메뉴 건너뛰기




Volumn 79, Issue 6, 2016, Pages 929-939

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

(32)  Lee, Seonjoo a,b   Viqar, Fawad a,c   Zimmerman, Molly E c,d   Narkhede, Atul a   Tosto, Giuseppe a,e   Benzinger, Tammie L S f   Marcus, Daniel S f   Fagan, Anne M g   Goate, Alison h   Fox, Nick C i   Cairns, Nigel J g   Holtzman, David M g   Buckles, Virginia g   Ghetti, Bernardino j   McDade, Eric g   Martins, Ralph N k   Saykin, Andrew J j   Masters, Colin L l   Ringman, John M m   Ryan, Natalie S i   more..


Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; PRESENILIN 1; PRESENILIN 2; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); BIOLOGICAL MARKER; MAPT PROTEIN, HUMAN; PEPTIDE FRAGMENT; PSEN1 PROTEIN, HUMAN; PSEN2 PROTEIN, HUMAN; TAU PROTEIN;

EID: 84971222625     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.24647     Document Type: Article
Times cited : (406)

References (51)
  • 1
    • 77955360281 scopus 로고    scopus 로고
    • The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: Systematic review and meta-analysis
    • Debette S, Markus HS,. The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ. 2010; 341: c3666.
    • (2010) BMJ. , vol.341 , pp. c3666
    • Debette, S.1    Markus, H.S.2
  • 2
    • 85018195216 scopus 로고    scopus 로고
    • What are white matter hyperintensities made of? Relevance to vascular cognitive impairment
    • Wardlaw JM, Valdés Hernández MC, Muñoz-Maniega S,. What are white matter hyperintensities made of? Relevance to vascular cognitive impairment. J Am Heart Assoc 2015; 4: 001140.
    • (2015) J Am Heart Assoc , vol.4 , pp. 001140
    • Wardlaw, J.M.1    Valdés Hernández, M.C.2    Muñoz-Maniega, S.3
  • 3
    • 84886739727 scopus 로고    scopus 로고
    • Contemplating Alzheimer's disease and the contribution of white matter hyperintensities
    • Brickman AM,. Contemplating Alzheimer's disease and the contribution of white matter hyperintensities. Curr Neurol Neurosci Rep 2013; 13: 415.
    • (2013) Curr Neurol Neurosci Rep , vol.13 , pp. 415
    • Brickman, A.M.1
  • 4
    • 84872379077 scopus 로고    scopus 로고
    • Tracking pathophysiological processes in Alzheimer's disease: An updated hypothetical model of dynamic biomarkers
    • Jack CR, Jr., Knopman DS, Jagust WJ, et al., Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol 2013; 12: 207-216.
    • (2013) Lancet Neurol , vol.12 , pp. 207-216
    • Jack, C.R.1    Knopman, D.S.2    Jagust, W.J.3
  • 5
    • 84940467112 scopus 로고    scopus 로고
    • White matter signal abnormality quality differentiates mild cognitive impairment that converts to Alzheimer's disease from nonconverters
    • Alzheimer's Disease Neuroimaging Initiative.
    • Lindemer ER, Salat DH, Smith EE, et al.,; Alzheimer's Disease Neuroimaging Initiative. White matter signal abnormality quality differentiates mild cognitive impairment that converts to Alzheimer's disease from nonconverters. Neurobiol Aging 2015; 6: 2447-2457.
    • (2015) Neurobiol Aging , vol.6 , pp. 2447-2457
    • Lindemer, E.R.1    Salat, D.H.2    Smith, E.E.3
  • 6
    • 84871243398 scopus 로고    scopus 로고
    • Regional white matter hyperintensity volume, not hippocampal atrophy, predicts incident Alzheimer disease in the community
    • Brickman AM, Provenzano FA, Muraskin J, et al., Regional white matter hyperintensity volume, not hippocampal atrophy, predicts incident Alzheimer disease in the community. Arch Neurol 2012; 69: 1621-1627.
    • (2012) Arch Neurol , vol.69 , pp. 1621-1627
    • Brickman, A.M.1    Provenzano, F.A.2    Muraskin, J.3
  • 7
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders
    • Zlokovic BV,. Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders. Nat Rev Neurosci 2011; 12: 723-738.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 723-738
    • Zlokovic, B.V.1
  • 8
    • 75149115045 scopus 로고    scopus 로고
    • Brain lesions at autopsy in older Japanese-American men as related to cognitive impairment and dementia in the final years of life: A summary report from the Honolulu-Asia aging study
    • White L,. Brain lesions at autopsy in older Japanese-American men as related to cognitive impairment and dementia in the final years of life: a summary report from the Honolulu-Asia aging study. J Alzheimers Dis 2009; 18: 713-725.
    • (2009) J Alzheimers Dis , vol.18 , pp. 713-725
    • White, L.1
  • 9
    • 35748959415 scopus 로고    scopus 로고
    • Mixed brain pathologies account for most dementia cases in community-dwelling older persons
    • Schneider JA, Arvanitakis Z, Bang W, Bennett DA,. Mixed brain pathologies account for most dementia cases in community-dwelling older persons. Neurology 2007; 69: 2197-2204.
    • (2007) Neurology , vol.69 , pp. 2197-2204
    • Schneider, J.A.1    Arvanitakis, Z.2    Bang, W.3    Bennett, D.A.4
  • 10
    • 84934291197 scopus 로고    scopus 로고
    • Neuropathologic assessment of participants in two multi-center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN)
    • Cairns NJ, Perrin RJ, Franklin EE, et al., Neuropathologic assessment of participants in two multi-center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN). Neuropathology 2015; 35: 390-400.
    • (2015) Neuropathology , vol.35 , pp. 390-400
    • Cairns, N.J.1    Perrin, R.J.2    Franklin, E.E.3
  • 11
    • 84865529158 scopus 로고    scopus 로고
    • Clinical and biomarker changes in dominantly inherited Alzheimer's disease
    • Bateman RJ, Xiong C, Benzinger TL, et al., Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med 2012; 367: 795-804.
    • (2012) N Engl J Med , vol.367 , pp. 795-804
    • Bateman, R.J.1    Xiong, C.2    Benzinger, T.L.3
  • 12
    • 84905868699 scopus 로고    scopus 로고
    • Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis
    • Ryman DC, Acosta-Baena N, Aisen PS, et al., Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis. Neurology 2014; 83: 253-260.
    • (2014) Neurology , vol.83 , pp. 253-260
    • Ryman, D.C.1    Acosta-Baena, N.2    Aisen, P.S.3
  • 13
    • 84878794559 scopus 로고    scopus 로고
    • Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network
    • Morris JC, Aisen PS, Bateman RJ, et al., Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clin Investig (Lond) 2012; 2: 975-984.
    • (2012) Clin Investig (Lond) , vol.2 , pp. 975-984
    • Morris, J.C.1    Aisen, P.S.2    Bateman, R.J.3
  • 14
    • 0030859067 scopus 로고    scopus 로고
    • Clinical dementia rating training and reliability in multicenter studies: The Alzheimer's Disease Cooperative Study experience
    • Morris JC, Ernesto C, Schafer K, et al., Clinical dementia rating training and reliability in multicenter studies: the Alzheimer's Disease Cooperative Study experience. Neurology 1997; 48: 1508-1510.
    • (1997) Neurology , vol.48 , pp. 1508-1510
    • Morris, J.C.1    Ernesto, C.2    Schafer, K.3
  • 15
    • 77954623809 scopus 로고    scopus 로고
    • Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative
    • Jack CR, Jr., Bernstein MA, Borowski BJ, et al., Update on the magnetic resonance imaging core of the Alzheimer's disease neuroimaging initiative. Alzheimers Dement 2010; 6: 212-220.
    • (2010) Alzheimers Dement , vol.6 , pp. 212-220
    • Jack, C.R.1    Bernstein, M.A.2    Borowski, B.J.3
  • 16
    • 84920406414 scopus 로고    scopus 로고
    • Reconsidering harbingers of dementia: Progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence
    • Brickman AM, Zahodne LB, Guzman VA, et al., Reconsidering harbingers of dementia: progression of parietal lobe white matter hyperintensities predicts Alzheimer's disease incidence. Neurobiol Aging 2015; 36: 27-32.
    • (2015) Neurobiol Aging , vol.36 , pp. 27-32
    • Brickman, A.M.1    Zahodne, L.B.2    Guzman, V.A.3
  • 17
    • 0035957075 scopus 로고    scopus 로고
    • Clinical diagnosis of cerebral amyloid angiopathy: Validation of the Boston criteria
    • Knudsen KA, Rosand J, Karluk D, Greenberg SM,. Clinical diagnosis of cerebral amyloid angiopathy: validation of the Boston criteria. Neurology 2001; 56: 537-539.
    • (2001) Neurology , vol.56 , pp. 537-539
    • Knudsen, K.A.1    Rosand, J.2    Karluk, D.3    Greenberg, S.M.4
  • 19
    • 67349093182 scopus 로고    scopus 로고
    • Selecting the number of change-points in segmented line regression
    • Kim HJ, Yu B, Feuer EJ,. Selecting the number of change-points in segmented line regression. Stat Sin 2009; 19: 597-609.
    • (2009) Stat Sin , vol.19 , pp. 597-609
    • Kim, H.J.1    Yu, B.2    Feuer, E.J.3
  • 20
    • 0041568268 scopus 로고    scopus 로고
    • Inference for the break point in segmented regression with application to longitudinal data
    • Piepho HP, Ogutu JO,. Inference for the break point in segmented regression with application to longitudinal data. Biometr J 2003; 45: 591-601.
    • (2003) Biometr J , vol.45 , pp. 591-601
    • Piepho, H.P.1    Ogutu, J.O.2
  • 21
    • 84936916896 scopus 로고
    • Robust locally-weighted regression and smoothing scatterplots
    • Cleveland WS,. Robust locally-weighted regression and smoothing scatterplots. J Am Stat Assoc 1979; 74: 829-836.
    • (1979) J Am Stat Assoc , vol.74 , pp. 829-836
    • Cleveland, W.S.1
  • 22
    • 0001118346 scopus 로고
    • Alternative transformations to handle extreme values of the dependent variable
    • Burbridge JB, Magee L, Robb AL,. Alternative transformations to handle extreme values of the dependent variable. J Am Stat Assoc 1988; 83: 123-127.
    • (1988) J Am Stat Assoc , vol.83 , pp. 123-127
    • Burbridge, J.B.1    Magee, L.2    Robb, A.L.3
  • 23
    • 84924650926 scopus 로고    scopus 로고
    • White matter hyperintensities, cognitive impairment and dementia: An update
    • Prins ND, Scheltens P,. White matter hyperintensities, cognitive impairment and dementia: an update. Nat Rev Neurol 2015; 11: 157-165.
    • (2015) Nat Rev Neurol , vol.11 , pp. 157-165
    • Prins, N.D.1    Scheltens, P.2
  • 24
    • 84924255910 scopus 로고    scopus 로고
    • Cerebral autoregulation, beta amyloid, and white matter hyperintensities are interrelated
    • Brickman AM, Guzman VA, Gonzalez-Castellon M, et al., Cerebral autoregulation, beta amyloid, and white matter hyperintensities are interrelated. Neurosci Lett 2015; 592: 54-58.
    • (2015) Neurosci Lett , vol.592 , pp. 54-58
    • Brickman, A.M.1    Guzman, V.A.2    Gonzalez-Castellon, M.3
  • 25
    • 84866744392 scopus 로고    scopus 로고
    • White matter hyperintensities predict amyloid increase in Alzheimer's disease
    • Grimmer T, Faust M, Auer F, et al., White matter hyperintensities predict amyloid increase in Alzheimer's disease. Neurobiol Aging 2012; 33: 2766-2773.
    • (2012) Neurobiol Aging , vol.33 , pp. 2766-2773
    • Grimmer, T.1    Faust, M.2    Auer, F.3
  • 26
    • 84919402734 scopus 로고    scopus 로고
    • White matter lesion load is associated with resting state functional MRI activity and amyloid PET but not FDG in mild cognitive impairment and early Alzheimer's disease patients
    • Zhou Y, Yu F, Duong TQ,. White matter lesion load is associated with resting state functional MRI activity and amyloid PET but not FDG in mild cognitive impairment and early Alzheimer's disease patients. J Magn Reson Imaging 2015; 41: 102-109.
    • (2015) J Magn Reson Imaging , vol.41 , pp. 102-109
    • Zhou, Y.1    Yu, F.2    Duong, T.Q.3
  • 27
    • 84927979900 scopus 로고    scopus 로고
    • Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly
    • Vemuri P, Lesnick TG, Przybelski SA, et al., Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly. Brain 2015; 138 (pt 3): 761-771.
    • (2015) Brain , vol.138 , pp. 761-771
    • Vemuri, P.1    Lesnick, T.G.2    Przybelski, S.A.3
  • 28
    • 84952630634 scopus 로고    scopus 로고
    • The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment
    • Alzheimer's Disease Neuroimaging Initiative.
    • Tosto G, Zimmerman ME, Hamilton JL, Carmichael OT, Brickman AM,; Alzheimer's Disease Neuroimaging Initiative. The effect of white matter hyperintensities on neurodegeneration in mild cognitive impairment. Alzheimers Dement 2015; 11: 1510-1519.
    • (2015) Alzheimers Dement , vol.11 , pp. 1510-1519
    • Tosto, G.1    Zimmerman, M.E.2    Hamilton, J.L.3    Carmichael, O.T.4    Brickman, A.M.5
  • 29
    • 84884574818 scopus 로고    scopus 로고
    • Neuropathologic basis of white matter hyperintensity accumulation with advanced age
    • Erten-Lyons D, Woltjer R, Kaye J, et al., Neuropathologic basis of white matter hyperintensity accumulation with advanced age. Neurology 2013; 81: 977-983.
    • (2013) Neurology , vol.81 , pp. 977-983
    • Erten-Lyons, D.1    Woltjer, R.2    Kaye, J.3
  • 30
    • 84961290507 scopus 로고    scopus 로고
    • Pathological correlates of white matter hyperintensities on magnetic resonance imaging
    • Shim YS, Yang DW, Roe CM, et al., Pathological correlates of white matter hyperintensities on magnetic resonance imaging. Dement Geriatr Cogn Disord 2015; 39: 92-104.
    • (2015) Dement Geriatr Cogn Disord , vol.39 , pp. 92-104
    • Shim, Y.S.1    Yang, D.W.2    Roe, C.M.3
  • 31
    • 84942844748 scopus 로고    scopus 로고
    • Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI
    • Verhaaren BF, Debette S, Bis JC, et al., Multiethnic genome-wide association study of cerebral white matter hyperintensities on MRI. Circ Cardiovasc Genet 2015; 8: 398-409.
    • (2015) Circ Cardiovasc Genet , vol.8 , pp. 398-409
    • Verhaaren, B.F.1    Debette, S.2    Bis, J.C.3
  • 32
    • 84947017996 scopus 로고    scopus 로고
    • Genetic determinants of white matter hyperintensities and amyloid angiopathy in familial Alzheimer's disease
    • Ryan NS, Biessels GJ, Kim L, et al., Genetic determinants of white matter hyperintensities and amyloid angiopathy in familial Alzheimer's disease. Neurobiol Aging 2015; 36: 3140-3151.
    • (2015) Neurobiol Aging , vol.36 , pp. 3140-3151
    • Ryan, N.S.1    Biessels, G.J.2    Kim, L.3
  • 33
    • 84921971768 scopus 로고    scopus 로고
    • Posterior white matter disease distribution as a predictor of amyloid angiopathy
    • Thanprasertsuk S, Martinez-Ramirez S, Pontes-Neto OM, et al., Posterior white matter disease distribution as a predictor of amyloid angiopathy. Neurology 2014; 83: 794-800.
    • (2014) Neurology , vol.83 , pp. 794-800
    • Thanprasertsuk, S.1    Martinez-Ramirez, S.2    Pontes-Neto, O.M.3
  • 34
    • 84878381489 scopus 로고    scopus 로고
    • Cerebral amyloid angiopathy burden associated with leukoaraiosis: A positron emission tomography/magnetic resonance imaging study
    • Gurol ME, Viswanathan A, Gidicsin C, et al., Cerebral amyloid angiopathy burden associated with leukoaraiosis: a positron emission tomography/magnetic resonance imaging study. Ann Neurol 2013; 73: 529-536.
    • (2013) Ann Neurol , vol.73 , pp. 529-536
    • Gurol, M.E.1    Viswanathan, A.2    Gidicsin, C.3
  • 35
    • 0035208657 scopus 로고    scopus 로고
    • Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures
    • Takao M, Ghetti B, Murrell JR, et al., Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures. J Neuropathol Exp Neurol 2001; 60: 1137-1152.
    • (2001) J Neuropathol Exp Neurol , vol.60 , pp. 1137-1152
    • Takao, M.1    Ghetti, B.2    Murrell, J.R.3
  • 36
    • 10044290352 scopus 로고    scopus 로고
    • Detection of age-dependent brain injury in a mouse model of brain amyloidosis associated with Alzheimer's disease using magnetic resonance diffusion tensor imaging
    • Sun SW, Song SK, Harms MP, et al., Detection of age-dependent brain injury in a mouse model of brain amyloidosis associated with Alzheimer's disease using magnetic resonance diffusion tensor imaging. Exp Neurol 2005; 191: 77-85.
    • (2005) Exp Neurol , vol.191 , pp. 77-85
    • Sun, S.W.1    Song, S.K.2    Harms, M.P.3
  • 37
    • 85048245848 scopus 로고    scopus 로고
    • Soluble amyloid beta levels are elevated in the white matter of Alzheimer's patients, independent of cortical plaque burden
    • Collins-Praino L, Francis Y, Wiegman AF, et al., Soluble amyloid beta levels are elevated in the white matter of Alzheimer's patients, independent of cortical plaque burden. Acta Neuropathol Commun 2014; 2: 83.
    • (2014) Acta Neuropathol Commun , vol.2 , pp. 83
    • Collins-Praino, L.1    Francis, Y.2    Wiegman, A.F.3
  • 38
    • 0037450356 scopus 로고    scopus 로고
    • PDAPP; YFP double transgenic mice: A tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures
    • Brendza RP, O'Brien C, Simmons K, et al., PDAPP; YFP double transgenic mice: a tool to study amyloid-beta associated changes in axonal, dendritic, and synaptic structures. J Comp Neurol 2003; 456: 375-383.
    • (2003) J Comp Neurol , vol.456 , pp. 375-383
    • Brendza, R.P.1    O'Brien, C.2    Simmons, K.3
  • 39
    • 84871268904 scopus 로고    scopus 로고
    • Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men
    • Behrendt G, Baer K, Buffo A, et al., Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men. Glia 2013; 61: 273-286.
    • (2013) Glia , vol.61 , pp. 273-286
    • Behrendt, G.1    Baer, K.2    Buffo, A.3
  • 40
    • 0028326935 scopus 로고
    • Visual cortex in Alzheimer's disease: Occurrence of neuronal death and glial proliferation, and correlation with pathological hallmarks
    • Leuba G, Kraftsik R,. Visual cortex in Alzheimer's disease: occurrence of neuronal death and glial proliferation, and correlation with pathological hallmarks. Neurobiol Aging 1994; 15: 29-43.
    • (1994) Neurobiol Aging , vol.15 , pp. 29-43
    • Leuba, G.1    Kraftsik, R.2
  • 41
    • 80052846665 scopus 로고    scopus 로고
    • Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease
    • Reddy PH,. Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease. Brain Res 2011; 1415: 136-148.
    • (2011) Brain Res , vol.1415 , pp. 136-148
    • Reddy, P.H.1
  • 42
    • 77953533246 scopus 로고    scopus 로고
    • Cerebral small vessel disease: From pathogenesis and clinical characteristics to therapeutic challenges
    • Pantoni L,. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 2010; 9: 689-701.
    • (2010) Lancet Neurol , vol.9 , pp. 689-701
    • Pantoni, L.1
  • 43
    • 11844288889 scopus 로고    scopus 로고
    • Measures of brain morphology and infarction in the framingham heart study: Establishing what is normal
    • DeCarli C, Massaro J, Harvey D, et al., Measures of brain morphology and infarction in the framingham heart study: establishing what is normal. Neurobiol Aging 2005; 26: 491-510.
    • (2005) Neurobiol Aging , vol.26 , pp. 491-510
    • DeCarli, C.1    Massaro, J.2    Harvey, D.3
  • 44
    • 80052400687 scopus 로고    scopus 로고
    • Vascular contributions to cognitive impairment and dementia: A statement for healthcare professionals from the American Heart Association/American stroke association
    • Gorelick PB, Scuteri A, Black SE, et al., Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association. Stroke 2011; 42: 2672-2713.
    • (2011) Stroke , vol.42 , pp. 2672-2713
    • Gorelick, P.B.1    Scuteri, A.2    Black, S.E.3
  • 45
    • 33745876233 scopus 로고    scopus 로고
    • Neuropathology of older persons without cognitive impairment from two community-based studies
    • Bennett DA, Schneider JA, Arvanitakis Z, et al., Neuropathology of older persons without cognitive impairment from two community-based studies. Neurology 2006; 66: 1837-1844.
    • (2006) Neurology , vol.66 , pp. 1837-1844
    • Bennett, D.A.1    Schneider, J.A.2    Arvanitakis, Z.3
  • 46
    • 55949117032 scopus 로고    scopus 로고
    • Frequent amyloid deposition without significant cognitive impairment among the elderly
    • Aizenstein HJ, Nebes RD, Saxton JA, et al., Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol 2008; 65: 1509-1517.
    • (2008) Arch Neurol , vol.65 , pp. 1509-1517
    • Aizenstein, H.J.1    Nebes, R.D.2    Saxton, J.A.3
  • 47
    • 84877285804 scopus 로고    scopus 로고
    • Acute and chronic traumatic encephalopathies: Pathogenesis and biomarkers
    • DeKosky ST, Blennow K, Ikonomovic MD Gandy S,. Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers. Nat Rev Neurol 2013; 9: 192-200.
    • (2013) Nat Rev Neurol , vol.9 , pp. 192-200
    • DeKosky, S.T.1    Blennow, K.2    Ikonomovic, M.D.3    Gandy, S.4
  • 48
    • 84922089484 scopus 로고    scopus 로고
    • Primary age-related tauopathy (PART): A common pathology associated with human aging
    • Crary JF, Trojanowski JQ, Schneider JA, et al., Primary age-related tauopathy (PART): a common pathology associated with human aging. Acta Neuropathol 2014; 128: 755-766.
    • (2014) Acta Neuropathol , vol.128 , pp. 755-766
    • Crary, J.F.1    Trojanowski, J.Q.2    Schneider, J.A.3
  • 50
    • 0026597219 scopus 로고
    • MR-based hippocampal volumetry in the diagnosis of Alzheimer's disease
    • Jack CR, Jr., Petersen RC, O'Brien PC, Tangalos EG,. MR-based hippocampal volumetry in the diagnosis of Alzheimer's disease. Neurology 1992; 42: 183-188.
    • (1992) Neurology , vol.42 , pp. 183-188
    • Jack, C.R.1    Petersen, R.C.2    O'Brien, P.C.3    Tangalos, E.G.4
  • 51
    • 23444441331 scopus 로고    scopus 로고
    • Regional brain changes in aging healthy adults: General trends, individual differences and modifiers
    • Raz N, Lindenberger U, Rodrigue KM, et al., Regional brain changes in aging healthy adults: general trends, individual differences and modifiers. Cereb Cortex 2005; 15: 1676-1689.
    • (2005) Cereb Cortex , vol.15 , pp. 1676-1689
    • Raz, N.1    Lindenberger, U.2    Rodrigue, K.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.