Synthesis and biological evaluation of 5,7-dihydroxyflavanone derivatives as antimicrobial agents

Bioorganic and Medicinal Chemistry Letters

Volumn 26, Issue 13, 2016, Pages 3089-3092

  Zhang, Xing ^a   Khalidi, Omar ^b   Kim, So Young ^c   Wang, Ruitong ^a   Schultz, Victor ^a   Cress, Brady F ^b   Gross, Richard A ^a,b,c   Koffas, Mattheos A G ^b,c   Linhardt, Robert J ^a,b,c  

^a Rensselaer Polytechnic Institute   (United States)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^c RENSSELAER POLYTECHNIC INSTITUTE   (United States)

Author keywords

Antimicrobial activity; Cytotoxicity; Halogenated flavanones; Synthesis

Indexed keywords

ACETIC ACID; ANTIINFECTIVE AGENT; BENZALDEHYDE DERIVATIVE; PINOCEMBRINE; ANTIFUNGAL AGENT; ANTINEOPLASTIC AGENT; FLAVANONE DERIVATIVE;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS ANTHRACIS; BACILLUS CEREUS; BACILLUS SUBTILIS; CARBON NUCLEAR MAGNETIC RESONANCE; CELL VIABILITY ASSAY; COLUMN CHROMATOGRAPHY; CYTOTOXICITY; DRUG EFFICACY; DRUG SCREENING; DRUG SYNTHESIS; ESCHERICHIA COLI; HALOGENATION; HEPG2 CELL LINE; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; PSEUDOMONAS AERUGINOSA; SACCHAROMYCES CEREVISIAE; STAPHYLOCOCCUS AUREUS; VIBRIO CHOLERAE; CELL PROLIFERATION; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HEP-G2 CELL LINE; MICROBIAL SENSITIVITY TEST; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FLAVANONES; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HEP G2 CELLS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; SACCHAROMYCES CEREVISIAE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84971249136     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2016.05.003     Document Type: Article

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