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European Union, Regulation (EC) No 1907/2006 of the European Parliament and of the Council, of 18 December 2006 concerning the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission.
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Regulation (EC) No 1907/2006 of the European Parliament and of the Council, of 18 December 2006 concerning the Registration, Evaluation, Authorization and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission
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A strategy for constructing and reporting a read-across prediction of toxicity
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The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study
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N.Ball, M.Bartels, R.Budinsky, J.Klapacz, S.Hays, and C.Kirman, The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study, Regul. Toxicol. Pharmacol. 68 (2014), pp. 212–221.
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Assessment of in silico models for acute aquatic toxicity towards fish under REACH legislation
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C.I.Cappelli, A.Cassano, A.Golbamaki, Y.Moggio, A.Lombardo, M.Colafranceschi, and E.Benfenati, Assessment of in silico models for acute aquatic toxicity towards fish under REACH legislation, SAR QSAR Environ. Res. 26 (2015), pp. 977–999.
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Evaluation of QSAR models for predicting the partition coefficient (log P) of chemicals under the REACH regulation
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C.I.Cappelli, E.Benfenati, and J.Cester, Evaluation of QSAR models for predicting the partition coefficient (log P) of chemicals under the REACH regulation, Environ. Res. 143 (2015), pp. 26–32.
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Cappelli, C.I.1
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Validation of quantitative structure-activity relationships models to predict water-solubility of organic compounds
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C.I.Cappelli, S.Manganelli, A.Lombardo, A.Gissi, and E.Benfenati, Validation of quantitative structure-activity relationships models to predict water-solubility of organic compounds, Sci. Total Environ. 463-464 (2013), pp. 781–789.
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Comparison between bioconcentration factor (BCF) data provided by industry to the European Chemicals Agency (ECHA) and data derived from QSAR models
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M.I.Petoumenou, F.Pizzo, J.Cester, A.Fernández, and E.Benfenati, Comparison between bioconcentration factor (BCF) data provided by industry to the European Chemicals Agency (ECHA) and data derived from QSAR models, Environ. Res. 142 (2015), pp. 529–534.
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Evaluation of QSAR models for the prediction of Ames genotoxicity: A retrospective exercise on the chemical substances registered under the EU REACH regulation, J. Environ. Sci. Health C
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A.Cassano, G.Raitano, E.Mombelli, A.Fernández, J.Cester, A.Roncaglioni, and E.Benfenati, Evaluation of QSAR models for the prediction of Ames genotoxicity: A retrospective exercise on the chemical substances registered under the EU REACH regulation, J. Environ. Sci. Health C, Environ. Carcinog. Ecotoxicol. Rev. 32 (2014), pp. 273–298.
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Evaluation and comparison of benchmark QSAR models to predict a relevant REACH endpoint: The bioconcentration factor (BCF)
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A.Gissi, A.Lombardo, A.Roncaglioni, D.Gadaleta, G.F.Mangiatordi, O.Nicolotti, and E.Benfenati, Evaluation and comparison of benchmark QSAR models to predict a relevant REACH endpoint: The bioconcentration factor (BCF), Environ. Res. 137 (2015), pp. 398–409.
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Comparison of in silico tools for evaluating rat oral acute toxicity
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R.Gonella Diaza, S.Manganelli, A.Esposito, A.Roncaglioni, A.Manganaro, and E.Benfenati, Comparison of in silico tools for evaluating rat oral acute toxicity, SAR QSAR Environ. Res. 26 (2015), pp. 1–27.
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Comparison of in silico models for prediction of mutagenicity, J. Environ. Sci. Health. C
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N.Golbamaki Bakhtyari, G.Raitano, E.Benfenati, and T.M.Martin, and D.Young, Comparison of in silico models for prediction of mutagenicity, J. Environ. Sci. Health. C, Environ. Carcinog. Ecotoxicol. Rev. 31 (2013), pp. 45–66.
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Comparison and possible use of in silico tools for carcinogenicity within REACH legislation
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C.Milan, O.Schifanella, A.Roncaglioni, and E.Benfenati, Comparison and possible use of in silico tools for carcinogenicity within REACH legislation, J. Environ. Sci. Health. C. 29 (2011), pp. 300–323.
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In silico models for predicting ready biodegradability under REACH: A comparative study
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F.Pizzo, A.Lombardo, A.Manganaro, and E.Benfenati, In silico models for predicting ready biodegradability under REACH: A comparative study, Sci. Total Environ. 463–464 (2013), pp. 161–168.
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G.Gini, A.M.Franchi., A.Manganaro, A.Golbamaki, and E.Benfenati, ToxRead: A tool to assist in read-across and its use to assess mutagenicity of chemicals, SAR QSAR Environ. Res. 25 (2014), pp. 999–1011.
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Integrating QSAR and read-across for environmental assessmen
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E.Benfenati, S.Manganelli, S.Giordano, G.Raitano, and A.Manganaro, Hierarchical rules for read-across and in silico models of mutagenicity, J. Environ. Sci. Health C, Environ. Carcinog. Ecotoxicol. Rev. 33 (2015), pp. 385–403.
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