메뉴 건너뛰기




Volumn 46, Issue 3, 2016, Pages 270-278

Reduced Immunocompetent B Cells and Increased Secondary Infection in Elderly Patients with Severe Sepsis

Author keywords

Aging; B cells; exhaustion; immunoglobulin M; immunosuppression; sepsis

Indexed keywords

IMMUNOGLOBULIN M;

EID: 84966708393     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000619     Document Type: Article
Times cited : (49)

References (35)
  • 1
    • 84891652126 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis
    • Mayr FB, Yende S, Angus DC: Epidemiology of severe sepsis. Virulence 5(1):4-11, 2014.
    • (2014) Virulence , vol.5 , Issue.1 , pp. 4-11
    • Mayr, F.B.1    Yende, S.2    Angus, D.C.3
  • 11
    • 84858796247 scopus 로고    scopus 로고
    • Integration of B cell responses through Toll-like receptors and antigen receptors
    • Rawlings DJ, Schwartz MA, Jackson SW, Meyer-Bahlburg A: Integration of B cell responses through Toll-like receptors and antigen receptors. Nat Rev Immunol 12(4):282-294, 2012.
    • (2012) Nat Rev Immunol , vol.12 , Issue.4 , pp. 282-294
    • Rawlings, D.J.1    Ma, S.2    Jackson, S.W.3    Meyer-Bahlburg, A.4
  • 12
    • 46049112339 scopus 로고    scopus 로고
    • Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals
    • Moir S, Ho J, Malaspina A, Wang W, DiPoto AC, O'Shea MA, Roby G, Kottilil S, Arthos J, Proschan MA, et al.: Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals. J Exp Med 205(8):1797-1805, 2008.
    • (2008) J Exp Med , vol.205 , Issue.8 , pp. 1797-1805
    • Moir, S.1    Ho, J.2    Malaspina, A.3    Wang, W.4    DiPoto, A.C.5    Ma, O.6    Roby, G.7    Kottilil, S.8    Arthos, J.9    Ma, P.10
  • 13
    • 84892465329 scopus 로고    scopus 로고
    • Peripheral CD27-CD21-B-cells represent an exhausted lymphocyte population in hepatitis C cirrhosis
    • Doi H, Tanoue S, Kaplan DE: Peripheral CD27-CD21-B-cells represent an exhausted lymphocyte population in hepatitis C cirrhosis. Clin Immunol 150(2):184-191, 2014.
    • (2014) Clin Immunol , vol.150 , Issue.2 , pp. 184-191
    • Doi, H.1    Tanoue, S.2    De, K.3
  • 15
    • 63149142646 scopus 로고    scopus 로고
    • B cells in HIV infection and disease
    • Moir S, Fauci AS: B cells in HIV infection and disease. Nat Rev Immunol 9(4):235-245, 2009.
    • (2009) Nat Rev Immunol , vol.9 , Issue.4 , pp. 235-245
    • Moir, S.1    Fauci, A.S.2
  • 16
    • 0026710191 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
    • Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, Schein RM, Sibbald WJ: Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101(6):1644-1655, 1992.
    • (1992) Chest , vol.101 , Issue.6 , pp. 1644-1655
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3    Dellinger, R.P.4    Fein, A.M.5    Knaus, W.A.6    Schein, R.M.7    Sibbald, W.J.8
  • 19
    • 0034671980 scopus 로고    scopus 로고
    • A role for CD21/CD35 and CD19 in responses to acute septic peritonitis: A potential mechanism for mast cell activation
    • Gommerman JL, Oh DY, Zhou X, Tedder TF, Maurer M, Galli SJ, Carroll MC: A role for CD21/CD35 and CD19 in responses to acute septic peritonitis: a potential mechanism for mast cell activation. J Immunol 165(12):6915-6921, 2000.
    • (2000) J Immunol , vol.165 , Issue.12 , pp. 6915-6921
    • Gommerman, J.L.1    Oh, D.Y.2    Zhou, X.3    Tedder, T.F.4    Maurer, M.5    Galli, S.J.6    Carroll, M.C.7
  • 20
    • 0035026505 scopus 로고    scopus 로고
    • Increased apoptosis in lamina propria B cells during polymicrobial sepsis is FasL but not endotoxin mediated
    • Chung CS, Wang W, Chaudry IH, Ayala A: Increased apoptosis in lamina propria B cells during polymicrobial sepsis is FasL but not endotoxin mediated. Am J Physiol Gastrointest Liver Physiol 280(5):G812-G818, 2001.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280 , Issue.5 , pp. G812-G818
    • Chung, C.S.1    Wang, W.2    Chaudry, I.H.3    Ayala, A.4
  • 22
    • 0032445137 scopus 로고    scopus 로고
    • A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection
    • Boes M, Prodeus AP, Schmidt T, Carroll MC, Chen J: A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection. J Exp Med 188(12):2381-2386, 1998.
    • (1998) J Exp Med , vol.188 , Issue.12 , pp. 2381-2386
    • Boes, M.1    Prodeus, A.P.2    Schmidt, T.3    Carroll, M.C.4    Chen, J.5
  • 23
    • 34548822435 scopus 로고    scopus 로고
    • LPS pretreatment by the oral route protects against sepsis induced by cecal ligation and puncture. Regulation of proinflammatory response and IgM anti-LPS antibody production as associated mechanisms
    • Marquez-Velasco R, Masso F, Hernandez-Pando R, Montano LF, Springall R, Amezcua-Guerra LM, Bojalil R: LPS pretreatment by the oral route protects against sepsis induced by cecal ligation and puncture. Regulation of proinflammatory response and IgM anti-LPS antibody production as associated mechanisms. Inflamm Res 56(9):385-390, 2007.
    • (2007) Inflamm Res , vol.56 , Issue.9 , pp. 385-390
    • Marquez-Velasco, R.1    Masso, F.2    Hernandez-Pando, R.3    Montano, L.F.4    Springall, R.5    Amezcua-Guerra, L.M.6    Bojalil, R.7
  • 24
    • 79961171990 scopus 로고    scopus 로고
    • Aging affects human B cell responses
    • Frasca D, Blomberg BB: Aging affects human B cell responses. J Clin Immunol 31(3):430-435, 2011.
    • (2011) J Clin Immunol , vol.31 , Issue.3 , pp. 430-435
    • Frasca, D.1    Blomberg, B.B.2
  • 25
    • 11144267995 scopus 로고    scopus 로고
    • Age-related loss of naive T cells and dysregulation of T-cell/B-cell interactions in human lymph nodes
    • Lazuardi L, Jenewein B, Wolf AM, Pfister G, Tzankov A, Grubeck-Loebenstein B: Age-related loss of naive T cells and dysregulation of T-cell/B-cell interactions in human lymph nodes. Immunology 114(1):37-43, 2005.
    • (2005) Immunology , vol.114 , Issue.1 , pp. 37-43
    • Lazuardi, L.1    Jenewein, B.2    Wolf, A.M.3    Pfister, G.4    Tzankov, A.5    Grubeck-Loebenstein, B.6
  • 26
    • 23844467731 scopus 로고    scopus 로고
    • Regulation of aged humoral immune defense against pneumococcal bacteria by IgM memory B cell
    • Shi Y, Yamazaki T, Okubo Y, Uehara Y, Sugane K, Agematsu K: Regulation of aged humoral immune defense against pneumococcal bacteria by IgM memory B cell. J Immunol 175(5):3262-3267, 2005.
    • (2005) J Immunol , vol.175 , Issue.5 , pp. 3262-3267
    • Shi, Y.1    Yamazaki, T.2    Okubo, Y.3    Uehara, Y.4    Sugane, K.5    Agematsu, K.6
  • 30
    • 0028928641 scopus 로고
    • Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis
    • Kawano MM, Mihara K, Huang N, Tsujimoto T, Kuramoto A: Differentiation of early plasma cells on bone marrow stromal cells requires interleukin-6 for escaping from apoptosis. Blood 85(2):487-494, 1995.
    • (1995) Blood , vol.85 , Issue.2 , pp. 487-494
    • Kawano, M.M.1    Mihara, K.2    Huang, N.3    Tsujimoto, T.4    Kuramoto, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.