Analysis of the fungal microbiome in exhaled breath condensate of patients with asthma

Allergy and Asthma Proceedings

Volumn 37, Issue 3, 2016, Pages e41-e46

  Carpagnano, Giovanna E ^a   Malerba, Mario ^b   Lacedonia, Donato ^a   Susca, Antonia ^c   Logrieco, Antonio ^c   Carone, Mauro ^d   Cotugno, Grazia ^a   Palmiotti, Giuseppe A ^a   Foschino Barbaro, Maria P ^a  

^a UNIVERSITY OF FOGGIA   (Italy)

^b UNIVERSITY OF BRESCIA   (Italy)

^c INSTITUTE OF SCIENCES OF FOOD PRODUCTION   (Italy)

^d IRCCS   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AGAR;

ADULT; ALLERGIC ASTHMA; ANTHROPOMETRIC PARAMETERS; ARTICLE; ASTHMA; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE CONTROL; DISEASE SEVERITY; EXHALATION; EXHALED BREATH CONDENSATE; FEMALE; FUNGAL COLONIZATION; FUNGAL DETECTION; FUNGUS; FUNGUS CULTURE; HUMAN; HUMAN CELL; MALE; MICROBIOME; NONHUMAN; OBESITY; RESPIRATORY TRACT PARAMETERS; SPUTUM EXAMINATION; YEAST; BREATH ANALYSIS; CASE CONTROL STUDY; COHORT ANALYSIS; MICROBIOLOGY; MYCOBIOME; PROCEDURES; SEVERITY OF ILLNESS INDEX; SPUTUM;

ASTHMA; BREATH TESTS; CASE-CONTROL STUDIES; COHORT STUDIES; HUMANS; MYCOBIOME; OBESITY; SEVERITY OF ILLNESS INDEX; SPUTUM;

EID: 84968611454     PISSN: 10885412     EISSN: 15396304     Source Type: Journal    
DOI: 10.2500/aap.2016.37.3943     Document Type: Article

References (35)

1. FitzGerald JM, Bateman ED, Boulet LP, et al. Global strategy for asthma management and prevention, Global Initiative for Asthma (GINA) 2015. Available online at http://www.ginasthma.org/; accessed.
2. Gern JE. Viral and bacterial infections in the development and progression of asthma. J Allergy Clin Immunol 105(pt. 2):S497-S502, 2000.
3. Frieri M. Advances in the understanding allergic asthma. Allergy Asthma Proc 28:614-619, 2007.
4. Coleman AT, Jackson DJ, Gangnon RE, et al. Comparison of risk factors for viral and nonviral asthma exacerbations. J Allergy Clin Immunol 136:1127-1129.e4, 2015.
5. Gern JE. Promising candidates for allergy prevention. J Allergy Clin Immunol 136:23-28, 2015.
6. Frieri M. Asthma linked with rhinosinusitis: An extensive review. Allergy Rhinol (Providence) 5:41-49, 2014.
7. Cui L, Morris A, and Huang L. The microbiome and the lung. Ann Am Thorac Soc 11(suppl. 4):S227-S232, 2014.
8. Liang Z, Zhang Q, Thomas CM, et al. Impaired macrophage phagocytosis of bacteria in severe asthma. Respir Res 15:72, 2014.
9. Andréjak C, and Delhaes L. The lung microbiome in 2015: A window on chronic lung diseases [in French with English abstract]. Med Sci (Paris) 31:971-978, 2015.
10. Beck JM, Young VB, and Huffnagle GB. The microbiome of the lung. Transl Res 160:258-266, 2012.
11. Chanez P, Wenzel SE, Anderson GP, et al. Severe asthma in adults: What are the important questions? J Allergy Clin Immunol 119:1337-1348, 2007.
12. Ottenheim C, Meier K, Zimmermann W, and Wu JC. Isolation of filamentous fungi exhibiting high endoxylanase activity in lignocellulose hydrolysate. Appl Biochem Biotechnol 175:2066-2074, 2015.
13. Pashley CH, Fairs A, Morley JP, et al. Routine processing procedures for isolating filamentous fungi from respiratory sputum samples may underestimate fungal prevalence. Med Mycol 50:433-438, 2012.
14. Knutsen AP, Bush RK, Demain JG, et al. Fungi and allergic lower respiratory tract diseases. J Allergy Clin Immunol 129:280-291; quiz 292-293, 2012.
15. Zhu L, Lee B, Zhao F, et al. Modulation of airway epithelial antiviral immunity by fungal exposure. Am J Respir Cell Mol Biol 50:1136-1143, 2014.
16. Kolwijck E, and van de Veerdonk FL. The potential impact of the pulmonary microbiome on immunopathogenesis of Aspergillus-related lung disease. Eur J Immunol 44:3156-3165, 2014.
17. Schütze N, Lehmann I, Bönisch U, et al. Exposure to mycotoxins increases the allergic immune response in a murine asthma model. Am J Respir Crit Care Med 181:1188-1199, 2010.
18. Bateman ED, Boushey HA, Bousquet J, et al. GOAL Investigators Group. Can guideline-defined asthma control be achieved? The Gaining Optimal Asthma ControL Study. Am J Respir Crit Care Med 170:836-844, 2004.
19. Leung TF, Ko FW, and Wong GW. Recent advances in asthma biomarker research. Ther Adv Respir Dis 7:297-308, 2013.
20. Ibrahim B, Marsden P, Smith JA, et al. Breath metabolomic profiling by nuclear magnetic resonance spectroscopy in asthma. Allergy 68:1050-1056, 2013.
21. Carpagnano GE, Spanevello A, Beghe B, et al. Microsatellite alterations suggestive of organ-specific asthma and atopy in exhaled breath condensate. Allergy 65:404-405, 2010.
22. Carraro S, Giordano G, Reniero F, et al. Asthma severity in childhood and metabolomic profiling of breath condensate. Allergy 68:110-117, 2013.
23. Carpagnano GE, Lacedonia D, Palladino GP, et al. Aspergillus spp. colonization in exhaled breath condensate of lung cancer patients from Puglia Region of Italy. BMC Pulm Med 14:22, 2014.
24. Spanevello A, Confalonieri M, Sulotto F, et al. Induced sputum cellularity. Reference values and distribution in normal volunteers. Am J Respir Crit Care Med 162(pt. 1):1172-1174, 2000.
25. Carpagnano GE, Foschino Barbaro MP, Cagnazzo M, et al. Use of exhaled breath condensate in the study of airway inflammation after hypertonic saline solution challenge. Chest 128:3159-3166, 2005.
26. Zukiewicz-Sobczak W, Sobczak P, Krasowska E, et al. Allergenic potential of moulds isolated from buildings. Ann Agric Environ Med 20:500-503, 2013.
27. American Thoracic Society, European Respiratory Society. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med 171:912-930, 2005.
28. Kharitonov SA, Gonio F, Kelly C, et al. Reproducibility of exhaled nitric oxide measurements in healthy and asthmatic adults and children. Eur Respir J 21:433-438, 2003.
29. Herman C, and Cetingul MP. Quantitative visualization and detection of skin cancer using dynamic thermal imaging. J Vis Exp 5: pii: 2679, 2011.
30. Piacentini GL, Bodini A, Zerman L, et al. Relationship between exhaled air temperature and exhaled nitric oxide in childhood asthma. Eur Respir J 20:108-111, 2002.
31. Huang YJ, Nariya S, Harris JM, et al. The airway microbiome in patients with severe asthma: Associations with disease features and severity. J Allergy Clin Immunol 136:874-884, 2015.
32. Malik H, Kumar K, Fogel J, and Frieri M. Obesity is associated with asthma in patients from an undeserved low physician to patient ratio area in a New York pediatric emergency department. Internet Journal of Pulmonary Medicine 13:1-5, 2012.
33. Kettleson EM, Adhikari A, Vesper S, et al. Key determinants of the fungal and bacterial microbiomes in homes. Environ Res 138:130-135, 2015.
34. Sharpe RA, Bearman N, and Thornton CR. Indoor fungal diversity and asthma: A meta-analysis and systematic review of risk factors. J Allergy Clin Immunol 135:110-122, 2015.
35. Lau A, Chen S, Sorrell T, et al. Development and clinical application of a panfungal PCR assay to detect and identify fungal DNA in tissue specimens. J Clin Microbiol 45:380-385, 2007.