Continuous blockade of L-type Ca2+ channels suppresses activation of calcineurin and development of cardiac hypertrophy in spontaneously hypertensive rats

Hypertension Research

Volumn 25, Issue 1, 2002, Pages 117-124

  Zou, Yunzeng ^a   Yamazaki, Tsutomu ^a   Nakagawa, Keiichi ^a   Yamada, Haruyasu ^a   Iriguchi, Norio ^a   Toko, Haruhiro ^a   Takano, Hiroyuki ^a   Akazawa, Hiroshi ^a   Nagai, Ryozo ^a   Komuro, Issei ^a  

^a CHIBA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Ca2+; Calcineurin; Cardiac hypertrophy; Magnetic resonance imaging; Nifedipine

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; CALCINEURIN; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; DRUG VEHICLE; NIFEDIPINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BOLUS INJECTION; CONTINUOUS INFUSION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HEART LEFT VENTRICLE MASS; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART RATE; HEART VENTRICLE HYPERTROPHY; HISTOPATHOLOGY; HYPERTENSION; MALE; NONHUMAN; NORTHERN BLOTTING; NUCLEAR MAGNETIC RESONANCE IMAGING; PHOTOELECTRIC PLETHYSMOGRAPHY; PROTEIN EXPRESSION; RANDOMIZATION; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE;

ANIMALS; ATRIAL NATRIURETIC FACTOR; BLOOD PRESSURE; CALCINEURIN; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CARDIOMEGALY; FIBROSIS; GENE EXPRESSION; HEART RATE; HYPERTENSION; MALE; MYOCARDIUM; NATRIURETIC PEPTIDE, BRAIN; NIFEDIPINE; RATS; RATS, INBRED SHR;

EID: 18244366406     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.25.117     Document Type: Article

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