Antimicrobial combinations: Bliss independence and loewe additivity derived from mechanistic multi-hit models

Philosophical Transactions of the Royal Society B: Biological Sciences

Volumn 371, Issue 1695, 2016, Pages

  Baeder, Desiree Y ^a   Yu, Guozhi ^b   Hozé, Nathanaël ^a   Rolff, Jens ^b,c   Regoes, Roland R ^a  

^a ETH ZURICH   (Switzerland)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c BERLIN BRANDENBURG INSTITUTE OF ADVANCED BIODIVERSITY RESEARCH BBIB   (Germany)

Author keywords

Antagonism; Antibiotics; Antimicrobial peptide responses; Mathematical modelling; Pharmacodynamic function; Synergy

Indexed keywords

ANTAGONISM; ANTIBIOTICS; ANTIMICROBIAL ACTIVITY; ARTHROPOD; BACTERIUM; BOTTOM-UP APPROACH; GROWTH RATE; NUMERICAL MODEL; PEPTIDE; SYNERGISM;

ARTHROPODA; BACTERIA (MICROORGANISMS);

ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; INSECT PROTEIN;

ANIMAL; BACTERIUM; BIOLOGICAL MODEL; DRUG EFFECTS; INSECT; MICROBIOLOGY;

ANIMALS; ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIA; INSECT PROTEINS; INSECTS; MODELS, BIOLOGICAL;

EID: 84966430924     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2015.0294     Document Type: Article

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