Transient biocompatible polymeric platforms for long-term controlled release of therapeutic proteins and vaccines

Materials

Volumn 9, Issue 5, 2016, Pages

  Acar, Handan ^a   Banerjee, Saikat ^b   Shi, Heliang ^b   Jamshidi, Reihaneh ^a,b   Hashemi, Nastaran ^a,b,c   Cho, Michael W ^b   Montazami, Reza ^a,b,c  

^a Iowa State University   (United States)

^b IOWA STATE UNIVERSITY   (United States)

^c IOWA STATE UNIVERSITY   (United States)

Author keywords

Controlled release; Long term release; Polymer platform; Transient platform

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADABLE POLYMERS; BIOLOGICAL MATERIALS; CYTOTOXICITY; FUNCTIONAL POLYMERS; INTERPENETRATING POLYMER NETWORKS; KINETICS; VACCINES;

CELL VIABILITY ASSAYS; CONTROLLED RELEASE; LONG-TERM RELEASE; POLYMER PLATFORM; PREPARATION METHOD; RELEASE ANALYSIS; RELEASE KINETICS; THERAPEUTIC PROTEIN;

PROTEINS;

EID: 84969932249     PISSN: None     EISSN: 19961944     Source Type: Journal    
DOI: 10.3390/ma9050321     Document Type: Article

References (58)

1. Liu, S.; Montazami, R.; Liu, Y.; Jain, V.; Lin, M.; Heflin, J.R.; Zhang, Q.M. Layer-by-layer self-assembled conductor network composites in ionic polymer metal composite actuators with high strain response. Appl. Phys. Lett. 2009, 95.
2. Liu, S.; Montazami, R.; Liu, Y.; Jain, V.; Lin, M.; Zhou, X.; Heflin, J.R.; Zhang, Q.M. Influence of the conductor network composites on the electromechanical performance of ionic polymer conductor network composite actuators. Sens. Actuators A Phys. 2010, 157, 267-275.
3. Liu, Y.; Liu, S.; Lin, J.; Wang, D.; Jain, V.; Montazami, R.; Heflin, J.R.; Li, J.; Madsen, L.; Zhang, Q.M. Ion transport and storage of ionic liquids in ionic polymer conductor network composites. Appl. Phys. Lett. 2010
4. Liu, Y.; Zhao, R.; Ghaffari, M.; Lin, J.; Liu, S.; Cebeci, H.; de Villoria, R.G.; Montazami, R.; Wang, D.; Wardle, B.L.; et al. Equivalent circuit modeling of ionomer and ionic polymer conductive network composite actuators containing ionic liquids. Sens. Actuators A Phys. 2012, 181, 70-76.
5. Meis, C.; Hashemi, N.; Montazami, R. Investigation of spray-coated silver-microparticle electrodes for ionic electroactive polymer actuators. J. Appl. Phys. 2014, 115.
6. Montazami, R.; Liu, S.; Liu, Y.; Wang, D.; Zhang, Q.; Heflin, J.R. Thickness dependence of curvature, strain, and response time in ionic electroactive polymer actuators fabricated via layer-by-layer assembly. J. Appl. Phys. 2011, 109.
7. Montazami, R.; Wang, D.; Heflin, J.R. Influence of conductive network composite structure on the electromechanical performance of ionic electroactive polymer actuators. Int. J. Smart Nano Mater. 2012, 3, 204-213.
8. Tsai, H.K.A.; Moschou, E.A.; Daunert, S.; Madou, M.; Kulinsky, L. Integrating biosensors and drug delivery: A step closer toward scalable responsive drug-delivery systems. Adv. Mater. 2009, 21, 656-660.
9. Schmidt, D.J.; Moskowitz, J.S.; Hammond, P.T. Electrically triggered release of a small molecule drug from a polyelectrolyte multilayer coating. Chem. Mater. 2010, 22, 6416-6425.
10. Bubnova, O.; Khan, Z.U.;Wang, H.; Braun, S.; Evans, D.R.; Fabretto, M.; Hojati-Talemi, P.; Dagnelund, D.; Arlin, J.-B.; Geerts, Y.H.; et al. Semi-metallic polymers. Nat. Mater. 2014, 13.
11. Giusti, P.; Lazzeri, L.; de Petris, S.; Palla, M.; Cascone, M.G. Collagen-based new bioartificial polymeric materials. Biomaterials 1994, 15, 1229-1233.
12. Hsieh, T.-T.; Hsieh, K.-H.; Simon, G.P.; Tiu, C. Interpenetrating polymer networks of 2-hydroxyethyl methacrylate terminated polyurethanes and polyurethanes. Polymer 1999, 40, 3153-3163.
13. Kosmala, J.D.; Henthorn, D.B.; Brannon-Peppas, L. Preparation of interpenetrating networks of gelatin and dextran as degradable biomaterials. Biomaterials 2000, 21, 2019-2023.
14. Changez, M.; Burugapalli, K.; Koul, V.; Choudhary, V. The effect of composition of poly(acrylic acid)-gelatin hydrogel on gentamicin sulphate release: In vitro. Biomaterials 2003, 24, 527-536.
15. Rivnay, J.; Owens, R.M.; Malliaras, G.G. The Rise of organic bioelectronics. Chem. Mater. 2014, 26, 679-685.
16. Dong, Z.; Wang, Q.; Du, Y. Alginate/gelatin blend films and their properties for drug controlled release. J. Membr. Sci. 2006, 280, 37-44.
17. Bergo, P.; Moraes, I.; Sobral, P. Effects of plasticizer concentration and type on moisture content in gelatin films. Food Hydrocoll. 2013, 32, 412-415.
18. Dhawale, D.S.; Mane, G.P.; Joseph, S.; Anand, C.; Ariga, K.; Vinu, A. Enhanced supercapacitor performance of N-doped mesoporous carbons prepared from a gelatin biomolecule. ChemPhysChem 2013, 14, 1563-1569.
19. Cortesi, R.; Nastruzzi, C.; Davis, S.S. Sugar cross-linked gelatin for controlled release: Microspheres and disks. Biomaterials 1998, 19, 1641-1649.
20. Kanmani, P.; Rhim, J.-W. Physical, mechanical and antimicrobial properties of gelatin based active nanocomposite films containing AgNPs and nanoclay. Food Hydrocoll. 2014, 35, 644-652.
21. Tabata, Y.; Ikada, Y. Protein release from gelatin matrices. Adv. Drug Deliv. Rev. 1998, 31, 287-301.
22. Tabata, Y.; Nagano, A.; Ikada, Y. Biodegradation of hydrogel carrier incorporating fibroblast growth factor. Tissue Eng. 1999, 5, 127-138.
23. Sinha, V.R.; Trehan, A. Biodegradable microspheres for protein delivery. J. Control. Release 2003, 90, 261-280.
24. Ulubayram, K.; Cakar, A.N.; Korkusuz, P.; Ertan, C.; Hasirci, N. EGF containing gelatin-based wound dressings. Biomaterials 2001, 22, 1345-1356.
25. Liu, Y.; Chan-Park, M.B. Hydrogel based on interpenetrating polymer networks of dextran and gelatin for vascular tissue engineering. Biomaterials 2009, 30, 196-207.
26. Peng, S.; Niu, L.H.; Lai, K.Q.; Huang, Y.Q. Physicochemical properties of biodegradable Tilapia skin gelatin film and gelatin-polysaccharide based composite films. Adv. Mater. Res. 2014, 941.
27. Ponez, L.; Sentanin, F.; Majid, S.; Arof, A.; Pawlicka, A. Ion-conducting membranes based on gelatin and containing LiI/I2 for electrochromic devices. Mol. Cryst. Liquid Cryst. 2012, 554, 239-251.
28. Bui, A.; Virgilio, N. Tuning organogel properties by controlling the organic-phase composition. Ind. Eng. Chem. Res. 2013, 52, 14185-14191.
29. Jamshidi, R.; Çinar, S.; Chen, Y.; Hashemi, N.; Montazami, R. Transient bioelectronics: Electronic properties of silver microparticle-based circuits on polymeric substrates subjected to mechanical load. J. Polym. Sci. Part B Polym. Phys. 2015, 53, 1603-1610.
30. Caplin, J.D.; Granados, N.G.; James, M.R.; Montazami, R.; Hashemi, N. Microfluidic Organ-on-a-chip technology for advancement of drug development and toxicology. Adv. Healthc. Mater. 2015, 4, 1426-1450.
31. Eldridge, J.E.; Ferry, J.D. Studies of the cross-linking process in gelatin gels. III. Dependence of melting point on concentration and molecular weight. J. Phys. Chem. 1954, 58, 992-995.
32. Kuijpers, A.J.; Engbers, G.H.M.; Krijgsveld, J.; Zaat, S.A.J.; Dankert, J.; Feijen, J. Cross-linking and characterisation of gelatin matrices for biomedical applications. J. Biomater. Sci. Polym. Ed. 2000, 11, 225-243.
33. Liu, Y.; An, M.; Wang, L.; Qiu, H. Preparation and characterization of chitosan-gelatin/glutaraldehyde scaffolds. J. Macromol. Sci. Part B 2014, 53.
34. Khan, S.; Ranjha, N. Effect of degree of cross-linking on swelling and on drug release of low viscous chitosan/poly(vinyl alcohol) hydrogels. Polym. Bull. 2014, 71, 2133-2158.
35. Martinez, A.W.; Caves, J.M.; Ravi, S.; Li, W.; Chaikof, E.L. Effects of crosslinking on the mechanical properties, drug release and cytocompatibility of protein polymers. Acta Biomater. 2014, 10, 26-33.
36. Bigi, A.; Panzavolta, S.; Rubini, K. Relationship between triple-helix content and mechanical properties of gelatin films. Biomaterials 2004, 25, 5675-5680.
37. Hago, E.-E.; Li, X. Interpenetrating polymer network hydrogels based on gelatin and PVA by biocompatible approaches: Synthesis and characterization. Adv. Mater. Sci. Eng. 2013, 2013.
38. Acar, H.; Çinar, S.; Thunga, M.; Kessler, M.R.; Hashemi, N.; Montazami, R. Study of physically transient insulating materials as a potential platform for transient electronics and bioelectronics. Adv. Funct. Mater. 2014, 24, 4135-4143.
39. Frey, G.; Chen, J.; Rits-Volloch, S.; Freeman, M.M.; Zolla-Pazner, S.; Chen, B. Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies. Nat. Struct. Mol. Biol. 2010, 17, 1486-1491.
40. Naftalin, R.J.; Symons, M.C.R. The mechanism of sugar-dependent stabilisation of gelatin gels. Biochim. Biophys. Acta (BBA) Biomembr. 1974, 352, 173-178.
41. Cuq, B.; Gontard, N.; Cuq, J.-L.; Guilbert, S. Selected functional properties of fish myofibrillar protein-based films as affected by hydrophilic plasticizers. J. Agric. Food Chem. 1997, 45, 622-626.
42. Thomazine, M.; Carvalho, R.A.; Sobral, P.J.A. Physical properties of gelatin films plasticized by blends of glycerol and sorbitol. J. Food Sci. 2005, 70, E172-E176.
43. Tanaka, M.; Iwata, K.; Sanguandeekul, R.; Handa, A.; Ishizaki, S. Influence of plasticizers on the properties of edible films prepared from fish water-soluble proteins. Fish. Sci. 2001, 67, 346-351.
44. Krogars, K.; Heinämäki, J.; Karjalainen, M.; Niskanen, A.; Leskelä, M.; Yliruusi, J. Enhanced stability of rubbery amylose-rich maize starch films plasticized with a combination of sorbitol and glycerol. Int. J. Pharm. 2003, 251, 205-208.
45. Cherian, G.; Gennadios, A.;Weller, C.L.; Chinachoti, P. Thermomechanical behavior of wheat gluten films: Effect of sucrose, glycerin, and sorbitol. Cereal Chem. 1995, 72, 1-6.
46. Miller, E.J.; Oldinski, R.A. Poly (vinyl alcohol)-gelatin interpenetrating network hydrogels for tissue engineering applications. In Proceedings of the 2014 40th AnnualNortheast Bioengineering Conference (NEBEC), Boston, MA, USA, 25-27 April 2014.
47. Daniele, M.A.; Adams, A.A.; Naciri, J.; North, S.H.; Ligler, F.S. Interpenetrating networks based on gelatin methacrylamide and PEG formed using concurrent thiol click chemistries for hydrogel tissue engineering scaffolds. Biomaterials 2014, 35, 1845-1856.
48. Aminabhavi, T.M.; Nadagouda, M.N.; More, U.A.; Joshi, S.D.; Kulkarni, V.H.; Noolvi, M.N.; Kulkarni, P.V. Controlled release of therapeutics using interpenetrating polymeric networks. Expert Opin. Drug Deliv. 2015, 12, 669-688.
49. Qin, Y.; Banasik, M.; Kim, S.; Penn-Nicholson, A.; Habte, H.H.; LaBranche, C.; Montefiori, D.C.;Wang, C.; Cho, M.W. Eliciting neutralizing antibodies with gp120 outer domain constructs based on M-group consensus sequence. Virology 2014, 462-463, 363-376.
50. Rokhade, A.P.; Agnihotri, S.A.; Patil, S.A.; Mallikarjuna, N.N.; Kulkarni, P.V.; Aminabhavi, T.M. Semi-interpenetrating polymer network microspheres of gelatin and sodium carboxymethyl cellulose for controlled release of ketorolac tromethamine. Carbohydr. Polym. 2006, 65, 243-252.
51. Wang, Y.; Bansal, V.; Zelikin, A.N.; Caruso, F. Templated synthesis of single-component polymer capsules and their application in drug delivery. Nano Lett. 2008, 8, 1741-1745.
52. Elzoghby, A.O.; Samy, W.M.; Elgindy, N.A. Protein-based nanocarriers as promising drug and gene delivery systems. J. Control. Release 2012, 161, 38-49.
53. Narasimhan, B. Mathematical models describing polymer dissolution: Consequences for drug delivery. Adv. Drug Deliv. Rev. 2001, 48, 195-210.
54. Shen, E.; Kipper, M.J.; Dziadul, B.; Lim, M.-K.; Narasimhan, B. Mechanistic relationships between polymer microstructure and drug release kinetics in bioerodible polyanhydrides. J. Control. Release 2002, 82, 115-125.
55. Speer, D.P.; Chvapil, M.; Eskelson, C.; Ulreich, J. Biological effects of residual glutaraldehyde in glutaraldehyde-tanned collagen biomaterials. J. Biomed. Mater. Res. 1980, 14, 753-764.
56. Sanders, L.M.; McRae, G.I.; Vitale, K.M.; Kell, B.A. Controlled delivery of an LHRH analogue from biodegradable injectable microspheres. J. Control. Release 1985, 2, 187-195.
57. Jiang, S.; Lin, K.; Lu, M. A conformation-specific monoclonal antibody reacting with fusion-active gp41 from the human immunodeficiency virus type 1 envelope glycoprotein. J. Virol. 1998, 72, 10213-10217.
58. Attarwala, H.; Amiji, M. Multi-compartmental nanoparticles-in-emulsion formulation for macrophage-specific anti-inflammatory gene delivery. Pharm. Res. 2012, 29, 1637-1649.