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Volumn 174, Issue , 2016, Pages 165-170

Both Exocrine Pancreatic Insufficiency and Signs of Pancreatic Inflammation Are Prevalent in Children with Complicated Severe Acute Malnutrition: An Observational Study

Author keywords

amylase; exocrine pancreatic insufficiency; fecal elastase 1; pancreatic inflammation; trypsinogen

Indexed keywords

ALPHA AMYLASE PANCREAS ISOENZYME; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; PANCREATIC ELASTASE; TRYPSINOGEN; AMYLASE;

EID: 84970046442     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2016.04.013     Document Type: Article
Times cited : (26)

References (56)
  • 1
    • 84975904557 scopus 로고    scopus 로고
    • [Internet] United-Nations New York Accessed May 2, 2016
    • United-Nations The Millennium Development Goals Report 2015 [Internet] 2015 United-Nations New York http://www.un.org/millenniumgoals/2015-MDG-Report/pdf/MDG%202015%20rev%20(July%201).pdf Accessed May 2, 2016
    • (2015) The Millennium Development Goals Report 2015
  • 3
    • 41749117073 scopus 로고    scopus 로고
    • Case management of HIV-infected severely malnourished children: Challenges in the area of highest prevalence
    • G.T. Heikens, J. Bunn, B. Amadi, M. Manary, M. Chhagan, J.A. Berkley, and et al. Case management of HIV-infected severely malnourished children: challenges in the area of highest prevalence Lancet 371 2008 1305 1307
    • (2008) Lancet , vol.371 , pp. 1305-1307
    • Heikens, G.T.1    Bunn, J.2    Amadi, B.3    Manary, M.4    Chhagan, M.5    Berkley, J.A.6
  • 4
    • 84926183906 scopus 로고    scopus 로고
    • [Internet] United Nations Children's Fund New York Accessed May 2, 2016
    • UNICEF Levels and trends in child mortality 2015 [Internet] 2015 United Nations Children's Fund New York http://www.childmortality.org/files-v20/download/IGME Report 2015-9-3 LR Web.pdf Accessed May 2, 2016
    • (2015) Levels and Trends in Child Mortality 2015
  • 5
    • 84881182352 scopus 로고    scopus 로고
    • Maternal and child undernutrition and overweight in low-income and middle-income countries
    • R.E. Black, C.G. Victora, S.P. Walker, Z.A. Bhutta, P. Christian, M. de Onis, and et al. Maternal and child undernutrition and overweight in low-income and middle-income countries Lancet 382 2013 427 451
    • (2013) Lancet , vol.382 , pp. 427-451
    • Black, R.E.1    Victora, C.G.2    Walker, S.P.3    Bhutta, Z.A.4    Christian, P.5    De Onis, M.6
  • 7
    • 34247877476 scopus 로고    scopus 로고
    • Treating severe acute malnutrition seriously
    • S. Collins Treating severe acute malnutrition seriously Arch Dis Child 92 2007 453 461
    • (2007) Arch Dis Child , vol.92 , pp. 453-461
    • Collins, S.1
  • 8
    • 0029669908 scopus 로고    scopus 로고
    • Why have mortality rates for severe malnutrition remained so high?
    • C. Schofield, and A. Ashworth Why have mortality rates for severe malnutrition remained so high? Bull World Health Organ 74 1996 223 229
    • (1996) Bull World Health Organ , vol.74 , pp. 223-229
    • Schofield, C.1    Ashworth, A.2
  • 9
    • 80053620967 scopus 로고    scopus 로고
    • Diarrhea is a major killer of children with severe acute malnutrition admitted to inpatient set-up in Lusaka, Zambia
    • A.H. Irena, M. Mwambazi, and V. Mulenga Diarrhea is a major killer of children with severe acute malnutrition admitted to inpatient set-up in Lusaka, Zambia Nutr J 10 2011 110
    • (2011) Nutr J , vol.10 , pp. 110
    • Irena, A.H.1    Mwambazi, M.2    Mulenga, V.3
  • 10
    • 16644369114 scopus 로고    scopus 로고
    • Persistent and chronic diarrhea and malabsorption: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition
    • Z.A. Bhutta, F. Ghishan, K. Lindley, I.A. Memon, S. Mittal, and J.M. Rhoads Persistent and chronic diarrhea and malabsorption: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition J Pediatr Gastroenterol Nutr 39 Suppl 2 2004 S711 S716
    • (2004) J Pediatr Gastroenterol Nutr , vol.39 , pp. S711-S716
    • Bhutta, Z.A.1    Ghishan, F.2    Lindley, K.3    Memon, I.A.4    Mittal, S.5    Rhoads, J.M.6
  • 11
    • 84861875647 scopus 로고    scopus 로고
    • Diarrhoea complicating severe acute malnutrition in Kenyan children: A prospective descriptive study of risk factors and outcome
    • A. Talbert, N. Thuo, J. Karisa, C. Chesaro, E. Ohuma, J. Ignas, and et al. Diarrhoea complicating severe acute malnutrition in Kenyan children: a prospective descriptive study of risk factors and outcome PLoS One 7 2012 e38321
    • (2012) PLoS One , vol.7 , pp. e38321
    • Talbert, A.1    Thuo, N.2    Karisa, J.3    Chesaro, C.4    Ohuma, E.5    Ignas, J.6
  • 13
    • 84873764428 scopus 로고
    • Nutritional oedema
    • P.V. Veghelyi Nutritional oedema Ann Paediatr 175 1950 349 377
    • (1950) Ann Paediatr , vol.175 , pp. 349-377
    • Veghelyi, P.V.1
  • 14
    • 0014312148 scopus 로고
    • The exocrine pancreas and protein-calorie malnutrition
    • G.O. Barbezat, and J.D. Hansen The exocrine pancreas and protein-calorie malnutrition Pediatrics 42 1968 77 92
    • (1968) Pediatrics , vol.42 , pp. 77-92
    • Barbezat, G.O.1    Hansen, J.D.2
  • 15
    • 84960992800 scopus 로고
    • External secretion of the pancreas in chronic infant nutrition disorders
    • [language unknown]
    • N.I. Tarasov External secretion of the pancreas in chronic infant nutrition disorders [language unknown] Vopr Pediatrii 21 1953 33 39
    • (1953) Vopr Pediatrii , vol.21 , pp. 33-39
    • Tarasov, N.I.1
  • 16
    • 0012594546 scopus 로고
    • Pancreatic enzyme activity in duodenal contents of children with a type of kwashiorkor
    • M.D. Thompson, and H.C. Trowell Pancreatic enzyme activity in duodenal contents of children with a type of kwashiorkor Lancet 1 1952 1031 1035
    • (1952) Lancet , vol.1 , pp. 1031-1035
    • Thompson, M.D.1    Trowell, H.C.2
  • 17
    • 0014493102 scopus 로고
    • The pancreas in kwashiorkor. An electron microscopic study
    • W.R. BlackbuRN and K. Vinijchaikul The pancreas in kwashiorkor. An electron microscopic study Lab Invest 20 1969 305 318
    • (1969) Lab Invest , vol.20 , pp. 305-318
    • Blackburn, W.R.1    Vinijchaikul, K.2
  • 18
    • 0014118923 scopus 로고
    • Exocrine pancreatic disease and the malabsorption syndrome in tropical Africa
    • J.G. Banwell, M.R. Hutt, P.J. Leonard, V. Blackman, D.W. Connor, P.D. Marsden, and et al. Exocrine pancreatic disease and the malabsorption syndrome in tropical Africa Gut 8 1967 388 401
    • (1967) Gut , vol.8 , pp. 388-401
    • Banwell, J.G.1    Hutt, M.R.2    Leonard, P.J.3    Blackman, V.4    Connor, D.W.5    Marsden, P.D.6
  • 19
    • 0021999191 scopus 로고
    • Elevated serum immunoreactive pancreatic cationic trypsinogen in acute malnutrition: Evidence of pancreatic damage
    • P.R. Durie, G.G. Forstner, K.J. Gaskin, Z. Weizman, H.R. Kopelman, L. Ellis, and et al. Elevated serum immunoreactive pancreatic cationic trypsinogen in acute malnutrition: evidence of pancreatic damage J Pediatr 106 1985 233 238
    • (1985) J Pediatr , vol.106 , pp. 233-238
    • Durie, P.R.1    Forstner, G.G.2    Gaskin, K.J.3    Weizman, Z.4    Kopelman, H.R.5    Ellis, L.6
  • 20
    • 0005682913 scopus 로고
    • Further observations on the liver pancreas and kidney in malnourished infants and children: The relation of certain histopathological changes in the pancreas and those in liver and kidney
    • G. Bras, J.C. Waterlow, and E. Depass Further observations on the liver pancreas and kidney in malnourished infants and children: the relation of certain histopathological changes in the pancreas and those in liver and kidney West Indian Med J 6 1957 33 42
    • (1957) West Indian Med J , vol.6 , pp. 33-42
    • Bras, G.1    Waterlow, J.C.2    Depass, E.3
  • 21
    • 0026871274 scopus 로고
    • The exocrine pancreas in kwashiorkor and marasmus. Light and electron microscopy
    • S.E. Brooks, and M.H. Golden The exocrine pancreas in kwashiorkor and marasmus. Light and electron microscopy West Indian Med J 41 1992 56 60
    • (1992) West Indian Med J , vol.41 , pp. 56-60
    • Brooks, S.E.1    Golden, M.H.2
  • 22
    • 0022497724 scopus 로고
    • Exocrine pancreatic function of children from the Ivory Coast compared to French children. Effect of kwashiorkor
    • J.F. Sauniere, H. Sarles, Y. Attia, A. Lombardo, T.N. Yoman, R. Laugier, and et al. Exocrine pancreatic function of children from the Ivory Coast compared to French children. Effect of kwashiorkor Dig Dis Sci 31 1986 481 486
    • (1986) Dig Dis Sci , vol.31 , pp. 481-486
    • Sauniere, J.F.1    Sarles, H.2    Attia, Y.3    Lombardo, A.4    Yoman, T.N.5    Laugier, R.6
  • 23
    • 0015596307 scopus 로고
    • Pancreas in primary malnutrition disorders
    • C.S. Pitchumoni Pancreas in primary malnutrition disorders Am J Clin Nutr 26 1973 374 379
    • (1973) Am J Clin Nutr , vol.26 , pp. 374-379
    • Pitchumoni, C.S.1
  • 24
    • 17244377561 scopus 로고    scopus 로고
    • Pancreatic size in protein energy malnutrition: A predictor of nutritional recovery
    • M.A. El-Hodhod, M.F. Nassar, O.A. Hetta, and S.M. Gomaa Pancreatic size in protein energy malnutrition: a predictor of nutritional recovery Eur J Clin Nutr 59 2005 467 473
    • (2005) Eur J Clin Nutr , vol.59 , pp. 467-473
    • El-Hodhod, M.A.1    Nassar, M.F.2    Hetta, O.A.3    Gomaa, S.M.4
  • 26
    • 0032783482 scopus 로고    scopus 로고
    • Cystic fibrosis and the pancreas: Recent scientific advances
    • S. Nousia-Arvanitakis Cystic fibrosis and the pancreas: recent scientific advances J Clin Gastroenterol 29 1999 138 142
    • (1999) J Clin Gastroenterol , vol.29 , pp. 138-142
    • Nousia-Arvanitakis, S.1
  • 27
    • 0000785397 scopus 로고
    • The Syndrome of Pancreatic Insufficiency and Bone Marrow Dysfunction
    • H. Shwachman, L.K. Diamond, F.A. Oski, and K.T. Khaw The Syndrome of Pancreatic Insufficiency and Bone Marrow Dysfunction J Pediatr 65 1964 645 663
    • (1964) J Pediatr , vol.65 , pp. 645-663
    • Shwachman, H.1    Diamond, L.K.2    Oski, F.A.3    Khaw, K.T.4
  • 28
    • 7344251710 scopus 로고    scopus 로고
    • Pancreatic dysfunction and its association with fat malabsorption in HIV infected children
    • A. Carroccio, M. Fontana, M.I. Spagnuolo, G. Zuin, G. Montalto, R.B. Canani, and et al. Pancreatic dysfunction and its association with fat malabsorption in HIV infected children Gut 43 1998 558 563
    • (1998) Gut , vol.43 , pp. 558-563
    • Carroccio, A.1    Fontana, M.2    Spagnuolo, M.I.3    Zuin, G.4    Montalto, G.5    Canani, R.B.6
  • 29
    • 16844383552 scopus 로고    scopus 로고
    • Fecal elastase: Pancreatic status verification and influence on nutritional status in children with cystic fibrosis
    • J.R. Cohen, J.I. Schall, R.F. Ittenbach, B.S. Zemel, and V.A. Stallings Fecal elastase: pancreatic status verification and influence on nutritional status in children with cystic fibrosis J Pediatr Gastroenterol Nutr 40 2005 438 444
    • (2005) J Pediatr Gastroenterol Nutr , vol.40 , pp. 438-444
    • Cohen, J.R.1    Schall, J.I.2    Ittenbach, R.F.3    Zemel, B.S.4    Stallings, V.A.5
  • 31
    • 0015916669 scopus 로고
    • Exocrine pancreatic disease in childhood
    • J.A. Walker-Smith Exocrine pancreatic disease in childhood Med J Aust 1 1973 704 708
    • (1973) Med J Aust , vol.1 , pp. 704-708
    • Walker-Smith, J.A.1
  • 32
    • 0000551632 scopus 로고
    • The essential pathology of kwashiorkor
    • J.N. Davies The essential pathology of kwashiorkor Lancet 1 1948 317 320
    • (1948) Lancet , vol.1 , pp. 317-320
    • Davies, J.N.1
  • 33
    • 77049186715 scopus 로고
    • Clinical aspects of the treatment of kwashiorkor
    • H.C. Trowell Clinical aspects of the treatment of kwashiorkor Ann N Y Acad Sci 57 1954 722 733
    • (1954) Ann N y Acad Sci , vol.57 , pp. 722-733
    • Trowell, H.C.1
  • 34
    • 84937710831 scopus 로고    scopus 로고
    • ESPGHAN and NASPGHAN Report on the Assessment of Exocrine Pancreatic Function and Pancreatitis in Children
    • C.J. Taylor, K. Chen, K. Horvath, D. Hughes, M.E. Lowe, D. Mehta, and et al. ESPGHAN and NASPGHAN Report on the Assessment of Exocrine Pancreatic Function and Pancreatitis in Children J Pediatr Gastroenterol Nutr 61 2015 144 153
    • (2015) J Pediatr Gastroenterol Nutr , vol.61 , pp. 144-153
    • Taylor, C.J.1    Chen, K.2    Horvath, K.3    Hughes, D.4    Lowe, M.E.5    Mehta, D.6
  • 35
    • 0036063628 scopus 로고    scopus 로고
    • How useful is fecal pancreatic elastase 1 as a marker of exocrine pancreatic disease?
    • S. Beharry, L. Ellis, M. Corey, M. Marcon, and P. Durie How useful is fecal pancreatic elastase 1 as a marker of exocrine pancreatic disease? J Pediatr 141 2002 84 90
    • (2002) J Pediatr , vol.141 , pp. 84-90
    • Beharry, S.1    Ellis, L.2    Corey, M.3    Marcon, M.4    Durie, P.5
  • 36
    • 77956825171 scopus 로고    scopus 로고
    • Interpretations: How to use faecal elastase testing
    • N. Nandhakumar, and M.R. Green Interpretations: how to use faecal elastase testing Arch Dis Child Educ Pract Ed 95 2010 119 123
    • (2010) Arch Dis Child Educ Pract Ed , vol.95 , pp. 119-123
    • Nandhakumar, N.1    Green, M.R.2
  • 38
    • 84930586814 scopus 로고    scopus 로고
    • Inconclusive diagnosis of cystic fibrosis after newborn screening
    • C.Y. Ooi, C. Castellani, K. Keenan, J. Avolio, S. Volpi, M. Boland, and et al. Inconclusive diagnosis of cystic fibrosis after newborn screening Pediatrics 135 2015 e1377 e1385
    • (2015) Pediatrics , vol.135 , pp. e1377-e1385
    • Ooi, C.Y.1    Castellani, C.2    Keenan, K.3    Avolio, J.4    Volpi, S.5    Boland, M.6
  • 39
    • 0022980050 scopus 로고
    • Serum immunoreactive cationic trypsinogen: A useful indicator of severe exocrine dysfunction in the paediatric patient without cystic fibrosis
    • D.J. Moore, G.G. Forstner, C. Largman, G.J. CleghoRN S.S. Wong, and P.R. Durie Serum immunoreactive cationic trypsinogen: a useful indicator of severe exocrine dysfunction in the paediatric patient without cystic fibrosis Gut 27 1986 1362 1368
    • (1986) Gut , vol.27 , pp. 1362-1368
    • Moore, D.J.1    Forstner, G.G.2    Largman, C.3    Cleghorn, G.J.4    Wong, S.S.5    Durie, P.R.6
  • 40
    • 27744523426 scopus 로고    scopus 로고
    • Clinical laboratory assessment of acute pancreatitis
    • A.Z. Al-Bahrani, and B.J. Ammori Clinical laboratory assessment of acute pancreatitis Clin Chim Acta 362 2005 26 48
    • (2005) Clin Chim Acta , vol.362 , pp. 26-48
    • Al-Bahrani, A.Z.1    Ammori, B.J.2
  • 41
    • 0036081711 scopus 로고    scopus 로고
    • A critical evaluation of laboratory tests in acute pancreatitis
    • D. Yadav, N. Agarwal, and C.S. Pitchumoni A critical evaluation of laboratory tests in acute pancreatitis Am J Gastroenterol 97 2002 1309 1318
    • (2002) Am J Gastroenterol , vol.97 , pp. 1309-1318
    • Yadav, D.1    Agarwal, N.2    Pitchumoni, C.S.3
  • 43
    • 84888610885 scopus 로고    scopus 로고
    • World Medical Association Declaration of Helsinki: Ethical principles for medical research involving human subjects
    • World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects JAMA 310 2013 2191 2194
    • (2013) JAMA , vol.310 , pp. 2191-2194
  • 45
    • 84879955455 scopus 로고    scopus 로고
    • WHO [Internet]. WHO;. Accessed May 2, 2016
    • WHO. Diarrhoeal disease [Internet]. WHO; http://www.who.int/mediacentre/factsheets/fs330/en/. Accessed May 2, 2016.
    • Diarrhoeal Disease
  • 46
    • 79960081296 scopus 로고    scopus 로고
    • The role of fecal elastase-1 in detecting exocrine pancreatic disease
    • J.S. Leeds, K. Oppong, and D.S. Sanders The role of fecal elastase-1 in detecting exocrine pancreatic disease Nat Rev Gastroenterol Hepatol 8 2011 405 415
    • (2011) Nat Rev Gastroenterol Hepatol , vol.8 , pp. 405-415
    • Leeds, J.S.1    Oppong, K.2    Sanders, D.S.3
  • 47
    • 0029121023 scopus 로고
    • Longitudinal evaluation of serum trypsinogen measurement in pancreatic-insufficient and pancreatic-sufficient patients with cystic fibrosis
    • R.T. Couper, M. Corey, P.R. Durie, G.G. Forstner, and D.J. Moore Longitudinal evaluation of serum trypsinogen measurement in pancreatic-insufficient and pancreatic-sufficient patients with cystic fibrosis J Pediatr 127 1995 408 413
    • (1995) J Pediatr , vol.127 , pp. 408-413
    • Couper, R.T.1    Corey, M.2    Durie, P.R.3    Forstner, G.G.4    Moore, D.J.5
  • 48
    • 0022644083 scopus 로고
    • Age-related alterations of immunoreactive pancreatic cationic trypsinogen in sera from cystic fibrosis patients with and without pancreatic insufficiency
    • P.R. Durie, G.G. Forstner, K.J. Gaskin, D.J. Moore, G.J. CleghoRN S.S. Wong, and et al. Age-related alterations of immunoreactive pancreatic cationic trypsinogen in sera from cystic fibrosis patients with and without pancreatic insufficiency Pediatr Res 20 1986 209 213
    • (1986) Pediatr Res , vol.20 , pp. 209-213
    • Durie, P.R.1    Forstner, G.G.2    Gaskin, K.J.3    Moore, D.J.4    Cleghorn, G.J.5    Wong, S.S.6
  • 50
    • 79952310792 scopus 로고    scopus 로고
    • What have we learned about acute pancreatitis in children?
    • H.X. Bai, M.E. Lowe, and S.Z. Husain What have we learned about acute pancreatitis in children? J Pediatr Gastroenterol Nutr 52 2011 262 270
    • (2011) J Pediatr Gastroenterol Nutr , vol.52 , pp. 262-270
    • Bai, H.X.1    Lowe, M.E.2    Husain, S.Z.3
  • 51
    • 6344248924 scopus 로고    scopus 로고
    • Recurrent acute pancreatitis in anorexia and bulimia
    • L.G. Morris, K.E. Stephenson, S. Herring, and J.L. Marti Recurrent acute pancreatitis in anorexia and bulimia JOP 5 2004 231 234
    • (2004) JOP , vol.5 , pp. 231-234
    • Morris, L.G.1    Stephenson, K.E.2    Herring, S.3    Marti, J.L.4
  • 54
    • 0034101168 scopus 로고    scopus 로고
    • Altered anti-oxidant status and increased lipid peroxidation in marasmic children
    • M.M. Tatli, H. Vural, A. Koc, M. Kosecik, and A. Atas Altered anti-oxidant status and increased lipid peroxidation in marasmic children Pediatr Int 42 2000 289 292
    • (2000) Pediatr Int , vol.42 , pp. 289-292
    • Tatli, M.M.1    Vural, H.2    Koc, A.3    Kosecik, M.4    Atas, A.5
  • 55
    • 84940503291 scopus 로고    scopus 로고
    • Complex reference value distributions and partitioned reference intervals across the pediatric age range for 14 specialized biochemical markers in the CALIPER cohort of healthy community children and adolescents
    • J. Kelly, J.E. Raizman, V. Bevilacqua, M.K. Chan, Y. Chen, F. Quinn, and et al. Complex reference value distributions and partitioned reference intervals across the pediatric age range for 14 specialized biochemical markers in the CALIPER cohort of healthy community children and adolescents Clin Chim Acta 450 2015 196 202
    • (2015) Clin Chim Acta , vol.450 , pp. 196-202
    • Kelly, J.1    Raizman, J.E.2    Bevilacqua, V.3    Chan, M.K.4    Chen, Y.5    Quinn, F.6
  • 56
    • 84905125443 scopus 로고    scopus 로고
    • Diagnosing acute pancreatitis in children: What is the diagnostic yield and concordance for serum pancreatic enzymes and imaging within 96 h of presentation?
    • M.J. Coffey, S. Nightingale, and C.Y. Ooi Diagnosing acute pancreatitis in children: what is the diagnostic yield and concordance for serum pancreatic enzymes and imaging within 96 h of presentation? Pancreatology 14 2014 251 256
    • (2014) Pancreatology , vol.14 , pp. 251-256
    • Coffey, M.J.1    Nightingale, S.2    Ooi, C.Y.3


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