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Volumn 36, Issue 5, 2016, Pages 881-888

Pigment epithelial detachment response to Aflibercept in Neovascular age-related macular degeneration refractory to Ranibizumab

Author keywords

aflibercept; angiogenesis; antiangiogenic drugs; intravitreal injection; neovascular age related macular degeneration; ranibizumab; refractoriness; retinal pigment epithelial detachment; vascular endothelial growth factor; visual impairment

Indexed keywords

AFLIBERCEPT; RANIBIZUMAB; ANGIOGENESIS INHIBITOR; HYBRID PROTEIN; VASCULOTROPIN A; VASCULOTROPIN RECEPTOR; VEGFA PROTEIN, HUMAN;

EID: 84966508433     PISSN: 0275004X     EISSN: 15392864     Source Type: Journal    
DOI: 10.1097/IAE.0000000000000813     Document Type: Article
Times cited : (23)

References (41)
  • 1
    • 57949094834 scopus 로고    scopus 로고
    • Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: Two-year results of the ANCHOR study
    • Brown DM, Michels M, Kaiser PK, et al. Ranibizumab versus verteporfin photodynamic therapy for neovascular age-related macular degeneration: two-year results of the ANCHOR study. Ophthalmology 2009; 116: 57-65
    • (2009) Ophthalmology , vol.116 , pp. 57-65
    • Brown, D.M.1    Michels, M.2    Kaiser, P.K.3
  • 2
    • 33749445317 scopus 로고    scopus 로고
    • Ranibizumab for neovascular age-related macular degeneration
    • Rosenfeld PJ, Brown DM, Heier JS. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006; 355: 1419-1431
    • (2006) N Engl J Med , vol.355 , pp. 1419-1431
    • Rosenfeld, P.J.1    Brown, D.M.2    Heier, J.S.3
  • 3
    • 84870723704 scopus 로고    scopus 로고
    • Intravitreal aflibercept (VEGF Trap-eye) in wet age-related macular degeneration
    • Heier JS, Brown DM, Chong V, et al. Intravitreal aflibercept (VEGF Trap-eye) in wet age-related macular degeneration. Ophthalmology 2012; 119: 2537-2548
    • (2012) Ophthalmology , vol.119 , pp. 2537-2548
    • Heier, J.S.1    Brown, D.M.2    Chong, V.3
  • 4
    • 84891631034 scopus 로고    scopus 로고
    • Intravitreal aflibercept injection for neovascular age-related macular degeneration
    • Schmidt-Erfurth U, Kaiser PK, Korobelnik JF, et al. Intravitreal aflibercept injection for neovascular age-related macular degeneration. Ophthalmology 2014; 121: 193-201
    • (2014) Ophthalmology , vol.121 , pp. 193-201
    • Schmidt-Erfurth, U.1    Kaiser, P.K.2    Korobelnik, J.F.3
  • 5
    • 84865129521 scopus 로고    scopus 로고
    • Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF trap, ranibizumab and bevacizumab
    • Papadopoulos N, Martin J, Ruan Q, et al. Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF trap, ranibizumab and bevacizumab. Angiogenesis 2012; 15: 171-185
    • (2012) Angiogenesis , vol.15 , pp. 171-185
    • Papadopoulos, N.1    Martin, J.2    Ruan, Q.3
  • 6
    • 43649083100 scopus 로고    scopus 로고
    • Predicted biological activity of intravitreal VEGF trap
    • Stewart MW, Rosenfeld PJ. Predicted biological activity of intravitreal VEGF trap. Br J Ophthalmol 2008; 92: 667-668
    • (2008) Br J Ophthalmol , vol.92 , pp. 667-668
    • Stewart, M.W.1    Rosenfeld, P.J.2
  • 7
    • 84879235232 scopus 로고    scopus 로고
    • Aflibercept therapy for exudative age-related macular degeneration resistant to bevacizumab and ranibizumab
    • Bakall B, Folk JC, Boldt HC, et al. Aflibercept therapy for exudative age-related macular degeneration resistant to bevacizumab and ranibizumab. Am J Ophthalmol 2013; 156: 15-22
    • (2013) Am J Ophthalmol , vol.156 , pp. 15-22
    • Bakall, B.1    Folk, J.C.2    Boldt, H.C.3
  • 8
    • 84880005310 scopus 로고    scopus 로고
    • Aflibercept for exudative AMD with persistent fluid on ranibizumab and/or bevacizumab
    • Cho H, Shah CP, Weber M, et al. Aflibercept for exudative AMD with persistent fluid on ranibizumab and/or bevacizumab. Br J Ophthalmol 2013; 97: 1032-1035
    • (2013) Br J Ophthalmol , vol.97 , pp. 1032-1035
    • Cho, H.1    Shah, C.P.2    Weber, M.3
  • 9
    • 84879209123 scopus 로고    scopus 로고
    • Short-term outcomes of aflibercept for neovascular age-related macular degeneration in eyes previously treated with other vascular endothelial growth factor inhibitors
    • Ho VY, Yeh S, Olsen TW, et al. Short-term outcomes of aflibercept for neovascular age-related macular degeneration in eyes previously treated with other vascular endothelial growth factor inhibitors. Am J Ophthalmol 2013; 156: 23-28
    • (2013) Am J Ophthalmol , vol.156 , pp. 23-28
    • Ho, V.Y.1    Yeh, S.2    Olsen, T.W.3
  • 10
    • 84877665569 scopus 로고    scopus 로고
    • Rapid response of retinal pigment epithelial detachments to intravitreal aflibercept in neovascular age-related macular degeneration refractory to bevacizumab and ranibizumab
    • Patel KH, Chow CC, Rathod R, et al. Rapid response of retinal pigment epithelial detachments to intravitreal aflibercept in neovascular age-related macular degeneration refractory to bevacizumab and ranibizumab. Eye (Lond) 2013; 27: 663-668
    • (2013) Eye (Lond) , vol.27 , pp. 663-668
    • Patel, K.H.1    Chow, C.C.2    Rathod, R.3
  • 11
    • 84879203732 scopus 로고    scopus 로고
    • Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration
    • Yonekawa Y, Andreoli C, Miller JB, et al. Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration. Am J Ophthalmol 2013; 156: 29-35
    • (2013) Am J Ophthalmol , vol.156 , pp. 29-35
    • Yonekawa, Y.1    Andreoli, C.2    Miller, J.B.3
  • 12
    • 84922020078 scopus 로고    scopus 로고
    • Visual and anatomical outcomes following intravitreal aflibercept in eyes with recalcitrant neovascular age-related macular degeneration: 12- month results
    • Grewal DS, Gill MK, Sarezky D, et al. Visual and anatomical outcomes following intravitreal aflibercept in eyes with recalcitrant neovascular age-related macular degeneration: 12- month results. Eye (Lond) 2014; 28: 895-899
    • (2014) Eye (Lond) , vol.28 , pp. 895-899
    • Grewal, D.S.1    Gill, M.K.2    Sarezky, D.3
  • 13
    • 84902245557 scopus 로고    scopus 로고
    • Clinical outcomes after switching treatment from intravitreal ranibizumab to aflibercept in neovascular age-related macular degeneration
    • Heussen FM, Shao Q, Ouyang Y, et al. Clinical outcomes after switching treatment from intravitreal ranibizumab to aflibercept in neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 2013; 252: 909-915
    • (2013) Graefes Arch Clin Exp Ophthalmol , vol.252 , pp. 909-915
    • Heussen, F.M.1    Shao, Q.2    Ouyang, Y.3
  • 14
    • 84902362487 scopus 로고    scopus 로고
    • Aflibercept treatment for patients with exudative age-related macular degeneration who were incomplete responders to multiple ranibizumab injections (TURF trial).
    • Wykoff CC, Brown DM, Maldonado ME, Croft DE. Aflibercept treatment for patients with exudative age-related macular degeneration who were incomplete responders to multiple ranibizumab injections (TURF trial). Br J Ophthalmol 2014; 98: 951-955
    • (2014) Br J Ophthalmol , vol.98 , pp. 951-955
    • Wykoff, C.C.1    Brown, D.M.2    Maldonado, M.E.3    Croft, D.E.4
  • 15
    • 84901762313 scopus 로고    scopus 로고
    • Visual and anatomical outcomes of intravitreal aflibercept for treatment-resistant neovascular age-related macular degeneration
    • Gharbiya M, Iannetti L, Parisi F, et al. Visual and anatomical outcomes of intravitreal aflibercept for treatment-resistant neovascular age-related macular degeneration. Biomed Res Int 2014; 2014: 813-825
    • (2014) Biomed Res Int , vol.2014 , pp. 813-825
    • Gharbiya, M.1    Iannetti, L.2    Parisi, F.3
  • 16
    • 84929049456 scopus 로고    scopus 로고
    • Response of pigment epithelial detachments to intravitreal aflibercept among patients with treatment-resistant neovascular age-related macular degeneration
    • Broadhead GK, Hong T, Zhu M, et al. Response of pigment epithelial detachments to intravitreal aflibercept among patients with treatment-resistant neovascular age-related macular degeneration. Retina 2015; 35: 975-981
    • (2015) Retina , vol.35 , pp. 975-981
    • Broadhead, G.K.1    Hong, T.2    Zhu, M.3
  • 17
    • 84922675324 scopus 로고    scopus 로고
    • One-year outcomes of aflibercept in recurrent or persistent neovascular age-related macular degeneration
    • Arcinue CA, Ma F, Barteselli G, et al. One-year outcomes of aflibercept in recurrent or persistent neovascular age-related macular degeneration. Am J Ophthalmol 2015; 159: 426-436
    • (2015) Am J Ophthalmol , vol.159 , pp. 426-436
    • Arcinue, C.A.1    Ma, F.2    Barteselli, G.3
  • 18
    • 84891632111 scopus 로고    scopus 로고
    • Intravitreal aflibercept for treatment-resistant neovascular age-related macular degeneration
    • Chang AA, Li H, Broadhead GK, et al. Intravitreal aflibercept for treatment-resistant neovascular age-related macular degeneration. Ophthalmology 2014; 121: 188-192
    • (2014) Ophthalmology , vol.121 , pp. 188-192
    • Chang, A.A.1    Li, H.2    Broadhead, G.K.3
  • 19
    • 84883740682 scopus 로고    scopus 로고
    • Visual and anatomical outcomes of intravitreal aflibercept in eyes with persistent subfoveal fluid despite previous treatments with ranibizumab in patients with neovascular age-related macular degeneration
    • Kumar N, Marsiglia M, Mrejen S, et al. Visual and anatomical outcomes of intravitreal aflibercept in eyes with persistent subfoveal fluid despite previous treatments with ranibizumab in patients with neovascular age-related macular degeneration. Retina 2013; 33: 1605-1612
    • (2013) Retina , vol.33 , pp. 1605-1612
    • Kumar, N.1    Marsiglia, M.2    Mrejen, S.3
  • 20
    • 84924218447 scopus 로고    scopus 로고
    • Quantitative OCT subanalysis of eyes with choroidal neovascularization switched from multiple injections of bevacizumab or ranibizumab to intravitreal aflibercept
    • Hariri A, Diniz B, Fou LV, et al. Quantitative OCT subanalysis of eyes with choroidal neovascularization switched from multiple injections of bevacizumab or ranibizumab to intravitreal aflibercept. Ophthalmic Surg Lasers Imaging Retina 2015; 46: 195-200
    • (2015) Ophthalmic Surg Lasers Imaging Retina , vol.46 , pp. 195-200
    • Hariri, A.1    Diniz, B.2    Fou, L.V.3
  • 21
    • 0036951480 scopus 로고    scopus 로고
    • Pigment epithelial detachment in the elderly Clinical differentiation, natural course and pathogenetic implications
    • Pauleikhoff D, Löffert D, Spital G, et al. Pigment epithelial detachment in the elderly. Clinical differentiation, natural course and pathogenetic implications. Graefes Arch Clin Exp Ophthalmol 2002; 240: 533-538
    • (2002) Graefes Arch Clin Exp Ophthalmol , vol.240 , pp. 533-538
    • Pauleikhoff, D.1    Löffert, D.2    Spital, G.3
  • 22
    • 84880008611 scopus 로고    scopus 로고
    • Imaging characteristics of neovascular pigment epithelial detachments and their response to anti-vascular endothelial growth factor therapy
    • Punjabi OS, Huang J, Rodriguez L, et al. Imaging characteristics of neovascular pigment epithelial detachments and their response to anti-vascular endothelial growth factor therapy. Br J Ophthalmol 2013; 97: 1024-1031
    • (2013) Br J Ophthalmol , vol.97 , pp. 1024-1031
    • Punjabi, O.S.1    Huang, J.2    Rodriguez, L.3
  • 23
    • 84885019016 scopus 로고    scopus 로고
    • Alterations of vascular pigment epithelium detachments associated with age-related macular degeneration during upload with intravitreal ranibizumab
    • Wolf A, Rüping J, Neubauer AS, et al. Alterations of vascular pigment epithelium detachments associated with age-related macular degeneration during upload with intravitreal ranibizumab. Retina 2013; 33: 1843-1849
    • (2013) Retina , vol.33 , pp. 1843-1849
    • Wolf, A.1    Rüping, J.2    Neubauer, A.S.3
  • 24
    • 19244379078 scopus 로고    scopus 로고
    • Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
    • Carmeliet P, Moons L, Luttun A, et al. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med 2001; 7: 575-583
    • (2001) Nat Med , vol.7 , pp. 575-583
    • Carmeliet, P.1    Moons, L.2    Luttun, A.3
  • 25
    • 0033956368 scopus 로고    scopus 로고
    • Placenta growth factor (PlGF) induces vascular endothelial growth factor (VEGF) secretion from mononuclear cells and is coexpressed with VEGF in synovial fluid
    • Bottomley MJ, Webb NJA, Watson CJ, et al. Placenta growth factor (PlGF) induces vascular endothelial growth factor (VEGF) secretion from mononuclear cells and is coexpressed with VEGF in synovial fluid. Clin Exp Immunol 2000; 119: 182-188
    • (2000) Clin Exp Immunol , vol.119 , pp. 182-188
    • Bottomley, M.J.1    Nja, W.2    Watson, C.J.3
  • 26
    • 0037900481 scopus 로고    scopus 로고
    • Placental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization
    • Rakic JM, Lambert V, Devy L, et al. Placental growth factor, a member of the VEGF family, contributes to the development of choroidal neovascularization. Invest Ophthalmol Vis Sci 2003; 44: 3186-3193
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 3186-3193
    • Rakic, J.M.1    Lambert, V.2    Devy, L.3
  • 27
    • 0036187554 scopus 로고    scopus 로고
    • Altered expression patterns of VEGF receptors in human diabetic retina and in experimental VEGF-induced retinopathy in monkey
    • Witmer AN, Blaauwgeers HG, Weich HA, et al. Altered expression patterns of VEGF receptors in human diabetic retina and in experimental VEGF-induced retinopathy in monkey. Invest Ophthalmol Vis Sci 2002; 43: 849-857
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 849-857
    • Witmer, A.N.1    Blaauwgeers, H.G.2    Weich, H.A.3
  • 28
    • 0036237998 scopus 로고    scopus 로고
    • Regulation of retinal vascular endothelial growth factor and receptors in rabbits exposed to hyperoxia
    • Ozaki NK, Beharry KD, Nishihara KC, et al. Regulation of retinal vascular endothelial growth factor and receptors in rabbits exposed to hyperoxia. Invest Ophthalmol Vis Sci 2002; 43: 1546-1557
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 1546-1557
    • Ozaki, N.K.1    Beharry, K.D.2    Nishihara, K.C.3
  • 29
    • 0032961301 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor and its receptor (KDR/flk-1) mRNA in experimental choroidal neovascularization
    • Wada M, Ogata N, Otsuji T, Uyama M. Expression of vascular endothelial growth factor and its receptor (KDR/flk-1) mRNA in experimental choroidal neovascularization. Curr Eye Res 1999; 18: 203-213
    • (1999) Curr Eye Res , vol.18 , pp. 203-213
    • Wada, M.1    Ogata, N.2    Otsuji, T.3    Uyama, M.4
  • 30
    • 0032807809 scopus 로고    scopus 로고
    • Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation
    • Blaauwgeers HG, Holtkamp GM, Rutten H, et al. Polarized vascular endothelial growth factor secretion by human retinal pigment epithelium and localization of vascular endothelial growth factor receptors on the inner choriocapillaris. Evidence for a trophic paracrine relation. Am J Pathol 1999; 155: 421-428
    • (1999) Am J Pathol , vol.155 , pp. 421-428
    • Blaauwgeers, H.G.1    Holtkamp, G.M.2    Rutten, H.3
  • 31
    • 84901606839 scopus 로고    scopus 로고
    • Different effects of intravitreally injected ranibizumab and aflibercept on retinal and choroidal tissues of monkey eyes
    • Julien S, Biesemeier A, Taubitz T, Schraermeyer U. Different effects of intravitreally injected ranibizumab and aflibercept on retinal and choroidal tissues of monkey eyes. Br J Ophthalmol 2014; 98: 813-825
    • (2014) Br J Ophthalmol , vol.98 , pp. 813-825
    • Julien, S.1    Biesemeier, A.2    Taubitz, T.3    Schraermeyer, U.4
  • 32
    • 0028349871 scopus 로고
    • Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane
    • Holz FG, Sheraidah G, Pauleikhoff D, Bird AC. Analysis of lipid deposits extracted from human macular and peripheral Bruch's membrane. Arch Ophthalmol 1994; 112: 402-406
    • (1994) Arch Ophthalmol , vol.112 , pp. 402-406
    • Holz, F.G.1    Sheraidah, G.2    Pauleikhoff, D.3    Bird, A.C.4
  • 33
    • 48249144751 scopus 로고    scopus 로고
    • Quantitative subanalysis of optical coherence tomography after treatment with ranibizumab for neovascular age-related macular degeneration
    • Keane PA, Liakopoulos S, Ongchin SC, et al. Quantitative subanalysis of optical coherence tomography after treatment with ranibizumab for neovascular age-related macular degeneration. Invest Ophthalmol Vis Sci 2008; 49: 3115-3120
    • (2008) Invest Ophthalmol Vis Sci , vol.49 , pp. 3115-3120
    • Keane, P.A.1    Liakopoulos, S.2    Ongchin, S.C.3
  • 34
    • 84455206370 scopus 로고    scopus 로고
    • Bevacizumab and ranibizumab tachyphylaxis in the treatment of choroidal neovascularisation
    • Gasperini JL, Fawzi AA, Khondkaryan A, et al. Bevacizumab and ranibizumab tachyphylaxis in the treatment of choroidal neovascularisation. Br J Ophthalmol 2011; 96: 14-20
    • (2011) Br J Ophthalmol , vol.96 , pp. 14-20
    • Gasperini, J.L.1    Fawzi, A.A.2    Khondkaryan, A.3
  • 35
    • 56549111386 scopus 로고    scopus 로고
    • Is there tachyphylaxis to intravitreal anti-vascular endothelial growth factor pharmacotherapy in age-related macular degeneration?
    • Schaal S, Kaplan HJ, Tezel TH. Is there tachyphylaxis to intravitreal anti-vascular endothelial growth factor pharmacotherapy in age-related macular degeneration? Ophthalmology 2008; 115: 2199-2205
    • (2008) Ophthalmology , vol.115 , pp. 2199-2205
    • Schaal, S.1    Kaplan, H.J.2    Tezel, T.H.3
  • 37
    • 84455204035 scopus 로고    scopus 로고
    • Tachyphylaxis during treatment of exudative age-related macular degeneration with ranibizumab
    • Eghoj MS, Sorensen TL. Tachyphylaxis during treatment of exudative age-related macular degeneration with ranibizumab. Br J Ophthalmol 2011; 96: 21-23
    • (2011) Br J Ophthalmol , vol.96 , pp. 21-23
    • Eghoj, M.S.1    Sorensen, T.L.2
  • 38
    • 84924127010 scopus 로고    scopus 로고
    • Clinical risk factors for poor anatomic response to ranibizumab in neovascular agerelated macular degeneration
    • Guber J, Josifova T, Henrich PB, Guber I. Clinical risk factors for poor anatomic response to ranibizumab in neovascular agerelated macular degeneration. Open Ophthalmol J 2014; 8: 3-6
    • (2014) Open Ophthalmol J , vol.8 , pp. 3-6
    • Guber, J.1    Josifova, T.2    Henrich, P.B.3    Guber, I.4
  • 39
    • 80755153260 scopus 로고    scopus 로고
    • Characteristics of eyes with secondary loss of visual acuity receiving variable dosing ranibizumab for neovascular age-related macular degeneration
    • Mariani A, Deli A, Ambresin A, Mantel I. Characteristics of eyes with secondary loss of visual acuity receiving variable dosing ranibizumab for neovascular age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol 2011; 249: 1635-1642
    • (2011) Graefes Arch Clin Exp Ophthalmol , vol.249 , pp. 1635-1642
    • Mariani, A.1    Deli, A.2    Ambresin, A.3    Mantel, I.4
  • 40
    • 84938418571 scopus 로고    scopus 로고
    • Refractory subretinal fluid in patients with neovascular age-related macular degeneration treated with intravitreal ranibizumab: Visual acuity outcome
    • Jang L, Gianniou C, Ambresin A, Mantel I. Refractory subretinal fluid in patients with neovascular age-related macular degeneration treated with intravitreal ranibizumab: visual acuity outcome. Graefes Arch Clin Exp Ophthalmol 2015; 253: 1211-1216
    • (2015) Graefes Arch Clin Exp Ophthalmol , vol.253 , pp. 1211-1216
    • Jang, L.1    Gianniou, C.2    Ambresin, A.3    Mantel, I.4
  • 41
    • 84906937976 scopus 로고    scopus 로고
    • Fibrovascular pigment epithelial detachment is a risk factor for long-term visual decay in neovascular age-related macular degeneration
    • Hoerster R, Muether PS, Sitnilska V, et al. Fibrovascular pigment epithelial detachment is a risk factor for long-term visual decay in neovascular age-related macular degeneration. Retina 2014; 34: 1767-1773
    • (2014) Retina , vol.34 , pp. 1767-1773
    • Hoerster, R.1    Muether, P.S.2    Sitnilska, V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.