Effects of crosslinking on the mechanical properties, drug release and cytocompatibility of protein polymers

Acta Biomaterialia

Volumn 10, Issue 1, 2014, Pages 26-33

  Martinez, Adam W ^a   Caves, Jeffrey M ^b   Ravi, Swathi ^a   Li, Wehnsheng ^a   Chaikof, Elliot L ^a,b,c  

^a Emory University   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

Crosslinking; Drug release; Mechanical properties; Protein polymer

Indexed keywords

BIOMEDICAL EQUIPMENT; CONTROLLED DRUG DELIVERY; ELASTIN; FUNCTIONAL POLYMERS; POLYMER FILMS; RECOMBINANT PROTEINS; SULFUR COMPOUNDS; TARGETED DRUG DELIVERY; TENSILE STRENGTH;

COMPONENT MATERIALS; CYTOCOMPATIBILITY; DRUG RELEASE; ELASTIN-LIKE PROTEINS; PROCESSING STRATEGIES; PROTEIN POLYMERS; ULTIMATE TENSILE STRENGTH; VAPOR PHASE; VAPOR PHASIS; VAPOUR-PHASE;

CROSSLINKING;

DISULFIDE; GENIPIN; GLUTARALDEHYDE; POLYMER; PROTEIN; PROTEIN POLYMER; UNCLASSIFIED DRUG;

ARTICLE; BIOCOMPATIBILITY; CELL ADHESION; CELL PROLIFERATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG RELEASE; ELUTION; FILM; GEL; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN PROCESSING; RIGIDITY; STRESS STRAIN RELATIONSHIP; TENSILE STRENGTH; UMBILICAL VEIN ENDOTHELIAL CELL; VAPOR; WATER CONTENT;

CROSSLINKING; DRUG RELEASE; MECHANICAL PROPERTIES; PROTEIN POLYMER;

CROSS-LINKING REAGENTS; DISULFIDES; DRUG DELIVERY SYSTEMS; ELASTIN; FIBRONECTINS; GLUTARAL; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; IRIDOIDS; MECHANICAL PHENOMENA; SIROLIMUS; WATER;

EID: 84888641382     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.08.029     Document Type: Article

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