Respiratory syncytial virus infection down-regulates antioxidant enzyme expression by triggering deacetylation-proteasomal degradation of Nrf2

Free Radical Biology and Medicine

Volumn 88, Issue Part B, 2015, Pages 391-403

  Komaravelli, Narayana ^a   Tian, Bing ^a   Ivanciuc, Teodora ^a   Mautemps, Nicholas ^a   Brasier, Allan R ^a,b   Garofalo, Roberto P ^a   Casola, Antonella ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Acetylation; Antioxidant enzymes; Nrf2; Oxidative stress; Proteasome; Respiratory syncytial virus; ROS

Indexed keywords

ANTIOXIDANT ENZYME; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; ENZYME; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; LACTACYSTIN; PROTEASOME; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; TRICHOSTATIN A; UNCLASSIFIED DRUG; ANTIOXIDANT;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEACETYLATION; DOWN REGULATION; ENZYME MECHANISM; FEMALE; HEP 2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REDUCTION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; IMMUNOPRECIPITATION; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DOWN-REGULATION; FEMALE; HUMANS; IMMUNOPRECIPITATION; MICE; MICE, INBRED BALB C; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84971013833     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.05.043     Document Type: Article

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