NFATc4 and myocardin synergistically up-regulate the expression of LTCC α1C in ET-1-induced cardiomyocyte hypertrophy

Life Sciences

Volumn 155, Issue , 2016, Pages 11-20

  Li, Man ^a   He, Hong Peng ^a   Gong, Hui Qin ^a   Zhang, Jian ^a   Ma, Wen Jian ^a   Zhou, Hao ^a   Cao, Dong Sun ^b   Wang, Nan ^a   Zhang, Tong Cun ^a,b  

^a TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Cardiomyocyte hypertrophy; Endothelin 1; L type Ca2 + channel; Myocardin; Nuclear factor of activated T cells c4

Indexed keywords

CALCINEURIN; CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL L TYPE ALPHA 1C SUBUNIT; CYCLOSPORIN A; ENDOTHELIN 1; MYOCARDIN; TRANSCRIPTION FACTOR NFAT; TRANSCRIPTION FACTOR NFATC4; UNCLASSIFIED DRUG; VERAPAMIL; NERVE PROTEIN; NFATC4 PROTEIN, RAT; NUCLEAR PROTEIN; TRANSACTIVATOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOINFORMATICS; CARDIAC MUSCLE CELL; CELL NUCLEUS; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; GENE OVEREXPRESSION; GENE SILENCING; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; NEWBORN; NONHUMAN; PHARMACOLOGICAL BLOCKING; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RAT; RNA INTERFERENCE; TRANSACTIVATION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; CELL CULTURE; HEK293 CELL LINE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; ENDOTHELIN-1; HEK293 CELLS; HUMANS; MYOCYTES, CARDIAC; NERVE TISSUE PROTEINS; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; UP-REGULATION;

EID: 84970978709     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2016.05.007     Document Type: Article

References (45)

1. J. Heineke, and J.D. Molkentin Regulation of cardiac hypertrophy by intracellular signalling pathways Nat. Rev. Mol. Cell Biol. 7 8 2006 589 600
2. R.D. Harvey, and J.W. Hell CaV1.2 signaling complexes in the heart J. Mol. Cell. Cardiol. 58 2013 143 152
3. R.M. Shaw, and H.M. Colecraft L-type calcium channel targeting and local signalling in cardiac myocytes Cardiovasc. Res. 98 2 2013 177 186
4. E. Cingolani, G.A. Ramirez Correa, and E. Kizana Gene therapy to inhibit the calcium channel beta subunit: physiological consequences and pathophysiological effects in models of cardiac hypertrophy Circ. Res. 101 2 2007 166 175
5. K. Ikeda, K. Tojo, and G. Tokudome Possible involvement of endothelin-1 in cardioprotective effects of benidipine Hypertens. Res. 23 5 2000 491 496
6. 2 + channels suppresses activation of calcineurin and development of cardiac hypertrophy in spontaneously hypertensive rats Hypertens. Res. 25 1 2002 117 124
7. E.C. Keung Calcium current is increased in isolated adult myocytes from hypertrophied rat myocardium Circ. Res. 64 4 1989 753 763
8. T.J. Kamp, and J.W. Hell Regulation of cardiac L-type calcium channels by protein kinase A and protein kinase C Circ. Res. 87 12 2000 1095 1102
9. G.S. Pitt, W. Dun, and P.A. Boyden Remodeled cardiac calcium channels J. Mol. Cell. Cardiol. 41 3 2006 373 388
10. L. Yang, G. Liu, and S.I. Zakharov Protein kinase G phosphorylates Cav1.2 alpha1c and beta2 subunits Circ. Res. 101 5 2007 465 474
11. D.D. Hall, J.A. Feekes, and A.S. Arachchige Don Binding of protein phosphatase 2A to the L-type calcium channel Cav1.2 next to Ser1928, its main PKA site, is critical for Ser1928 dephosphorylation Biochemistry 45 10 2006 3448 3459
12. 2 + channel Circ. Res. 105 1 2009 51 60
13. S.F. Liou, J.H. Hsu, and Y.T. Chen KMUP-1 attenuates endothelin-1-induced cardiomyocyte hypertrophy through activation of heme oxygenase-1 and suppression of the Akt/GSK-3β, calcineurin/NFATc4 and RhoA/ROCK pathways Molecules 20 6 2015 10435 10449
14. H. Li, S. Gao, and J. Ye COX-2 is involved in ET-1-induced hypertrophy of neonatal rat cardiomyocytes: role of NFATc3 Mol. Cell. Endocrinol. 382 2 2014 998 1006
15. K. Le, R. Li, and S. Xu PPARα activation inhibits endothelin-1-induced cardiomyocyte hypertrophy by prevention of NFATc4 binding to GATA-4 Arch. Biochem. Biophys. 518 1 2012 71 78
16. M. Bourajjaj, A.S. Armand, and P.A. da Costa Martins NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure J. Biol. Chem. 283 32 2008 22295 22303
17. E. van Rooij, P.A. Doevendans, and C.C. de Theije Requirement of nuclear factor of activated T-cells in calcineurin-mediated cardiomyocyte hypertrophy J. Biol. Chem. 277 50 2002 48617 48626
18. 2 + channels and transient receptor potential channels activates pathological hypertrophy signaling J. Mol. Cell. Cardiol. 53 5 2012 657 667
19. X. Chen, H. Nakayama, and X. Zhang Calcium influx through Cav1.2 is a proximal signal for pathological cardiomyocyte hypertrophy J. Mol. Cell. Cardiol. 50 3 2011 460 470
20. 2 + channels in neonatal rat cardiomyocytes via the extracellular signal-regulated kinase 1/2 pathway J. Membr. Biol. 246 4 2013 343 353
21. 2 + channel currents in cardiac hypertrophy induced by activation of calcineurin-dependent pathway J. Mol. Cell. Cardiol. 33 2 2001 249 259
22. W. Xing, T.C. Zhang, and D. Cao Myocardin induces cardiomyocyte hypertrophy Circ. Res. 98 8 2006 1089 1097
23. K. Wang, B. Long, and J. Zhou miR-9 and NFATc3 regulate myocardin in cardiac hypertrophy J. Biol. Chem. 285 16 2010 11903 11912
24. 2 + signal-induced cardiomyocyte hypertrophy through activation of myocardin Gene 557 1 2015 43 51
25. X.H. Liao, N. Wang, and Q.X. Liu Myocardin-related transcription factor-a induces cardiomyocyte hypertrophy IUBMB Life 63 1 2011 54 61
26. S. Mushtaq, T. Ali, and Q. Javed N-acetyl cysteine inhibits endothelin-1-induced ROS dependent cardiac hypertrophy through superoxide dismutase regulation Cell J. 17 2 2015 355 360
27. D. Narayanan, Q. Xi, and L.M. Pfeffer Mitochondria control functional CaV1.2 expression in smooth muscle cells of cerebral arteries Circ. Res. 107 5 2010 631 641
28. Y. Wang, S. Tandan, and J.A. Hill Calcineurin-dependent ion channel regulation in heart Trends Cardiovasc. Med. 24 1 2014 14 22
29. R.B. Kleiman, and S.R. Houser Calcium currents in normal and hypertrophied isolated feline ventricular myocytes Am. J. Phys. 255 6 Pt 2 1988 H1434 H1442
30. J. Mészáros, J.J. Coutinho, and S.M. Bryant L-type calcium current in catecholamine-induced cardiac hypertrophy in the rat Exp. Physiol. 82 1 1997 71 83
31. A. Momtaz, A. Coulombe, and P. Richer Action potential and plateau ionic currents in moderately and severely DOCA-salt hypertrophied rat hearts J. Mol. Cell. Cardiol. 28 12 1996 2511 2522
32. A.M. Gómez, H.H. Valdivia, and H. Cheng Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure Science 276 5313 1997 800 806
33. R. Mukherjee, and F.G. Spinale L-type calcium channel abundance and function with cardiac hypertrophy and failure: a review J. Mol. Cell. Cardiol. 30 10 1998 1899 1916
34. T. Aiba, and G.F. Tomaselli Electrical remodeling in the failing heart Curr. Opin. Cardiol. 25 1 2010 29 36
35. + regulation in normal and failing hearts J. Pharmacol. Sci. 100 5 2006 315 322
36. T. Maki, E.J. Gruver, and A.J. Davidoff Regulation of calcium channel expression in neonatal myocytes by catecholamines J. Clin. Invest. 97 3 1996 656 663
37. I.Q. Fan, B. Chen, and J.D. Marsh Transcriptional regulation of L-type calcium channel expression in cardiac myocytes J. Mol. Cell. Cardiol. 32 10 2000 1841 1849
38. K.L. Golden, J. Ren, and A. Dean Norepinephrine regulates the in vivo expression of the L-type calcium channel Mol. Cell. Biochem. 236 1-2 2002 107 114
39. K.L. Golden, J.D. Marsh, and Y. Jiang Castration reduces mRNA levels for calcium regulatory proteins in rat heart Endocrine 19 3 2002 339 344
40. K.L. Golden, J.D. Marsh, and Y. Jiang Testosterone regulates mRNA levels of calcium regulatory proteins in cardiac myocytes Horm. Metab. Res. 36 4 2004 197 202
41. 2 + channels: is membrane depolarization the signal? Circ. Res. 94 10 2004 e97 104
42. A.J. Davidoff, T.M. Maki, and O. Ellingsen Expression of calcium channels in adult cardiac myocytes is regulated by calcium J. Mol. Cell. Cardiol. 29 7 1997 1791 1803
43. H.E. Shubeita, P.M. McDonough, and A.N. Harris Endothelin induction of inositol phospholipid hydrolysis, sarcomere assembly, and cardiac gene expression in ventricular myocytes. A paracrine mechanism for myocardial cell hypertrophy J. Biol. Chem. 265 33 1990 20555 20562
44. J. Oh, Z. Wang, and D.Z. Wang Target gene-specific modulation of myocardin activity by GATA transcription factors Mol. Cell. Biol. 24 19 2004 8519 8528
45. E.E. Creemers, L.B. Sutherland, and J. Oh Coactivation of MEF2 by the SAP domain proteins myocardin and MASTR Mol. Cell 23 1 2006 83 96