Intravitreal aflibercept for treatment-resistant neovascular age-related macular degeneration

Ophthalmology

Volumn 121, Issue 1, 2014, Pages 188-192

  Chang, Andrew A ^a,b   Li, Haitao ^a   Broadhead, Geoffrey K ^a,b   Hong, Thomas ^a   Schlub, Timothy E ^c   Wijeyakumar, Wijeyanthy ^a,b   Zhu, Meidong ^b  

^a Sydney Institute of Health Sciences   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AFLIBERCEPT; BEVACIZUMAB; INDOCYANINE GREEN; RANIBIZUMAB;

AGED; ARTICLE; CATARACT; CENTRAL RETINAL THICKNESS; CLINICAL ARTICLE; CLINICAL TRIAL; DEEP VEIN THROMBOSIS; DRUG EFFICACY; DRUG TREATMENT FAILURE; FAINTNESS; FEMALE; FOLLOW UP; GASTRITIS; HEART ATRIUM FIBRILLATION; HEART INFARCTION; HUMAN; INDOCYANINE GREEN ANGIOGRAPHY; INTRAOCULAR PRESSURE; LOADING DRUG DOSE; MALE; MONOTHERAPY; OPEN STUDY; OUTCOME ASSESSMENT; PHOTODYNAMIC THERAPY; PNEUMONIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; RETINA FLUORESCEIN ANGIOGRAPHY; RETINA MACULA AGE RELATED DEGENERATION; RETINA MACULA CYSTOID EDEMA; RETINA MACULA HEMORRHAGE; RETINA NEOVASCULARIZATION; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY; SPONDYLOLISTHESIS; TREATMENT DURATION; VISUAL ACUITY;

AGED; ANGIOGENESIS INHIBITORS; DRUG RESISTANCE; FEMALE; FLUORESCEIN ANGIOGRAPHY; HUMANS; INTRAOCULAR PRESSURE; INTRAVITREAL INJECTIONS; MALE; PROSPECTIVE STUDIES; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; TOMOGRAPHY, OPTICAL COHERENCE; TREATMENT OUTCOME; VISUAL ACUITY; WET MACULAR DEGENERATION;

EID: 84891632111     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2013.08.035     Document Type: Article

References (14)

1. Eye Diseases Prevalence Research Group Causes and prevalence of visual impairment among adults in the United States Arch Ophthalmol 122 2004 477 485
2. C.C. Klaver, R.C. Wolfs, and J.R. Vingerling et al. Age-specific prevalence and causes of blindness and visual impairment in an older population: the Rotterdam Study Arch Ophthalmol 116 1998 653 658
3. L.H. Curtis, B.G. Hammill, and L.G. Qualls et al. Treatment patterns for neovascular age-related macular degeneration: analysis of 284 380 Medicare beneficiaries Am J Ophthalmol 153 2012 1116 1124
4. CATT Research Group Ranibizumab and bevacizumab for neovascular age-related macular degeneration N Engl J Med 364 2011 1897 1908
5. Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group, D.F. Martin, M.G. Maguire, and S.L. Fine et al. Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: two-year results Ophthalmology 119 2012 1388 1398
6. M.W. Stewart, and P.J. Rosenfeld Predicted biological activity of intravitreal VEGF Trap Br J Ophthalmol 92 2008 667 668
7. N. Papadopoulos, J. Martin, and Q. Ruan et al. Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab Angiogenesis 15 2012 171 185
8. J.S. Heier, D.M. Brown, and V. Chong et al. VIEW 1 and VIEW 2 Study Groups. Intravitreal aflibercept (VEGF Trap-Eye) in wet age-related macular degeneration Ophthalmology 119 2012 2537 2548
9. N. Kumar, M. Marsiglia, and S. Mrejen et al. Visual and anatomical outcomes of intravitreal aflibercept in eyes with persistent subfoveal fluid despite previous treatments with ranibizumab in patients with neovascular age-related macular degeneration Retina 33 2013 1605 1612
10. Y. Yonekawa, C. Andreoli, and J.B. Miller et al. Conversion to aflibercept for chronic refractory or recurrent neovascular age-related macular degeneration Am J Ophthalmol 156 2013 29 35
11. B. Bakall, J.C. Folk, and H.C. Boldt et al. Aflibercept therapy for exudative age-related macular degeneration resistant to bevacizumab and ranibizumab Am J Ophthalmol 156 2013 15 22
12. V.Y. Ho, S. Yeh, and T.W. Olsen et al. Short-term outcomes of aflibercept for neovascular age-related macular degeneration in eyes previously treated with other vascular endothelial growth factor inhibitors Am J Ophthalmol 156 2013 23 28
13. Age-Related Eye Disease Study Research Group The Age-Related Eye Disease Study (AREDS) system for classifying cataracts from photographs: AREDS report no. 4 Am J Ophthalmol 131 2001 167 175
14. A.P. Schachat Switching anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration Am J Ophthalmol 156 2013 1 2