin D3 to 25-hydroxyvitamin D3 is predictive of 25-hydroxyvitamin D3 response to vitamin D3 supplementation. J Steroid Biochem Mol Biol 126, 72-77, doi: 10.1016/j.jsbmb.2011.05.003 (2011).
32. Prentice, A. Calcium in pregnancy and lactation. Ann Rev Nutr 20, 249-272, doi: 10.1146/annurev.nutr.20.1.249 (2000).
33. Novakovic, B. et al. Placenta-specific methylation of the vitamin D 24-hydroxylase gene: Implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface. J Biol Chem 284, 14838-14848, doi: 10.1074/jbc.M809542200 (2009).
34. Luxwolda, M. F. et al. Vitamin D status indicators in indigenous populations in East Africa. Eur J Nutr 52, 1115-1125, doi: 10.1007/s00394-012-0421-6 (2013).
35. Kent, G. N. et al. Human lactation: forearm trabecular bone loss, increased bone turnover, and renal conservation of calcium and inorganic phosphate with recovery of bone mass following weaning. J Bone Miner Res 5, 361-369, doi: 10.1002/jbmr.5650050409 (1990).
36. Møller, U. K., Streym, S., Heickendorff, L., Mosekilde, L., Rejnmark, L. Effects of 25OHD concentrations on chances of pregnancy and pregnancy outcomes: a cohort study in healthy Danish women. Eur J Clin Nutr 66, 862-868, doi: 10.1038/ejcn.2012.18 (2012).
37. Prentice, A. In Pediatric Bone (eds Glorieux, F. H., Pettifor, J. M., Juppner, H.) Ch. 10, 223-246 (Academic Press, 2011).
38. Chun, R. F. et al. Vitamin D and DBP: The free hormone hypothesis revisited. J Steroid Biochem Mol Biol 144, 132-137, doi: 10.1016/j.jsbmb.2013.09.012 (2014).
39. Schwartz, J. B. et al. A comparison of measured and calculated free 25(OH) vitamin D levels in clinical populations. J Clin Endocrinol Metab 99, 1631-1637, doi: 10.1210/jc.2013-3874 (2014).
40. Nielson, C. M. et al. Role of Assay Type in Determining Free 25-Hydroxyvitamin D Levels in Diverse Populations. N Engl J Med 374, 1695-1696, doi: 10.1056/NEJMc1513502 (2016).
41. Schwartz, J. B. et al. Variability in free 25(OH) vitamin D levels in clinical populations. J Steroid Biochem Mol Biol 144 Pt A, 156-158, doi: 10.1016/j.jsbmb.2013.11.006 (2014).
42. Bikle, D. D., Gee, E., Halloran, B., Haddad, J. G. Free 1,25-dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver disease. J Clin Invest 74, 1966-1971, doi: 10.1172/jci111617 (1984).
43. FAO/WHO/UNU. Human energy requirements (2001).
44. Prentice, A. M., Whitehead, R. G., Roberts, S. B., Paul, A. A. Long-term energy balance in child-bearing Gambian women. Am J Clin Nutr 34, 2790-2799 (1981).
45. Poppitt, S. D., Prentice, A. M., Jéquier, E., Schutz, Y., Whitehead, R. G. Evidence of energy sparing in Gambian women during pregnancy: a longitudinal study using whole-body calorimetry. Am J Clin Nutr 57, 353-364 (1993).
46. Johnson, W. et al. Impact of a prenatal lipid-based nutritional supplement on fetal growth in rural Gambia: the Early Nutrition and Immune Development trial (ISRCTN49285450). Matern Child Health (2016).
47. Jarjou, L. M. et al. Randomized, placebo-controlled, calcium supplementation study in pregnant Gambian women: effects on breastmilk calcium concentrations and infant birth weight, growth, and bone mineral accretion in the first year of life Am J Clin Nutr 83, 657-666 (2006).
48. Kambou, M. I., Ferrell, R. E. Ethnic variation in vitamin D-binding protein (GC): a review of isoelectric focusing studies in human populations. Hum Genet 72, 281-293 (1986).
49. Jones, K. S., Schoenmakers, I., Bluck, L. J., Ding, S., Prentice, A. Plasma appearance and disappearance of an oral dose of 25-hydroxyvitamin D2 in healthy adults. Br J Nutr 107, 1128-1137, doi: 10.1017/S0007114511004132 (2012).
50. Hennig, B. J. et al. Cohort Profile: The Kiang West Longitudinal Population Study (KWLPS)-a platform for integrated research and health care provision in rural Gambia. Int J Epidemiol, doi: 10.1093/ije/dyv206 (2015).
51. Moore, S. E. et al. A randomized trial to investigate the effects of pre-natal and infant nutritional supplementation on infant immune development in rural Gambia: the ENID trial: Early Nutrition and Immune Development. BMC Pregnancy Childbirth 12, 107, doi: 10.1186/1471-2393-12-107 (2012).
52. Fitt, E. et al. DINO (Diet In Nutrients Out)-an integrated dietary assessment system. Public Health Nutr 18, 234-241, doi: 10.1017/S1368980014000342 (2015).
53. Prynne, C., Paul, A. A. Food composition table for use in The Gambia. (MRC Human Nutrition Research, 2007).
54. Schoenmakers, I. et al. Interrelation of parathyroid hormone and vitamin D metabolites in adolescents from the UK and The Gambia. J Steroid Biochem Mol Biol 121, 217-220, doi: 10.1016/j.jsbmb.2010.03.012 (2010).
55. Tietz, N. W. Clinical Guide to Laboratory Tests. Second Edition, (W. B. Saunders Company, 1990).
56. Broadus, A. E., Mahaffey, J. E., Bartter, F. C., Neer, R. M. Nephrogenous cyclic adenosine monophosphate as a parathyroid function test. J Clin Invest 60, 771-783, doi: 10.1172/jci108831 (1977).
57. Mitchell, M. N. Interpreting and visualizing regression models using Stata. (Stata Press, 2012).