Hepatic oxidative stress activates the Gadd45b gene by way of degradation of the transcriptional repressor STAT3

Hepatology

Volumn 59, Issue 2, 2014, Pages 695-704

  Kim, Jung Hwan ^a   Qu, Aijuan ^a   Reddy, Janardan K ^b   Gao, Bin ^c   Gonzalez, Frank J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACOX1 ENZYME; ENZYME; FATTY ACID; HYDROGEN PEROXIDE; MESSENGER RNA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PIRINIXIC ACID; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONTROLLED STUDY; FATTY ACID OXIDATION; GENE; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE INDUCTION; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45BETA GENE; LIVER; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; UBIQUITINATION; WILD TYPE;

ANIMALS; ANTIGENS, DIFFERENTIATION; CELLS, CULTURED; HEPATOCYTES; HYDROGEN PEROXIDE; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, ANIMAL; OXIDATIVE STRESS; PEROXISOME PROLIFERATORS; PPAR ALPHA; PYRIMIDINES; RNA, MESSENGER; STAT3 TRANSCRIPTION FACTOR;

EID: 84893637033     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.26683     Document Type: Article

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