The protective role of Nrf2-Gadd45b against antimony-induced oxidative stress and apoptosis in HEK293 cells

Toxicology Letters

Volumn 256, Issue , 2016, Pages 11-18

  Jiang, Xingkang ^a   An, Zesheng ^a   Lu, Chao ^a   Chen, Yue ^a   Du, E ^a   Qi, Shiyong ^a   Yang, Kuo ^a   Zhang, Zhihong ^a   Xu, Yong ^a  

^a SECOND HOSPITAL OF TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Antimony; Apoptosis; Gadd45b; Nrf2; ROS

Indexed keywords

ACETYLCYSTEINE; ANTIMONY DERIVATIVE; ANTIMONY TRIOXIDE; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTIMONY; DIFFERENTIATION ANTIGEN; GADD45B PROTEIN, HUMAN; NFE2L2 PROTEIN, HUMAN;

ANTIOXIDANT RESPONSIVE ELEMENT; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CORRELATIONAL STUDY; CYTOTOXICITY; HEK293 CELL LINE; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; BINDING SITE; DOSE RESPONSE; DRUG EFFECTS; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; KIDNEY; METABOLISM; PATHOLOGY; PHOSPHORYLATION; REPORTER GENE; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ANTIGENS, DIFFERENTIATION; ANTIMONY; APOPTOSIS; BINDING SITES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENES, REPORTER; HEK293 CELLS; HUMANS; KIDNEY; MITOGEN-ACTIVATED PROTEIN KINASES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; REACTIVE OXYGEN SPECIES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 84969528836     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2016.05.016     Document Type: Article

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