The etiology of Ebola virus disease-like illnesses in Ebola virusnegative patients from Sierra Leone

Oncotarget

Volumn 7, Issue 19, 2016, Pages 27910-27915

  Li, Wen Gang ^a   Chen, Wei Wei ^a,b   Li, Lei ^a,b   Ji, Dong ^a,b   Ji, Ying Jie ^a,b   Li, Chen ^a,b   Gao, Xu Dong ^a,b   Wang, Li Fu ^a,b   Zhao, Min ^a,b   Duan, Xue Zhang ^a,b   Duan, Hui Juan ^a,b  

^a 302 Military Hospital of Chinese PLA   (China)

^b Sierra Leone China Friendship Hospital   (Sierra Leone)

Author keywords

Ebola virus disease (EVD); EVD suspected cases; HIV; Lassa fever; Malaria

Indexed keywords

AGED; ARTHRALGIA; ARTICLE; BLEEDING; CHILD; CLINICAL FEATURE; COMPARATIVE STUDY; CONTROLLED STUDY; DIARRHEA; DISEASE ASSOCIATION; EBOLA VIRUS DISEASE LIKE ILLNESS; EBOLA VIRUS NEGATIVE PATIENT; FATIGUE; FEMALE; FEVER; HEADACHE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LASSA FEVER; MAJOR CLINICAL STUDY; MALARIA; MALE; NAUSEA; PATIENT; PHYSICAL DISEASE; PNEUMONIA; REAL TIME POLYMERASE CHAIN REACTION; SIERRA LEONE; TUBERCULOSIS; VOMITING; YELLOW FEVER; ADOLESCENT; ADULT; EBOLA HEMORRHAGIC FEVER; EBOLAVIRUS; EPIDEMIC; HUMAN IMMUNODEFICIENCY VIRUS; ISOLATION AND PURIFICATION; LASSA VIRUS; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PLASMODIUM MALARIAE; PRESCHOOL CHILD; VERY ELDERLY; VIROLOGY; YELLOW FEVER VIRUS; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ARTHRALGIA; CHILD; CHILD, PRESCHOOL; DIARRHEA; DISEASE OUTBREAKS; EBOLAVIRUS; FATIGUE; FEMALE; FEVER; HEADACHE; HEMORRHAGE; HEMORRHAGIC FEVER, EBOLA; HIV; HUMANS; LASSA VIRUS; MALE; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; NAUSEA; PLASMODIUM MALARIAE; REAL-TIME POLYMERASE CHAIN REACTION; SIERRA LEONE; VOMITING; YELLOW FEVER VIRUS; YOUNG ADULT;

EID: 84968909195     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.8558     Document Type: Article

References (23)

1. Gire SK, Goba A, Andersen KG, Sealfon RS, Park DJ, Kanneh L, Jalloh S, Momoh M, Fullah M, Dudas G, Wohl S, Moses LM, Yozwiak NL, et al. Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science. 2014; 345:1369-1372.
2. Kuhn JH, Dodd LE, Wahl-Jensen V, Radoshitzky SR, Bavari S, Jahrling PB. Evaluation of perceived threat differences posed by filovirus variants. Biosecur Bioterro. 2011; 9:361-371.
3. Yan T, Mu J, Qin E, Wang Y, Liu L, Wu D, Jia H, Li Z, Guo T, Wang X, Qin Y, Li Y, Chen S, et al. Clinical characteristics of 154 patients suspected of having Ebola virus disease in the Ebola holding center of Jui Government Hospital in Sierra Leone during the 2014 Ebola outbreak. Eur J Clin Microbiol Infect Dis. 2015; 34:2089-2095.
4. Lu Y, Rong G, Yu SP, Sun Z, Duan X, Dong Z, Xia H, Zhan N, Jin C, Ji J, Duan H. Chinese military medical teams in the Ebola outbreak of Sierra Leone. J R Army Med Corps. 2016. pii: jramc-2015-000562.
5. Pinsky BA, Sahoo MK, Sandlund J, Kleman M, Kulkarni M, Grufman P, Nygren M, Kwiatkowski R, Baron EJ, Tenover F, Denison B, Higuchi R, Van Atta R, et al. Analytical Performance Characteristics of the Cepheid GeneXpert Ebola Assay for the Detection of Ebola Virus. PloS one. 2015; 10:e0142216.
6. Lado M, Walker NF, Baker P, Haroon S, Brown CS, Youkee D, Studd N, Kessete Q, Maini R, Boyles T, Hanciles E, Wurie A, Kamara TB, et al. Clinical features of patients isolated for suspected Ebola virus disease at Connaught Hospital, Freetown, Sierra Leone: a retrospective cohort study. Lancet Infect Dis. 2015; 15:1024-1033.
7. Schieffelin JS, Shaffer JG, Goba A, Gbakie M, Gire SK, Colubri A, Sealfon RS, Kanneh L, Moigboi A, Momoh M, Fullah M, Moses LM, Brown BL, et al. Clinical illness and outcomes in patients with Ebola in Sierra Leone. N Engl J Med. 2014; 371:2092-2100.
8. Case Definition for Ebola Virus Disease (EVD). Available at: http://www.cdc.gov/vhf/ebola/healthcare-us/evaluatingpatients/case-definition.html.
9. Dedkov VG, Magassouba NF, Safonova MV, Deviatkin AA, Dolgova AS, Pyankov OV, Sergeev AA, Utkin DV, Odinokov GN, Safronov VA, Agafonov AP, Maleev VV, Shipulin GA. Development and evaluation of a real-time RT-PCR assay for the detection of Ebola virus (Zaire) during an Ebola outbreak in Guinea in 2014-2015. J Virol Methods. 2015; 228:26-30.
10. Mattiuzzo G, Ashall J, Doris KS, MacLellan-Gibson K, Nicolson C, Wilkinson DE, Harvey R, Almond N, Anderson R, Efstathiou S, Minor PD, Page M. Development of Lentivirus-Based Reference Materials for Ebola Virus Nucleic Acid Amplification Technology-Based Assays. PloS one. 2015; 10:e0142751.
11. Nouvellet P, Garske T, Mills HL, Nedjati-Gilani G, Hinsley W, Blake IM, Van Kerkhove MD, Cori A, Dorigatti I, Jombart T, Riley S, Fraser C, Donnelly CA, et al. The role of rapid diagnostics in managing Ebola epidemics. Nature. 2015; 528:S109-116.
12. Simon GG. Impacts of Neglected Tropical Disease on Incidence and Progression of HIV/AIDS, Tuberculosis and Malaria: Scientific Links. Int J Infect Dis. 2015; 373:2448-54.
13. Havelaar AH, Kirk MD, Torgerson PR, Gibb HJ, Hald T, Lake RJ, Praet N, Bellinger DC, de Silva NR, Gargouri N, Speybroeck N, Cawthorne A, Mathers C, et al. World Health Organization Global Estimates and Regional Comparisons of the Burden of Foodborne Disease in 2010. PLoS Med. 2015; 12:e1001923.
14. Muhlberger N, Jelinek T, Gascon J, Probst M, Zoller T, Schunk M, Beran J, Gjorup I, Behrens RH, Clerinx J, Bjorkman A, McWhinney P, Matteelli A, et al. Epidemiology and clinical features of vivax malaria imported to Europe: sentinel surveillance data from TropNetEurop. Malar J. 2004; 3:5.
15. Bah EI, Lamah MC, Fletcher T, Jacob ST, Brett-Major DM, Sall AA, Shindo N, Fischer WA 2nd, Lamontagne F, Saliou SM, Bausch DG, Moumie B, Jagatic T, et al. Clinical presentation of patients with Ebola virus disease in Conakry, Guinea. N Engl J Med. 2015; 372:40-47.
16. Qin E, Bi J, Zhao M, Wang Y, Guo T, Yan T, Li Z, Sun J, Zhang J, Chen S, Wu Y, Li J, Zhong Y. Clinical Features of Patients With Ebola Virus Disease in Sierra Leone. Clin Infect Dis. 2015; 61:491-495.
17. Gao X, Rong G, Lu Y, Duan X, Duan H. Symptoms closely associated with Ebola virus disease. Lancet Infect Dis. 2016; 16:18-19.
18. Li Y, Zhao JK, Wang M, Han ZG, Cai WP, Zheng BJ, Xu HF. Current antibody-based immunoassay algorithm failed to confirm three late-stage AIDS cases in China: case report. Virol J. 2010; 7:58.
19. Centers for Disease C, Prevention. National HIV Testing Day and new testing recommendations. MMWR Morb Mortal Wkly Rep. 2014; 63:537.
20. Mate SE, Kugelman JR, Nyenswah TG, Ladner JT, Wiley MR, Cordier-Lassalle T, Christie A, Schroth GP, Gross SM, Davies-Wayne GJ, Shinde SA, Murugan R, Sieh SB, et al. Molecular Evidence of Sexual Transmission of Ebola Virus. N Engl J Med. 2015.
21. Edwards JK, Kleine C, Munster V, Giuliani R, Massaquoi M, Sprecher A, Chertow DS. Interpretation of Negative Molecular Test Results in Patients With Suspected or Confirmed Ebola Virus Disease: Report of Two Cases. Open Forum Infect Dis. 2015; 2:ofv137.
22. Sarin SK, Kumar A, Almeida JA, Chawla YK, Fan ST, Garg H, de Silva HJ, Hamid SS, Jalan R, Komolmit P, Lau GK, Liu Q, Madan K, et al. Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL). Hepatology international. 2009; 3:269-282.
23. Lu HJ, Qian J, Kargbo D, Zhang XG, Yang F, Hu Y, Sun Y, Cao YX, Deng YQ, Su HX, Dafae F, Sun Y, Wang CY, et al. Ebola Virus Outbreak Investigation, Sierra Leone, September 28-November 11, 2014. Emerging infectious diseases. 2015; 21:1921-1927.