Possible involvement of endothelin-1 in cardioprotective effects of benidipine

Hypertension Research

Volumn 23, Issue 5, 2000, Pages 491-496

  Ikeda, K ^a   Tojo, K ^a   Tokudome, G ^a   Akashi, T ^a   Hosoya, T ^a   Harada, M ^a   Nakagawa, O ^a   Nakao, K ^a  

^a JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Benidipine; Cardiac hypertrophy; Endothelin 1; Hypertension

Indexed keywords

ANTIBIOTIC AGENT; BENIDIPINE; CALCIUM ANTAGONIST; CALCIUM CHANNEL; ENDOTHELIN 1; HUMORAL ANTIBODY; LEUCINE; NIFEDIPINE; PENICILLIN G; STREPTOMYCIN; THYMIDINE;

ANIMAL CELL; ANTIHYPERTENSIVE THERAPY; ARTICLE; CARDIOVASCULAR DISEASE; CELL SECRETION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; HEART CELL CULTURE; HEART FAILURE; HEART MUSCLE CELL; HEART PROTECTION; HEART VENTRICLE HYPERTROPHY; HYPERTENSION; MOLECULAR INTERACTION; NEWBORN; NONHUMAN; PARACRINE SIGNALING; RAT; VASOCONSTRICTION;

EID: 0033794878     PISSN: 09169636     EISSN: None     Source Type: Journal    
DOI: 10.1291/hypres.23.491     Document Type: Article

References (34)

1. A novel potent vasoconstrictor peptide produced by endothelial cells
2. Recent advances in endothelium research on cardiovascular and endocrine systems
3. Stimulation by corticotropin-releasing factor of atrial natriuretic peptide and brain natriuretic peptide secretions from cultured neonatal rat cardiomyocytes
4. Significance of ventricular myocytes and nonmyocytes interaction during cardiac hypertrophy: Evidence for endothelin-1 as a paracrine hypertrophic factor from cardiac nonmyocytes
5. Urocortin, a newly identified corticotropin-releasing factor-related mammalian peptide, stimulates atrial natriuretic peptide and brain natriuretic peptide secretions from neonatal rat cardiomyocytes
6. Hypertrophic responses of cardiomyocytes induced by endothelin-1 through the protein kinase C-dependent but src and ras-independent pathways
7. ETA receptor antagonist ameliorates nephrosclerosis and left ventricular hypertrophy induced in rat by prolonged inhibition of nitric oxide synthesis
8. Plasma endothelin levels in hypertension and chronic renal failure
9. Increased endothelin in experimental heart failure
10. Plasma endothelin in chronic heart failure
11. Endothelin in human congestive heart failure
12. Prognostic implications of echocardiographically determined left ventricular mass in the Framingham heart study
13. Cardioprotective effects of nilvadipine in hypertensive rats: Attenuation of ET-1 and stimulation of endothelial type nitric oxide synthase mRNA expression
14. Anti-hypertensive effects of a novel dihydropyridine-type Ca antagonist, KW-3049
15. Anti-hypertensive effects of intravenous administration of benidipine hydrochloride and some other calcium and in conscious, spontaneously hypertensive rats
16. Anti-hypertensive effects of the new calcium antagonist benidipine hydrochloride in conscious, renal-hypertensive dogs
17. Hemodynamic effects of benidipine hydrochloride (KW-3049), a new calcium antagonist, in essential hypertension
18. Clinical evaluation of benidipine hydrochloride (KW-3049) in patients with severe hypertension
19. Effects of benidipine hydrochloride on cardiac hypertrophy and coronary flow reserve in renovascular hypertensive rats
20. 2+ concentrations of rat aortic smooth muscle cells induced by insulin
21. The protective effect of benidipine hydrochloride against hypoxic myocardial injury of cultured mouse fetal heart cells
22. Benidipine improves endothelial function in renal resistance arteries of hypertensive rats
23. Effect of benidipine on microvascular remodeling and coronary flow reserve in two-kidney, one clip Goldblatt hypertension
24. Phase I clinical study of benidipine hydrochloride (KW-3049)
25. Age-related changes in the pharmacokinetics and pharmacodynamics of nifedipine
26. Endothelin-1 enhances calcium entry through T-type calcium channels in cultured neonatal rat ventricular myocytes
27. A Ca channel blocker, benidipine, increases coronary blood flow and attenuates the severity of myocardial ischemia via NO-dependent mechanisms in dogs
28. Benidipine stimulates nitric oxide synthetase and improves coronary circulation in hypertensive rats
29. Normalization of left ventricular mass and associated change in neurohormones and atrial natriuretic peptide after 1 year of sustained nifedipine therapy for severe hypertension
30. Relation of regression of left ventricular hypertrophy to changes in ambulatory blood pressure after long-term therapy with perindopril vs. nifedipine
31. Nifedipine in divided doses does not reverse left ventricular hypertrophy in spontaneously hypertensive rats
32. Nifedipine does not impede clenbuterol-stimulated muscle hypertrophy