Binding of Janus kinase inhibitor tofacitinib with human serum albumin: multi-technique approach

Journal of Biomolecular Structure and Dynamics

Volumn 34, Issue 9, 2016, Pages 2037-2044

  Abdelhameed, Ali S ^a   Alam, Parvez ^b   Khan, Rizwan Hasan ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

binding; fluorescence quenching; molecular docking; serum albumin

Indexed keywords

HUMAN SERUM ALBUMIN; TOFACITINIB; JANUS KINASE; PIPERIDINE DERIVATIVE; PROTEIN BINDING; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; SERUM ALBUMIN;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; DIFFERENTIAL SCANNING CALORIMETRY; DRUG BINDING SITE; DRUG PROTEIN BINDING; FLUORESCENCE ANALYSIS; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DOCKING; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN STABILITY; THERMOSTABILITY; ULTRAVIOLET SPECTROSCOPY; ANTAGONISTS AND INHIBITORS; CHEMISTRY; CIRCULAR DICHROISM; CONFORMATION; HUMAN; METABOLISM; MOLECULAR DYNAMICS; MOLECULAR MODEL; PH; SPECTROFLUOROMETRY; STRUCTURE ACTIVITY RELATION; THERMODYNAMICS;

CALORIMETRY, DIFFERENTIAL SCANNING; CIRCULAR DICHROISM; HUMANS; HYDROGEN-ION CONCENTRATION; JANUS KINASES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR DOCKING SIMULATION; MOLECULAR DYNAMICS SIMULATION; PIPERIDINES; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PYRIMIDINES; PYRROLES; SERUM ALBUMIN; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; THERMODYNAMICS;

EID: 84966700844     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2015.1104522     Document Type: Article

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