Placenta growth factor (PIGF) induces vascular endothelial growth factor (VEGF) secretion from mononuclear cells and is co-expressed with VEGF in synovial fluid

Clinical and Experimental Immunology

Volumn 119, Issue 1, 2000, Pages 182-188

  Bottomley, M J ^a   Webb, N J A ^a,b   Watson, C J ^a   Holt, L ^b   Bukhari, M ^b   Denton, J ^c   Freemont, A J ^c   Brenchley, P E C ^a,d  

^a Immunology Research   (United Kingdom)

^b Department of Child Health ^*  (United Kingdom)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

^d MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Arthritis; Heterodimers; Placenta growth factor; Synovial fluid; Vascular endothelial growth factor

Indexed keywords

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CYTOKINE PRODUCTION; FEMALE; HUMAN; IMMUNOBLOTTING; LEUKOCYTE COUNT; MALE; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN SECRETION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID LEVEL;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ARTHRITIS; CASE-CONTROL STUDIES; ENDOTHELIAL GROWTH FACTORS; FEMALE; GROWTH SUBSTANCES; HUMANS; JOINT DISEASES; LEUKOCYTE COUNT; LEUKOCYTES, MONONUCLEAR; LYMPHOKINES; MALE; MIDDLE AGED; PREGNANCY PROTEINS; SYNOVIAL FLUID; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0033956368     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.2000.01097.x     Document Type: Article

References (41)

1. 1 Jayson MIV, Dixon ASJ. Intra-articular pressure in rheumatoid arthritis of the knee. II Effect of intra-articular pressure on blood circulation to the synovium. Ann Rheum Dis 1970; 29:266-8.
2. 2 Falchuk KH, Goetzl EJ, Kulka JP. Respiratory gases of synovial fluids. An approach to synovial tissue circulatory-metabolic imbalance in rheumatoid arthritis. Am J Med 1970; 49:223-31.
3. 3 Connolly DT, Heuvelman DM, Nelson R et al. Tumour vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 1989; 84:1470-8.
4. 4 Pepper MS, Ferrara N, Orci L, Montesano R. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-I in microvascular endothelial cells. Biochem Biophys Res Commun 1991; 181:902-6.
5. 5 Unemori EN, Ferrara N, Bauer EA, Amento EP. Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J Cell Physiol 1992; 153:557-62.
6. 6 Senger DR, Ledbetter SR, Claffey KP, Papadopoulossergiou A, Perruzzi CA, Detmar M. Stimulation of endothelial cell migration by vascular permeability factor vascular endothelial growth factor through cooperative mechanisms involving the alpha (v) beta (3) integrin, osteopontin and thrombin. Am J Pathol 1996; 149:293-305.
7. 7 Connolly DT, Olander JV, Heuvelman DM et al. Human vascular permeability factor. J Biol Chem 1989; 264:20017-24.
8. 8 Fava RA, Olsen NJ, Spencer-Green G et al. Vascular permeability factor/endothelial growth factor (VPF/VEGF): accumulation and expression in human synovial fluids and rheumatoid synovial tissue. J Exp Med 1994; 180:341-6.
9. 9 Koch AE, Harlow LA, Haines GK et al. Vascular endothelial growth factor - a cytokine modulating endothelial function in rheumatoid arthritis. J Immunol 1994; 152:4149-56.
10. 10 De Vries C, Escobedo JA, Ueno H, Houck K, Ferrara N, Williams LT. The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor. Science 1992; 255:989-91.
11. 11 Terman BI, Dougher-Vermazen M, Carrion ME et al. Identification of the KDR tyrosine kinase as a receptor for vascular endothelial growth factor. BBRC 1992; 187:1579-86.
12. 12 Barleon B, Sozzani S, Zhou D, Weich HA, Mantovani A, Marme D. Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 1996; 87:3336-43.
13. 13 Disalvo J, Bayne ML, Conn G et al. Purification and characterization of a naturally occurring vascular endothelial growth factor-placenta growth factor heterodimer. J Biol Chem 1995; 270:7717-23.
14. 14 Clauss M, Weich H, Breier G et al. The vascular endothelial growth factor receptor Flt-1 mediates biological activities. Implications for a functional role of placenta growth factor in monocyte activation and chemotaxis. J Biol Chem 1996; 271:17629-34.
15. 15 Park JE, Chen HH, Winer J, Houck KA, Ferrara N. Placenta growth factor - potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-I/ KDR. J Biol Chem 1994; 269:25646-54.
16. 16 Freemont AJ, Denton J. Atlas of synovial fluid cytopathology, Vol. 18. Higham, USA: Kluwer Academic Publishers, 1991.
17. 17 Webb NJA, Bottomley MJ, Watson CJ, Brenchley PEC. VEGF is released from platelets on blood clotting: implications for the measurement of VEGF in clinical disease. Clin Sci 1998; 94:395-405.
18. 18 Boyum A. Separation of white blood cells. Nature 1964; 204:793-4.
19. 19 Khaliq A, Li XF, Shams M et al. Localisation of placenta growth factor (PIGF) in human term placenta. Growth Factors 1996; 13:243-50.
20. 20 Olofsson B, Pajusola K, Kaipainen A et al. Vascular endothelial growth factor B, a novel growth factor for endothelial cells. Proc Natl Acad Sci USA 1996; 93:2576-81.
21. 21 Grimmond S, Lagencrantz J, Drinkwater C et al. Cloning and characterization of a human gene related to vascular endothelial growth factor. Genome Res 1996; 6:124-31.
22. 22 Joukov V, Pajusola K, Kaipainen A et al. A novel vascular endothelial growth factor, VEGF-C, is a ligand for Flt-4 (VEGFR-3) and KDR (VEGFR-2) receptor tyrosine kinases. EMBO J 1996; 15:290-8.
23. 23 Lee J, Gray A, Yuan J, Luoh SM, Avraham H, Wood WI. Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt-4. Proc Natl Acad Sci USA 1996; 93:1988-92.
24. 24 Yamada Y, Nezu J-I, Shimane M, Hirata Y. Molecular cloning of a novel vascular endothelial growth factor, VEGF-D. Genomics 1997; 42:483-8.
25. 25 Rocchigiani M, Lestingi M, Luddi A et al. Human FIGF. Cloning, gene structure, and mapping to chromosome Xp22.1 between PIGA and the GRPR genes. Genomics 1998; 47:207-16.
26. 26 Cao Y, Chen H, Zhou L et al. Heterodimers of placenta growth factor/ vascular endothelial growth factor. Endothelial activity, tumour cell expression, and high affinity binding to Flk-1/KDR. J Biol Chem 1996; 271:3154-62.
27. 27 Khaliq A, Foreman D, Ahmed A et al. Increased expression of placenta growth factor in proliferative diabetic retinopathy. Lab Invest 1998; 78:109-16.
28. 28 Viglietto G, Romano A, Manzo G et al. Upregulation of the angiogenic factors PIGF, VEGF and their receptors (Flt-1, Flk-1/KDR) by TSH in cultured thyrocytes and in the thyroid gland of thiouracil-fed rats suggest a TSH-dependent paracrine mechanism for goiter hypervascularization. Oncogene 1997; 15:2687-98.
29. 29 Ziche M, Maglione D, Rihatti D et al. Placenta growth factor-1 is chemotactic, mitogenic, and angiogenic. Lab Invest 1997; 76:517-31.
30. 30 Barillari G, Albonici L, Franzese O et al. The basic residues of placenta growth factor type 2 retrieve sequestered angiogenic factors into a soluble form: implications for tumor angiogenesis. Am J Pathol 1998; 152:1161-6.
31. 31 Cao Y, Ji WR. Qi P, Rosin A, Cao Y. Placenta growth factor: identification and characterisation of a novel isoform generated by RNA alternative splicing. Biophys Res Commun 1997; 235:493-8.
32. 32 Watson CJ, Webb NJA, Bottomley MJ, Brenchley PEC. Peripheral mononuclear cells express VEGF and the VEGF receptor flt-1. JASN 1996; 7:1725.
33. 33 Webb NJA, Myers CR, Watson CJ, Bottomley MJ, Brenchley PEC. Activated human neutrophils express vascular endothelial growth factor (VEGF). Cytokine 1998; 10:254-7.
34. 34 Sunderkotter C, Steinbrink K, Goebeler M, Bhardwaj R, Sorg C. Macrophages and angiogenesis. J Leuk Biol 1994; 55:410-22.
35. 35 Bottomley MJ, Webb NJA, Watson CJ, Holt PJL, Freemont AJ, Brenchley PEC. PBMCs from patients with rheumatoid arthritis spontaneously secrete VEGF: specific up-regulation by TNFα in synovial fluid. Clin Exp Immunol 1999; 117:171-6.
36. 36 Page-Thomas DP, Dingle JTM. In-vitro studies of rheumatoid synovium. Preliminary metabolic comparison between synovial membrane and villi. Br J Exp Pathol 1955; 36:195-8.
37. 37 Minchenko A, Bauer T, Salceda S, Caro J. Hypoxic stimulation of vascular endothelial growth factor expression in vivo and in vitro. Lab Invest 1994; 71:374-9.
38. 38 Namiki A, Brogi E, Kearney M et al. Hypoxia induces vascular endothelial growth factor in cultured human endothelial cells. J Biol Chem 1995; 270:31189-95.
39. 39 Shima DT, Deutsch U, D'Amour PA. Hypoxic induction of vascular endothelial growth factor (VEGF) in human epithelial cells is mediated by increases in mRNA stability. FEBS Letters 1995; 370:203-8.
40. 40 Oliver SJ, Cheng TP, Banquerigo ML, Brahn E. Suppression of collagen-induced arthritis by an angiogenesis inhibitor, AGM-1470, in combination with cyclosporin: reduction of VEGF. Cell Immunol 1995; 166:196-206.
41. 41 Brenchley PEC. Antagonising the expression of VEGF in pathological angiogenesis. Expert opinion on therapeutic patents. Exp Opin Ther Patents 1998; 8:1697-708.