Enhanced GABA Transmission Drives Bradykinesia Following Loss of Dopamine D2 Receptor Signaling

Neuron

Volumn 90, Issue 4, 2016, Pages 824-838

  Lemos, Julia C ^a   Friend, Danielle M ^b   Kaplan, Alanna R ^a   Shin, Jung Hoon ^a   Rubinstein, Marcelo ^d,e,f   Kravitz, Alexxai V ^b,c   Alvarez, Veronica A ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^d INSTITUTO DE INVESTIGACIONES EN INGENIERÍA GENÉTICA Y BIOLOGÍA MOLECULAR   (Argentina)

^e UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^f UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOPAMINE 2 RECEPTOR; 4 AMINOBUTYRIC ACID; DOPAMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRADYKINESIA; BRAIN NERVE CELL; CONTROLLED STUDY; CORPUS STRIATUM; DEPLETION; DOPAMINERGIC TRANSMISSION; GABAERGIC TRANSMISSION; GENE DELETION; GLOBUS PALLIDUS; IN VIVO STUDY; INDIRECT PATHWAY MEDIUM SPINY NEURON; LOCOMOTION; MOUSE; MOUSE MODEL; NERVE CELL; NERVE CELL MEMBRANE POTENTIAL; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; HYPOKINESIA; METABOLISM; PHYSIOLOGY; SUBSTANTIA NIGRA; TRANSGENIC MOUSE;

ANIMALS; CORPUS STRIATUM; DOPAMINE; GAMMA-AMINOBUTYRIC ACID; GLOBUS PALLIDUS; HYPOKINESIA; MICE, TRANSGENIC; NEURONS; PARKINSON DISEASE; RECEPTORS, DOPAMINE D2; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA;

EID: 84968854650     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2016.04.040     Document Type: Article

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